Download or read book Machine Learning and Network Driven Integrative Genomics written by Mehdi Pirooznia and published by Frontiers Media SA. This book was released on 2021-04-29 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Deep Learning for Genomics written by Upendra Kumar Devisetty and published by Packt Publishing Ltd. This book was released on 2022-11-11 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn concepts, methodologies, and applications of deep learning for building predictive models from complex genomics data sets to overcome challenges in the life sciences and biotechnology industries Key FeaturesApply deep learning algorithms to solve real-world problems in the field of genomicsExtract biological insights from deep learning models built from genomic datasetsTrain, tune, evaluate, deploy, and monitor deep learning models for enabling predictions in genomicsBook Description Deep learning has shown remarkable promise in the field of genomics; however, there is a lack of a skilled deep learning workforce in this discipline. This book will help researchers and data scientists to stand out from the rest of the crowd and solve real-world problems in genomics by developing the necessary skill set. Starting with an introduction to the essential concepts, this book highlights the power of deep learning in handling big data in genomics. First, you'll learn about conventional genomics analysis, then transition to state-of-the-art machine learning-based genomics applications, and finally dive into deep learning approaches for genomics. The book covers all of the important deep learning algorithms commonly used by the research community and goes into the details of what they are, how they work, and their practical applications in genomics. The book dedicates an entire section to operationalizing deep learning models, which will provide the necessary hands-on tutorials for researchers and any deep learning practitioners to build, tune, interpret, deploy, evaluate, and monitor deep learning models from genomics big data sets. By the end of this book, you'll have learned about the challenges, best practices, and pitfalls of deep learning for genomics. What you will learnDiscover the machine learning applications for genomicsExplore deep learning concepts and methodologies for genomics applicationsUnderstand supervised deep learning algorithms for genomics applicationsGet to grips with unsupervised deep learning with autoencodersImprove deep learning models using generative modelsOperationalize deep learning models from genomics datasetsVisualize and interpret deep learning modelsUnderstand deep learning challenges, pitfalls, and best practicesWho this book is for This deep learning book is for machine learning engineers, data scientists, and academicians practicing in the field of genomics. It assumes that readers have intermediate Python programming knowledge, basic knowledge of Python libraries such as NumPy and Pandas to manipulate and parse data, Matplotlib, and Seaborn for visualizing data, along with a base in genomics and genomic analysis concepts.

Download or read book Artificial Intelligence written by and published by BoD – Books on Demand. This book was released on 2019-07-31 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial intelligence (AI) is taking on an increasingly important role in our society today. In the early days, machines fulfilled only manual activities. Nowadays, these machines extend their capabilities to cognitive tasks as well. And now AI is poised to make a huge contribution to medical and biological applications. From medical equipment to diagnosing and predicting disease to image and video processing, among others, AI has proven to be an area with great potential. The ability of AI to make informed decisions, learn and perceive the environment, and predict certain behavior, among its many other skills, makes this application of paramount importance in today's world. This book discusses and examines AI applications in medicine and biology as well as challenges and opportunities in this fascinating area.

Download or read book Handbook of Machine Learning Applications for Genomics written by Sanjiban Sekhar Roy and published by Springer Nature. This book was released on 2022-06-23 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, machine learning is playing a pivotal role in the progress of genomics. The applications of machine learning are helping all to understand the emerging trends and the future scope of genomics. This book provides comprehensive coverage of machine learning applications such as DNN, CNN, and RNN, for predicting the sequence of DNA and RNA binding proteins, expression of the gene, and splicing control. In addition, the book addresses the effect of multiomics data analysis of cancers using tensor decomposition, machine learning techniques for protein engineering, CNN applications on genomics, challenges of long noncoding RNAs in human disease diagnosis, and how machine learning can be used as a tool to shape the future of medicine. More importantly, it gives a comparative analysis and validates the outcomes of machine learning methods on genomic data to the functional laboratory tests or by formal clinical assessment. The topics of this book will cater interest to academicians, practitioners working in the field of functional genomics, and machine learning. Also, this book shall guide comprehensively the graduate, postgraduates, and Ph.D. scholars working in these fields.

Download or read book Big Data in Omics and Imaging written by Momiao Xiong and published by CRC Press. This book was released on 2018-06-14 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Big Data in Omics and Imaging: Integrated Analysis and Causal Inference addresses the recent development of integrated genomic, epigenomic and imaging data analysis and causal inference in big data era. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), genome-wide expression studies (GWES), and epigenome-wide association studies (EWAS), the overall contribution of the new identified genetic variants is small and a large fraction of genetic variants is still hidden. Understanding the etiology and causal chain of mechanism underlying complex diseases remains elusive. It is time to bring big data, machine learning and causal revolution to developing a new generation of genetic analysis for shifting the current paradigm of genetic analysis from shallow association analysis to deep causal inference and from genetic analysis alone to integrated omics and imaging data analysis for unraveling the mechanism of complex diseases. FEATURES Provides a natural extension and companion volume to Big Data in Omic and Imaging: Association Analysis, but can be read independently. Introduce causal inference theory to genomic, epigenomic and imaging data analysis Develop novel statistics for genome-wide causation studies and epigenome-wide causation studies. Bridge the gap between the traditional association analysis and modern causation analysis Use combinatorial optimization methods and various causal models as a general framework for inferring multilevel omic and image causal networks Present statistical methods and computational algorithms for searching causal paths from genetic variant to disease Develop causal machine learning methods integrating causal inference and machine learning Develop statistics for testing significant difference in directed edge, path, and graphs, and for assessing causal relationships between two networks The book is designed for graduate students and researchers in genomics, epigenomics, medical image, bioinformatics, and data science. Topics covered are: mathematical formulation of causal inference, information geometry for causal inference, topology group and Haar measure, additive noise models, distance correlation, multivariate causal inference and causal networks, dynamic causal networks, multivariate and functional structural equation models, mixed structural equation models, causal inference with confounders, integer programming, deep learning and differential equations for wearable computing, genetic analysis of function-valued traits, RNA-seq data analysis, causal networks for genetic methylation analysis, gene expression and methylation deconvolution, cell –specific causal networks, deep learning for image segmentation and image analysis, imaging and genomic data analysis, integrated multilevel causal genomic, epigenomic and imaging data analysis.

Download or read book Big Data Analytics in Genomics written by Ka-Chun Wong and published by Springer. This book was released on 2016-10-24 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume explores the emerging intersection between big data analytics and genomics. Recent sequencing technologies have enabled high-throughput sequencing data generation for genomics resulting in several international projects which have led to massive genomic data accumulation at an unprecedented pace. To reveal novel genomic insights from this data within a reasonable time frame, traditional data analysis methods may not be sufficient or scalable, forcing the need for big data analytics to be developed for genomics. The computational methods addressed in the book are intended to tackle crucial biological questions using big data, and are appropriate for either newcomers or veterans in the field.This volume offers thirteen peer-reviewed contributions, written by international leading experts from different regions, representing Argentina, Brazil, China, France, Germany, Hong Kong, India, Japan, Spain, and the USA. In particular, the book surveys three main areas: statistical analytics, computational analytics, and cancer genome analytics. Sample topics covered include: statistical methods for integrative analysis of genomic data, computation methods for protein function prediction, and perspectives on machine learning techniques in big data mining of cancer. Self-contained and suitable for graduate students, this book is also designed for bioinformaticians, computational biologists, and researchers in communities ranging from genomics, big data, molecular genetics, data mining, biostatistics, biomedical science, cancer research, medical research, and biology to machine learning and computer science. Readers will find this volume to be an essential read for appreciating the role of big data in genomics, making this an invaluable resource for stimulating further research on the topic.

Download or read book Machine Learning and Systems Biology in Genomics and Health written by Shailza Singh and published by Springer Nature. This book was released on 2022-02-04 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the application of machine learning in genomics. Machine Learning offers ample opportunities for Big Data to be assimilated and comprehended effectively using different frameworks. Stratification, diagnosis, classification and survival predictions encompass the different health care regimes representing unique challenges for data pre-processing, model training, refinement of the systems with clinical implications. The book discusses different models for in-depth analysis of different conditions. Machine Learning techniques have revolutionized genomic analysis. Different chapters of the book describe the role of Artificial Intelligence in clinical and genomic diagnostics. It discusses how systems biology is exploited in identifying the genetic markers for drug discovery and disease identification. Myriad number of diseases whether be infectious, metabolic, cancer can be dealt in effectively which combines the different omics data for precision medicine. Major breakthroughs in the field would help reflect more new innovations which are at their pinnacle stage. This book is useful for researchers in the fields of genomics, genetics, computational biology and bioinformatics.

Download or read book Integrative Genomics and Network Biology in Livestock and other Domestic Animals written by David E. MacHugh and published by Frontiers Media SA. This book was released on 2020-09-11 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Download or read book Future of AI in Biomedicine and Biotechnology written by Khade, Shankar Mukundrao and published by IGI Global. This book was released on 2024-05-30 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The healthcare industry is grappling with numerous challenges, including rising costs, inefficiencies in service delivery, and the need for personalized treatment approaches. Traditional healthcare management and delivery methods must be improved in addressing these issues, leading to a growing demand for innovative solutions. Additionally, the exponential growth of medical data and the complexity of biomedical research and biotechnology presents a daunting challenge in harnessing this data effectively for improved patient care and medical advancements. There is a pressing need for a comprehensive understanding of how artificial intelligence (AI) can be leveraged to tackle these challenges and drive meaningful change in the healthcare sector. Future of AI in Biomedicine and Biotechnology offers a timely and insightful solution to the challenges faced by the healthcare industry. This book is not just a theoretical exploration; it is a practical roadmap for healthcare professionals, researchers, policymakers, and entrepreneurs seeking to navigate the complexities of AI in healthcare. By exploring the intersection of AI with biomedical sciences and biotechnology, this book provides a comprehensive guide to harnessing the power of AI for transformative healthcare innovation.

Download or read book Data Driven Science for Clinically Actionable Knowledge in Diseases written by Daniel Catchpoole and published by CRC Press. This book was released on 2023-12-06 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data-driven science has become a major decision-making aid for the diagnosis and treatment of disease. Computational and visual analytics enables effective exploration and sense making of large and complex data through the deployment of appropriate data science methods, meaningful visualisation and human-information interaction. This edited volume covers state-of-the-art theory, method, models, design, evaluation and applications in computational and visual analytics in desktop, mobile and immersive environments for analysing biomedical and health data. The book is focused on data-driven integral analysis, including computational methods and visual analytics practices and solutions for discovering actionable knowledge in support of clinical actions in real environments. By studying how data and visual analytics have been implemented into the healthcare domain, the book demonstrates how analytics influences the domain through improving decision making, specifying diagnostics, selecting the best treatments and generating clinical certainty.

Download or read book Machine Learning in Dentistry written by Ching-Chang Ko and published by Springer Nature. This book was released on 2021-07-24 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews all aspects of the use of machine learning in contemporary dentistry, clearly explaining its significance for dental imaging, oral diagnosis and treatment, dental designs, and dental research. Machine learning is an emerging field of artificial intelligence research and practice in which computer agents are employed to improve perception, cognition, and action based on their ability to “learn”, for example through use of big data techniques. Its application within dentistry is designed to promote personalized and precision patient care, with enhancement of diagnosis and treatment planning. In this book, readers will find up-to-date information on different machine learning tools and their applicability in various dental specialties. The selected examples amply illustrate the opportunities to employ a machine learning approach within dentistry while also serving to highlight the associated challenges. Machine Learning in Dentistry will be of value for all dental practitioners and researchers who wish to learn more about the potential benefits of using machine learning techniques in their work.

Download or read book Deep Learning for the Life Sciences written by Bharath Ramsundar and published by "O'Reilly Media, Inc.". This book was released on 2019-04-10 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep learning has already achieved remarkable results in many fields. Now it’s making waves throughout the sciences broadly and the life sciences in particular. This practical book teaches developers and scientists how to use deep learning for genomics, chemistry, biophysics, microscopy, medical analysis, and other fields. Ideal for practicing developers and scientists ready to apply their skills to scientific applications such as biology, genetics, and drug discovery, this book introduces several deep network primitives. You’ll follow a case study on the problem of designing new therapeutics that ties together physics, chemistry, biology, and medicine—an example that represents one of science’s greatest challenges. Learn the basics of performing machine learning on molecular data Understand why deep learning is a powerful tool for genetics and genomics Apply deep learning to understand biophysical systems Get a brief introduction to machine learning with DeepChem Use deep learning to analyze microscopic images Analyze medical scans using deep learning techniques Learn about variational autoencoders and generative adversarial networks Interpret what your model is doing and how it’s working

Download or read book Artificial Intelligence Bioinformatics Development and Application of Tools for Omics and Inter Omics Studies written by Angelo Facchiano and published by Frontiers Media SA. This book was released on 2020-06-18 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Issues in Artificial Intelligence Robotics and Machine Learning 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 1211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Artificial Intelligence, Robotics and Machine Learning: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Expert Systems. The editors have built Issues in Artificial Intelligence, Robotics and Machine Learning: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Expert Systems in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Artificial Intelligence, Robotics and Machine Learning: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Knowledge and Systems Engineering written by Viet-Ha Nguyen and published by Springer. This book was released on 2014-09-29 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains papers presented at the Sixth International Conference on Knowledge and Systems Engineering (KSE 2014), which was held in Hanoi, Vietnam, during 9–11 October, 2014. The conference was organized by the University of Engineering and Technology, Vietnam National University, Hanoi. Besides the main track of contributed papers, this proceedings feature the results of four special sessions focusing on specific topics of interest and three invited keynote speeches. The book gathers a total of 51 carefully reviewed papers describing recent advances and development on various topics including knowledge discovery and data mining, natural language processing, expert systems, intelligent decision making, computational biology, computational modeling, optimization algorithms, and industrial applications.

Download or read book Towards Integrative Machine Learning and Knowledge Extraction written by Andreas Holzinger and published by Springer. This book was released on 2017-10-27 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: The BIRS Workshop “Advances in Interactive Knowledge Discovery and Data Mining in Complex and Big Data Sets” (15w2181), held in July 2015 in Banff, Canada, was dedicated to stimulating a cross-domain integrative machine-learning approach and appraisal of “hot topics” toward tackling the grand challenge of reaching a level of useful and useable computational intelligence with a focus on real-world problems, such as in the health domain. This encompasses learning from prior data, extracting and discovering knowledge, generalizing the results, fighting the curse of dimensionality, and ultimately disentangling the underlying explanatory factors in complex data, i.e., to make sense of data within the context of the application domain. The workshop aimed to contribute advancements in promising novel areas such as at the intersection of machine learning and topological data analysis. History has shown that most often the overlapping areas at intersections of seemingly disparate fields are key for the stimulation of new insights and further advances. This is particularly true for the extremely broad field of machine learning.

Download or read book Systems Medicine written by and published by Academic Press. This book was released on 2020-08-24 with total page 1571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice. Encyclopedic coverage: ‘one-stop’ resource for access to information written by world-leading scholars in the field of Systems Biology and Systems Medicine, with easy cross-referencing of related articles to promote understanding and further research Authoritative: the whole work is authored and edited by recognized experts in the field, with a range of different expertise, ensuring a high quality standard Digitally innovative: Hyperlinked references and further readings, cross-references and diagrams/images will allow readers to easily navigate a wealth of information