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Book Long term Effects of Multimodal Treatment on Adult Attention deficit hyperactivity Disorder Symptoms  Follow up Analysis of the COMPAS Trial

Download or read book Long term Effects of Multimodal Treatment on Adult Attention deficit hyperactivity Disorder Symptoms Follow up Analysis of the COMPAS Trial written by Alexandra P. Lam and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Importance Knowledge about the long-term effects of multimodal treatment in adult attention-deficit/hyperactivity disorder (ADHD) is much needed. Objective To evaluate the long-term efficacy of multimodal treatment for adult ADHD. Design, Setting, and Participants This observer-masked, 1.5-year follow-up of the Comparison of Methylphenidate and Psychotherapy in Adult ADHD Study (COMPAS), a prospective, multicenter randomized clinical trial, compared cognitive behavioral group psychotherapy (GPT) with individual clinical management (CM) and methylphenidate (MPH) with placebo (2 × 2 factorial design). Recruitment started January 2007 and ended August 2010, and treatments were finalized in August 2011 with follow-up through March 2013. Overall, 433 adults with ADHD participated in the trial, and 256 (59.1%) participated in the follow-up assessment. Analysis began in November 2013 and was completed in February 2018. Interventions After 1-year treatment with GPT or CM and MPH or placebo, no further treatment restrictions were imposed. Main Outcomes and Measures The primary outcome was change in the observer-masked ADHD Index of Conners Adult ADHD Rating Scale score from baseline to follow-up. Secondary outcomes included further ADHD rating scale scores, observer-masked ratings of the Clinical Global Impression scale, and self-ratings of depression on the Beck Depression Inventory. Results At follow-up, 256 of 433 randomized patients (baseline measured in 419 individuals) participated. Of the 256 patients participating in follow-up, the observer-masked ADHD Index of Conners Adult ADHD Rating Scale score was assessed for 251; the mean (SD) baseline age was 36.3 (10.1) years; 125 patients (49.8%) were men; and the sample was well-balanced with respect to prior randomization (GPT and MPH: 64 of 107; GPT and placebo: 67 of 109; CM and MPH: 70 of 110; and CM and placebo: 55 of 107). At baseline, the all-group mean ADHD Index of Conners Adult ADHD Rating Scale score was 20.6, which improved to adjusted means of 14.2 for the GPT arm and 14.7 for the CM arm at follow-up with no significant difference between groups (difference, −0.5; 95% CI, −1.9 to 0.9; P = .48). The adjusted mean decreased to 13.8 for the MPH arm and 15.2 for the placebo arm (difference, −1.4; 95% CI, −2.8 to −0.1; P = .04). As in the core study, MPH was associated with a larger reduction in symptoms than placebo at follow-up. These results remained unchanged when accounting for MPH intake at follow-up. Compared with participants in the CM arm, patients who participated in group psychotherapy were associated with less severe symptoms as measured by the self-reported ADHD Symptoms Total Score according to the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) (DSM-IV) of Conners Adult ADHD Rating Scale (AMD, −2.1; 95% CI, −4.2 to −0.1; P = .04) and in the subscale of reducing pure hyperactive symptoms, measured via the Diagnostic Checklist for the diagnosis of ADHD in adults (AMD, −1.3; 95% CI, −2.8 to 0.1; P = .08). Regarding the Clinical Global Impression scale assessment of effectiveness, the difference between GPT and CM remained significant at follow-up (odds ratio, 1.63; 95% CI, 1.03-2.59; P = .04). No differences were found for any comparison concerning depression as measured with the Beck Depression Inventory. Conclusions and Relevance Results from COMPAS demonstrate a maintained improvement in ADHD symptoms for adults 1.5 years after the end of a 52-week controlled multimodal treatment period. The results indicate that MPH treatment combined with GPT or CM provides a benefit lasting 1.5 years. Confirming the results of the core study, GPT was not associated with better results regarding the primary outcome compared with CM. Trial Registration isrctn.org Identifier: ISRCTN54096201

Book How to Thrive with Adult ADHD

Download or read book How to Thrive with Adult ADHD written by James Kustow and published by Random House. This book was released on 2024-10-03 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: '‘Affirming, validating and life-enhancing – if you think you may have ADHD, this book is for you’ – Matt Willis, musician and podcaster Don’t just manage your ADHD – thrive with it If you have, or suspect you have, ADHD, or you simply feel stuck – drowning in half-finished tasks, unhelpful habits and a perpetual feeling that you can’t seem to ‘get it together’ – then this book is for you. As a leading adult ADHD psychiatrist, who himself has ADHD, Dr James Kustow passionately believes that the goal should not be to just ‘manage’ ADHD, but to thrive with it. This ground-breaking book will allow you to assess if and how the condition affects you, mapping your unique ‘ADHD signature’, before leading you through a seven-pillar plan of small but powerful habit changes. You will learn: How to stabilise your sleep, schedule and surroundings, so you can direct energy to the things that really matter. Easy-to-implement strategies and tools to streamline your life. Simple techniques to calm your mind, reduce the ‘noise’ and achieve your goals, underpinned by a growth-oriented mindset. Practical ways to optimise your nutrition and reduce toxic exposures, to improve brain health. In small, manageable steps, you can transform the chaos into focus, productivity and balance – for life.

Book Attention Deficit Hyperactivity Disorder  ADHD  in Adults

Download or read book Attention Deficit Hyperactivity Disorder ADHD in Adults written by Wolfgang Retz and published by Karger Medical and Scientific Publishers. This book was released on 2010 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Worldwide longitudinal studies performed since the 1970s have clearly shown that ADHD persists into adulthood. These findings have stimulated researchers to develop the therapeutic approaches for adult patients, especially in European countries where scientific and clinical interest in ADHD has increased.. In this volume, leading experts from Europe and the United States present their long-term results in order to provide an overview of important aspects of ADHD across the lifespan. These results include epidemiology, neurobiology, psychopathology, longitudinal course, comorbidity and social impairment associated with ADHD. Topics include diagnostic problems and therapeutic options as well as molecular genetic studies. Further, morphological and functional imaging studies in adult ADHD are reviewed, as well as the very important issue of comorbidity. Providing an excellent source of up-to-date information, this publication is essential reading for psychiatrists, neurologists, geneticists, psychotherapists, physicians and other therapists working with ADHD patients.

Book Mental Health Considerations in the Athlete  An Issue of Clinics in Sports Medicine  E Book

Download or read book Mental Health Considerations in the Athlete An Issue of Clinics in Sports Medicine E Book written by Siobhan M. Statuta and published by Elsevier Health Sciences. This book was released on 2023-11-14 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Clinics in Sports Medicine, guest editor Dr. Siobhán M. Statuta brings her considerable expertise to the topic of Mental Health Considerations in the Athlete. Many athletes struggle with mental health symptoms and disorders, and often do not openly speak of this due to the stigma surrounding mental health, as well as fear of consequences if others were to be made aware. Mental wellbeing, as a critical component of overall health, is an area that is imperative to assess, screen, and treat to allow athletes to live overall fruitful lives. - Contains 13 relevant, practice-oriented topics including a review of media representation of sport concussion and implications for youth sports; anxiety disorders in athletes; depressive disorders in athletes; mental health and eating disorders/disordered eating; identification and management of substance misuse in elite athletes; (social) media and mental health; and more. - Provides in-depth clinical reviews on mental health considerations in the athlete, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Book Age adjusted Psychiatric Treatment for the Older Patient

Download or read book Age adjusted Psychiatric Treatment for the Older Patient written by Howard H. Fenn and published by Springer Nature. This book was released on 2024 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers practical age-adjusted recommendations to treat the most common psychiatric symptoms and syndromes in the geriatric patient. The principles described here are not new; advice for prescribing to the aging patient has always been to "start low, go slow." This book fleshes out that dictum based on research evidence, clinical experience, and trends in the literature. An age-adjusted approach endorses medication interventions when needed as part of a comprehensive treatment plan. A combination of psychotherapeutic interventions, non-pharmacological modalities, and judiciously managed medications can improve quality of life and minimize risks inherent in pharmacotherapy applied to aging physiology. Age-Adjusted Psychiatric Treatment for the Older Patient is divided into five sections, covering the foundations of evaluation and treatment, neurocognitive disorders, psychiatric syndromes, therapeutics and interventions, and special topics. Each chapter begins with a complex case example that illustrates the topic. It then reviews current evidence-based evaluation and treatments. Age-adjusted recommendations, distilled from the literature, are offered at the end of each chapter. The intent is to provide actionable advice to supplement, but not supplant, good clinical judgement, which can improve quality of life by managing psychiatric symptomatology while averting untoward results. This volume is an essential guide for experienced clinicians as well as trainees across many health care disciplines, both generalists and geriatric specialists, who all see increasing numbers of aged patients with psychiatric symptomatology.

Book Global Health and Pharmacology

Download or read book Global Health and Pharmacology written by Susan Leigh Craddock and published by Frontiers Media SA. This book was released on 2021-12-06 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Attention Deficit Hyperactivity Disorder

Download or read book Attention Deficit Hyperactivity Disorder written by National Collaborating Centre for Mental Health (Great Britain) and published by Royal College of Psychiatrists. This book was released on 2009 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title sets out clear recommendations for healthcare staff, based on the best available evidence, on how to diagnose and manage both children and adults who have ADHD to significantly improve their treatment and care.

Book Adult ADHD

    Book Details:
  • Author : J.J. Sandra Kooij
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-11
  • ISBN : 1447141385
  • Pages : 304 pages

Download or read book Adult ADHD written by J.J. Sandra Kooij and published by Springer Science & Business Media. This book was released on 2012-12-11 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adult ADHD: Diagnostic Assessment and Treatment, Third Edition covers not only diagnostic assessment, but also comorbidity patterns as well as differential diagnosis of ADHD with for example bipolar disorder and borderline personality disorder. The symptom overlap and misdiagnosis of chronic fatigue syndrome in girls and women with the inattentive subtype of ADHD, ADD is explored. The chronic delayed sleep phase syndrome associated with ADHD based on disturbances in the circadian rhythm, and the possible consequences for general health (obesity, diabetes, cardiovascular diseases and cancer) are discussed. There are sections on ADHD and intelligence, criminality, sexuality, dyslexia and autism. Adult ADHD can be treated effectively but as yet the disorder is not always recognised by professionals and this book aims to help correct this. Diagnostic tools are included, such as the structured Diagnostic Interview for Adult ADHD (DIVA), and an ultra-short and somewhat longer screening tool, all based on the DSM-IV criteria for ADHD. Treatment options cover psychoeducation and motivation and individual and group coaching; long-acting stimulants and other new drugs for treating ADHD; use of melatonin to treat the delayed sleep-phase disorder. Useful information is included on the setting up and organisation of a department for adult ADHD with a multidisciplinary team. References, websites and useful international addresses have all been updated. Adult ADHD: Diagnostic Assessment and Treatment, Third Edition is intended for students, junior doctors/residents, psychologists, psychiatrists, other mental healthcare professionals and interested parties and provides a quick overview of the current state of the science and of the methods used in diagnosis and treatment. Adult ADHD: Diagnostic Assessment and Treatment, Third Edition was originally published by Pearson Assessment and Information BV, The Netherlands.

Book Cognitive Behavioral Therapy for Adult ADHD

Download or read book Cognitive Behavioral Therapy for Adult ADHD written by J. Russell Ramsay and published by Routledge. This book was released on 2014-09-25 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cognitive Behavioral Therapy for Adult ADHD: An Integrative Psychosocial and Medical Approach has been revised, updated, and expanded for this second edition and remains the definitive book for clinicians seeking to treat adults with ADHD. Clinicians will continue to benefit from the presentation of an evidence-supported treatment approach for adults with ADHD that combines cognitive behavioral therapy and pharmacotherapy adapted for this challenging clinical population. The updated edition of the book offers new and expanded case examples, and the authors emphasize more detailed, clinician-friendly "how to" instructions for the delivery of specific interventions for adult patients with ADHD. Understanding that most adults with ADHD say, "I know exactly what I need to do, but I just cannot make myself do it," the book pays special attention to the use of implementation strategies to help patients carry out the necessary coping skills to achieve improvements in functioning and well-being in their daily lives. In addition to providing an outline of their treatment approach, Drs. Ramsay and Rostain provide an up-to-date review of the current scientific understanding of the etiology, developmental course, and life outcomes of adults with ADHD as well as the components of an thorough diagnostic evaluation. As an added clinical resource, Drs. Ramsay and Rostain have also produced a companion patient handbook written for adults with ADHD, The Adult ADHD Tool Kit: Using CBT to Facilitate Coping Inside and Out, which clinicians can use with their patients.

Book Reducing Risks for Mental Disorders

Download or read book Reducing Risks for Mental Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 1994-01-01 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of how to reduce risk factors for mental disorders has expanded remarkably as a result of recent scientific advances. This study, mandated by Congress, reviews those advances in the context of current research and provides a targeted definition of prevention and a conceptual framework that emphasizes risk reduction. Highlighting opportunities for and barriers to interventions, the book draws on successful models for the prevention of cardiovascular disease, injuries, and smoking. In addition, it reviews the risk factors associated with Alzheimer's disease, schizophrenia, alcohol abuse and dependence, depressive disorders, and conduct disorders and evaluates current illustrative prevention programs. The models and examination provide a framework for the design, application, and evaluation of interventions intended to prevent mental disorders and the transfer of knowledge about prevention from research to clinical practice. The book presents a focused research agenda, with recommendations on how to develop effective intervention programs, create a cadre of prevention researchers, and improve coordination among federal agencies.

Book Gabbard s Treatments of Psychiatric Disorders

Download or read book Gabbard s Treatments of Psychiatric Disorders written by Glen O. Gabbard and published by American Psychiatric Pub. This book was released on 2014-05-05 with total page 1250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive treatment textbook in psychiatry, this fifth edition of Gabbard's Treatments of Psychiatric Disorders has been thoroughly restructured to reflect the new DSM-5® categories, preserving its value as a state-of-the-art resource and increasing its utility in the field. The editors have produced a volume that is both comprehensive and concise, meeting the needs of clinicians who prefer a single, user-friendly volume. In the service of brevity, the book focuses on treatment over diagnostic considerations, and addresses both empirically-validated treatments and accumulated clinical wisdom where research is lacking. Noteworthy features include the following: Content is organized according to DSM-5® categories to make for rapid retrieval of relevant treatment information for the busy clinician. Outcome studies and expert opinion are presented in an accessible way to help the clinician know what treatment to use for which disorder, and how to tailor the treatment to the patient. Content is restricted to the major psychiatric conditions seen in clinical practice while leaving out less common conditions and those that have limited outcome research related to the disorder, resulting in a more streamlined and affordable text. Chapters are meticulously referenced and include dozens of tables, figures, and other illustrative features that enhance comprehension and recall. An authoritative resource for psychiatrists, psychologists, and psychiatric nurses, and an outstanding reference for students in the mental health professions, Gabbard's Treatments of Psychiatric Disorders, Fifth Edition, will prove indispensable to clinicians seeking to provide excellent care while transitioning to a DSM-5® world.

Book Childhood Cancer and Functional Impacts Across the Care Continuum

Download or read book Childhood Cancer and Functional Impacts Across the Care Continuum written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-09-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.

Book Handbook of Adolescent Health Risk Behavior

Download or read book Handbook of Adolescent Health Risk Behavior written by Ralph J. DiClemente and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adolescence is a developmental period of accelerating physical, psychological, social! cultural, and cognitive development, often characterized by confronting and surmounting a myriad of challenges and establishing a sense of self-identity and autonomy. It is also, unfortunately, a period fraught with many threats to the health and well-being of adoles cents and with substantial consequent impairment and disability. Many of the adverse health consequences experienced by adolescents are, to a large extent, the result of their risk behaviors. Many adolescents today, and perhaps an increasing number in the future, are at risk for death, disease, and other adverse health outcomes that are not primarily biomedical in origin. In general, there has been a marked change in the causes of morbidity and mortality among adolescents. Previously, infectious diseases accounted for a dispro portionate share of adolescent morbidity and mortality. At present, however, the over whelming toll of adolescent morbidity and mortality is the result of lifestyle practices.

Book The Oxford Handbook of Clinical Psychology

Download or read book The Oxford Handbook of Clinical Psychology written by David H. Barlow and published by Oxford University Press, USA. This book was released on 2014 with total page 977 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Handbook of Clinical Psychology synthesizes a half-century of clinical psychology literature in one extraordinary volume. Comprising chapters from the foremost scholars in the field, this handbook provides even and authoritative coverage of the research, practice, and policy factors that combine to form today's clinical psychology landscape. It is a landmark publication that is sure to serve as the field's benchmark reference publication for years to come.

Book Innate

    Book Details:
  • Author : Kevin J. Mitchell
  • Publisher : Princeton University Press
  • Release : 2020-03-31
  • ISBN : 0691204152
  • Pages : 305 pages

Download or read book Innate written by Kevin J. Mitchell and published by Princeton University Press. This book was released on 2020-03-31 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: "What makes you the way you are--and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive the world. We all share a genetic program for making a human brain, and the program for making a brain like yours is specifically encoded in your DNA. But, as Mitchell explains, the way that program plays out is affected by random processes of development that manifest uniquely in each person, even identical twins. The key insight of Innate is that the combination of these developmental and genetic variations creates innate differences in how our brains are wired--differences that impact all aspects of our psychology--and this insight promises to transform the way we see the interplay of nature and nurture. Innate also explores the genetic and neural underpinnings of disorders such as autism, schizophrenia, and epilepsy, and how our understanding of these conditions is being revolutionized. In addition, the book examines the social and ethical implications of these ideas and of new technologies that may soon offer the means to predict or manipulate human traits. Compelling and original, Innate will change the way you think about why and how we are who we are."--Provided by the publisher.

Book Neural Circuitry of Behavioral Flexibility  Dopamine and Related Systems

Download or read book Neural Circuitry of Behavioral Flexibility Dopamine and Related Systems written by Gregory B. Bissonette and published by Frontiers Media SA. This book was released on 2016-03-22 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Decades of research have identified a role for dopamine neurotransmission in prefrontal cortical function and flexible cognition. Abnormal dopamine neurotransmission underlies many cases of cognitive dysfunction. New techniques using optogenetics have allowed for ever more precise functional segregation of areas within the prefrontal cortex, which underlie separate cognitive functions. Learning theory predictions have provided a very useful framework for interpreting the neural activity of dopamine neurons, yet even dopamine neurons present a range of responses, from salience to prediction error signaling. The functions of areas like the Lateral Habenula have been recently described, and its role, presumed to be substantial, is largely unknown. Many other neural systems interact with the dopamine system, like cortical GABAergic interneurons, making it critical to understand those systems and their interactions with dopamine in order to fully appreciate dopamine•s role in flexible behavior. Advances in human clinical research, like exome sequencing, are driving experimental hypotheses which will lead to fruitful new research directions, but how do (or should?) these clinical findings inform basic research? Following new information from these techniques, we may begin to develop a fresh understanding of human disease states which will inform novel treatment possibilities. However, we need an operational framework with which to interpret these new findings. Therefore, the purpose of this Research Topic is to integrate what we know of dopamine, the prefrontal cortex and flexible behavior into a clear framework, which will illuminate clear, testable directions for future research.

Book Theories on Drug Abuse

    Book Details:
  • Author : National Institute on Drug Abuse. Division of Research
  • Publisher :
  • Release : 1980
  • ISBN :
  • Pages : 534 pages

Download or read book Theories on Drug Abuse written by National Institute on Drug Abuse. Division of Research and published by . This book was released on 1980 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: