Download or read book Leading edge Immunology Research written by Barbara A. Veskler and published by Nova Publishers. This book was released on 2006 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology is the study of the body's protection from foreign macromolecules or invading organisms and the responses to them. These invaders include viruses, bacteria, protozoa or even larger parasites. In addition, immune responses are developed against our own proteins (and other molecules) in autoimmunity and against our own aberrant cells in tumor immunity. The first line of defense against foreign organisms are barrier tissues such as the skin that stop the entry of organism into our bodies. A second line of defense is the specific or adaptive immune system which may take days to respond to a primary invasion (that is infection by an organism that has not hitherto been seen). This new book brings together new research from around the globe dealing with this extremely important subject.
Download or read book Immunity written by William E. Paul and published by JHU Press. This book was released on 2015-11-15 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: A leading figure in immunology takes readers inside the remarkably powerful human immune system. Winner of the CHOICE Outstanding Academic Title of the Choice ACRL The immune system has incredible power to protect us from the ravages of infection. Boosted by vaccines, it can protect us from diseases such as measles. However, the power of the immune system is a double-edged sword: an overactive immune system can wreak havoc, destroying normal tissue and causing diseases such as type I diabetes, rheumatoid arthritis, and multiple sclerosis. The consequences of an impaired immune system, on the other hand, are all too evident in the agonies of AIDS. Packed with illustrations, stories from Dr. William E. Paul’s distinguished career, and fascinating accounts of scientific discovery, Immunity presents the three laws of the human immune system—universality, tolerance, and appropriateness—and explains how the system both protects and harms us. From the tale of how smallpox was overcome and the lessons of the Ebola epidemic to the hope that the immune system can be used to treat or prevent cancer, Dr. Paul argues that we must take advantage of cutting-edge technologies and promising new tools in immunological research.
Download or read book Immunology written by Stephen Juris and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Immunology offers the most contemporary perspective on the science available, providing a clear, easy-to-follow introduction to the discipline suitable for undergraduate students. In a course where students often get lost in vast amounts of detail and the sheer complexity of the immune response, Immunology helps students see "the big picture" with an approachable narrative that presents the exquisite details of immunology while emphasizing the connections between key themes that students so often lose sight of when learning the material. Immunology features an exceptional illustration program and includes simple, clear explanations, abundant examples, and features that unravel the mysteries of immunology through accounts of classical discoveries and recent, cutting-edge research. Since many students in the course are preparing to enter careers in research, medicine, and other health professions, an appropriate amount of applied knowledge and clinical content is included in the narrative, features, and engaging case studies. Students will easily be able to make connections, moving beyond memorizing just what we know to truly understanding how we know what we know-and why"--
Download or read book Computational Immunology written by Josep Bassaganya-Riera and published by Academic Press. This book was released on 2015-10-21 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. Offers case studies with different levels of complexity Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting
Download or read book Immunotherapy written by Aung Naing and published by Springer Nature. This book was released on 2022-01-01 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of immuno-oncology continues to rapidly evolve as new insights to fight and treat cancer emerge. The fourth edition of Immunotherapy provides the most current overview of immuno-oncology in different cancer types and toxicities associated with immunotherapy. While immunotherapy has revolutionized the treatment landscape of several solid malignancies, several challenges still exist. Only a subset of patients derive clinical benefits; some do not respond at all, and others respond initially, only for their disease to progress later. Because these drugs can activate a broad range of immune cells, patients suffer from a unique set of side effects known as immune-related adverse events. As more immunotherapeutic agents are used in the clinic, it is important to provide updates about current and ongoing developments in the field to further research efforts and inform treatment decisions. The fourth edition will have a new focus on strategies to overcome the challenges associated with immunotherapy. Chapters will discuss topics such as biomarkers of response, resistance mechanisms, role of imaging in predicting immune-related adverse events, and management of immune-related adverse events. Written by leading experts conducting cutting-edge research, readers will gain up-to-date knowledge on the current state and future of immunotherapy.
Download or read book Immunology of Infection written by and published by Academic Press. This book was released on 2010-09-23 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology of Infection, 3e, edited by two leading experts in the field, presents the most appropriate up-to-date experimental approaches in the detail required for modern microbiological research. Focusing on the methods most useful for the microbiologist interested in analyzing host-pathogen relationships, this volume will be essential reading for all researchers working in microbiology, immunology, virology, mycology and parasitology. This new edition of Immunology of Infection provides ready-to-use "recipes" and the latest emerging techniques as well as novel approaches to the tried and tested, established methods included in the successful first edition. Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Established for over 30 years, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research.
Download or read book Clinical Immunology Principles and Practice Expert Consult Online and Print 4 written by Thomas A. Fleisher and published by Elsevier Health Sciences. This book was released on 2013-01-01 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and edited by international leaders in the field, this book has, through two best-selling editions, been the place to turn for authoritative answers to your toughest challenges in clinical immunology. Now in full color and one single volume, the 3rd Edition brings you the very latest immunology knowledge - so you can offer your patients the best possible care. The user-friendly book and the fully searchable companion web site give you two ways to find the answers you need quickly...and regular online updates keep you absolutely current. Leading international experts equip you with peerless advice and global best practices to enhance your diagnosis and management of a full range of immunologic problems. A highly clinical focus and an extremely practical organization expedite access to the answers you need in your daily practice. Cutting-edge coverage of the human genome project, immune-modifier drugs, and many other vital updates keeps you at the forefront of your field. A new organization places scientific and clinical material side by side, to simplify your research and highlight the clinical relevance of the topics covered. A multimedia format allows you to find information conveniently, both inside the exceptionally user-friendly book and at the fully searchable companion web site. Regular updates online ensure that you'll always have the latest knowledge at your fingertips. Includes many new and improved illustrations and four color design. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
Download or read book B Cells in Immunity and Tolerance written by Ji-Yang Wang and published by Springer Nature. This book was released on 2020-04-22 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.
Download or read book Innate Immunity written by R. Alan B. Ezekowitz and published by Springer Science & Business Media. This book was released on 2002-12-06 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of innate immunity refers to the first-line host defense that serves to limit infection in the early hours after exposure to microorganisms. Recent data have highlighted similarities between pathogen recognition, signaling pathways, and effector mechanisms of innate immunity in Drosophila and mammals, pointing to a common ancestry of these defenses. In addition to its role in the early phase of defense, innate immunity in mammals appears to playa key role in stimulating the subsequent clonal response of adaptive immunity. Recent exciting information has determined that the templates that are laid down in primitive life forms, like flowering plants and insects, form the basic principles of first line host defense that are conserved in mammalian systems. The next frontier in the field is to understand the dynamic adaptive changes that occur as a result of the inter play between host defenses and infectious agents. One emerging theme is that microorganisms are constantly seeking ways to co-opt host defenses. On the other hand, host defense to infection is mediated by the coordinate action of pattern recognition molecules and receptors that, in mammals, are important and probably necessary antecedents to the development of an adaptive immune response. Innate Immunity aims to explore the intersection between host pathogen interactions across an evolutionary spectrum that will inform our understanding of the dynamic interplay between infectious agents and host defense in man.
Download or read book Mathematical Computational and Experimental T Cell Immunology written by Carmen Molina-París and published by Springer Nature. This book was released on 2021-01-04 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical, statistical, and computational methods enable multi-disciplinary approaches that catalyse discovery. Together with experimental methods, they identify key hypotheses, define measurable observables and reconcile disparate results. This volume collects a representative sample of studies in T cell immunology that illustrate the benefits of modelling-experimental collaborations and which have proven valuable or even ground-breaking. Studies include thymic selection, T cell repertoire diversity, T cell homeostasis in health and disease, T cell-mediated immune responses, T cell memory, T cell signalling and analysis of flow cytometry data sets. Contributing authors are leading scientists in the area of experimental, computational, and mathematical immunology. Each chapter includes state-of-the-art and pedagogical content, making this book accessible to readers with limited experience in T cell immunology and/or mathematical and computational modelling.
Download or read book Molecular Immunology written by Andrew Hook and published by Independently Published. This book was released on 2024-06-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Immunology: How the Immune System Fights Disease The immune system is a marvel of biological engineering, a complex network of cells and molecules that constantly patrol our bodies, protecting us from harmful invaders. From the moment we are born, this incredible system is at work, identifying and neutralizing threats, and ensuring our survival in a world teeming with pathogens. It is an intricate dance of recognition and response, precision and power, that keeps us healthy every day. But what if we could look closer, beyond the surface of this fascinating system? What if we could go into the molecular machinery that drives these life-saving processes? This is the realm of molecular immunology. It is here, at the molecular level, where the true magic happens-where genes are regulated, signals are transmitted, and immune cells are activated in ways that determine our health and well-being. Studying the molecular aspects of the immune system is crucial. It allows us to understand the finer details of how immune responses are initiated, regulated, and sometimes go awry. This knowledge is the foundation for developing new therapies and vaccines, diagnosing diseases more accurately, and even preventing illnesses before they start. By understanding the molecular underpinnings, we can unlock new potentials in medicine and public health. In "Molecular Immunology: How the Immune System Fights Disease," you will learn about: The fundamental components of the immune system and their molecular signatures. The genetic and epigenetic regulation of immune cells. Signal transduction pathways that drive immune responses. The diversity of immune receptors is generated through sophisticated mechanisms like V(D)J recombination. How memory cells are formed and maintained for long-lasting immunity. The molecular basis of various immune-related diseases, including autoimmune disorders, allergies, and cancers. Cutting-edge therapeutic applications such as monoclonal antibodies, gene therapy, and CRISPR technology. Emerging technologies and the future directions of molecular immunology research. This book is designed to provide a comprehensive yet accessible overview of molecular immunology, making complex concepts understandable and fascinating. Whether you are a student, a healthcare professional, or simply someone interested in the marvels of the immune system, this book will equip you with valuable knowledge and insights. Please go into the molecular world of the immune system and discover how it fights disease. Gain a deeper understanding of the mechanisms that protect us and learn how this knowledge transforms medicine. Start your exploration today with "Molecular Immunology: How the Immune System Fights Disease." Your understanding of the immune system will never be the same.
Download or read book Experiments in International Benchmarking of US Research Fields written by Institute of Medicine and published by National Academies Press. This book was released on 2000-02-28 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: How can the federal government gauge the overall health of scientific researchâ€"as a whole and in its partsâ€"and determine whether national funding adequately supports national research objectives? It is feasible to monitor US performance with field-by-field peer assessments. This might be done through the establishment of independent panels consisting of researchers who work in a field, individuals who work in closely related fields, and research "users" who follow the field closely. Some of these individuals should be outstanding foreign scientists in the field being examined. This technique of comparative international assessments is also known as international benchmarking. Experiments in International Benchmarking of U.S. Research Fields evaluates the feasibility and utility of the benchmarking technique. In order to do this, the report internationally benchmarks three fields: mathematics, immunology, and materials science and engineering, then summarizes the results of these experiments.
Download or read book Influenza the Cutting Edge written by Gabriele Neumann and published by . This book was released on 2020 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A subject collection from Cold Spring Harbor perspectives in medicine".
Download or read book Suppression and Regulation of Immune Responses written by Maria Cristina Cuturi and published by Humana. This book was released on 2015-11-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second volume expands upon the previous edition with new research and objectives in immunoregulation and immune tolerance. Chapters cover topics ranging from new molecular and cellular mechanisms of tolerance; generation and characterization of mice regulatory macrophages; recent advances in the treatment of immune-mediated inflammatory disorders; and novel mechanisms and therapeutic perspectives on food allergies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols, Volume II is a great resource for current research and inspiration for new studies in immune tolerance.
Download or read book Suppression and Regulation of Immune Responses written by Maria Cristina Cuturi and published by . This book was released on 2011 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second volume expands upon the previous edition with new research and objectives in immunoregulation and immune tolerance. Chapters cover topics ranging from new molecular and cellular mechanisms of tolerance; generation and characterization of mice regulatory macrophages; recent advances in the treatment of immune-mediated inflammatory disorders; and novel mechanisms and therapeutic perspectives on food allergies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols, Volume II is a great resource for current research and inspiration for new studies in immune tolerance.
Download or read book Vaccinology and Methods in Vaccine Research written by Rebecca Ashfield and published by Elsevier. This book was released on 2022-03-16 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccinology and Methods in Vaccine Research is a combination of cutting-edge methodologies, experimental approaches and literature reviews. The book covers all aspects of vaccine development, including basic immunology (focusing on the stimulation of adaptive immunity, which is required for vaccine efficacy), approaches to vaccine design and target validation, vaccine biomanufacturer and clinical development. Existing vaccinology resources are theoretical reference books, whereas this book provides a practical handbook for use in the research lab and classroom by those working in vaccinology and training others in the field. It is authored and edited by scientists actively engaged in vaccine research and development for day-to-day teaching/methodological advice. Addresses how to design a vaccine for an emerging disease, from a practical point-of -view, with chapters written by scientists who are grappling with these questions Provides new approaches to vaccine development. including vaccine targeting and virus-like-particle vaccines Gives up-to-date information and methodologies in use for vaccine adjuvants
Download or read book Autophagy in Infection and Immunity written by Beth Levine and published by Springer. This book was released on 2012-03-14 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy is a fundamental biological process that enables cells to autodigest their own cytosol during starvation and other forms of stress. It has a growing spectrum of acknowledged roles in immunity, aging, development, neurodegeneration, and cancer biology. An immunological role of autophagy was first recognized with the discovery of autophagy’s ability to sanitize the cellular interior by killing intracellular microbes. Since then, the repertoire of autophagy’s roles in immunity has been vastly expanded to include a diverse but interconnected portfolio of regulatory and effector functions. Autophagy is an effector of Th1/Th2 polarization; it fuels MHC II presentation of cytosolic (self and microbial) antigens; it shapes central tolerance; it affects B and T cell homeostasis; it acts both as an effector and a regulator of Toll-like receptor and other innate immunity receptor signaling; and it may help ward off chronic inflammatory disease in humans. With such a multitude of innate and adaptive immunity functions, the study of autophagy in immunity is one of the most rapidly growing fields of contemporary immunological research. This book introduces the reader to the fundamentals of autophagy, guides a novice and the well-informed reader alike through different immunological aspects of autophagy as well as the countermeasures used by highly adapted pathogens to fight autophagy, and provides the expert with the latest, up-to-date information on the specifics of the leading edge of autophagy research in infection and immunity.
