Download or read book Looking Forward to the Future of Heparin New Sources Developments and Applications written by Giangiacomo Torri and published by . This book was released on 2018 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Looking Forward to the Future of Heparin: New Sources, Developments and Applications.
Download or read book Looking Forward to the Future of Heparin written by and published by Mdpi AG. This book was released on 2018-06-12 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The year of 2016 marks the centenary celebration of the discovery of heparin, a very complex and heterogeneous macromolecule used as a lifesaving drug. Approaching the centenary, many meetings occurred. These events actualize, in addition to the historical aspects, the research themes of current interest. This Special Issue, devoted to heparin, aims to provide interdisciplinary information regarding such research by combining aspects of chemical structures to those of biological activity and collating contributions on the following issues. One of the currently relevant issues is the pharmaco-biological activities of heparins depleted of anticoagulant activity, involving research ranging from antitumor to antiviral applications. The technological processes to obtain synthetic heparins, or oligomers with defined structures, represent another current area of research, as well as heparin as part of nanostructured systems. Following renewed interest by industrial and social committees on the alternative sources of swine heparin, there is a great deal of research focused on the structural peculiarities and pharmaco-biological activities of heparin extracted from bovine tissues, which is being assessed by the FDA for inclusion in Pharmacopoeia. Similarly sheep sources are of particular interest for Asian countries.
Download or read book Iron Metabolism Hepcidin written by Gerald Litwack and published by Academic Press. This book was released on 2019-02-22 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron Metabolism, Volume 110, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more. - Focuses on the newest aspects of hormone action in connection with diseases - Lays the groundwork for the focus of new chemotherapeutic targets - Represents reviews on emerging areas in hormone action, cellular regulators and signaling pathways
Download or read book Heparin Present and Future written by G. G. Neri Serneri and published by S. Karger AG (Switzerland). This book was released on 1990 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Heparin A Century of Progress written by Rebecca Lever and published by Springer Science & Business Media. This book was released on 2012-05-08 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.
Download or read book Textbook of Coronary Thrombosis and Thrombolysis written by R. C. Becker and published by Springer Science & Business Media. This book was released on 2008-01-21 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teleologically, the hemostatic mechanism is among The of Coronary Thrombosis and the most fundamental yet complex physiologic pro- in essence, represents a heartfelt gift of cesses in humans. Early scientists and physicians were knowledge from a dedicated group of scientists and fascinated by the blood's ability to remain in a liquid clinicians, who collectively have set out on a mission state only to clot in response to vascular injury. The to minimize the societal impact of"hemostasis in the cellular and noncellular components of normal wrong place. " The book is divided into four distinct hemostasis took centuries to discover, and the intrica- sections: Part 1, Scientific Principles, lays down the cies of their delicate interactions are still being unrav- supporting foundation; Part 2, Clinical Application eled today. As is so often the case, an in-depth of Scientific Principles, places the knowledge base in appreciation of physiologic hemostasis, representing a a working perspective, directly applying science to basic life-sustaining sequence of events, paved the patient care; Part 3, New Dimensions, provides a way for understanding abnormal hemostasis or glimpse of tomorrow. Steering the field clear of se- pathologic thrombosis. Aristotle, Malpighi, and proclaimed victory and the dangers of complacency as Osier, representing but a few of the founding fathers we move into the 21st century, Part 4, Evolution of in the field, would undoubtedly be honored to see Thrombocardiology, focuses on laboratory standards, their observations form the template for lifesaving clinical trials, and drugs in development.
Download or read book Acute Pulmonary Embolism written by A. Geibel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- New developments in the thrombolytic therapy of venous thrombosis.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.MR-angiography in the diagnosis of pulmonary embolism.Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- Clinical course and prognosis of acute pulmonary embolism.- The molecular mechanisms of inherited thombophilia.
Download or read book Discussion Draft of the Food and Drug Administration Globalization Act Legislation Device and Cosmetic Safety Provisions Serial No 110 117 May 14 2008 110 2 Hearing written by and published by . This book was released on 2010 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Discussion Draft of the Food and Drug Administration Globalization Act Legislation written by United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Health and published by . This book was released on 2008 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Chemistry of Blood Coagulation written by Paul Morawitz and published by . This book was released on 1958 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Catheter Ablation of Atrial Fibrillation written by Etienne Aliot and published by John Wiley & Sons. This book was released on 2011-08-31 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Catheter Ablation of Atrial Fibrillation Edited by Etienne Aliot, MD, FESC, FACC, FHRS Chief of Cardiology, Hôpital Central, University of Nancy, France Michel Haïssaguerre, MD Chief of Electrophysiology, Hôpital Cardiologique du Haut-Lévêque, France Warren M. Jackman, MD Chief of Electrophysiology, University of Oklahoma Health Science Center, USA In this text, internationally recognized authors explore and explain the advances in basic and clinical electrophysiology that have had the greatest impact on catheter ablation of atrial fibrillation (AF). Designed to assist in patient care, stimulate research projects, and continue the remarkable advances in catheter ablation of AF, the book covers: the fundamental concepts of AF, origin of signals, computer simulation, and updated reviews of ablation tools the present practical approaches to the ablation of specific targets in the fibrillating atria, including pulmonary veins, atrial neural network, fragmented electrograms, and linear lesions, as well as the strategies in paroxysmal or chronic AF or facing left atrial tachycardias the special challenge of heart failure patients, the impact of ablation on mortality, atrial mechanical function, and lessons from surgical AF ablation Richly illustrated by numerous high-quality images, Catheter Ablation of Atrial Fibrillation will help every member of the patient care team.
Download or read book Examining the Impact of Real World Evidence on Medical Product Development written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-04-05 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Randomized controlled trials (RCTs) have traditionally served as the gold standard for generating evidence about medical interventions. However, RCTs have inherent limitations and may not reflect the use of medical products in the real world. Additionally, RCTs are expensive, time consuming, and cannot answer all questions about a product or intervention. Evidence generated from real-world use, such as real-world evidence (RWE) may provide valuable information, alongside RCTs, to inform medical product decision making. To explore the potential for using RWE in medical product decision making, the National Academies of Sciences, Engineering, and Medicine planned a three-part workshop series. The series was designed to examine the current system of evidence generation and its limitations, to identify when and why RWE may be an appropriate type of evidence on which to base decisions, to learn from successful initiatives that have incorporated RWE, and to describe barriers that prevent RWE from being used to its full potential. This publication summarizes the discussions from the entire workshop series.
Download or read book Pediatric Pharmacology and Drug Therapy An Issue of Pediatric Clinics of North America E Book written by Jacob V. Aranda and published by Elsevier Health Sciences. This book was released on 2017-12-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Aranda is an top expert in the area of pharmacology in the pediatric population. His issue has knowledgeable authors presenting clinical reviews on a wide variety of topics, from "hot areas " of drug therapy to drug abuse in children as well as current areas of debate in neonatal drug therapy. Articles are devoted to the following topics: New and Current Drug Therapies For Asthma In Children; Psychopharmacology Of Bipolar Disorders in Children and Adolescents; Designer Drug Abuse in School Children; Dietary Supplements in Children; Anticoagulant Therapies in Children; New Antimicrobials for Gram-Positive Infections in Children; Probiotics in Newborns And Children; Anticonvulsant Therapies in Newborns and Children; Immunomodulator Drug Therapies in Inflammatory Bowel Diseases in Children; Non-Steroidal Anti-Inflammatory Drugs in Newborns and Children; Metformin Use in Pre-Diabetic Children and Adolescents; Problems in Drug Dosing of Obese Children; Inhaled Drugs and Systemic Steroids for Bronchopulmonary Dysplasia; Antifungal Drugs in Newborns and Children; Antiviral Drugs In Newborns and Children; and Development of Drug Therapies for Newborns and Children. Readers will come away with the latest clinical information to help inform them when diagnosing and prescribing for children.
Download or read book Vascular Access Catheter Materials and Evolution written by Joseph D. Giusto and published by Xlibris Corporation. This book was released on 2014-06-24 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief, yet interesting, history gives insight to the ancient materials and devices first applied to bodily drainage catheters and its leading to modern materials and modern vascular access systems. The latter are currently performing as feeding tubes, drug delivery and blood sampling, some directly into the heart, especially as used in the field of oncology. Elastomeric materials, natural and synthetic and flexible plastics, polyurethanes, polyethylene, polyvinylchloride, Teflon, and Nylon, all have been studied for vascular catheters. This scientific article also describes the clinical investigations by early leaders in this field, whose courage goes far beyond belief, some actually using their own bodies for experimentation.
Download or read book Heart Lung written by and published by . This book was released on 1986-07 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Until Death Do You Part A Story of Faith Hope and Love written by Jeff Coulter and published by JNS Ministries. This book was released on 2022-01-22 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a story written from two different perspectives: one of a husband and one of a wife. Our individual lives started from two diverse worlds and combined to become one life in 1987. We considered ourselves the typical, normal suburban family. As we grew in our marriage and focused on raising our children, we were determined to do so with God in first place and the kids in church. Unfortunately, the circumstances of life came into play a few years into our marriage and developed into a near cataclysmic end to two wonderful relationships: Our marriage to each other and our marriage to Christ. Jeff and Suzanne Coulter have been married since 1987. Jeff Coulter was born in 1966 and is from Williamsburg, Ohio. A devout Christian throughout his early adulthood, Jeff reached a crossroad with the death of his mother in 1988 and found himself turning away from God. On April 22nd, 2014 Jeff was nearly killed in a head on collision. Beating the odds and surviving the crash, one week later Jeff suffered multiple pulmonary emboli. Only 1 out of 20 survive such a traumatic incident. Jeff slipped into a void of nothingness; the absolute absence of the presence of God. A void filled with demonic beings and symbolic icons of hell and death. Miraculously surviving the crash and emboli, God also delivered Jeff from alcoholism and chronic depression. Through it all there was his wife Suzanne at his side as if she belonged there by God’s own invitation. Driving him along the way. Jeff has since rededicated his life to Christ and now dedicates himself to church ministries, online ministries and authoring diverse books.
Download or read book Operative Techniques in Liver Resection written by Lunan Yan and published by Springer. This book was released on 2015-12-22 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest knowledge in liver resection. It includes preoperative assessment, hepatic vascular occlusion, live parenchyma transection, various liver resection techniques, liver transplantation, ex situ ex vivo resection, auto-transplantation, laparoscopic liver resection and outcome of liver resection. It describes 21 resection techniques in the same style. Each chapter is built around a series of descriptive photographs and illustrations, which are explained in detail in the text. At the end of each section there are key points that are critical for surgeons performing liver resections. The authors share their extensive experience of liver resections. This book will help practitioners perform safe and expeditious resections and reduce postoperative liver failure. Hepato-bilio pancreatic surgeons, hepatologists, radiologists, clinicians and researchers who are interested in liver surgery will find this book an invaluable guide.
