Download or read book Advances in Drug Research written by Bernard Testa and published by Elsevier. This book was released on 2013-10-22 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume comprises five authoritative reviews on timely topics in drug research. The first two chapters deal with chemotherapeutic agents (selective antiviral agents and cepham antibiotics) and subsequent chapters deal with the cardiovascular system and topics in neuropharmacology.
Download or read book Mandell Douglas and Bennett s Principles and Practice of Infectious Diseases E Book written by John E. Bennett and published by Elsevier Health Sciences. This book was released on 2014-09-02 with total page 5094 pages. Available in PDF, EPUB and Kindle. Book excerpt: After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to any questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you’ll find in any other ID resource. Apply the latest knowledge with updated diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on Influenza (new pandemic strains); New Middle East Respiratory Syndrome (MERS) Virus; Probiotics; Antibiotics for resistant bacteria; Antifungal drugs; New Antivirals for hepatitis B and C; Clostridium difficile treatment; Sepsis; Advances in HIV prevention and treatment; Viral gastroenteritis; Lyme Disease; Helicobacter pylori; Malaria; Infections in immunocompromised hosts; Immunization (new vaccines and new recommendations); and Microbiome. Benefit from fresh perspectives and expanded global insights from an expanded team of American and International contributors. Martin Blaser, MD, a leading expert and Muriel G. and George W. Singer Professional of Translational Medicine at New York University School of Medicine, joins veteran PPID editors John E. Bennett, MD, and Raphael Dolin, MD to continue a legacy of excellence. Find and grasp the information you need easily and rapidly with newly added chapter summaries.
Download or read book First International Moxifloxacin Symposium written by L. Mandell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: 5t The 1 International Moxifloxacin symposium took place in Berlin Germany February 18 - 20,1999. The purpose of this meeting was to introduce the medical and scientific communities to this exciting new fluoroquinolone and to define its role in the management of respiratory tract infections. The fluoroquinolones as a class are an important part of our therapeutic armamentarium and moxi floxacin is a unique addition to this class of compounds. This symposium brought together physician/scientists from around the world to present and discuss the moxifloxacin data. The information from this important meeting are presented in these proceedings and are organized under the following headings: Part I Antimicrobial chemotherapy Part II Pre-clinical microbiology Part III Pharmacology Part IV Clinical needs in the millennium Part V Round table discussion The modifications to the basic quinolone structure resulting in moxifloxacin have produced a drug with unique in vitro, and pharmacokinetic/pharmaco dynamic properties. The drug has a very broad spectrum of antimicrobial activity, is well absorbed and can be taken only once daily. Its profile makes it an excellent therapeutic option for many types of respiratory tract infections. It is hoped that our clinical and laboratory colleagues will be as excited by this data as we are and we look forward to further work with this unique and interesting compound.
Download or read book Antibiotic Optimization written by Robert C. Owens and published by CRC Press. This book was released on 2004-11-04 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on topics ranging from the economics of drug-resistant infections and the management of antimicrobial use to new information on methods to optimize the selection, route of administration, dosing, and duration of antimicrobial therapies for common infections. In addition to offering ideas on studied programmatic approaches for judi
Download or read book Emerging Infectious Diseases written by and published by . This book was released on 2011 with total page 1206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Management of Antimicrobials in Infectious Diseases written by Arch G. Mainous III and published by Springer Science & Business Media. This book was released on 2010-02-04 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent evidence suggests an increasing rate of antimicrobial resistant pathogens throughout the world. Pathogens like Staphylococcus aureus are showing substantial prevalence of resistance to antibiotics. Thus, we think that given these developments, clinicians would welcome an updated version of this book. A resource indicating appropriate, evidence-based antimicrobial treatment of infectious diseases encountered in both the hospital and outpatient settings would be of significant value to practicing clinicians. The book would focus on the clinical importance of appropriate diagnosis and treatment of infectious diseases particularly in terms of antibiotic-resistance. The resource would be valuable to countless numbers of junior-level practitioners (residents, nurse practitioners, physician-assistants). Moreover, the book could be a resource for generalists as well as infectious disease specialists.
Download or read book Supportive Care in Cancer Patients II written by Hans-Jörg Senn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second international symposium on "Supportive Care in Cancer Patients" took place March 1-3, 1990-again in St. Gallen in eastern Switzerland. It was an honor once more to welcome dozens of internationally recognized experts in the field and more than 800 participants from over 30 countries around the world: Australia, Canada, China, USSR, USA and many countries in Europe. The international nature of the grade facilitated lively and exciting contributions and critical discussions, aimed at fostering professional knowledge and skills and rethinking our personal attitudes toward cancer patients in all stages of their disease. Cancer patients need various types of tailored support, whether during active initial (curative) therapies, in phases of worrying relapsing disease, or during the demanding terminal stage of their illness. The symposium tried to bridge the strange "gap" between "curative" and "palliative" cancer care: it must be our aim to be and remain "supportive" for our patients during both curative and palliative treatment strategies! This requires extended knowledge and even more and flexible professional skills. The symposium was designed to promote improved approaches that are helpful and supportive for all our oncology patients, not just for a selected disease-or stage dependent minority.
Download or read book Antibiotics in Laboratory Medicine written by Daniel Amsterdam and published by Lippincott Williams & Wilkins. This book was released on 2014-08-08 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics in Laboratory Medicine has been a mainstay resource for practitioners/providers, investigators, and pharmaceutical researchers of new anti-infective compounds for the past 30 years. This edition includes new chapters on the predictive value of in vitro laboratory testing and the improvement of patient care in the hospital environment through antimicrobial stewardship.
Download or read book Critical Care Infectious Diseases Textbook written by Jordi Rello and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1096 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infections and their complications are a very Additionally, they have a responsibility to ensure important clinical area in the intensive care that nosocomial infections are prevented and unit setting. Community-acquired infections that antimicrobial resistance is minimized by and nosocomial infections both contribute to prudently employing antibiotic agents. It is our the high level of disease acquity common hope that this textbook will provide clinicians among critically ill patients. The importance practicing in the intensive care unit a reference of accurately diagnosing nosocomial infections to help guide their care of infected patients. To and providing appropriate therapies, to include that end we have brought together a group of antimicrobial therapy effective against the international authors to address important topics identified agents of infection, have been shown related to infectious diseases for the critical care to be important determinants of patient practitioner. outcome. Critical care practitioners are in a Jordi Rello, M. D. , Ph. D. unique position in dealing with infectious Jordi Valles, M. D. , Ph. D. diseases. They are often the initial providers of Marin H. Kolle!, M. D. care to seriously ill patients with infections. SECTION 1: GENERAL ASPECTS ]. Rello 1.
Download or read book Macrolide Antibiotics written by W. Schönfeld and published by Springer Science & Business Media. This book was released on 2002-03-01 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are only very few chemical classes of antibiotics in medical use, and these have originated over a span of more than 60 years of research. Almost half a century ago, the first member of the macrolides, erythromycin, was introduced as a treatment option for bacterial infections. Erythromycin is a very complex fermentation product obtained from the soil bacterium Saccharopolyspora ery thraea (originally named Streptomyces erythreus). The success of erythromycin, based on its efficacy and tolerability, stimulated researchers throughout the world to undertake intense efforts to understand the biology and chemistry of macrolides and to use this experience to improve the properties of this compound class. The second generation of macrolides, based on chemical modifications of erythromy cin, is currently being in broad use, especially for treatment of respiratory tract infections. We presently foresee the introduction of a new generation of macro lides, i. e. the ketolides, which have the potential to overcome rising resistance problems. This monograph is intended to give the interested reader an overview on "macrolide experience", covering important areas from basic research to clinical use. Starting from a historic overview, the essential basic parameters - efficacy, pharmacokinetics, pharmacodynamics, and pharmacology - are highlighted in order to introduce the reader to the rationale for clinical use of macrolides. The following group of chapters cover the complex chemistry of the macro lactone structures, giving historic background, basic structure-activity relation ships of various derivatization strategies, and perspectives for future discovery of new semisynthetic macrolide antibiotics.
Download or read book Handbook of Animal Models of Infection written by Merle A. Sande and published by Academic Press. This book was released on 1999-05-28 with total page 1169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Animal Models of Infection is a complete revision of a three-volume text that was published in 1986. It incorporates the major advances in the field during the past decade, in particular those concerning molecular biological procedures and new models that have been developed. It focuses on both methods and techniques, which makes it an essential and comprehensive reference as well as a benchtop manual. The Handbook will help investigators save time and effort in formulating an approach to test a new potential therapeutic agent or combination of agents for in vivo efficacy and to position the therapy for specific infections where it may have therapeutic promise. The book is divided into five sections; the first covering the general methodologies, followed by sections describing experimental bacterial, mycotic, parasitic, and viral infections. - Discusses ethical and safety aspects in an introductory background section - Covers principles of animal care and current techniques appropriate for the use of animal models of infection - Details a wide range of animals including rodents, rabbits, cats, and primates - Provides hands-on descriptions of how to set up the model - Discusses the major advantages and limitations of each model - Ensures full coverage of bacterial, fungal, viral, and parasitic infections
Download or read book Bennett Brachman s Hospital Infections written by William R. Jarvis and published by Lippincott Williams & Wilkins. This book was released on 2013-10-17 with total page 1339 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over three decades, Bennett & Brachman’s Hospital Infections has been a respected and influential resource in the prevention and control of healthcare-associated infections (HAIs). Now in its Sixth Edition, the book continues to provide readers with the latest information in the field of healthcare epidemiology, infection control, patient safety, and the prevention and control of HAIs. Many of the current contributors are or were employed by or trained at the Centers for Disease Control and Prevention (CDC) and have a thorough knowledge of healthcare epidemiology. Topics covered include HAI epidemiology; surveillance; control programs; antimicrobial stewardship;antimicrobial resistance; mechanisms of resistance; sterilization and disinfection; food-borne diseases; the role of the laboratory, intensive care unit, operating room, dialysis, and nursery settings; and specific hospital-acquired infections.
Download or read book Neonatal and Pediatric Pharmacology written by Sumner J. Yaffe and published by Lippincott Williams & Wilkins. This book was released on 2011 with total page 1072 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Neonatal and Pediatric Pharmacology offers guidelines for safe, effective, and rational drug therapy in newborns, children and adolescents. The book provides relevant and useful data on the molecular, physiologic, biochemical, and pharmacologic mechanisms of drug action and therapy in this population. The authors identify areas of innovative basic and translational research necessary for the continuing evaluation and development of drugs for the fetus, newborns, children and adolescents. Neonatal and Pediatric Pharmacology is is a valuable reference for all health care professionals who treat the fetus, newborns, children, and adolescents, including neonatologists, nurses, pediatricians, general practitioners, students, obstetricians, perinatologists, surgeons and allied health professionals. It will be useful anytime during the day and especially in the middle of the night when knowledge of appropriate indications, safe and effective use, dosage, and therapeutic regimen for a certain drug or molecular entity is immediately needed. The book is also directed to those involved in basic, clinical, and other academic pharmacological research, the pharmaceutical industry, and regulatory agencies dealing with drug and therapeutic developments for this population. Those teaching pharmacology and therapeutics will find this compilation of information extremely useful in preparing teaching materials"--Provided by publisher.
Download or read book Clinical Approach to Infection in the Compromised Host written by Robert H. Rubin and published by Springer. This book was released on 2013-11-11 with total page 777 pages. Available in PDF, EPUB and Kindle. Book excerpt: `With admirable clarity the authors-all highly regarded experts in their respective fields-present the clinician with a supremely readable and practical text. The emphasis here is pragmatic, although there is sufficient pathogenesis and physiology to provide a fine balance.'-Journal of the American Medical Association, from a review of the second edition. This updated and profusely illustrated edition is 75% larger than its first incarnation. New coverage includes transplantation medicine, AIDS, patient management, and host-parasite interactions.
Download or read book Antibiotic Policies written by Ian M. Gould and published by Springer Science & Business Media. This book was released on 2006-01-26 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: For 50 years, antibiotics have been dispensed like sweets. This must not be allowed to continue. This unique book assembles contributions from experts around the world concerned with responsible use of antibiotics and the consequences of overuse. For the first time, it provides up to the minute texts on both the theoretical aspects of antibiotic stewardship and the practical aspects of its implementation, with consideration of the key differences between developed and developing countries. All concerned with teaching, practice and administration of clinical medicine, surgery, pharmacy, public health, clinical pharmacology, microbiology, infectious diseases and clinical therapeutics will find Antibiotic Policies: Theory and Practice essential reading. Antibiotic use and resistance is not just the responsibility of specialists in the field but the responsibility of all doctors, pharmacists, nurses, healthcare administrators, patients and the general public.
Download or read book Clinical Use of Antiviral Drugs written by Erik de Clercq and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antiviral chemotherapy has come of age, and, after an initial slow pro gress, the development of new antiviral agents has proceeded at a more rapid pace and the perspectives for their clinical use have increased considerably. Now, 25 years after the first antiviral assay (idoxuridine) was introduced in the clinic, it is fitting to commemorate the beginning of the antivirals' era. In its introductory chapter B.E. Juel-Jensen touches on what may be con sidered as five of the most fundamental requirements of an antiviral drug : efficacy, relative non-toxicity, easy solubility, ready availability and rea sonable cost. Surely, the antiviral drugs that have so far been used in the clinic could still be improved upon as one or more of these five essential demands are concerned. How is all began is narrated by W.H. Prusoff. The first antiviral drugs to be used in humans were methisazone and idoxuridine, the former, which is now of archival interest, in the prevention of smallpox, the latter, which was approved for clinical use in the United States in 1962, for the topical treatment of herpetic keratitis. In terms of potency, also because of solubility reasons, idoxuridine has been superseded by trifluridine in the topical treatment of herpes simplex epithelial keratitis. H.E. Kaufman did not find trifluridine or acyclovir ef fective in the treatment of deep stromal keratitis or iritis and he reckons that other antiviral drugs (i.e. bromovinyldeoxyuridine) would not be effec tive either.
Download or read book PROGRESS IN DRUG RESEARCH 31 written by JUCKER and published by Springer Science & Business Media. This book was released on 1981 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:
