Download or read book Isolation and Genetic Characterization of Temperature sensitive Mutants of the Concan Subtype of Vesicular Stomatitis Virus written by Alfred Dean Byrd and published by . This book was released on 1983 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Rhabdoviruses written by Robert R. Wagner and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: The viruses of the family Rhabdoviridae have an exceedingly broad host range and are widely distributed throughout the animal and plant king doms. Animal rhabdoviruses infect and often cause disease in insects, fish, and mammals, including man. The prototype rhabdovirus, vesicular stomatitis virus !VSV), has been extensively studied and provides perhaps the best model system for studying negative-strand viruses. The popularity of VSV as a model system is to a considerable extent due to its relative simplicity and to its rapid growth, generally to high titer, in many cell types ranging from yeast to human. The nucleocapsids of these viruses also carry transcriptional and replicative functions that are expressed in cell-free systems. The first RNA-dependent RNA poly merase was described in VSV and its G protein provided an early model system for studying the synthesis, processing, and membrane insertion of mammalian glycoproteins. VSV is also highly cytopathogenic and has been studied quite extensively for its capacity to kill cells and to shut off cellular macromolecular synthesis. Even earlier, VSV was discovered to be highly susceptible to the action of interferons and has served ever since as a means for quantitating the activity of interferons. To my way of thinking, the spark that ignited the explosion of re search in this field was struck at the First International Colloquium on Rhabdoviruses, attended by 30 or so participants in Roscoff, France, in June 1972.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1985 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1985-05 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comprehensive Dissertation Index written by and published by . This book was released on 1989 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book American Doctoral Dissertations written by and published by . This book was released on 1984 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetics Abstracts written by and published by . This book was released on 1989 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Isolation and Preliminary Characterization of Temperature sensitive Mutants of Vesicular Stomatitis Virus written by Kai-Yiu Paul Wong and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Translocator Protein TSPO written by Giovanni Natile and published by MDPI. This book was released on 2018-03-05 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Translocator Protein (TSPO)" that was published in IJMS
Download or read book Viruses Plagues and History written by Michael B. A. Oldstone and published by Oxford University Press, USA. This book was released on 2020 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Here, my previous edition of Viruses, Plagues, & History is updated to reflect both progress and disappointment since that publication. This edition describes newcomers to the range of human infections, specifically, plagues that play important roles in this 21st century. The first is Middle East Respiratory Syndrome (MERS), an infection related to Sudden Acute Respiratory Syndrome (SARS). SARS was the first new-found plague of this century. Zika virus, which is similar to yellow fever virus in being transmitted by mosquitos, is another of the recent scourges. Zika appearing for the first time in the Americas is associated with birth defects and a paralytic condition in adults. Lastly, illness due to hepatitis viruses were observed prominently during the second World War initially associated with blood transfusions and vaccine inoculations. Since then, hepatitis virus infections have afflicted millions of individuals, in some leading to an acute fulminating liver disease or more often to a life-long persistent infection. A subset of those infected has developed liver cancer. However, in a triumph of medical treatments for infectious diseases, pharmaceuticals have been developed whose use virtually eliminates such maladies. For example, Hepatitis C virus infection has been eliminated from almost all (>97%) of its victims. This incredible result was the by-product of basic research in virology as well as cell and molecular biology during which intelligent drugs were designed to block events in the hepatitis virus life-cycle"--
Download or read book Pharmaceutical Biotechnology written by Carlos A. Guzmán and published by Springer. This book was released on 2012-03-14 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to dramatically expand the scope of preventive medicine beyond the infectious disease arena into broad applications in immune and cancer treatment, as exemplified by anti-EGFR receptors antibodies for the treatment of breast cancer. The exponential growth in biologicals such as engineered proteins and vaccines has been boosted by unprecedented scientific breakthroughs made in the past decades culminating in an in-depth fundamental understanding of the scientific underpinnings of immune mechanisms together with knowledge of protein and peptide scaffolds that can be deliberately manipulated. This has in turn led to new strategies and processes. Deciphering the human, mammalian and numerous pathogens’ genomes provides opportunities that never before have been available—identification of discrete antigens (genomes and antigenomes) that lend themselves to considerably improved antigens and monoclonal antibodies, which with more sophisticated engineered adjuvants and agonists of pattern recognition receptors present in immune cells, deliver unprecedented safety and efficacy. Technological development such a nanobiotechnologies (dendrimers, nanobodies and fullerenes), biological particles (viral-like particles and bacterial ghosts) and innovative vectors (replication-competent attenuated, replication-incompetent recombinant and defective helper-dependent vectors) fulfill a broad range of cutting-edge research, drug discovery and delivery applications. Most recent examples of breakthrough biologicals include the human papilloma virus vaccine (HPV, prevention of women genital cancer) and the multivalent Pneumoccocal vaccines, which has virtually eradicated in some populations a most prevalent bacterial ear infection (i.e., otitis media). It is expected that in the years to come similar success will be obtained in the development of vaccines for diseases which still represent major threats for human health, such as AIDS, as well as for the generation of improved vaccines against diseases like pandemic flu for which vaccines are currently available. Furthermore, advances in comparative immunology and innate immunity revealed opportunities for innovative strategies for ever smaller biologicals and vaccines derived from species such as llama and sharks, which carry tremendous potential for innovative biologicals already in development stages in many pharmaceutical companies. Such recent discoveries and knowledge exploitations hold the promise for breakthrough biologicals, with the coming decade. Finally, this book caters to individuals not directly engaged in the pharmaceutical drug discovery process via a chapter outlining discovery, preclinical development, clinical development and translational medicine issues that are critical the drug development process. The authors and editors hope that this compilation of reviews will help readers rapidly and completely update knowledge and understanding of the frontiers in pharmaceutical biotechnologies.
Download or read book Diterpenoids written by Brandon Jones and published by Nova Science Publishers. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diterpenoids are chemical compounds containing 20 carbon atoms and belong to the terpenoid class. They derive from geranylgeraniol, a C20 precursor, have a C20H32 basic structure, and are composed of four isoprene units. These features make diterpenoids different from simple terpenes, which possess only 10 carbon atoms. A diterpenoid molecule may also include alcohol, phenol, aldehyde, cheton, or acidic functional groups. These compounds are highly lipophilic, odorless, and may possess strong flavours. They are found mainly in fungi and in resins of higher-order plants, as typical products of plant metabolism. This book examines the types, functions and provides new research on diterpenoids.
Download or read book Viral Pandemics written by Rae-Ellen W. Kavey and published by Routledge. This book was released on 2020-09-28 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a public health practitioner and a medical historian, Viral Pandemics explores the terrifying world of viruses as the cause of all acute pandemics since 1900, including the COVID-19 pandemic. The book illuminates the critical dual roles of viral biology and increasing global interconnectedness that have resulted in an escalating pandemic spiral. Viral Pandemics is the first book to focus exclusively on pandemics caused by viruses and the first to report the COVID-19 pandemic. In each chapter, the historiographic narrative follows the path of the virus from its original detection through its first appearance as the cause of disease, to its emergence as an explosive pandemic. Scientific information is presented in an accessible, straightforward style in compelling narratives that introduce the extraordinary universe of diverse, opportunistic viruses whose remarkable capacities make them formidable adversaries. The book makes it clear that global viral disease challenges are a persistent reality with the potential to cause catastrophic loss of life and major social and economic damage. A summary chapter draws together lessons learned and develops a proposed multidisciplinary global response. Viral Pandemics is the only book that provides a complete historical narrative focused on viral pandemics. This comprehensive survey is designed for students and scholars in biology, epidemiology, public health, global history and the history of medicine, as well as general readers interested in the science of pandemics.
Download or read book Contemporary Oral Medicine written by Camile S. Farah and published by Springer. This book was released on 2019-03-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, written by world authorities in the field, is a comprehensive, up-to-date guide to the specialty of Oral Medicine, which is concerned with the diagnosis, prevention, and predominantly non-surgical management of medically related disorders and conditions affecting the oral and maxillofacial region. The pathophysiology, clinical presentation, diagnostic evaluation, and treatment of all relevant diseases and disorders are described with the aid of a wealth of clinical cases and illustrations that enable the reader to appreciate the diversity and potential complexity of Oral Medicine. In addition to the wide-ranging coverage of oral conditions, separate sections are devoted to bone and cutaneous pathology and to orofacial pain and its management, in addition to dental sleep medicine. The clinician who treats Oral Medicine patients will find this book to be an excellent aid to optimal management grounded in a sound knowledge of basic science and the dental and medical aspects of each disorder. In addition, it will serve as an outstanding textbook for undergraduate and postgraduate students.
Download or read book First Aid for the USMLE Step 1 written by Vikas Bhushan and published by McGraw Hill Professional. This book was released on 2007-01-09 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: The #1 Review for the USMLE Step 1 - written by students who aced the boards! 900+ must-know facts and mnemonics organized by organ systems and general principles 24 pages of color photos like those on the exam 100+ clinical vignettes Brand new Pathology chapter and totally revised Behavioral Science chapter The famous “First Aid Ratings” - 300+ medical test prep resources rated by students Updated exam preparation guide with advice from Step 1 veterans Strategies that maximize your study time and deliver the results you want
Download or read book First Aid for the USMLE Step 1 2020 Thirtieth edition written by Tao Le and published by McGraw-Hill Education / Medical. This book was released on 2020-01-06 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. EXCEL ON THE USMLE® STEP 1 WITH HELP FROM THE WORLD’S MOST POPULAR MEDICAL REVIEW BOOK! Trust First AidTM to help you score your highest on this high-stakes exam Written by students who excelled on the Step 1 exam and reviewed by top faculty for accuracy, this indispensable guide provides you with a blueprint of all the content you’re likely to find on the exam. Packed with insider advice for students from students, First Aid for the USMLE® Step 1 2020 will help maximize your study time. Features A complete framework for USMLE Step 1 preparation 1,300+ must-know topics with mnemonics to focus your study 1,000+ color photos and illustrations to help you visualize processes, disorders, and clinical findings Rapid Review section presents high-yield tables associating diseases with their clinical findings, treatments, and pathophysiology Updated every year to ensure all content is relevant and high-yield, reflecting the most current USMLE blueprint
Download or read book Characterization of a Temperature sensitive Mutant of Vesicular Stomatitis Virus written by Michael S. Nickels and published by . This book was released on 1994 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
