Download or read book D veloppement d outils utilisant la surveillance biologique pour valuer l exposition et les risques pour la sant written by Nolwenn Noisel and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Dans une perspective d'analyse des risques pour la santé publique, l'estimation de l'exposition revêt une importance capitale. Parmi les approches existantes d'estimation de l'exposition, l'utilisation d'outils, tels que des questionnaires alimentaires, la modélisation toxicocinétique ou les reconstructions de doses, en complément de la surveillance biologique, permet de raffiner les estimations, et ainsi, de mieux caractériser les risques pour la santé. Ces différents outils et approches ont été développés et appliqués à deux substances d'intérêt, le méthylmercure et le sélénium en raison des effets toxiques bien connus du méthylmercure, de l'interaction entre le méthylmercure et le sélénium réduisant potentiellement ces effets toxiques, et de l'existence de sources communes via la consommation de poisson. Ainsi, l'objectif général de cette thèse consistait à produire des données cinétiques et comparatives manquantes pour la validation et l'interprétation d'approches et d'outils d'évaluation de l'exposition au méthylmercure et au sélénium. Pour ce faire, l'influence du choix de la méthode d'évaluation de l'exposition au méthylmercure a été déterminée en comparant les apports quotidiens et les risques pour la santé estimés par différentes approches (évaluation directe de l'exposition par la surveillance biologique combinée à la modélisation toxicocinétique ou évaluation indirecte par questionnaire alimentaire). D'importantes différences entre ces deux approches ont été observées : les apports quotidiens de méthylmercure estimés par questionnaires sont en moyenne six fois plus élevés que ceux estimés à l'aide de surveillance biologique et modélisation. Ces deux méthodes conduisent à une appréciation des risques pour la santé divergente puisqu'avec l'approche indirecte, les doses quotidiennes estimées de méthylmercure dépassent les normes de Santé Canada pour 21 des 23 volontaires, alors qu'avec l'approche directe, seulement 2 des 23 volontaires sont susceptibles de dépasser les normes. Ces différences pourraient être dues, entre autres, à des biais de mémoire et de désirabilité lors de la complétion des questionnaires. En outre, l'étude de la distribution du sélénium dans différentes matrices biologiques suite à une exposition non alimentaire (shampoing à forte teneur en sélénium) visait, d'une part, à étudier la cinétique du sélénium provenant de cette source d'exposition et, d'autre part, à évaluer la contribution de cette source à la charge corporelle totale. Un suivi des concentrations biologiques (sang, urine, cheveux et ongles) pendant une période de 18 mois chez des volontaires exposés à une source non alimentaire de sélénium a contribué à mieux expliciter les mécanismes de transfert du sélénium du site d'absorption vers le sang (concomitance des voies régulées et non régulées). Ceci a permis de montrer que, contrairement au méthylmercure, l'utilisation des cheveux comme biomarqueur peut mener à une surestimation importante de la charge corporelle réelle en sélénium en cas de non contrôle de facteurs confondants tels que l'utilisation de shampoing contenant du sélénium. Finalement, une analyse exhaustive des données de surveillance biologique du sélénium issues de 75 études publiées dans la littérature a permis de mieux comprendre la cinétique globale du sélénium dans l'organisme humain. En particulier, elle a permis le développement d'un outil reliant les apports quotidiens et les concentrations biologiques de sélénium dans les différentes matrices à l'aide d'algorithmes mathématiques. Conséquemment, à l'aide de ces données cinétiques exprimées par un système d'équations logarithmiques et de leur représentation graphique, il est possible d'estimer les apports quotidiens chez un individu à partir de divers prélèvements biologiques, et ainsi, de faciliter la comparaison d'études de surveillance biologique du sélénium utilisant des biomarqueurs différents. L'ensemble de ces résultats de recherche montre que la méthode choisie pour évaluer l'exposition a un impact important sur les estimations des risques associés. De plus, les recherches menées ont permis de mettre en évidence que le sélénium non alimentaire ne contribue pas de façon significative à la charge corporelle totale, mais constitue un facteur de confusion pour l'estimation de la charge corporelle réelle en sélénium. Finalement, la détermination des équations et des coefficients reliant les concentrations de sélénium entre différentes matrices biologiques, à l'aide d'une vaste base de données cinétiques, concourt à mieux interpréter les résultats de surveillance biologique.

Download or read book Taking a Multisectoral One Health Approach A Tripartite Guide to Addressing Zoonotic Diseases in Countries written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2019-03-11 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2018 FAO-OIE-WHO (Tripartite) zoonoses guide, “Taking A Multisectoral, One Health Approach: A Tripartite Guide to Addressing Zoonotic Diseases in Countries” (2018 TZG) is being jointly developed to provide member countries with practical guidance on OH approaches to build national mechanisms for multisectoral coordination, communication, and collaboration to address zoonotic disease threats at the animal-human-environment interface. The 2018 TZG updates and expands on the guidance in the one previous jointly-developed, zoonoses-specific guidance document: the 2008 Tripartite “Zoonotic Diseases: A Guide to Establishing Collaboration between Animal and Human Health Sectors at the Country Level”, developed in WHO South-East Asia Region and Western Pacific Region. The 2018 TZG supports building by countries of the resilience and capacity to address emerging and endemic zoonotic diseases such as avian influenza, rabies, Ebola, and Rift Valley fever, as well as food-borne diseases and antimicrobial resistance, and to minimize their impacts on health, livelihoods, and economies. It additionally supports country efforts to implement WHO International Health Regulations (2005) and OIE international standards, to address gaps identified through external and internal health system evaluations, and to achieve targets of the Sustainable Development Goals. The 2018 TZG provides relevant country ministries and agencies with lessons learned and good practices identified from country-level experiences in taking OH approaches for preparedness, prevention, detection and response to zoonotic disease threats, and provides guidance on multisectoral communication, coordination, and collaboration. It informs on regional and country-level OH activities and relevant unisectoral and multisectoral tools available for countries to use.

Download or read book New Strategies in Locust Control written by S. Krall and published by Birkhäuser. This book was released on 2012-12-06 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late eighties large-scale control operations were carried out to control a major desert locust upsurge in Africa. For the first time since the banning of organochlorine pesticides these operations relied mainly on non-persistent pesticides such as organophosphates and pyrethroids. The amount of pesticides sprayed and the area covered were probably the highest in the history of locust control and raised criticism with respect to efficacy, economic viability and environmental impact. As a consequence, applied research into the problem was intensified, both at the national and the international level, with the goal of finding new and environmentally sound approaches and solutions to locust and grasshopper control. Emphasis was laid on developing new control agents and techniques.

Download or read book Gender Matters written by Dennis van der Veur and published by Council of Europe. This book was released on 2007-01-01 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: "'Gender Matters' is a manual aimed to assist educators and youth leaders work on issues of gender and gender-based violence with young people. This publication presents theoretical information, methods and resources for education and training activities, along with concrete exercises that users can put into practice in their daily work. Violence is a serious issue which directly affects the lives of many young people. It often results in lasting damage to their well-being and integrity, putting even their lives at risk. Gender-based violence, including violence against women, remains a key human rights challenge in contemporary Europe and in the world. Working with young people on human rights education is one way of preventing gender-based violence from occurring. By raising awareness on why and how it manifests and exploring its impact on people and in society, gender-based violence will no longer go undetected. Gender really does matter, to women, to men, to young people - to all of us. This manual serves to explore these human rights issues and act upon them."--Book jacket.

Download or read book Suicide a Study in Sociology written by Émile Durkheim and published by Glencoe, Ill. : Free Press. This book was released on 1951 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translated from French, this classic provides readers with an understanding of the impetus for suicide and its psychological impact on the victim, family, and society.

Download or read book Clinical Management of Patients with Viral Haemorrhagic Fever written by World Health Organization and published by World Health Organization. This book was released on 2016-05-03 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in March 2014 under the title "Clinical management of patients with viral haemorrhagic fever: a pocket guide for front-line health workers: interim emergency guidance for West Africa".

Download or read book Basic Technics in Ecological Farming Techniques de Base en Agriculture Biologique Grunds tzliche Verfahren der kologischen Landwirtschaft Le Maintien de la Fertilit des Sols The Maintenance of Soil Fertility Die Erhaltung der Bodenfruchtbarkeit written by Stuart Hill and published by Birkhäuser. This book was released on 2013-12-14 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Madness and Social Representations written by Denise Jodelet and published by Univ of California Press. This book was released on 1991-01-01 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: A striking account of a colony for the mentally ill that forces a reconsideration of madness in society. What happens when the mentally ill are not isolated from society but are instead welcomed into it and invited to take a place in the fabric of the community? Are fear and rejection replaced by the understanding and sympathy often engendered by familiarity? Or are the barriers between the sane and the mad only strengthened? We have experienced a taste of this scenario in the U.S. in the last decade with the new emphasis on de-institutionalization, but Denise Jodelet takes us to an extraordinary community in France where the mentally ill have assumed a visible and prominent role for more than seventy years. The small French town of Ainay-le-Ch�teau and its environs are the site of a "family colony" for men, established in 1900. Here the patients ("lodgers") live with ordinary families ("foster parents"), hold jobs, and are free to move about the countryside. Jodelet's chronicle of daily life in the colony is made rich and vivid by extensive ethnographic material as she unravels a complex set of relationships, ultimately finding that while some of the barriers between the "other" and the larger society have been overcome, new ones have arisen in their place. This unique social experiment provides invaluable social and cultural insights, illuminating many fundamental issues in psychology, psychiatry, and sociology.

Download or read book What is the Code of Conduct for Responsible Fisheries written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2001 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: The actual Code of conduct is also available (1996) (ISBN 9251038341).

Download or read book The World Problem of Salmonellosis written by E. van Oye and published by . This book was released on 2014-09-01 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Computers and Games for Mental Health and Well Being written by Yasser Khazaal and published by Frontiers Media SA. This book was released on 2018-07-12 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen important developments in the computer and game industry, including the emergence of the concept of serious games. It is hypothesized that tools such as games, virtual reality, or applications for smartphones may foster learning, enhance motivation, promote behavioral change, support psychotherapy, favor empowerment, and improve some cognitive functions. Computers and games may create supports for training or help people with cognitive, emotional, or behavioral change. Games take various formats, from board games to informatics to games with interactive rules of play. Similarly, computer tools may vary widely in format, from self-help or assisted computerized training to virtual reality or applications for smartphones. Some tools that may be helpful for mental health were specifically designed for that goal, whereas others were not. Gamification of computer-related products and games with a numeric format tend to reduce the gap between games and computers tools and increase the conceptual synergy in such fields. Games and computer design share an opportunity for creativity and innovation to help create, specifically design, and assess preventive or therapeutic tools. Computers and games share a design conception that allows innovative approaches to overcome barriers of the real world by creating their own rules. Yet, despite the potential interest in such tools to improve treatment of mental disorders and to help prevent them, the field remains understudied and information is under-disseminated in clinical practice. Some studies have shown, however, that there is potential interest and acceptability of tools that support various vehicles, rationales, objectives, and formats. These tools include traditional games (e.g., chess games), popular electronic games, board games, computer-based interventions specifically designed for psychotherapy or cognitive training, virtual reality, apps for smartphones, and so forth. Computers and games may offer a true opportunity to develop, assess, and disseminate new prevention and treatment tools for mental health and well-being. Currently, there is a strong need for state-of-the-art information to answer questions such as the following: Why develop such tools for mental health and well-being? What are the potential additions to traditional treatments? What are the best strategies or formats to improve the possible impact of these tools? Are such tools useful as a first treatment step? What is the potential of a hybrid model of care that combines traditional approaches with games and/or computers as tools? What games and applications have already been designed and studied? What is the evidence from previous studies? How can such tools be successfully designed for mental health and well-being? What is rewarding or attractive for patients in using such treatments? What are the worldwide developments in the field? Are some protocols under development? What are the barriers and challenges related to such developments? How can these tools be assessed, and how can the way that they work, and for whom, be measured? Are the potential benefits of such products specific, or can these additions be attributed to nonspecific factors? What are the users’ views on such tools? What are the possible links between such tools and social networks? Is there a gap between evidence-based results and market development? Are there any quality challenges? What future developments and studies are needed in the field?

Download or read book Environmental Code of Practice for Metal Mines written by Canada. Environment Canada and published by . This book was released on 2009 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes operational activities and associated environmental concerns of this industrial sector. The document applies to the complete life cycle of mining, from exploration to mine closure, and environmental management practices are recommended to mitigate the identified environmental concerns. The recommended practices in the Code include the development and implementation of environmental management tools, the management of wastewater and mining wastes, and the prevention and control of environmental releases to air, water and land. The Code of Practice will be adopted by Environment Canada and others as a guidance document that recommends environmental protection practices for the mine life cycle. The Code applies specifically to metal mines but will provide useful guidance for all sectors of the mining industry.

Download or read book Handbook of Organizational Behavior written by Robert T. Golembiewski and published by CRC Press. This book was released on 1993 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents organizational behaviour from a marketing perspective, offering examinations of standard topics, areas that deserve more attention and emerging issues that will affect the future of OB. Subjects that contribute to expanding demand for OB theory, approaches and results are explored.

Download or read book Biodiversity and Sustainable Development written by Rabindra Nath Pati and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Papers presented at the First Global Summit on Sustainable Development and Biodiversity, held at Raipur during 7-9 February 2009.

Download or read book Evolution of Awareness written by Kia Marlene and published by . This book was released on 2022-03-08 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolution of Awareness, the debut poetry collection from Kia Marlene, is a book about a spiritual journey towards enlightenment. The collection consists of 6 chapters, titled "The Egg," "The Caterpillar," "Intermission (heartbreak&love)," "The Cocoon," "The Butterfly," and a chapter titled "Knock Knock." Through numerous poems this book outlines various thoughts, questions and eventual answers concerning our collective greater purpose in life, self love, consciousness, and personhood. The author intends for this book to help broaden the reader's general perception, view of their environment, awareness, and sense of self.

Download or read book Traditional Mediterranean Architecture written by Amin Maalouf and published by . This book was released on 2002 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Proceedings of the First International Congress of Radiation Protection written by and published by . This book was released on 1968 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: