Download or read book Auto Immunity and Auto Immune Disease written by Burnet MacFarlane and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1957 or thereabouts I became impressed with how immunity could be looked at as a process of Darwinian selection amongst the circulating lymphoid cells of the body. The clonal selection theory which grew out of this has been generally accepted in principle by immunologists, but I do not feel that its full implications in relation to pathology have yet been widely realized. In a previous book, Immunological Surveillance, I have tried to apply the approach to cancer immunity. This is a basically similar attempt to look at auto-immune disease from the same Darwinian point of view. Anyone who attempts to produce acceptable general statements about complex biological and clinical phenomena must have a certain sense of guilt. No biological phenomenon can ever be completely, or even adequately, described. There can, at best, only be a progressive improvement in the acceptability, the intellectual elegance, or the practical usefulness of the working generalizations that can be produced. Any attempt to write at this interpretative level can easily be brushed aside as superficial, unnecessary, and liable to be proved wrong or irrelevant by new developments. It is anathema to many good professional scientists and their objections are real enough.

Download or read book New Research on Autoantibodies written by Claude T. Petrelli and published by Nova Publishers. This book was released on 2008 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoantibodies are a group of antibodies (immune proteins) that mistakenly target and damage specific tissues or organs of the body. One or more autoantibodies may be produced by a person's immune system when it fails to distinguish between "self" and "non-self" proteins. Usually the immune system is able to discriminate by recognising foreign substances (non-self) and ignoring the body's own cells (self), yet not overreact to non-threatening substances such as foods, dust and pollen, or beneficial microorganisms. It creates antibodies only when it perceives what it has been exposed to as a threat (non-self). When the immune system ceases to recognise one or more of the body's normal constituents as "self", it may produce autoantibodies that attack its own cells, tissues, and/or organs, causing inflammation and damage. The causes of this inappropriate action are varied and are not well understood, often resulting in a chronic auto-immune disorder. While there is not a direct link, it is thought that many cases of autoantibody production are due to a genetic predisposition combined with an environmental trigger (such as a viral illness or a prolonged exposure to certain toxic chemicals). Some families have been shown to have a high prevalence of auto-immune conditions; however, individual family members may have different auto-immune disorders or may never develop an auto-immune condition. Researchers believe that there may also be a hormonal component to the cause as many of the auto-immune conditions are more common in women of childbearing age. This book presents leading research from throughout the world.

Download or read book AUTO IMMUNE FR written by William AMZALLAG and published by Lulu.com. This book was released on 2019-06-03 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Les maladies auto-immunes sont des maladies liées à une fonction particulière qu'on appelle auto-immunité . Lorsque notre système immunitaire attaque et détruit nos propres organes, nos fonctions, nos cellules, nos articulations, nos vaisseaux, alors on peut parler de maladies auto-immunes et d'auto-immunité. Elles représentent aujourd'hui la troisième cause de toutes les maladies après les affections cardio-vasculaires et les cancers. Il n'y a pas de véritable traitement de fond de ces maladies et les médicaments utilisés sont surtout destinés à réduire les capacités de notre système immunitaire avec toutes les consequences délétères que cela représente. Et pourtant il existe des méthodes simples, naturelles, efficaces et surtout scientifiquement prouvées qui sont à notre disposition. L'auteur explique pourquoi la validité de ces méthodes est freinée par l'industrie pharmaceutique et comment les appliquer avec succès.

Download or read book Maladies Auto immunes written by Tron Francois Tron and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Auto immunity and Auto immune Disease written by Sir Frank Macfarlane Burnet and published by . This book was released on 1972 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Multi systemic Auto immune Diseases written by Louis Kater and published by Elsevier Science & Technology. This book was released on 1995 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The views of a group of specialists on multi-systemic auto-immune diseases are brought together in this book, which describes a selection of the diseases according to what has been called an integrated approach. The volume includes descriptions of the clinical picture, histology, laboratory work-up necessary for diagnosis, differential diagnosis, clarification of the mechanisms operative in pathophysiology, specific guidelines for application of immunological laboratory investigations, and practical approaches and advice for therapy. It also gives personal views of the contributors as to which regimen to recommend in a certain situation. internal medicine, dermatology, rheumatology, neurology or immunology.

Download or read book Chronic Illness Vulnerability and Social Work written by Liz Price and published by Routledge. This book was released on 2015-05-01 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whilst the body has recently assumed greater sociological significance, there has been less engagement in social work and social care on the bodily experience of health, illness and disease. This innovative volume redresses the balance by exploring chronic illness and social work, through the specific lens of autoimmunity, engaging in wider debates around vulnerability, resistance and the lived experience of ongoing ill-health. Moving beyond existing conceptualisations of vulnerability as an issue of mental distress, ageing, child protection and poverty, Price and Walker demonstrate the role that society has to play in actively engaging the physical body, rather than working around and through it. The book focuses on auto-immune conditions such as lupus, multiple sclerosis, rheumatoid arthritis and scleroderma. Conditions like these allow for an exploration of the materiality of illness which exacerbates social and economic vulnerability and may precipitate personal and social crises, requiring a variety of interventions and support. The risks and challenges associated with chronic illness include disruptions to a sense of self and identity, altered relationships and the renegotiation of roles and responsibilities in a variety of relationships in addition to an economic impact, with the potential for disruption to employment status and financial insecurity. This text opens up a range of debates around some of the central concerns of the social work profession, including vulnerability, ill-health, and independence. It will be of interest to scholars and students of social work, nursing, disability studies, medicine and the social sciences.

Download or read book Auto Immunity and Auto Immune Disease written by Burnet MacFarlane and published by Springer. This book was released on 1972-06-30 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1957 or thereabouts I became impressed with how immunity could be looked at as a process of Darwinian selection amongst the circulating lymphoid cells of the body. The clonal selection theory which grew out of this has been generally accepted in principle by immunologists, but I do not feel that its full implications in relation to pathology have yet been widely realized. In a previous book, Immunological Surveillance, I have tried to apply the approach to cancer immunity. This is a basically similar attempt to look at auto-immune disease from the same Darwinian point of view. Anyone who attempts to produce acceptable general statements about complex biological and clinical phenomena must have a certain sense of guilt. No biological phenomenon can ever be completely, or even adequately, described. There can, at best, only be a progressive improvement in the acceptability, the intellectual elegance, or the practical usefulness of the working generalizations that can be produced. Any attempt to write at this interpretative level can easily be brushed aside as superficial, unnecessary, and liable to be proved wrong or irrelevant by new developments. It is anathema to many good professional scientists and their objections are real enough.

Download or read book Auto immunity in the Endocrine System written by R. Volpe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present monograph will concern itself with those disorders of the endocrine system, either associated with destruction, interference with function or hyper function, which are considered to be due to auto-immune processes. Endocrinopathies Non-endocrine auto-immune disorders associated with the endocrinopathies Graves' (Basedow's, Parry's) disease Pernicious anaemia Hashimoto's thyroiditis Vitiligo Idiopathic Addison's disease Myaesthenia gravis Insulinopenic diabetes mellitus Sjogren's syndrome Auto-immune oophoritis and orchitis Rheumatoid arthritis Auto-immune hypoparathyroidism Idiopathic thrombocytopenic purpura Auto-immune hypophysitis Chronic active hepatitis Possibly some cases of infertility Primary biliary cirrhosis due to anti-sperm antibodies Reproduced with permission from Volpe (1977) The above table indicates those organ-specific endocrinopathies considered to be due to auto-immune factors, as well as those non-endocrine, organ-specific auto-immune disorders which may be associated with them (Volpe 1977). It is evident that such disorders, occurring without any obvious external cause, raise the very elementary question of how immune processes directed against self constituents could be initiated. Generally, of course, the immune system acts as a regulatory and defence mechanism, and disorders of auto-immunity represent breakdowns in this regulatory system. The following chapters will be concerned with the individual components ofthe endocrine system so affected by auto-immune processes; it will first be necessary to provide an initial chapter for the purpose of summarizing some general principles of immunology, in order to place the immune disorders of the endocrine system in context.

Download or read book The Autoimmune Diseases written by Ian R. Mackay and published by Elsevier. This book was released on 2006-05-15 with total page 1160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since publication of the Third Edition in 1998, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This Fourth Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels. New to This Edition: * Tissue-specific interventions to arrest or "cure" autoimmune disease * Bone marrow eradication and replacement * Both basic science and clinical medicine is covered * Boxed points to emphasize key features of each chapter

Download or read book Mechanisms of Lymphocyte Activation and Immune Regulation VIII written by Sudhir Gupta and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. This book covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies. This book should be useful for immunologists, molecular biologists, rheumatologists, and clinical scientists.

Download or read book Autoimmunity written by Fynn L. Vogel and published by Nova Science Publishers. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmunity is the failure of an organism to recognise its own constituent parts (down to the sub-molecular levels) as self, which results in an immune response against its own cells and tissues. Any disease that results from such an aberrant immune response is termed an auto-immune disease such as the disease multiple sclerosis or heart disease. This book provides new and important research on several auto-immune disorders and their processes.

Download or read book Healing Auto Immune Diseases the Gerson Way written by Charlotte Gerson and published by . This book was released on 2017-04-04 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: booklet describing the cause and reversal of "auto-immune" diseases using the Gerson Therapy

Download or read book The Immune Mystery written by Dr. Anita Kåss and published by Greystone Books Ltd. This book was released on 2021-05-18 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: A page-turning and powerful medical mystery for readers of Diagnosis by Lisa Sanders and The Beauty in Breaking by Michele Harper More than 20 million Americans have autoimmune diseases, which occur when the immune system attacks the body. Autoimmune diseases are often misdiagnosed by doctors and overlooked by medical researchers. Almost all affect women more often than men. The Immune Mystery follows doctor and researcher Anita Kåss’s quest to solve the autoimmune puzzle, beginning with the premature death of her mother, who developed rheumatoid arthritis shortly after giving birth to Anita. As a child, Anita vowed to study the illness and one day find a cure. Becoming a respected doctor and researcher, Anita devoted herself to studying auto-immune disorders like rheumatoid arthritis, lupus, and multiple sclerosis. Why do so many autoimmune diseases start to show symptoms during and after childbirth, perimenopause, and menopause? Could autoimmune diseases be linked to our changing hormones? Despite the groundbreaking nature of her research, Anita had to fight for her ideas against the conventional wisdom and casual sexism of the medical industry––even as she made a discovery that earned her a record-breaking US$95 million pharmaceutical deal. A compelling blend of incredible determination and cutting-edge science, The Immune Mystery changes the way we think about autoimmune diseases. Anita offers solace to patients struggling with questions about their health, and introduces a powerful new voice in medical storytelling.

Download or read book Diagnostic Criteria in Autoimmune Diseases written by Yehuda Shoenfeld and published by Springer Science & Business Media. This book was released on 2010-06-08 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA – up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.

Download or read book Type I Interferon in Autoimmune Diseases and Its Clinical Applications written by Yihong Yao and published by Nova Science Publishers. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Auto-immune diseases such as systemic lupus erythematosus (SLE), Sjögren's syndrome, psoriasis, scleroderma (SSc) and myositis are heterogeneous disorders that result from interactions between genetic and environmental factors. Type I interferons (IFNs), especially IFN-α/β, have multiple biological functions including anti-viral and anti-bacterial properties, immuno-modulation, anti-proliferation, and intensive studies over decades have also revealed important roles in auto-immunity and cancer. Sustained Type I IFN elevation has been implicated in immune responses against self-antigens and tissue damage, which has led to the hypothesis that type I IFN might play a critical role in the pathogenesis of some auto-immune and inflammatory diseases. This book provides an overview of many key topics surrounding type I IFNs, beginning with detailed discussion of the type I IFN signalling pathway, the interplay between components that regulate this pathway, its involvement in auto-immunity, and a detailed review of the roles of type I IFNs in a series of well characterised inflammatory and auto-immune diseases.

Download or read book Body Harmony written by Terry Willard and published by Key Porter Books. This book was released on 2003 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: President of the Canadian Association of Herbal Practitioners and bestselling author of Dr. Terry Willard’s Encyclopedia of Herbs, Dr. Willard offers insight into why more and more people are becoming afflicted by auto-immune diseases and how to react. Vibrational medicine is a newly emerging model of medicine that takes into account the body’s electromagnetic, or life-force energies, which are also known in other cultures as chi, ki, or prana. While the recognition of such an energy force is not new, this book is the first to recognize vibrational medicine as an essential component in the treatment and recovery of auto-immune disorders. Using case studies from his twenty-five-year practice, Dr. Willard outlines the common patterns that lead to auto-immune syndromes like as chronic fatigue syndrome, fibromyalgia, irritable bowel syndrome, and allergies and explores the complex connection between the mind and the body. He also outlines how people can recover from auto-immune diseases using a combination of vibrational medicine, herbal remedies and mind-body therapies. Body Harmony How to Resist and Recover from Auto Immune Diseases offers long-term solutions for all those suffering from auto-immune-related illnesses. This book is the perfect resource for anyone who is interested in healing their immune systems and achieving optimum health. (August 2003)