Download or read book Laboratory Techniques for Hematologic Malignancies written by Torsten Haferlach and published by . This book was released on 2012-04-15 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews diagnostic techniques including cytomorphology, histomorphology, cytogenetics, FISH, flow cytometry and molecular genetics. Includes algorithms for diagnosis and follow-up scenarios.
Download or read book Diagnostic Techniques in Hematological Malignancies written by Wendy N. Erber and published by . This book was released on 2014-05-14 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrative, comprehensive guide to the optimal utilization of laboratory techniques in diagnosing and monitoring hematological malignancies.
Download or read book Molecular Aspects of Hematologic Malignancies written by Michal Witt and published by Springer Science & Business Media. This book was released on 2012-06-30 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.
Download or read book Diagnostic Techniques in Hematological Malignancies written by Wendy N. Erber and published by Cambridge University Press. This book was released on 2010-11-11 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: The diagnosis and monitoring of hematological malignancies is complex and requires a systematic approach. Morphology, cell phenotyping, cytogenetics and molecular genetics are essential, and the results must be integrated. Diagnostic Techniques in Hematological Malignancies details the principles and applications of each of these test types in the diagnosis of hematological malignancies in blood and bone marrow. The first section describes the test modalities – including methodological principles, data interpretation and limitations – and is illustrated by clinical examples. The second section focuses on the clinical entities, detailing the most appropriate tests for diagnosis, staging and monitoring of different hematological malignancies and includes test utilization to identify prognostic markers and potential therapeutic targets. With contributions from multiple international experts, this illustrated book is an essential resource for qualified and trainee hematologists, oncologists, and pathologists. It's a practical and useful guide, providing a rational and structured approach to the laboratory assessment of hematological malignancies.
Download or read book Hematologic Malignancies written by Guy B. Faguet and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of Hematologic Malignancies: Methods and Techniques is to review those methods most useful for the diagnosis and subsequent mana- ment of hematologic malignancies. The scope of coverage is intentionally broad, ranging from routine procedures to highly sophisticated methods not currently offered by most clinical laboratories. The latter methods were selected especially to bring into focus recent advances in molecular biology that, since they provide us with strong tools for assessing the outcome of upcoming therapeutic modalities intent on disease eradication, are expected to impact the future diagnosis and management of these diseases. Thus, the c- mon thread among all chapters is clinical relevance, whether sanctioned by past experience or by the expectation that seemingly esoteric research techniques of today will prove clinically valuable in the future. Hematologic Malignancies: Methods and Techniques is primarily a compilation of methods presented in sufficient detail—by authors with extensive expertise in their field—to serve not only as a reference for seasoned research and clinical laboratory pers- nel, but also as a guide for the less experienced. Moreover, the contributing authors also discuss the pathophysiologic bases and the diagnostic usefulness that underscore each method’s clinical relevance. Thus, this volume should be also valuable to clinicians—especially hematologists, oncologists, and path- ogists—often bewildered by an ever increasing flow of new scientific inf- mation, the practical application of which is often either not clearly disclosed or difficult to discern.
Download or read book Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies written by Anna Porwit and published by Cambridge University Press. This book was released on 2018-01-25 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignancies. Authored by leading experts, this book puts flow-cytometry into everyday context. With a focus on multicolour panels, the manual provides readers an experienced understanding of effective, implementation techniques. Practitioners of all levels are offered a background in a variety of diseases presented alongside the most current methodology. Wide-ranging and comprehensive; detailed images of healthy blood, bone marrow and lymph-nodes are illustrated throughout, allowing for effective diagnosis. Through engaging with differential diagnoses, the manual offers an understanding of similar symptoms and mimicking malignancies, avoiding inaccurate results. Featuring in-depth descriptions of chronic diseases; users can reach accurate diagnosis, first time.
Download or read book Flow Cytometry in Hematopathology written by Doyen T. Nguyen and published by Springer Science & Business Media. This book was released on 2002-11-26 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flow cytometry immunophenotyping of hematopoietic disorders is a complex and demanding exercise that requires a good understanding of cell lineages, developmental pathways, and physiological changes, as well as broad experience in hematopathology. The process includes several interrelated stages, from the initial medical decision regarding which hematologic c- dition is appropriate for FCM assay, to the final step of diagnosis whereby the FCM data is correlated with other relevant clinical and laboratory information. The actual FCM testing involves three major steps: pre-analytical (specimen processing, antibody staining), analytical (acquiring data on the flow cytometer) and post-analytical (data analysis and interpretation). The literature, including the latest FCM textbooks, provides ample information on the te- nical principles of FCM such as instrumentation, reagents and laboratory methods, as well as quality control and quality assurance. Similarly, correlations of morphologic findings and p- notypic profiles have been well covered in many publications. In contrast, much less attention has been given to the other equally important aspects of FCM immunophenotyping, especially data analysis. The latter is a crucial step by which a phenotypic profile is established. To bridge this gap in the literature, the focus of this book is more on FCM data analysis than laboratory methods and technical details. For the reader to become familiar with our data analysis strategy, an overview of our approach to the pre-analytical and analytical steps is also presented, with an emphasis on the pre-analytical aspects, which have been rarely touched upon in the literature.
Download or read book Laboratory Hematology Practice written by Kandice Kottke-Marchant and published by John Wiley & Sons. This book was released on 2012-06-06 with total page 777 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expertly edited and endorsed by the International Society for Laboratory Hematology, this is the newest international textbook on all aspects of laboratory hematology. Covering both traditional and cutting-edge hematology laboratory technology this book emphasizes international recommendations for testing practices. Illustrative case studies on how technology can be used in patient diagnosis are included. Laboratory Hematology Practice is an invaluable resource for all those working in the field.
Download or read book Molecular Aspects of Hematologic Malignancies written by Michal Witt and published by Springer. This book was released on 2015-06-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.
Download or read book Hematologic Malignancies written by Manorama Bhargava and published by Springer Nature. This book was released on 2021-02-13 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail. The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book is a source of learning and a valuable read for clinical hematologists, hematopathologists, medical oncologists, residents, interns, DM Hematology students and DNB Hematology students as well.
Download or read book Laboratory Haematology written by Israel Chanarin and published by . This book was released on 1989 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neoplastic Hematopathology written by Dan Jones and published by Springer Science & Business Media. This book was released on 2010-01-24 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fulfilling the void with a Hematopathology book that integrates clinical and experimental studies with diagnostic criteria, Neoplastic Hematopathology: Experimental and Clinical Approaches provides an overview of the discipline of hematopathology that connects the field with recent advances in immunology research and current clinical practice in the treatment of lymphomas and leukemias. Designed for both trainees and specialists in pathology and hematology-oncology, Neoplastic Hematopathology: Experimental and Clinical Approaches has separate sections on laboratory techniques, diagnostic hematopathology, treatment and stem cell transplantation. Expert chapter authors address both myeloid and lymphoid tumors, and provide much needed coverage in transplant biology. A study guide highlights key chapter points, making the text suitable for boards review in hematopathology and hematology-oncology.
Download or read book Radiological Imaging in Hematological Malignancies written by Ali Guermazi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the first book’s to deal specifically with imaging of the entire spectrum of hematological malignancies. The use of the latest imaging modalities is well described, and an important aspect of the book is the role of imaging techniques in differentiating between manifestations of the underlying disease and complications of treatment. Each of the 28 chapters is written by an internationally recognized expert, making this book the most current and complete treatment of this subject available. Includes many high-quality radiological and histological illustrations. It should be of great interest to radiologists and hematologists.
Download or read book Handbook of Hematologic Malignancies written by David A. Sallman and published by Demos Medical Publishing. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: MDS/MPN With Ring Sideroblasts and Thrombocytosis
Download or read book Infections in Hematology written by Georg Maschmeyer and published by Springer. This book was released on 2014-12-13 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infections are among the most frequent complications in patients with hematological malignancies and in those undergoing high-dose chemotherapy and autologous hematopoietic stem cell transplantation. A profound knowledge on the epidemiology, diagnostic approaches, treatment modalities and prophylactic strategies is essential for the clinical management of these complications in patients who are often severely immunocompromised owing to their underlying diseases and in particular, the intensive myelosuppressive chemo and immunotherapy. This textbook provides a clinically oriented, compact and up-to-date overview on infections in hematology patients and their management. The typical pathogens to be considered in different subgroups of patients are identified and further aspects of the microbiological background are explored. Clinical, imaging, and laboratory-based diagnostic techniques are discussed and therapeutic strategies appropriate to different situations are then presented, with due attention to the pitfalls, toxicities and interactions that can arise during antimicrobial treatment. Strategies to prevent infection are also outlined, encompassing antimicrobial prophylaxis, isolation procedures, hospital hygiene, protective immunization and the use of hematopoietic growth factors.
Download or read book Oxford Handbook of Clinical Haematology written by Drew Provan and published by Oxford University Press, USA. This book was released on 2009-02-19 with total page 881 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing essential information needed in clinical practice for the diagnosis and management of patients with blood disorders, this handbook covers haematological investigations and their interpretation, and commonly used protocols.
Download or read book Rodak s Hematology E Book written by Elaine M. Keohane and published by Elsevier Health Sciences. This book was released on 2019-02-22 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Make sure you are thoroughly prepared to work in a clinical lab. Rodak’s Hematology: Clinical Principles and Applications, 6th Edition uses hundreds of full-color photomicrographs to help you understand the essentials of hematology. This new edition shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. Easy to follow and understand, this book also covers key topics including: working in a hematology lab; complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics; the parts and functions of the cell; and laboratory testing of blood cells and body fluid cells. UPDATED nearly 700 full-color illustrations and photomicrographs make it easier for you to visualize hematology concepts and show what you’ll encounter in the lab, with images appearing near their mentions in the text to minimize flipping pages back and forth. UPDATED content throughout text reflects latest information on hematology. Instructions for lab procedures include sources of possible errors along with comments. Hematology instruments are described, compared, and contrasted. Case studies in each chapter provide opportunities to apply hematology concepts to real-life scenarios. Hematology/hemostasis reference ranges are listed on the inside front and back covers for quick reference. A bulleted summary makes it easy for you to review the important points in every chapter. Learning objectives begin each chapter and indicate what you should achieve, with review questions appearing at the end. A glossary of key terms makes it easy to find and learn definitions. NEW! Additional content on cell structure and receptors helps you learn to identify these organisms. NEW! New chapter on Introduction to Hematology Malignancies provides and overview of diagnostic technology and techniques used in the lab.
