Download or read book Ludwik Hirszfeld Institute of Immunology and Experimental Therapy written by Polska Akademia Nauk. Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda (Wrocław). and published by . This book was released on 1988 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ludwik Hirszfeld Institute of Immunology and Experimental Therapy written by Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda (Polska Akademia Nauk) and published by . This book was released on 1988 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ludwik Hirszfeld Institute of Immunology and Experimental Therapy written by Polska Akademia Nauk. Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda (Wrocław). and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Archives of Immunology and Experimental Therapy written by Polish Academy of Sciences, Wroclaw. Scientific Council of the Ludwik Hirszfeld. Institute of Immunology and Experimental Therapy and published by . This book was released on 1962 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Papers Presented at the Conference on Molecular Biology Techniques in Clinical Immunology and Transplantation written by and published by . This book was released on 1995 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Phage Therapy A Practical Approach written by Andrzej Górski and published by Springer Nature. This book was released on 2019-10-25 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a detailed yet clear insight into the current state of the art of the therapeutic application of bacteriophages in different conditions. The authors bring in their practical expertise within their respective fields of expertise and provide an excellent overview of the potential and actual use of phage therapy. Topics like economic feasibility compared to traditional antibiotics and also regulatory issues are discussed in far detail. This new volume is therefore a valuable resource for individuals engaged in the medical application of novel phage therapies.
Download or read book Phage Therapy Past Present and Future written by Stephen T. Abedon and published by Frontiers Media SA. This book was released on 2017-09-05 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically, the first observation of a transmissible lytic agent that is specifically active against a bacterium (Bacillus anthracis) was by a Russian microbiologist Nikolay Gamaleya in 1898. At that time, however, it was too early to make a connection to another discovery made by Dmitri Ivanovsky in 1892 and Martinus Beijerinck in 1898 on a non-bacterial pathogen infecting tobacco plants. Thus the viral world was discovered in two of the three domains of life, and our current understanding is that viruses represent the most abundant biological entities on the planet. The potential of bacteriophages for infection treatment have been recognized after the discoveries by Frederick Twort and Felix d’Hérelle in 1915 and 1917. Subsequent phage therapy developments, however, have been overshadowed by the remarkable success of antibiotics in infection control and treatment, and phage therapy research and development persisted mostly in the former Soviet Union countries, Russia and Georgia, as well as in France and Poland. The dramatic rise of antibiotic resistance and especially of multi-drug resistance among human and animal bacterial pathogens, however, challenged the position of antibiotics as a single most important pillar for infection control and treatment. Thus there is a renewed interest in phage therapy as a possible additive/alternative therapy, especially for the infections that resist routine antibiotic treatment. The basis for the revival of phage therapy is affected by a number of issues that need to be resolved before it can enter the arena, which is traditionally reserved for antibiotics. Probably the most important is the regulatory issue: How should phage therapy be regulated? Similarly to drugs? Then the co-evolving nature of phage-bacterial host relationship will be a major hurdle for the production of consistent phage formulae. Or should we resort to the phage products such as lysins and the corresponding engineered versions in order to have accurate and consistent delivery doses? We still have very limited knowledge about the pharmacodynamics of phage therapy. More data, obtained in animal models, are necessary to evaluate the phage therapy efficiency compared, for example, to antibiotics. Another aspect is the safety of phage therapy. How do phages interact with the immune system and to what costs, or benefits? What are the risks, in the course of phage therapy, of transduction of undesirable properties such as virulence or antibiotic resistance genes? How frequent is the development of bacterial host resistance during phage therapy? Understanding these and many other aspects of phage therapy, basic and applied, is the main subject of this Topic.
Download or read book Hurdles for Phage Therapy PT to Become a Reality written by Harald Brüssow and published by MDPI. This book was released on 2019-08-20 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alternative treatment modes for antibiotic-resistant bacterial pathogens have become a public health priority. Bacteriophages are bacterial viruses that infect and lyse bacterial cells. Since bacteriophages are frequently bacterial host species-specific and can often also infect antibiotic-resistant bacterial cells, they could represent ideal antimicrobials for fighting the antibiotic resistance crisis. The medical use of bacteriophages has become known as phage therapy. It is widely used in Russia, where phage cocktails are sold in pharmacies as an over-the-counter drug. However, no phage product has been registered for medical purposes outside of the former Soviet Union. The current Special Issue of Viruses contains a collection of papers from opinion leaders in the field who explore hurdles to the introduction of phage therapy in western countries. The articles cover diverse topics ranging from patent to regulatory issues, the targeting of suitable bacterial infections, and the selection and characterization of safe and efficient phage cocktails. Phage resistance is discussed, and gaps in our knowledge of phage–bacterium interactions in the mammalian body are revealed, while other articles explore the use of phages in food production and processing.
Download or read book Index of NLM Serial Titles written by National Library of Medicine (U.S.) and published by . This book was released on 1984 with total page 1516 pages. Available in PDF, EPUB and Kindle. Book excerpt: A keyword listing of serial titles currently received by the National Library of Medicine.
Download or read book Issues in Allied Fields of Medicine 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Allied Fields of Medicine / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Allied Fields of Medicine. The editors have built Issues in Allied Fields of Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Allied Fields of Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Allied Fields of Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Biological Factors Advances in Research and Application 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 1177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Factors—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biological Factors. The editors have built Biological Factors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biological Factors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Biological Factors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Spontaneous Abortion New Insights for the Healthcare Professional 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spontaneous Abortion: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Spontaneous Abortion in a concise format. The editors have built Spontaneous Abortion: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Spontaneous Abortion in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Spontaneous Abortion: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Estrogen Receptors Advances in Research and Application 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Estrogen Receptors: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Estrogen Receptors in a concise format. The editors have built Estrogen Receptors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Estrogen Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Estrogen Receptors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Bacteriophages written by Wacław T. Szybalski and published by Academic Press. This book was released on 2012 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, the first of a two-part series, covers topics including historical, ecological and evolutionary considerations, genomics and molecular biology, and interaction of phages with their hosts.
Download or read book Advances in Phage Therapy Present Challenges and Future Perspectives written by Andrzej Gorski and published by Frontiers Media SA. This book was released on 2021-08-02 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is dedicated to Prof. Elisabeth Kutter on the occasion of her 80th birthday. Dr. Kutter’s career as a phage scientist has extended nearly 60 years. She has been a pioneer as a woman in science. She started to work with phage at the University of Rochester, New York working with Dr. Wiberg on radioisotopes making excellent progress in the field – progress which was even cited in Luria’s 1969 Nobel Prize talk. Betty first encountered phage therapy during a visit to Georgia in 1990 which was part of a longer stay in the former Soviet Union under a US-USSR research exchange program. Dr. Kutter was one of the first Americans to advocate for phage therapy in the post antibiotic era. Betty started hosting the Evergreen International Phage meetings in Olympia, Washington, from 1975 onward, which helped to develop a strong phage community with participation increasing over the years to 350 at the 23 rd biannual last year. Betty continues to be an active member in the phage community, sharing her experience and working with all of us toward her ultimate goal of making phage therapy available worldwide thus reducing the burden caused by antibiotic resistant bacterial infections.
Download or read book Peripheral Markers of Immune Response in Major Psychiatric Disorders Where Are We Now and Where Do We Want to Be written by Błażej Misiak and published by Frontiers Media SA. This book was released on 2019-04-03 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major psychiatric disorders, including schizophrenia, bipolar disorder and major depression represent complex phenotypes with imprecise diagnostic boundaries. It has been found that these disorders can be characterized by a number of peripheral immune-inflammatory alterations, including, i.e. elevated levels of pro-inflammatory cytokines, increased levels of specific and non-specific antibodies or abnormal counts of lymphocyte subpopulations. Although it has been found that major psychiatric disorders share similar dysregulations of immune-inflammatory response, recent studies have also clearly demonstrated that some differences can be indicated. Interestingly, certain immune-inflammatory disturbances appear to be state markers, since they occur in acute relapse and normalize following pharmacological treatment, while the rest represents trait markers that remain stable regardless of treatment. It is also important to note that peripheral immune-inflammatory markers have been associated with psychopathological manifestation of major psychiatric disorders, response to treatment and long-term outcomes. However, it remains unclear what is the origin of peripheral inflammation in psychiatric disorders. To date, several mechanisms have been proposed, including the gut-brain axis dysregulation, infections in the neurodevelopmental period or immunogenetic factors. This eBook summarizes current evidence from studies investigating peripheral inflammation in schizophrenia, bipolar disorder, major depression and post-traumatic stress disorder as well as it provides future directions for the field.
Download or read book Immunobiotics Interactions of Beneficial Microbes with the Immune System written by Julio Villena and published by Frontiers Media SA. This book was released on 2018-01-26 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term “immunobiotics” has been proposed to define microbial strains able to beneficially regulate the mucosal immune system. Research in immunobiotics has significantly evolved as researchers employed cutting-edge technologies to investigate the complex interactions of these beneficial microorganisms with the immune system. During the last decade, our understanding of immunobiotics-host interaction was profoundly transformed by the discovery of microbial molecules and host receptors involved in the modulation of gut associated immune system, as well as the systemic and distant mucosal immune systems. In recent years, there has been a substantial increase in the number of reports describing the beneficial effects of immunobiotics in diseases such as intestinal and respiratory infections, allergy, inflammatory bowel disease, obesity, immunosuppression, and several other immune-mediated conditions. Evidence is also emerging of immunobiotics related molecules with immunomodulatory functions leading to the production of pharmabiotics, which may positively influence human or animal health. Therefore, research in immunobiotics continue to contribute not only to food but also medical and pharmaceutical fields. The compilation of research articles included in this ebook should help reader to have an overview of the recent advances in immunobiotics.
