Download or read book Life Threatening Coagulation Disorders in Critical Care Medicine written by Viola Hach-Wunderle and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypercoagulability and bleeding are problems physicians frequently encounter when treating intensive care patients. The coagulation mechanism is a tightly controlled system. Its balance is disturbed in conditions such as septicemia, trauma, shock, and others. The dis turbances may be local or disseminated and the therapeutic options available are limited and nonspecific: limited since in most cir cumstances they may not affect the underlying disease and are si milarly independent of the pathogenic mechanism; nonspecific since they cannot be specifically targeted to the problem of local or sys temic disturbance of coagulation. Furthermore, increased and de creased coagulability may be present at the same time. Activation of coagulation may lead to fibrin deposition and decreased hemostatic capacity, as seen in disseminated intravascular coagulation. New diagnostic approaches for acquired disorders of coagulation have been developed and form a new basis for therapeutic strategies. Despite this progress, many physicians are aware of the problem that, especially for intensive care patients, a treatment very often has to be selected before diagnostic procedures can be completed. We also know that for many diseases rare occurrence or the hetero genity of the patient population make it quite difficult to conduct clinical studies which prove that a therapeutic regimen is efficacious. Thus, much discussion about coagulation disorders in critically ill patients is still necessary. Even so, it is important to provide guidelines for handling these problems.
Download or read book Hemocoagulative Problems in the Critically Ill Patient written by Giorgio Berlot and published by Springer Science & Business Media. This book was released on 2012-04-05 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the very beginning of critical care medicine, much attention has been paid to the risk of bleeding, but only recently the risk of thrombosis has been recognized in critical patients; in fact, current laboratory investigations aimed to monitor blood coagulation are more focused on the assessment of the hemorrhagic than of the thrombotic risk. Since mid-90s, many studies have detected powerful pro-thrombotic actions of endogenous mediators in sepsis and other inflammatory conditions, including trauma and postoperative status. Unfortunately, the related complication are both hard to detect and extremely harmful. The volume provides a full coverage of the hemocoagulative problems in anesthesia and intensive care, taking into consideration the physiology and monitoring of hemostasis, its relation with sepsis, and the specific aspects of the various critical conditions - from trauma to burns, to heart and transplant surgery or acute renal failure.
Download or read book Trauma Induced Coagulopathy written by Hunter B. Moore and published by Springer Nature. This book was released on 2020-10-12 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.
Download or read book Coagulation Endothelial Dysfunction An Issue of Critical Care Clinics written by Hernando Gomez and published by Elsevier Health Sciences. This book was released on 2020-03-19 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Critical Care Clinics, guest edited by Drs. Hernando Gomez Danies and Joseph Carcillo, focuses on Coagulation/Endothelial Dysfunction. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Cell-cell communication breakdown and endothelial dysfunction; Role of the Tie2/Angiopoetin pathway in endothelial dysfunction; The Glycocalyx; Platelet activation and endothelial dysfunction; Role of antithrombin III and tissue factor pathway; Red blood cell dysfunction; Microvascular hemodynamics, autoregulation and mechanotransduction control of blood flow distribution; Nitric oxide and endothelial dysfunction; Microvascular dysfunction; Hemolytic Uremic Syndrome and atypical HUS; Thrombotic thrombocytopenic purpura, Heparin induced thrombocytopenia and Disseminated intravascular coagulation in the critically ill; Thrombocytopenia associated multiple organ failure (TAMOF); Meningococcemia; Immune consequences of endothelial dysfunction during sepsis; Therapeutic targets in thrombotic microangiopathies with a focus on endothelial disorders; and Coagulation disorders in HLH/Macrophage activation syndrome.
Download or read book Handbook of ICU Therapy written by Ian McConachie and published by Cambridge University Press. This book was released on 2006-01-12 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of ICU Therapy provides rapid access to important information on the treatment of the critically ill patient. It comprises a series of 'cutting edge' reviews of the most advanced treatment concepts available in the modern ICU. Whilst assuming a basic knowledge of underlying conditions, it nonetheless outlines key physiological principles where necessary, and critically reviews current literature and best practice. The heart of the book is aimed at providing key practical information on treatment techniques to the busy clinician in an easily accessible style. In addition to conventional drug therapy, ventilator, fluid and physical therapies are also discussed in detail. All of the authors are directly involved in ICU research and practice and are familiar with all of the latest developments in this fast-moving field of medicine.
Download or read book Congenital Bleeding Disorders written by Akbar Dorgalaleh and published by Springer. This book was released on 2018-07-25 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.
Download or read book Protocols for Bleeding and Thrombosis in Pediatric Intensive Care Units written by Rungrote Natesirinilkul and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bleeding and thrombosis are the common hematological complications found in children who are admitted in the pediatric intensive care units (PICUs). Some of those complications could be mild, however some could be serious or life-threatening for critically-ill children. The etiologies of those conditions could be due to the underlying diseases, i.e., congenital bleeding disorders, complications of the diseases, i.e. coagulopathy due to disseminated intravascular coagulation (DIC), and also the side effects from the treatments themselves, i.e., massive transfusion or extracorporeal membrane oxygenation (ECMO). Early detection and management and prevention of those complications could decrease the morbidity and mortality of the children in PICUs. Although most guidelines of management of those bleeding and thrombosis in adults is well established, the evidences for the management of those conditions in children are limited. In addition, developmental hemostasis during the childhood, which is different from adulthood, could challenge the management of those conditions in children admitted in PICUs.
Download or read book Hemocoagulative Problems in the Critically Ill Patient written by Giorgio Berlot and published by Springer. This book was released on 2012-04-11 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the very beginning of critical care medicine, much attention has been paid to the risk of bleeding, but only recently the risk of thrombosis has been recognized in critical patients; in fact, current laboratory investigations aimed to monitor blood coagulation are more focused on the assessment of the hemorrhagic than of the thrombotic risk. Since mid-90s, many studies have detected powerful pro-thrombotic actions of endogenous mediators in sepsis and other inflammatory conditions, including trauma and postoperative status. Unfortunately, the related complication are both hard to detect and extremely harmful. The volume provides a full coverage of the hemocoagulative problems in anesthesia and intensive care, taking into consideration the physiology and monitoring of hemostasis, its relation with sepsis, and the specific aspects of the various critical conditions - from trauma to burns, to heart and transplant surgery or acute renal failure.
Download or read book Coagulation Endothelial Dysfunction an Issue of Critical Care Clinics written by Hernando Gomez and published by Elsevier. This book was released on 2020-04-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Critical Care Clinics, guest edited by Drs. Hernando Gomez Danies and Joseph Carcillo, focuses on Coagulation/Endothelial Dysfunction. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Cell-cell communication breakdown and endothelial dysfunction; Role of the Tie2/Angiopoetin pathway in endothelial dysfunction; The Glycocalyx; Platelet activation and endothelial dysfunction; Role of antithrombin III and tissue factor pathway; Red blood cell dysfunction; Microvascular hemodynamics, autoregulation and mechanotransduction control of blood flow distribution; Nitric oxide and endothelial dysfunction; Microvascular dysfunction; Hemolytic Uremic Syndrome and atypical HUS; Thrombotic thrombocytopenic purpura, Heparin induced thrombocytopenia and Disseminated intravascular coagulation in the critically ill; Thrombocytopenia associated multiple organ failure (TAMOF); Meningococcemia; Immune consequences of endothelial dysfunction during sepsis; Therapeutic targets in thrombotic microangiopathies with a focus on endothelial disorders; and Coagulation disorders in HLH/Macrophage activation syndrome.
Download or read book Acute Pulmonary Embolism written by A. Geibel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- New developments in the thrombolytic therapy of venous thrombosis.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.MR-angiography in the diagnosis of pulmonary embolism.Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- Clinical course and prognosis of acute pulmonary embolism.- The molecular mechanisms of inherited thombophilia.
Download or read book Practical Emergency Resuscitation and Critical Care written by Kaushal Shah and published by Cambridge University Press. This book was released on 2023-10-31 with total page 655 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of a succinct and portable text reviewing the clinical approach to emergency medicine and critical care.
Download or read book Consultative Hemostasis and Thrombosis E Book written by Craig S. Kitchens and published by Elsevier Health Sciences. This book was released on 2013-02-20 with total page 843 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today’s newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout.
Download or read book Cardiothoracic Critical Care written by Natalia S. Ivascu and published by Oxford University Press, USA. This book was released on 2020 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Practicing critical care entails understanding human physiology, pharmacokinetics and molecular pathways in concert with adherence to evidence based literature. Some may say combining all of these entities into practice creates the "art" of critical care medicine. One strategy to gain proficiency in the practice of critical care medicine is to simulate what you would do in specific problem-based scenarios. That is the aim of this textbook aptly titled" "What Do I Do Now?" This text focuses on Cardiothoracic Critical Care and will cover guidelines for evidence-based practice, respiratory and metabolic physiology, common hemodynamic perturbations, ventricular failure and mechanical circulatory support devices. All clinicians who care for cardiothoracic patients who are critically ill can find pearls of practice wisdom complemented by literature citations within this text. So go ahead, place yourself at the foot of the bed and try to think through, "What Would I Do Now" when presented with each patient within these pages of your handheld cardiothoracic intensive care unit"--
Download or read book Core Topics in Critical Care Medicine written by Fang Gao Smith and published by Cambridge University Press. This book was released on 2010-04-22 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critical care unit manages patients with a vast range of disease and injuries affecting every organ system. The unit can initially be a daunting environment, with complex monitoring equipment producing large volumes of clinical data. Core Topics in Critical Care Medicine is a practical, comprehensive, introductory-level text for any clinician in their first few months in the critical care unit. It guides clinicians in both the initial assessment and the clinical management of all CCU patients, demystifying the critical care unit and providing key knowledge in a concise and accessible manner. The full spectrum of disorders likely to be encountered in critical care are discussed, with additional chapters on transfer and admission, imaging in the CCU, structure and organisation of the unit, and ethical and legal issues. Written by Critical Care experts, Core Topics in Critical Care Medicine provides comprehensive, concise and easily accessible information for all trainees.
Download or read book Pediatric Bleeding Disorders written by Amy L. Dunn and published by Springer Nature. This book was released on 2020-03-28 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This clinical casebook provides a concise, state-of-the-art review of pediatric bleeding disorders. Presented in a case-based format, each case presents a different variant of bleeding disorder, illustrates the etiology, pathology, genetics, diagnosis, and management of the disorder, and offers clinical pearls. Disorders covered include hemophilia A and B, rare factor deficiencies, von Willebrand disease, immune thrombocytopenia purpura, and platelet dysfunctions. Written by experts in the field, Pediatric Bleeding Disorders: A Clinical Casebook is a valuable resource for clinicians and practitioners treating patients with challenging coagulation issues.
Download or read book Smith s Anesthesia for Infants and Children E Book written by Peter J. Davis and published by Elsevier Health Sciences. This book was released on 2016-10-15 with total page 1829 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now thoroughly up to date with new chapters, Smith’s Anesthesia for Infants and Children, 9th Edition, by Drs. Peter Davis and Franklyn Cladis, covers the information you need to provide effective perioperative care for any type of pediatric surgery. Leading experts in pediatric anesthesia bring you up to date with every aspect of both basic science and clinical practice, helping you incorporate the latest clinical guidelines and innovations in your practice. Quick-reference appendices: drug dosages, growth curves, normal values for pulmonary function tests, and a listing of common and uncommon syndromes. Outstanding visual guidance in full color throughout the book. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. More than 100 video demonstrations, including new regional anesthesia videos, echocardiograms of congenital heart lesions, anatomic dissections of various congenital heart specimens with audio explanations, various pediatric surgical operative procedures, airway management, and much more. Table of Contents has been reorganized and new chapters added on statistics, sedation, pediatric obesity, and cardiac critical care pediatrics. A new chapter on regional anesthesia for pediatrics, including video and ultrasound demonstrations online. A new chapter on dermatology, specifically for the anesthesiologist, with more than 100 photos. A new chapter on medical missions to third-world countries, including what you should know before you go. A new Questions chapter provides opportunities for self-assessment. New coverage includes cardiac anesthesia for congenital heart disease, anesthesia outside the operating room, and a new neonatology primer for the pediatric anesthesiologist.
Download or read book Complications in Neuroanesthesia written by Hemanshu Prabhakar and published by Academic Press. This book was released on 2016-02-11 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complications in Neuroanesthesia focuses on complications that may arise related to neuroanesthesia practice and discusses its various causes. Each complication is written as a separate chapter, and the pathophysiology and mechanisms of each complication, as well as measures for diagnosis, treatment and prevention are discussed. Towards the end of the book, several case scenarios are provided to the readers that challenge readers to diagnose the possible complication for each case. Chapters include brain and spinal cord problems, cardiovascular and hematological problems, and nerve and muscle problems. Written in a standard format, Complications in Neuroanesthesia provides quick and easy access to understanding problems in neuroanesthesia. It provides insight into all possible complications occurring during perioperative management of neurosurgical and neurologic patients. It is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, and neurology by providing an understanding of preventable mishaps that may occur in neurosurgical or neurologic patients. Quick and easy reference for understanding problems in neuroanesthesia Provides comprehensive insights into all possible complications occurring during perioperative management of neurosurgical and neurologic patients Includes useful section with clinical case studies of complications in neuroanesthesia
