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Book Laser induced Fluorescence for Medical Diagnostics

Download or read book Laser induced Fluorescence for Medical Diagnostics written by Stefan Andersson-Engels and published by . This book was released on 1989 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Applications of Laser induced Fluorescence to Medical Diagnostic Problems

Download or read book Applications of Laser induced Fluorescence to Medical Diagnostic Problems written by S. J. Davis and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Tracer based Planar Laser induced Fluorescence Diagnostics

Download or read book Tracer based Planar Laser induced Fluorescence Diagnostics written by Brian Ho-yin Cheung and published by Stanford University. This book was released on 2011 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two advances to tracer-based planar laser-induced fluorescence (PLIF) diagnostics are presented in this work. The first improvement is the development of a 3-pentanone fluorescence quantum yield (FQY) database and model for a wide range of conditions in support of quantitative PLIF diagnostics. In addition, this work presents a sensitive, time-resolved tracer-based PLIF diagnostic, accomplished by using a continuous-wave (CW) laser with the high-FQY tracer toluene. Because of its ease of use and desirable photophysical properties, PLIF diagnostics using 3-pentanone as a tracer are common, particularly for internal combustion engine (ICE) diagnostics. Thus, there is a need for 3-pentanone FQY measurements and modeling over a wide range of temperatures, pressures, and excitation wavelengths. For insight into the collisionless process in the FQY model, measurements were made in 3-pentanone vapor at low-pressures across a range of temperatures using a flowing cell. Laser excitation with 248, 266, 277, 308 nm wavelengths were utilized, and Rayleigh scattering of the laser beam was used to calibrate the optical efficiency of the collection optics and detector. This low-pressure data allows calculation of the 3-pentanone fluorescence rate and non-radiative de-excitation rate in the fluorescence model. The vibrational relaxation cascade parameter for 3-pentanone collisions was also determined. Measurements of 3-pentanone FQY were also made over a range of temperatures and pressures relevant to diagnostic applications, and, in particular, combined high-temperature and high-pressure conditions applicable to internal combustion engines (ICE). These data were collected in a custom-built optical cell capable of simultaneous high-pressure and high-temperature conditions. The behavior of the FQY in nitrogen for temperatures up to 745 K and in air up to 570 K was examined for pressures from 1 to 25 bar. These data were used to further optimize the parameters in the FQY model representing collisional processes. The large quantity of data with 308 nm excitation allowed optimization of the nitrogen quenching rate, and data in air were used to optimize the oxygen quenching rate. These data were also used to optimize the vibrational relaxation parameters for nitrogen and oxygen. The model with the updated parameters is consistent with the data collected in the current work, as well as with fluorescence measurements made in optical ICEs up to 1100 K and 28 bar. Another area of tracer-based PLIF diagnostics development is time-resolved imaging. Because PLIF diagnostics are often performed using pulsed lasers, the time resolution of measurements is limited to the pulse rate of laser. Use of a high-powered visible laser with an off-the-shelf cavity frequency doubler is shown to produce a moderate-power CW beam in the ultraviolet wavelength regime. Application of this CW source to excite toluene, a high-FQY tracer, yields a sensitive, time-resolved tracer-based PLIF diagnostic. Fluctuation detection limits for tracer mole fraction were investigated by applying the diagnostic to an atmospheric temperature and pressure nitrogen jet seeded with 4% toluene, and detection limits of better than 1% of the maximum toluene mole fraction were achieved for detection of fluorescence signal at a point, along a line, and over a plane. The diagnostic was also demonstrated on a turbulent jet for line and planar detection and demonstrated the potential for toluene time-resolved PLIF diagnostics with CW lasers.

Book Optical and Laser Diagnostics

Download or read book Optical and Laser Diagnostics written by C Arcoumanis and published by CRC Press. This book was released on 2016-04-19 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the automotive industry to blood flow monitoring, optical techniques and laser diagnostics are becoming integral parts in engineering and medical instrumentation. Written by leading global experts from industry, academic groups, and laboratories, this volume provides an international perspective on both existing applications and leading-edge r

Book Laser induced Fluorescence Diagnostics Using a Two line Excitation Method

Download or read book Laser induced Fluorescence Diagnostics Using a Two line Excitation Method written by Michael S. Smith and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Tracer based Planar Laser induced Fluorescence Diagnostics

Download or read book Tracer based Planar Laser induced Fluorescence Diagnostics written by Brian Ho-yin Cheung and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Two advances to tracer-based planar laser-induced fluorescence (PLIF) diagnostics are presented in this work. The first improvement is the development of a 3-pentanone fluorescence quantum yield (FQY) database and model for a wide range of conditions in support of quantitative PLIF diagnostics. In addition, this work presents a sensitive, time-resolved tracer-based PLIF diagnostic, accomplished by using a continuous-wave (CW) laser with the high-FQY tracer toluene. Because of its ease of use and desirable photophysical properties, PLIF diagnostics using 3-pentanone as a tracer are common, particularly for internal combustion engine (ICE) diagnostics. Thus, there is a need for 3-pentanone FQY measurements and modeling over a wide range of temperatures, pressures, and excitation wavelengths. For insight into the collisionless process in the FQY model, measurements were made in 3-pentanone vapor at low-pressures across a range of temperatures using a flowing cell. Laser excitation with 248, 266, 277, 308 nm wavelengths were utilized, and Rayleigh scattering of the laser beam was used to calibrate the optical efficiency of the collection optics and detector. This low-pressure data allows calculation of the 3-pentanone fluorescence rate and non-radiative de-excitation rate in the fluorescence model. The vibrational relaxation cascade parameter for 3-pentanone collisions was also determined. Measurements of 3-pentanone FQY were also made over a range of temperatures and pressures relevant to diagnostic applications, and, in particular, combined high-temperature and high-pressure conditions applicable to internal combustion engines (ICE). These data were collected in a custom-built optical cell capable of simultaneous high-pressure and high-temperature conditions. The behavior of the FQY in nitrogen for temperatures up to 745 K and in air up to 570 K was examined for pressures from 1 to 25 bar. These data were used to further optimize the parameters in the FQY model representing collisional processes. The large quantity of data with 308 nm excitation allowed optimization of the nitrogen quenching rate, and data in air were used to optimize the oxygen quenching rate. These data were also used to optimize the vibrational relaxation parameters for nitrogen and oxygen. The model with the updated parameters is consistent with the data collected in the current work, as well as with fluorescence measurements made in optical ICEs up to 1100 K and 28 bar. Another area of tracer-based PLIF diagnostics development is time-resolved imaging. Because PLIF diagnostics are often performed using pulsed lasers, the time resolution of measurements is limited to the pulse rate of laser. Use of a high-powered visible laser with an off-the-shelf cavity frequency doubler is shown to produce a moderate-power CW beam in the ultraviolet wavelength regime. Application of this CW source to excite toluene, a high-FQY tracer, yields a sensitive, time-resolved tracer-based PLIF diagnostic. Fluctuation detection limits for tracer mole fraction were investigated by applying the diagnostic to an atmospheric temperature and pressure nitrogen jet seeded with 4% toluene, and detection limits of better than 1% of the maximum toluene mole fraction were achieved for detection of fluorescence signal at a point, along a line, and over a plane. The diagnostic was also demonstrated on a turbulent jet for line and planar detection and demonstrated the potential for toluene time-resolved PLIF diagnostics with CW lasers.

Book Laser Induced Fluorescence in Spectroscopy  Dynamics  and Diagnostics

Download or read book Laser Induced Fluorescence in Spectroscopy Dynamics and Diagnostics written by David R. Crosley and published by . This book was released on 1982 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Strategies for Planar Laser induced Fluorescence Thermometry in Shock Tube Flows

Download or read book Strategies for Planar Laser induced Fluorescence Thermometry in Shock Tube Flows written by Ji Hyung Yoo and published by Stanford University. This book was released on 2011 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis was motivated by the need to better understand the temperature distribution in shock tube flows, especially in the near-wall flow regions. Two main ideas in planar laser-induced fluorescence (PLIF) diagnostics are explored in this thesis. The first topic is the development of a single-shot PLIF diagnostic technique for quantitative temperature distribution measurement in shock tube flow fields. PLIF is a non-intrusive, laser-based diagnostic technique capable of instantaneously imaging key flow features, such as temperature, pressure, density, and species concentration, by measuring fluorescence signal intensity from laser-excited tracer species. This study performed a comprehensive comparison of florescence tracers and excitation wavelengths to determine the optimal combination for PLIF imaging in shock tube flow applications. Excitation of toluene at 248nm wavelength was determined to be the optimal strategy due to the resulting high temperature sensitivity and fluorescence signal level, compared to other ketone and aromatic tracers at other excitation wavelengths. Sub-atmospheric toluene fluorescence yield data was measured to augment the existing photophysical data necessary for this diagnostic technique. In addition, a new imaging test section was built to allow PLIF imaging in all regions of the shock tube test section, including immediately adjacent to the side and end walls. The signal-to-noise (SNR) and spatial resolution of the PLIF images were optimized using statistical analysis. Temperature field measurements were made with the PLIF diagnostic technique across normal incident and reflected shocks in the shock tube core flow. The resulting images show uniform spatial distribution, and good agreement with conditions calculated from the normal shock jump equations. Temperature measurement uncertainty is about 3.6% at 800K. The diagnostic was also applied to image flow over a wedge. The resulting images capture all the flow features predicted by numerical simulations. The second topic is the development of a quantitative near-wall diagnostic using tracer-based PLIF imaging. Side wall thermal boundary layers and end wall thermal layers are imaged to study the temperature distribution present under constant pressure conditions. The diagnostic technique validated in the shock tube core flow region was further optimized to improve near-wall image quality. The optimization process considered various wall materials, laser sheet orientations, camera collection angles, and optical components to find the configuration that provides the best images. The resulting images have increased resolution (15[Mu]m) and are able to resolve very thin non-uniform near-wall temperature layers (down to 60[Mu]m from the surface). The temperature field and thickness measurements of near-wall shock tube flows under various shock conditions and test gases showed good agreement with boundary layer theory. To conclude this thesis, new applications and future improvements to the developed PLIF diagnostic technique are discussed. These suggested refinements can provide an even more robust and versatile PLIF imaging technique capable of measuring a wider range of flow conditions near walls.

Book Application of Laser Induced Fluorescence for Flow Diagnostics in Arc Jets

Download or read book Application of Laser Induced Fluorescence for Flow Diagnostics in Arc Jets written by Sivaram Arepalli and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Demonstration of the Feasibility of Laser Induced Fluorescence for Arc Jet Flow Diagnostics

Download or read book Demonstration of the Feasibility of Laser Induced Fluorescence for Arc Jet Flow Diagnostics written by National Aeronautics and Space Administration (NASA) and published by Createspace Independent Publishing Platform. This book was released on 2018-07 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laser Induced Fluorescence (LIF) studies are carried out on nitric oxide and oxygen molecules in the arc jet flows at the NASA Johnson Space Center Reentry Testing Facility. Measurements are taken in the free stream and from a blunt body shock layer. Tests are performed under different flow conditions to determine the feasibility and sensitivity of the LIF technique for various species. This is developed as a part of high enthalpy flow diagnostics and will be useful to elucidate the rotational and vibrational temperatures. Adequate sensitivity for the detection of O(2) and NO is demonstrated. Proposed improvements of the existing system are presented. Arepalli, Sivaram Unspecified Center NAS9-17900...

Book Laser Induced Fluorescence Diagnostics in Multiphase Flows

Download or read book Laser Induced Fluorescence Diagnostics in Multiphase Flows written by Georgios Charalampous and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Laser Induced Fluorescence Spectroscopy for Combustion Diagnostics

Download or read book Laser Induced Fluorescence Spectroscopy for Combustion Diagnostics written by D. R. Crosley and published by . This book was released on 1983 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Photon Migration in Tissue

    Book Details:
  • Author : Henrik Nilsson
  • Publisher :
  • Release : 2002
  • ISBN : 9789173731799
  • Pages : 207 pages

Download or read book Photon Migration in Tissue written by Henrik Nilsson and published by . This book was released on 2002 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: