Download or read book Loose Ends from Current Biology written by Sydney Brenner and published by . This book was released on 1997 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Loose Ends false Starts written by Brenner Sydney and published by World Scientific. This book was released on 2019-07-16 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sydney Brenner was born in South Africa and educated at the University of Witwatersrand, Johannesburg (Medicine and Science). He then moved to Oxford and received a D.Phil in 1952, before joining the MRC Unit in the Cavendish Laboratory in Cambridge in 1956. His various accomplishments include serving as the Director of MRC Laboratory of Molecular Biology in Cambridge, founding the Molecular Science Institute in Berkeley, holding the position of Distinguished Professor at the Salk Institute, La Jolla. And during his last years, Sydney Brenner played a key role in shaping research and development in the biomedical sector in Singapore as A*Star Senior Fellow.He was one of the greatest biologists of the 20th century and was awarded the Nobel Prize in 2002 for his pioneering work in the field of molecular biology. He was also known for his boundless curiosity, sharp intellect and courage to speak with clarity and characteristic wit as evident in this delightful book which is a compilation of the columns that he wrote for Current Biology in the late '90s.
Download or read book A Nobel Fellow on Every Floor written by John Finch and published by Icon Books. This book was released on 2024-06-07 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Cambridge in the 1950s, several research groups funded by the Medical Research Council were producing exciting results. In the Biochemistry Department, Sanger determined the amino acid sequence of insulin, and was awarded a Nobel Prize for this in 1958. At the Cavendish Laboratory, in the MRC Unit for the Study of the Molecular Structure of Biological Systems, Watson and Crick solved the structure of DNA, and Perutz and Kendrew produced the first three-dimensional maps of protein structures – haemoglobin and myoglobin – for which all four were later awarded Nobel Prizes. This made it timely to create, in 1962, a new Laboratory of Molecular Biology in Cambridge by amalgamating these groups with other MRC-funded groups from London. The Laboratory has become one of the most successful in its field, and the number of Nobel Prizes awarded over the years to scientists at LMB has risen to thirteen. This book follows the development of LMB, through the people who moved into the new Laboratory and their research. It describes events and personalities that have given the Laboratory a friendly, family atmosphere, while continuing to be scientifically productive.
Download or read book A Life in Science written by Sydney Brenner and published by . This book was released on 2001 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Interpreting Science at Museums and Historic Sites written by Debra A. Reid and published by Rowman & Littlefield. This book was released on 2023 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interpreting Science in Museums and Historic Sites stresses the untapped potential of historical artifacts to inform our understanding of scientific topics. It argues that science gains ground when contextualized in museums and historic sites.
Download or read book The Deeper Genome written by John Parrington and published by Oxford University Press. This book was released on 2017 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mapping the human genome proved to be just the beginning in understanding our genes, what makes us human, and how we can use the knowledge to cure inherited diseases. John Parrington describes an emerging picture of our genome, in 3D, with many non-gene players and environmental influences, that is far more complex and subtle than we ever imagined.
Download or read book Anthony Cerami written by Conrad Keating and published by Rutgers University Press. This book was released on 2021-08-13 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the turn of the new millennium, ‘translational research’, the scientific process of bringing disease-targeted knowledge from the laboratory to treat patients in the clinic, has gone mainstream and is now practiced by large universities and institutes across the globe. Into this dynamic of the rapidly changing world of translational medical research this book sets the life of one of the discipline’s most influential practitioners, Anthony Cerami. His work spans more than five decades and culminated in the discovery, invention and development of diagnostics and therapeutics used daily by millions of people. Students in molecular medicine and investigators pursuing basic science in the hope of improving human health will find inspiration in examining the sacrifices and achievements of Cerami’s career in translational medicine. During his three decades at Rockefeller University his cross-disciplinary and laboratory-without-wall approach established ‘rational drug design’ as the most effective means of advancing the fields of parasitology, hematology, immunology, metabolism, therapeutics and molecular medicine. Cerami’s story and that of the evolution of translation are intimately entwined: the contours of Cerami’s career shaped by developments in translation, and in exchange, the field itself molded by Cerami’s work. To understand one is to understand the other. By examining the life of this often overlooked biochemist it is possible to intimately focus on the ideas and thought processes of a scientist who has helped to define the great acceleration in translational research over the past half century – research that, knowingly or otherwise, has most likely affected the life of almost everyone on the planet. We also gain a better understanding of the febrile creative atmosphere that percolated through the laboratories leading the way in translational medicine, and gain insight into the art, science, successes, failures and providence that underlie major scientific breakthroughs. Anybody interested in the questions of where modern medicines come from, how health outcomes around the globe are affected by research and imagination, and where the future of drug discovery is leading, will be rewarded by exploring Cerami’s life in translation. This book is not restricted to those with a professional interest in science, because anyone dedicated to living a life of creativity and discovery will be rewarded by reading this book. In many respects, Cerami’s life reflects the modern metaphor of the ‘American dream’ with his journey from humble beginnings on a chicken farm in rural New Jersey, to occupying a place in the highest echelons of the US scientific establishment. His journey in translational medicine was propelled forward by two obsessions; the idea that he could help people who were sick, and the excitement of discovery. In following his two great passions, he trained a generation of specialists in translational medicine that continue to transform our understanding of, and treatments for, human disease. Anthony Cerami’s work has shown how science has become an important force for social change by laying the foundations of modern translational medicine.
Download or read book Advances in Microbial Physiology written by Robert K. Poole and published by Academic Press. This book was released on 2021-06-17 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Microbial Physiology, Volume 78, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. This updated release contains the latest information in the field, with comprehensive chapters covering Microbubble Intensification of Bioprocessing, Bacterial cellulose: biosynthesis, production, and applications, Microbial energy management – a product of three broad tradeoffs, and more. - Contains contributions from leading authorities in microbial physiology - Informs and updates on all the latest developments in the field of microbial physiology
Download or read book The Longevity Seekers written by Ted Anton and published by University of Chicago Press. This book was released on 2013-05 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: People have searched for the fountain of youth everywhere from Bimini to St. Augustine. But for a steadfast group of scientists, the secret to a long life lies elsewhere: in the lowly lab worm. By suppressing the function of just a few key genes, these scientists were able to lengthen worms’ lifespans up to tenfold, while also controlling the onset of many of the physical problems that beset old age. As the global population ages, the potential impact of this discovery on society is vast—as is the potential for profit. With The Longevity Seekers, science writer Ted Anton takes readers inside this tale that began with worms and branched out to snare innovative minds from California to Crete, investments from big biotech, and endorsements from TV personalities like Oprah and Dr. Oz. Some of the research was remarkable, such as the discovery of an enzyme in humans that stops cells from aging. And some, like an oft-cited study touting the compound resveratrol, found in red wine—proved highly controversial, igniting a science war over truth, credit, and potential profit. As the pace of discovery accelerated, so too did powerful personal rivalries and public fascination, driven by the hope that a longer, healthier life was right around the corner. Anton has spent years interviewing and working with the scientists at the frontier of longevity science, and this book offers a behind-the-scenes look at the state-of-the-art research and the impact it might have on global public health, society, and even our friends and family. With spectacular science and an unforgettable cast of characters, The Longevity Seekers has all the elements of a great story and sheds light on discoveriesthat could fundamentally reshape human life.
Download or read book Biosemiotics written by Marcello Barbieri and published by Nova Publishers. This book was released on 2007 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents contexts and associations of the semiotic view in biology, by making a short review of the history of the trends and ideas of biosemiotics, or semiotic biology, in parallel with theoretical biology. Biosemiotics can be defined as the science of signs in living systems. A principal and distinctive characteristic of semiotic biology lies in the understanding that in living, entities do not interact like mechanical bodies, but rather as messages, the pieces of text. This means that the whole determinism is of another type.
Download or read book Neural Mechanisms of Cardiovascular Regulation written by Nae J. Dun and published by Springer Science & Business Media. This book was released on 2011-06-27 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Mechanisms of Cardiovascular Regulation responds to current questions about how neurons in the central and peripheral nervous systems regulate the cardiovascular system. It includes a series of thoughtful reviews that are intended to provoke and illuminate the reader, with the intention of revealing some of the ideas that current practitioners in the field of cardiovascular research are using to generate their current studies.
Download or read book Writing Scientific English written by Timothy Skern and published by UTB GmbH. This book was released on 2019-10-07 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Das Verfassen wissenschaftlicher Arbeiten in englischer Sprache ist heute in vielen Studienrichtungen unerlässlich. Gleichzeitig stellt es für Studierende meist eine große Herausforderung dar. Dieses Buch leitet zur richtigen Arbeitsweise und zum korrekten Sprachgebrauch an und schließt damit eine Lücke in der einschlägigen Literatur. Anhand zahlreicher Beispiele werden sowohl gelungene Texte analysiert als auch typische Fehler deutschsprachiger Studierender korrigiert. Success in science depends nowadays on effective communication in English. This workbook is specifically designed to give under- and post-graduates confidence in writing scientific English. Examples and exercises show how to avoid common errors and how to rephrase and improve scientific texts. The generation of a model manuscript enables the reader to recognise how scientific English is constructed and how to follow the conventions of scientific writing. Guidelines for structuring written work and vocabulary lists will encourage young scientists to develop a concise and mature style. The workbook is accessible to students of many fields, including those of the natural and technical sciences, medicine, psychology and economics.
Download or read book Technological and Medical Implications of Metabolic Control Analysis written by Athel Cornish-Bowden and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two decades have passed since the mechanisms of protein synthesis became well enough understood to permit the genetic modification oforganisms. An impressive amount of new knowledge has emerged from the new technology, but much ofthe promise of20years ago has notyet been fulfilled. In biotechnology, efforts to increase the yields of commercially valuable metabolites have been less successful than ex pected, and when they have succeeded it has often been as much from selective breeding as from new methods. The cell is more complicated than what is presented in the classical teaching of biochemistry, it contains more structure than was dreamed of 20 years ago, and the behaviour ofany systemofenzymes is more elaborate than can be explained in terms ofa single supposedly rate-limiting enzyme. Even if classical enzymology and meta bolism may have seemed rather unfashionable during the rise ofmolecular biology, they remain central to any modification ofthe metabolic behaviour oforganisms. As such modification is essential in much ofbiotechnology and drug development, bio technologists can only ignore these topics at their peril.
Download or read book Reflections on language evolution written by Cedric Boeckx and published by Language Science Press. This book was released on with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essay reflects on the fact that as we learn more about the biological underpinnings of our language faculty, the dominant evolutionary narrative coming out of the linguistic tradition most explicitly oriented towards biology ("biolinguistics") appears increasingly implausible. This text offers ways of opening up linguistic inquiry and fostering interdisciplinarity, taking advantage of new opportunities to provide quantitative, testable hypotheses concerning the complex evolutionary path that led to the modern human language faculty. The essay is structured around three main themes: (i) renewed appreciation for the comparative method applied to cognitive questions, leading to the identification of elementary but fundamental abstractions in non-linguistic species relevant to language; (ii) awareness of the conceptual gaps between disciplines, and the need to carefully link genotype and phenotype without bypassing any "intermediate" levels of description (certainly not the brain); and (iii) adoption of a "philosophical" outlook that puts the complexity of biological entities front and center.
Download or read book Cracking the Genome written by Kevin Davies and published by JHU Press. This book was released on 2002-10 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This newly updated edition sheds light on the secrets of the sequence, highlighting the myriad ways in which genomics will impact human health for generations to come.
Download or read book Nature s Gift to Neuroscience written by Chun-Fang Wu and published by CRC Press. This book was released on 2022-02-27 with total page 839 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the 1960s, Sydney Brenner proposed to use the nematode worm Caenorhabditis elegans to discover the control mechanisms of animal development and to reveal how a small number of neurons generate different behaviours, giving birth to a vibrant community that uses this animal model for their studies. Brenner was aided in his aim by John Sulston, who mapped the C. elegans cell lineages – from a single cell to the multicellular adult – which transformed the field of developmental biology. As a tribute to these two men, this book captures the perspectives of some of the early pioneers of the worm community, from Martin Chalfie, Robert Waterston and Donald Moerman to Catherine Rankin, Antony Stretton and John White. It also includes contributions from subsequent generations of the community, who explore the development and function of the C. elegans nervous system. This book features how this animal has become one of the best models for elucidating the biology of different sensory modalities and their complex behavioural outputs, or how this animal’s survival strategies have contributed to our understanding of ageing and neurodegeneration. Thus, this volume documents the development of the C. elegans neuroscience field, from infancy to maturity. The chapters in this book were originally published as a special issue of the Journal of Neurogenetics.
Download or read book The Vital Question written by Nick Lane and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A game-changing book on the origins of life, called the most important scientific discovery 'since the Copernican revolution' in The Observer.
