Download or read book Leong s Manual of Diagnostic Biomarkers for Immunohistology written by Runjan Chetty and published by Cambridge University Press. This book was released on 2022-06-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: With the interest in biomarkers available for diagnostic, therapeutic, prognostic and research applications growing rapidly, it is now expected that every pathologist should be aware of the correct application of immunohistochemistry in daily practice. This fully updated fourth edition provides practical guidance about preparation, key uses and pitfalls of antibodies for immunohistology in a unique A-Z format. Seventeen full colour infographics present detail about specific biomarkers, including FOXL2, GATA3 and SOX10, pulling out information about expression in tissues and prognosis. Expanded with new biomarkers and the removal of biomarkers that are no longer in common use, each entry in this concise new edition follows a standard structure for quick and easy access by busy readers.
Download or read book Leong s Manual of Diagnostic Antibodies for Immunohistology written by Runjan Chetty and published by Cambridge University Press. This book was released on 2016-11-28 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: A detailed, A-Z guide and an indispensable source for pathologists ensuring correct application of immunohistochemistry in daily practice.
Download or read book Manual of Diagnostic Antibodies for Immunohistology written by Anthony Siew-Yin Leong and published by Cambridge University Press. This book was released on 2003 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated edition provides a comprehensive list of antisera and monoclonal antibodies that have useful diagnostic applications.
Download or read book Manual of Diagnostic Antibodies for Immunohistology written by Anthony S. Y Leong and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Diagnostics written by Jan Trost Jorgensen and published by CRC Press. This book was released on 2019-05-08 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book provides a thorough overview of developing molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. The book takes the reader through definitions of the pharmacodiagnostic concept, historical perspectives of the early steps into molecular cancer diagnostics linked to therapy, the basis of different diagnostic molecular techniques, ongoing research, drug-diagnostic co-development, assay validation, clinical trial methodology, regulatory issues around pharmacodiagnostics and future aspects within personalized cancer medicine.
Download or read book Manual of Diagnostic Antibodies for Immunohistology written by Anthony Siew-Yin Leong and published by . This book was released on 1999 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date listing of the sources of immunochemicals for use in laboratory-based specialties such as Histopathology. Much more than just a catalogue of these chemicals, it includes specific technical details on the application and specificities of antisera, common pitfalls in use and how to avoid them, an aspect not covered in other similar texts.
Download or read book Diagnostic Immunohistochemistry E Book written by David J Dabbs and published by Elsevier Health Sciences. This book was released on 2017-11-29 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: User-friendly and concise, the new edition of this popular reference is your #1 guide for the appropriate use of immunohistochemical stains. Dr. David J. Dabbs and leading experts in the field use a consistent, organ system approach to cover all aspects of the field, with an emphasis on the role of genomics in diagnosis and theranostic applications that will better inform treatment options. Each well-written and well-researched chapter is enhanced with diagnostic algorithms, charts, tables, and superb, full-color histologic images, making this text a practical daily resource for all surgical pathologists. Features a systematic approach to the diagnostic entities of each organ system, including detailed differential diagnoses, diagnostic algorithms, and immunohistograms that depict immunostaining patterns of tumors. Covers many more antigens than other texts, and discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Contains new material on non-lymphoid malignancies, Hodgkin/non-Hodgkin lymphoma, and an expanded chapter on digital imaging and quantilative immunohistochemistry. Provides new grading schemes for several organs, along with new antibodies to cover more genomic immunohistochemistry applications. Offers more emphasis in the breast section of "eyes on" tissue for molecular/IHC prognostics compared to the current trend of gene-expression profiling of breast cancer.
Download or read book Modern Immunohistochemistry written by Peiguo Chu and published by Cambridge University Press. This book was released on 2014-02-27 with total page 1179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of this best-selling book in 2009, the field of immunohistochemistry has advanced significantly. Fully updated to reflect the latest developments in the field, Modern Immunohistochemistry, Second Edition, is a practical guide to all the important diagnostic markers in each organ system. Concise text is supplemented by over 1,100 high-quality colour images and algorithms. The new edition features even more summary tables, highlighting the key points of differential immunophenotypic panels. A new, expanded introduction explains the basic principles of immunohistochemistry, and chapters have been updated to incorporate predictive/prognostic markers and the latest WHO classifications. All chapters are written by the same expert authors, providing a consistent, engaging style throughout and avoiding contradictory advice. An essential text for residents, this is also an extremely valuable resource for practitioners in anatomic pathology wishing to familiarise themselves with diagnostic markers at a quick glance.
Download or read book Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma written by Michael J. Murphy and published by Springer Science & Business Media. This book was released on 2011-12-02 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes both the technologies used in the discovery of melanoma biomarkers and the clinical application of these biomarkers for diagnosis and staging of disease, determination of prognosis, treatment planning, monitoring of response to therapy, identification of novel therapeutic targets and drug development. A broad range of biomarkers (DNA/chromosomal, mRNA, microRNA, mitochondrial DNA, epigenetic and protein) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably play a greater role in the management of patients with this disease. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma is an essential resource for oncologists, dermatologists, dermatopathologists, general pathologists with an interest in melanoma, and melanoma researchers.
Download or read book Tumors in Domestic Animals written by Donald J. Meuten and published by John Wiley & Sons. This book was released on 2016-11-08 with total page 1000 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumors in Domestic Animals, Fifth Edition is a fully revised new edition of the most comprehensive and authoritative reference on veterinary tumor pathology in common domestic animals, now in full color throughout with the most current advances in research and diagnostics. Now in full color with hundreds of exquisite new images showing diagnostic features, pathogenesis, and techniques Adds new sections on relevant clinical pathology and oncology Updated throughout to include the very latest advances in research and diagnostics Takes a logical, user-friendly system approach Written by leading experts on animal tumor pathology
Download or read book Diagnostic Immunohistochemistry E Book written by David J Dabbs and published by Elsevier Health Sciences. This book was released on 2021-11-23 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through five well-regarded editions, Dr. David Dabbs’ Diagnostic Immunohistochemistry has set the standard for concise, complete, guidance on the use and interpretation of immunohistochemical stains. The 6th Edition continues this tradition of excellence, bringing you fully up to date with all aspects of this dynamic field. Easy to use and understand, this practical resource distills the large body of information on immunohistochemistry into a single, convenient reference that is invaluable for today’s surgical pathologists. Covers all aspects of the field, with an emphasis on the role of genomics in diagnosis and theranostic applications that will better inform treatment options. Includes the latest grading schemes in several organs along with new antibodies to cover more genomic immunohistochemistry applications. Contains current biomarker guidelines and up-to-date references throughout. Offers a systematic approach to the diagnostic entities of each organ system, including detailed differential diagnoses, diagnostic algorithms, and immunohistograms that depict immunostaining patterns of tumors. Contains numerous charts and tables, as well as 1,500 high-quality color histologic images that assist in making a definitive diagnosis. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Covers many more antigens than other texts, and discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval.
Download or read book In Situ Molecular Pathology and Co expression Analyses written by Gerard J. Nuovo and published by Academic Press. This book was released on 2020-09-03 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major advancements in the field of in situ molecular pathology have occurred since publication of the first edition. In Situ Molecular Pathology and Co-expression Analyses, Second Edition, continues to teach both the molecular basis for the improvements and the actual protocols. This is the unique feature that separates it from the pack of other "cook-book" type approaches. The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods. Further, knowledge of the marked improvements in the reagents themselves since the first edition can make the difference of excellent versus misleading data. The automated platforms require that researchers and diagnostic biomedical investigators have a good understanding of the basics of in situ based tests, protocols, and biochemistry for troubleshooting in order to maximize the use of these platforms. This second edition focuses attention on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. Practicing molecular pathologists, diagnostic pathologists, laboratory directors, and toxicologists, as well as clinicians and researchers in training, will benefit from this clear presentation of protocols and theoretical framework. Data derived from in situ hybridization and immunohistochemistry. Explains the theory and foundation of immunohistochemistry and in situ hybridization and presents easy-to-follow experimental protocols with tricks of the trade Includes two new chapters: Recent improvements in immunohistochemistry and in situ hybridization, Quality control for immunohistochemistry and in situ hybridization: How to know if the color change is signal or background The second edition also includes a detailed test to help one learn the basics of histologic interpretation of tissues and a separate detailed test in how to differentiate signal from background Includes chapter-ending summaries of Key Points to Remember, bringing beginners up to speed with any seasoned veteran in the field Thoughtfully tackles the molecular basis if IHC and ISH, along with application of that knowledge to improving the techniques is significant
Download or read book Canine and Feline Cytology E Book written by Rose E. Raskin and published by Elsevier Health Sciences. This book was released on 2015-05-11 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a ‘go-to’ reference text for a serious cytologist. " Reviewed by: Kathleen Tennant on behalf of Veterinary Record, November 2015 Comprehensive coverage of all body systems and body fluids — and the pathological changes associated with various infectious agents — emphasizes areas in which the application of cytology has the greatest diagnostic value. Exceptional-quality, full-color photomicrographs show both normal and abnormal tissue and also include detailed legends. Discussions of clinical, differential, and cytological diagnosis accompany the illustrations of lesions and conditions in each chapter. Helpful hints for improving specimen quality are provided in discussions of common errors and problems encountered in the preparation of cytological specimens. Coverage of histology in organ system chapters demonstrates the histological or histopathologic corollary of cytologic findings. Clear, concise descriptions include sampling techniques, slide preparation and examination, and guidelines for interpretation, leading to accurate in-house and commercial laboratory diagnosis. Easy-to-use, well-organized format includes many tables, algorithms, boxes, and Key Point callouts for at-a-glance reference. NEW examples and identifiers and a new discussion on artifacts address the latest developments in canine and feline cytology. NEW! Dozens of new images include photomicrographs of blood and bone marrow cytology. NEW! All-new appendix summarizes clinically relevant information on artifacts, special tests, specific characteristics, and much more. UPDATED sampling techniques and examination guidelines include information on how and where to test for specific conditions.
Download or read book Practical Breast Pathology A Diagnostic Approach E Book written by Kristen A. Atkins and published by Elsevier Health Sciences. This book was released on 2012-10-29 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Apply a systematic pattern recognition method to achieve more accurate diagnoses with Practical Breast Pathology: A Diagnostic Approach. Using a practical, pattern-based organization, this volume in the Pattern Recognition series guides you efficiently and confidently through the evaluation of even the most challenging neoplastic and non-neoplastic specimens in breast pathology, and also highlights patterns crucial to radiologic diagnosis. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Compare specimens to commonly seen patterns, categorize them accordingly, and turn directly to in-depth diagnostic guidance using the unique, pattern-based Visual Index at the beginning of the book. Assess key pathologic and clinical aspects of both neoplastic and non-neoplastic conditions with over 530 high-quality, full-color images that help you evaluate and interpret biopsy samples. Apply the latest techniques and advances in the field, including optimal processing of breast specimens for early detection of breast cancer, the latest molecular diagnosis in breast pathology, and the use of radiology in optimizing detection of breast lesions. Progress logically from the histological pattern, through the appropriate work-up, around the pitfalls, and to the best diagnosis. Find the information you’re looking for quickly and easily with patterns color-coded to specific entities in the table of context and text and key points summarized in tables, charts, and graphs. Review all the information essential for completing a sign-out report: clinical findings, pathologic findings, diagnosis, treatment, and prognosis. View key diagnostic features associated with less common conditions in a visual encyclopedia of unusual patterns at the end of the book.
Download or read book Technical Aspects of Toxicological Immunohistochemistry written by Syed A. Aziz and published by Humana Press. This book was released on 2015-12-23 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative volume examines immunohistochemical methods aimed at investigating the toxicologic pathology of rodent, non-human primate and aquatic animal tissues. Eleven comprehensive chapters provide pathologists and researchers in various sub-disciplines of toxicology with a comprehensive review of the methods and approaches for immunohistochemical staining in various target tissues. It explores the tissue-antigen and antibody-specific problems that may be encountered during the staining procedures and provide potential avenues for resolving various methodological issues. Special attention is paid to the latest enhancement procedures for antigen retrieval and visualization as well as image analysis and antigen quantification. Written by leading researchers in toxicology and pathology, this book is a significant resource for toxicologists and pathologists working with rodents, monkeys and aquatic animal tissues.
Download or read book Handbook of Practical Immunohistochemistry written by Fan Lin and published by Springer. This book was released on 2015-02-21 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a conceptually current, quick-reference, Question & Answer format, the second edition of Handbook of Practical Immunohistochemistry: Frequently Asked Questions continues to provide a comprehensive and yet concise state-of-the-art overview of the major issues specific to the field of immunohistochemistry. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 10,000 tumors and normal tissue to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes. Fully revised and updated from the first edition, the new features of the second edition include over 200 additional questions or revised questions with an IHC panel to answer each question; over 250 new color photos and illustrations; over 20 new useful biomarkers; hundreds of new references; several new chapters to cover phosphoproteins, rabbit monoclonal antibodies, multiplex IHC stains, overview of predictive biomarkers, and integration of IHC into molecular pathology; many new coauthors who are international experts in a related field; many updated IHC panels using Geisinger IHC data collected from over 10,000 tumors and normal tissues; and updated appendices containing detailed antibody information for both manual and automated staining procedures. Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, Second Edition will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.
Download or read book Diagnostic Immunohistochemistry written by David J. Dabbs and published by Churchill Livingstone. This book was released on 2006 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers current information and guidance on immunohistochemical diagnoses in surgical pathology and cytopathology. The book is organized in a consistent format of organ systems, specifically designed to target diagnostic dilemmas in surgical pathology. Each chapter features an introduction and a systematic approach to the diagnostic entities of that organ system. Provides a reference for pathologists practicing diagnostic surgical pathology and cytopathology. Structured in the organ-system approach to tumor pathology, with each chapter capable of standing alone. Extensive references and full-color illustrations are included.
