Download or read book Intermolecular Cross talk in Tumor Metastasis written by George G. Skouteris and published by IOS Press. This book was released on 1999 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metastasis of tumours is a sequence of events taking place after the appearance of a primary tumour. The potency of a tumour to metastasise greatly depends on the molecular interactions between tumour components (cellular differentiation and heterogeneity, surface antigenic determinants etc.) and the micro-environment. The complexity and diversity in the composition of tissue micro-environment is in great extent determining the metastatic behaviour or a primary tumour. Extracellular matrix composition, rearrangement of cytoskeleton, cell antigenicity , expression of metastasis-related novel genes, cell adhesion and novel therapeutical approaches such as blockage of angiogenesis, are the major topics discussed in detail in this volume.
Download or read book Environmental Health Perspectives written by and published by . This book was released on 2000 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Impact of Tumor Extracellular Matrix Cross Talk on Cancer Hallmarks written by Hamid Morjani and published by Frontiers Media SA. This book was released on 2021-04-05 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Cancer Handbook written by Malcolm Alison and published by . This book was released on 2002 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Cancer Handbook 2 Volume Set written by Malcolm Alison and published by John Wiley & Sons. This book was released on 2007-07-30 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cancer Handbook provides a comprehensive overview of scientific and clinical information in cancer research and medicine (oncology). This area is one of the most intensively studied in biology and medicine, resulting in a huge amount of new information being published every year. This book summarizes and explains key facts and recent developments. It is aimed at a wide variety of readers who need easy access to knowledge concerning all major aspects of cancer biology, without too much clinical detail or specialist research material. The Cancer Handbook stands out from existing oncology textbooks and reference works in that it bridges the gap between the molecular biology of cancer and clinical diagnosis and treatment. As more and more laboratory research is applied to clinical management, e.g. the use of monoclonal antibodies as drugs, it is important that clinicians understand the aetiology of the disease and the molecular basis of the new therapeutic approaches. It is also important for laboratory scientists to appreciate the potential applications of their research and the practical issues involved in translating it to clinical practice. For this second edition, all the sections have been fully revised and updated, with new chapters addressing important topics that have gained prominence in recent years. New editors and authors have brought additional expertise to the project. For example, in the section on the Molecular and Cellular Basis of Cancer, there are new chapters on stem cells, epigenetics, and microRNAs, as well as chapters on the links between cancer and development and inflammation. In the Treatment section, the emphasis is now on multidisciplinary team management of different cancers, plus there are new chapters on clinical trial design, RNA interference and rational drug design. The page design and the quality of the diagrams has been improved, with all illustrations now in full colour. The glossary has been made more informative and easy to use.
Download or read book Tumor Angiogenesis Regulators written by Ruben R. Gonzalez-Perez and published by CRC Press. This book was released on 2013-05-09 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emphasis of this book is on mechanisms and pathways regulating the expression and actions of classical and novel tumor angiogenesis regulators. The contributors discuss their underlying biology as well as anti-angiogenic drugs currently in use to fight different cancers. The book provides an insight on how factors such as obesity, diabetes, and other metabolic disorders can influence the development and growth of cancer. It is of significant interest not only to oncologists but also to a wide range of medical practitioners and researchers.
Download or read book Nasopharyngeal Cancer written by Jiade J. Lu and published by Springer Science & Business Media. This book was released on 2010-01-13 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nasopharyngeal Cancer - Multidisciplinary Management provides a comprehensive account of the current state of knowledge on nasopharyngeal cancer and its multidisciplinary management. The first ten chapters document contain essential background information on subjects such as epidemiology, pathogenesis, molecular biology, pathology, and the use of imaging in diagnosis and staging. Subsequently, the various treatment options and combinations in a range of settings are examined in depth. Detailed attention is given to the roles of concurrent, adjuvant, and neoadjuvant chemotherapy and advanced radiotherapy techniques. Further chapters then explore surgical treatment, follow-up, treatment of metastatic disease, treatment-related complications, and nasopharyngeal cancer in children. This is an important book that will prove essential reading for the radiation oncology community worldwide and meet the need for substantial improvements in knowledge of modern techniques.
Download or read book The Cell Cycle in the Central Nervous System written by Damir Janigro and published by Springer Science & Business Media. This book was released on 2008-01-23 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Cycle in the Central Nervous System overviews the changes in cell cycle as they relate to prenatal and post natal brain development, progression to neurological disease or tumor formation.Topics covered range from the cell cycle during the prenatal development of the mammalian central nervous system to future directions in postnatal neurogenesis through gene transfer, electrical stimulation, and stem cell introduction. Additional chapters examine the postnatal development of neurons and glia, the regulation of cell cycle in glia, and how that regulation may fail in pretumor conditions or following a nonneoplastic CNS response to injury. Highlights include treatments of the effects of deep brain stimulation on brain development and repair; the connection between the electrophysiological properties of neuroglia, cell cycle, and tumor progression; and the varied immunological responses and their regulation by cell cycle.
Download or read book Pathobiology of Human Disease written by and published by Elsevier. This book was released on 2014-08-01 with total page 4376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human Organ Systems Molecular Pathology/Basic Mechanisms of Diseases Animal Models/Other Model Systems Experimental Pathology Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2005 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The British National Bibliography written by Arthur James Wells and published by . This book was released on 2001 with total page 1600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Cancer Research written by George F. Vande Woude and published by Academic Press. This book was released on 2009-09-12 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including tumor dormancy, micro RNA, tumor angiogenesis, cancer in mouse models, liposome based chemo and autoimmunotherapy, signaling in angiogenesis, targeted cancer therapy, and regulatory t-cells.
Download or read book Cancer Forum written by and published by . This book was released on 2000 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tumor Angiogenesis written by Sophia Ran and published by BoD – Books on Demand. This book was released on 2012-02-17 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor angiogenesis is the main process responsible for the formation of new blood vessels that promote tumor growth and metastasis. This process is driven by potent pro-angiogenic factors that are predominant in the tumor environment and are produced by both malignant cells and the host cells recruited to the tumor site. Tumor environment is characterized by the imbalance between pro-angiogenic and anti-angiogenic factors, which drives the construction of numerous but structurally defective vessels. These poorly perfused and abnormal vessels significantly contribute to the tumor pathology not only by supporting the expansion of the tumor mass but also by promoting chronic inflammation, enhancing thrombosis, impeding drug delivery, and disseminating tumor cells. These problems associated with tumor vasculature continue to attract great attention of scientists and clinicians interested in advancing the understanding of tumor biology and development of new drugs. This book complies a series of reviews that cover a broad spectrum of current topics related to the pathology of tumor blood vessels including mechanisms inducing new vessels, identification of new targets for inhibition of tumor angiogenesis, and potential clinical use of known and novel anti-angiogenic therapies. The book provides an update on tumor angiogenesis that could be useful for oncologists, cancer researchers and biologists with interests in vascular and endothelial cell behavior in the context of cancer.
Download or read book Interaction of Immune and Cancer Cells written by Magdalena Klink and published by Springer Science & Business Media. This book was released on 2013-11-26 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tumor environment is a dynamic network that includes cancer cells, immune cells, fibroblasts, endothelial cells, extracellular matrix, cytokines and receptors. The aim of this book is to summarize the role of these components, especially immune cells, in tumor suppression and/or progression and describe in detail why tumor cells can survive and spread in spite of the antitumor response of immune cells. Since immunotherapy is an attractive approach to cancer therapy, this book also provides information on the two main strategies: monoclonal antibodies and adaptive T cell immunotherapy, with a focus on recent human clinical trials. The book provides a state-of-the-art, comprehensive overview of immune cells in cancer and is an indispensable resource for scientists and medical doctors working and/or lecturing in the field of cancer research and immunology.
Download or read book Tumor Ecosystem written by Erwei Song and published by Springer Nature. This book was released on 2023-07-20 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book intends to report new concept of onco-spheres in cancer ecosystem. Onco-spheres are defined as where cancer cells (living organisms) dynamically interact with nontumor cellular (other living organisms) and noncellular components (non-living environmental factors) in the ‘host’ internal environment (habitat) to construct a self-sustainable cancer ecosystem, which can be scoped at three different levels: primary/regional, distal and systemic onco-spheres. Cancer cells should be conceived as ‘living organisms’, interacting with cellular or noncellular components in the host internal environment, not only with the local tumor microenvironment (TME) but also constantly communicating with a distant organ niche as well interacting with the host’s nervous, endocrine and immune systems, to construct a self-sustainable ‘biosphere’, as we termed the tumor ecosystem. By looking at the interaction of cancer and host as a unique ecosystem, we will use ecology principles to further delineate the features of the dynamics of the tumor ecosystem. As the pioneer in proposing this concept, we feel that this full-scale overview of the tumor ecosystem is able to inform the readers about this concept, and to pave the way for designing novel therapeutic strategies on actionable targets within tumor ecosystem. The book is likely to be of interest to immunologist, biologist, medical students, researchers and general public who wish to learn more on this new concept of tumor ecosystem, and how this could be applied in many fields of research.
Download or read book Angiogenesis written by William D. Figg and published by Springer Science & Business Media. This book was released on 2008-05-24 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Judah Folkman is considered the "father of angiogenesis." Because of Folkman's discovery and research, the possibilities of angiogenic therapy have broadened beyond cancer to many noncancerous diseases. Angiogenesis: An Integrative Approach from Science to Medicine is a comprehensive, concise summary of tumor angiogenesis. It is an up-to-date and authoritative reference for the angiogenesis field as it relates to oncology. This book represents the first collection in a volume of which Folkman is co-editor. Folkman has authored nearly 400 original papers and more than 100 book chapters.
