Download or read book Primary Immunodeficiency Diseases written by Nima Rezaei and published by Springer Science & Business Media. This book was released on 2008-08-06 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primary immunodeficiency diseases (PID) are a group of disorders involving defects in one or more components of the immune system, and are characterized by an increased incidence of infections, autoimmunity, and malignancies. Although PID seem to be rare, the number of patients diagnosed has increased in recent years, and more than 150 different forms of PID have been identified. Nevertheless, because of inadequate medical awareness, a significant number of patients with PID are either not recognized as having a PID or are not diagnosed as early as they should be. Such delays lead to a substantial increase in morbidity and mortality among affected individuals. Our understanding of PID is improving rapidly, which will hopefully lead to more accurate diagnosis and efficient disease management. This book contains the most recent advances in the field, as well as a concise and structured review of previously identified PID. Although the book’s primary focus is on practical diagnosis and management, the pathophysiology of PID is also discussed. This book is a comprehensive yet manageable resource for physicians and nurses wishing to learn more about PID, as well as a useful tool for both doctors-in-training and specialists in clinical decision-making and treatment planning.

Download or read book Primary and Secondary Immunodeficiency written by Jonathan A. Bernstein and published by Springer Nature. This book was released on 2021-01-28 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases. Chapters begin with a comprehensive overview of immunodeficiencies to ground the reader in practical knowledge of the field and these complex conditions. Chapters cover B lymphocyte immunodeficiency, T cell immunodeficiency, immune dysregulation syndromes, and innate immune defects. They discuss a range of treatment options including gene therapy or bone marrow transplant. The book continues with a discussion on secondary immunodeficiencies and their treatment. Each chapter was written by authors with expertise related to different immunodeficiency disorders and provide a succinct overview of pathomechanisms, diagnosis, and treatment of a specific condition. Primary and Secondary Immunodeficiency will be an excellent resource for practicing allergists, hematologists, clinical immunologists, fellows, residents, and other clinicians who work with immunodeficiency patients.

Download or read book Nutrition Support for Infants and Children at Risk written by Richard J. Cooke and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adequate nutrition is especially important during infancy and childhood, where even short periods of malnutrition have long-lasting effects on growth, development and health in adult life. There are several high-risk scenarios for the development of malnutrition, which are the focus of the current publication: Atopic diseases, gastrointestinal disorders, and preterm delivery. For the pediatric allergist it is important to understand the mechanisms regulating IgE responses to food proteins since they may also be the earliest markers for the atopic march. As breastfeeding seems to have only limited effects regarding the atopic march, other measures to modulate infantile immune responses have to be taken, including the use of hypoallergenic formulae or the addition of probiotics or prebiotics to infant formulae. The second part of this book highlights the functional properties of nutrition with regard to diseases of the gastrointestinal tract and the ensuing chronic alterations of gastrointestinal function. Topics addressed include the molecular basis of some diseases, main causes of and nutritional measures in chronic enteropathy, including the role of parenteral and enteral nutrition, stressed mucosa and the role of nutrition in cholestatic liver disease. Nowadays, smaller and more immature infants are surviving - but the smaller the infant, the greater the accrued deficit as nutritional needs change with advancing maturity, and one formulation may not meet all requirements. Furthermore, there are no sensitive, accurate and precise measures of nutritional outcome. The net effect of these uncertainties is that all very-low-birth-weight infants are growth retarded at hospital discharge. Strategies for improving growth in these high-risk infants are at the center of the last part of this publication.

Download or read book Cellular Primary Immunodeficiencies written by Mario Milco D'Elios and published by Springer Nature. This book was released on 2021-06-10 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the series Rare Diseases of the Immune System presents detailed state of the art knowledge on the cellular primary immunodeficiencies; it includes extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the T cell immunological synapse. Readers will find comprehensive, in-depth descriptions of novel cellular PID genes and related clinical applications, mucosal T cells, and the various clinical phenotypes of cellular PIDs. Cellular Primary Immunodeficiencies will be of high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD, Master and PhD students.

Download or read book Stiehm s Immune Deficiencies written by Kathleen E. Sullivan and published by Academic Press. This book was released on 2020-05-23 with total page 1334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stiehm’s Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy. Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians Fills an increasingly deep gap in the information available to clinicians Presents both clinical management and scientific advances for immune deficiencies Provides a primary resource for physicians in the field of immunodeficiencies Includes website access to a range of videos relevant to the topics discussed

Download or read book Allergy and Clinical Immunology written by Hugh A. Sampson and published by John Wiley & Sons. This book was released on 2015-05-06 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mount Sinai Expert Guides: Allergy and Clinical Immunology will provide trainees in allergy and immunology with an extremely clinical and accessible handbook covering the major disorders and symptoms, their diagnosis and clinical management. Perfect as a point-of-care resource on the hospital wards and also as a refresher for board exam preparation, the focus throughout is on providing rapid reference, essential information on each disorder to allow for quick, easy browsing and assimilation of the must-know information. All chapters follow a consistent template including the following features: An opening bottom-line/key points section Classification, pathogenesis and prevention of disorder Evidence-based diagnosis, including relevant algorithms, laboratory and imaging tests, and potential pitfalls when diagnosing a patient Disease management including commonly used medications with dosages, management algorithms and how to prevent complications How to manage special populations, ie, in pregnancy, children and the elderly The very latest evidence-based results, major society guidelines and key external sources to consult In addition, the book comes with a companion website housing extra features such as case studies with related questions for self-assessment, key patient advice and ICD codes. Each guide also has its own mobile app available for purchase, allowing you rapid access to the key features wherever you may be. If you're specialising in allergy and immunology and require concise, practical and clinical guidance from one of the world's leading institutions in this field, then this is the perfect book for you. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.

Download or read book Primary Immunodeficiency Diseases written by Hans D. Ochs and published by . This book was released on 2007 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Primary Immunodeficiency Diseases presents discussions of gene identification, mutation detection, and clinical and research applications for over 100 genetic immune disorders--disorders featuring an increased susceptibility to infections and, in certain conditions, an icreased rate of malignancies and autoimmune disorders. Since the publication of the first edition, a flurry of new disease entities has been defined and new treatment regimens have been introduced, the most spectacular being successful treatment by gene therapy for two genotypes of combined immunodeficiency. The first edition marked a historic turning point in the field of immunodeficiencies, demonstrating that many of the disorders of the immune systam could be understood at a molecular level. This new edition can proudly document the tremendous pace of progress in dissecting the complex immunologic networks responsible for protecting individuals from these disorders.

Download or read book Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases written by Richard K. Burt and published by CRC Press. This book was released on 2021-11-17 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the global progress in medical and scientific research toward converting traditionally chronic autoimmune diseases into a drug-free reversible illness using hematopoietic stem cell transplantation (HSCT) and other cellular therapies such as T regulatory cells (Treg), mesenchymal stromal/stem cells, and chimeric antigen receptor T (CAR T) cells in order to reintroduce sustained immune tolerance. This title provides information on different types of stem cells and immune cells; post-transplant immune regeneration; cellular regulatory requirements; ethical and economic considerations; and the advantages and disadvantages of HSCT in the treatment of a variety of autoimmune diseases versus current conventional treatments. Arranged by disease, the text provides a comprehensive guide to HSCT for all types of autoimmune/immune disorders including monogenetic autoimmune diseases; autoimmune aplastic anemia; neurologic immune diseases including multiple sclerosis, chronic inflammatory demyelinating polyneuropathy, neuromyelitis optica, and stiff person syndrome; rheumatologic diseases such as systemic sclerosis and systemic lupus erythematosus; dermatologic diseases such as pemphigus; gastrointestinal disorders such as Crohn’s disease and celiac disease; and immune-mediated endocrinologic disease type I diabetes mellitus. Guidance is provided on the transplantation technique, cell collection and processing, conditioning regimens, infections, and early and late complications. Key Features Outlines therapies and techniques for HSCT for autoimmune diseases Discusses the advantages of HSCT over conventional therapies Reviews the entire process of stem cell therapy from harvest and ethics to indications, efficacy, and regulatory oversight

Download or read book Immune Mediated Diseases written by Michael R. Shurin and published by Springer Science & Business Media. This book was released on 2007-07-25 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes contributions from the speakers of the Second IMD Congress (September 10-15, 2007; Moscow, Russia) who were eager to share some of the academic and clinical enthusiasm that defines the IMD meetings. The goal of the International Immune-Mediated Diseases: From Theory to Therapy (IMD) Congress is to bring the world’s best immunologists and clinicians to Moscow.

Download or read book Immunoendocrinology Scientific and Clinical Aspects written by George S. Eisenbarth and published by Springer Science & Business Media. This book was released on 2010-12-13 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunoendocrinology is a rapidly developing field of research that seeks to understand the intersection of the immune and endocrine systems. Immunoendocrinology: Scientific and Clinical Aspects explores in detail the current knowledge of immunoendocrinology, namely endocrine disorders produced by disorders of immune function. Chapters cover both basic pathophysiology informed by studies of animal models as well as current understanding of multiple related clinical diseases—their pathophysiology, diagnosis, and therapy. Immunoendocrinology: Scientific and Clinical Aspects captures the central role of immunoendocrinologic processes in the pathogenesis of not only type 1 diabetes but in a range of other autoimmune and endocrine disorders.

Download or read book Advances in Immunology written by Frederick W. Alt and published by Academic Press. This book was released on 2007-10-01 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Download or read book Practices of Inter Parliamentary Coordination in International Politics written by Ben Crum and published by ECPR Press. This book was released on 2014-09-01 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parliaments risk becoming the main losers of internationalisation; a process that privileges executives and experts. Still, parliamentarians have developed a range of responses to catch up with international decision-making: they coordinate their actions with other parliamentarians; engage in international parliamentary forums; and some even opt to pursue political careers at the supranational level, such as in the European Parliament. This volume provides a thorough empirical examination of how an internationalising context drives parliamentarians to engage in inter-parliamentary coordination; how it affects their power positions vis-à-vis executive actors; among themselves; and in society in general. Furthermore, building upon these empirical insights, the book assesses whether parliamentary democracy can remain sustainable under these changing conditions. Indeed, if parliaments are, and remain, central to our understanding of modern democracy, it is of crucial importance to track their responses to internationalisation, the fragmentation of political sovereignty, and the proliferation of multilevel politics.

Download or read book Stocker and Dehner s Pediatric Pathology written by Aliya N Husain and published by Lippincott Williams & Wilkins. This book was released on 2021-04-06 with total page 4583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually all aspects of the pathology in children are unique in pathogenesis and histogenesis from the moment of conception to adolescence whose range includes developmental anomalies to dysembryonic neoplasms. Stocker and Dehner’s Pediatric Pathology provides encyclopedic but very usable coverage of this complex subspecialty, detailing all major aspects of the pathologic anatomy of childhood disorders ranging from chromosomal syndromes and infections to forensic pathology. Upholding the standard of excellence established in previous editions, this thoroughly updated Fifth Edition offers the in-depth, richly illustrated guidance you need to confidently evaluate and dependably report your findings.

Download or read book Pediatric Immunology written by Nima Rezaei and published by Springer Nature. This book was released on 2019-10-08 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprises a collection of categorized case-based questions, directed and meticulously selected to cover the most common and most important aspects of immunodeficiency diseases. Immunodeficiency disorders of infancy and childhood such as antibody deficiencies, phagocyte defects and defects in innate immunity are addressed among others. Each chapters starts with a brief of the initial presentation and lab data of the patient, followed by a series of 5-6 multiple choice questions (MCQs), leading the reader to the diagnosis and best of practice in a step-wise manner. This MCQ format along with precise, yet detailed answer ensures a quick, case-based, reality learning to the reader. This comprehensive MCQ series, is an essential reading material that a pediatric clinician, hematologist, immunologist, transplant specialist, or pulmonologist, can not afford to miss.

Download or read book Pediatric Allergy written by Donald Y. M. Leung and published by Elsevier Health Sciences. This book was released on 2020-10-19 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: With complete, concise coverage of prevention, indications, diagnosis, and treatment, Pediatric Allergy, 4th Edition, is your go-to resource for current, clinically-focused content in the rapidly changing field of allergies and immune-mediated diseases in children. This highly regarded reference fully covers immunology and origins of allergy, growth and development, pregnancy, infancy, and early, middle, and late childhood—all with a new, practical, clinical focus. You’ll find authoritative coverage of the full range of allergies in pediatric patients, from asthma and other common conditions to rare or uncommon allergies, providing a one-stop resource for clinicians across specialties who care for children. Focuses on the clinical application of science to the bedside, including clinical pearls discussing best practice approaches and guidelines. Integrates the latest research on the origins of allergy in early life, including pregnancy, the neonate, and infants. Includes new, evidence-based management guidelines for various diseases, including food allergy, atopic dermatitis, asthma and immunodeficiency. Provides new content on the prevention of allergies; asthma, eczema, and food allergies in young children; and extensive current guidelines and new therapies. Offers up-to-date information on key areas such as food challenges, skin testing, IgE diagnostic labs, immunotherapy, clinical immunology diagnostic testing, molecular diagnostics, and lung function testing. Highlights current guidance from a new team of leading experts with 150 anatomic schematics, clinical photos, and algorithms—many new to this edition. Covers gene therapy, stem-cell therapy, and a host of immunodeficiency diseases found in children with allergies. Discusses targeted biologics for severe allergic diseases, defects of innate immunity, rheumatic diseases of childhood, and inflammatory disorders.

Download or read book Creating Awareness for Primary Immunodeficiencies in the Southeast and East Asia Regions written by Intan Hakimah Ismail and published by Frontiers Media SA. This book was released on 2022-06-02 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Accelerate Model Training with PyTorch 2 X written by Maicon Melo Alves and published by Packt Publishing Ltd. This book was released on 2024-04-30 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dramatically accelerate the building process of complex models using PyTorch to extract the best performance from any computing environment Key Features Reduce the model-building time by applying optimization techniques and approaches Harness the computing power of multiple devices and machines to boost the training process Focus on model quality by quickly evaluating different model configurations Purchase of the print or Kindle book includes a free PDF eBook Book DescriptionThis book, written by an HPC expert with over 25 years of experience, guides you through enhancing model training performance using PyTorch. Here you’ll learn how model complexity impacts training time and discover performance tuning levels to expedite the process, as well as utilize PyTorch features, specialized libraries, and efficient data pipelines to optimize training on CPUs and accelerators. You’ll also reduce model complexity, adopt mixed precision, and harness the power of multicore systems and multi-GPU environments for distributed training. By the end, you'll be equipped with techniques and strategies to speed up training and focus on building stunning models.What you will learn Compile the model to train it faster Use specialized libraries to optimize the training on the CPU Build a data pipeline to boost GPU execution Simplify the model through pruning and compression techniques Adopt automatic mixed precision without penalizing the model's accuracy Distribute the training step across multiple machines and devices Who this book is for This book is for intermediate-level data scientists who want to learn how to leverage PyTorch to speed up the training process of their machine learning models by employing a set of optimization strategies and techniques. To make the most of this book, familiarity with basic concepts of machine learning, PyTorch, and Python is essential. However, there is no obligation to have a prior understanding of distributed computing, accelerators, or multicore processors.