Download or read book Isolation and Preliminary Characterization of Temperature sensitive Mutants of Herpes Simplex Virus Type 1 written by Mark Michael Priemer and published by . This book was released on 1980 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Preliminary Characterization of Temperature sensitive Mutants of Herpes Simples Virus Type 1 written by Jasmine Ilga.* Daksis and published by . This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Isolation and Preliminary Characterization of Temperature sensitive Mutants of Vesicular Stomatitis Virus written by Kai-Yiu Paul Wong and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Identification of HSV type 1 Temperature Sensitive Mutants Useful in the Characterization of the Primary Round of Viral Specific DNA Synthesis written by Linda Diane Coogle and published by . This book was released on 1985 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Isolation and Partial Characterizations of Six Temperature Sensitive Mutants of Herpes Simplex Virus Type 2 written by Janice R. Connor and published by . This book was released on 1977 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genetic Characterization of a Delayed Host Shutoff Temperature Sensitive Mutant of Herpes Simplex Virus Type I written by Edward Francis.* Arko and published by . This book was released on 1989 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genetic and Biochemical Studies with Temperature sensitive Mutants of Herpes Simplex Virus Type 1 written by J. A. V. Coates and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Isolation and Characterization of Temperature sensitive Mutants of Foot and mouth disease Virus FMDV written by Daphna Manor and published by . This book was released on 1975 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Current Topics in Microbiology and Immunology Ergebnisse der Mikrobiologie und Immunit tsforschung written by W. Arber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: The processes involved in herpesvirus replication, latency, and oncogenic transformation, have, in general, been rather poorly defined. A primary reason for this is the size and complexity of the herpesvirus genome. Undoubtedly, a better understanding of the functions of the viral genome in infected and transformed cells will be achieved through studies with temperature-sensitive (ts) mutants of herpesviruses since, theoretically, any essential gene function can be affected by mutants of this type. A. The Herpesviruses A consideration of the genetic analysis of members of the herpesvirus group necessitates a description, albeit brief, of the properties of the group and, most importantly, of their genetic material. The herpesviruses comprise a group of relatively large (100-150 nm), enveloped viruses. The envelope surrounds an icosahedral capsid enclosing a core which contains double stranded DNA (ROIZMAN, 1969). The group is thus defined on the basis of a common virion morphology. In addition to a common structure, members of the group share a number of biological properties such as a similar replicative cycle, the ability to cause latent and chronic infections, and the ability to induce antigenic modifications of infected cell membranes. Several herpes viruses have been associated recently with malignancies in man and animals (KLEIN, 1972). Herpesviruses are ubiquitous and have been described in over 30 different species (HUNT and MELENDEZ, 1969; WILDY, 1971; FARLEY et aI. , 1972; KAZAMA and SCHORNSTEIN, 1972; NAHMIAS et aI. , 1972; ROlZMAN et aI. , 1973). Their widespread occurrence in nature suggests a common ancestor.

Download or read book Fields Virology Fundamentals written by Peter M Howley and published by Lippincott Williams & Wilkins. This book was released on 2023-02-14 with total page 1999 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families.

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1974 with total page 1260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1979 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Download or read book Regulation of Gene Expression in Animal Viruses written by Luis Carrasco and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viruses, being obligatory parasites of their host cells, rely on a vast supply of cellular components for their replication, regardless of whether infection leads to cell death or to the state of persistence. Animal viruses are providing scientists with relatively simple models to study the molecular biology of genome replication and gene expression. Whereas viruses use, in general, pathways of macromolecular biosynthesis common to the host cell, they have a cunning ability to adopt unusual mechanisms of gene expression and gene replication, provided these special pathways offer an advantage in competition for cellular resources. Any study of viral gene expression and replication is likely to lead also to new insights in cellular metabolism. The discoveries of cis-acting regulatory elements in transcription, the phenomenon of splicing of pre mRNA, and cap-dependent and cap-independent initiation of translation may be cited as examples. In addition, animal virus genomes contain elements and encode proteins that are very useful for the design of vectors for gene cloning and expression in mammalian cells. Apart from the basic interest in their biology, viruses have gained notoriety, of course, because they are pathogens. Human animal viruses may cause diseases ranging from the deadly (AIDS) to the benign (common cold). All studies on animal viruses potentially lead to the development of tools for their control, be it through prevention by immunization or treatment with antiviral drugs. Finally, viruses have yielded invaluable reagents in molecular biology as, for example, the vaccinia virus vector for the expression of foreign genes.

Download or read book Current Bibliography of Epidemiology written by and published by . This book was released on 1972 with total page 1346 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Poxviruses written by Richard W. Moyer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this volume is to highlight some current areas of poxvirus research which are likely to be particularly fruitful in the upcoming few years. The first chapter, by Drs. Condit and Niles, discusses poxvirus genetics. Work in this area has provided mutants, produced practical procedures to simplify the manipulation of viral genes, and generated information about the molecular architecture and organization of genes characteristic of pox viruses. One of the most intensively studied regions of the viral genome is the HindIII D region of vaccinia, in which a combination of classical and molecular genetic analysis of the region has been particularly revealing. Within this region are open reading frames, some of which are expressed early and others late, organized in a fashion which is now known to be typical of these viruses. Other studies, related to temperature sensitive, drug resistant, and drug dependent mutants, are also discussed. Each of the other reviews included in this volume summarizes areas of research which have depended heavily on the genetics of the system. The intracellular site of a poxvirus infection is mostly, if not exclusively, limited to the cytoplasm which dictates several interesting biological ramifications. For example, poxvirus transcription must occur in the cytoplasm, rather than in the nucleus. The virus copes with this situation by incorporating into the virion the enzymatic machinery necessary to initiate transcription from input virus.

Download or read book Current Advances in Genetics written by and published by . This book was released on 1980 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt: