Download or read book Interactive Phenomena in the Cardiac System written by S. Sideman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cardiac system represents one of the most exciting challenges to human ingenuity. Critical to our survival, it consists of a tantalizing array of interacting phenomena, from ionic transport, membrane channels and receptors through cellular metabolism, energy production to fiber mechanics, microcirculation, electrical activation to the global, clinically observed, function, which is measured by pressure, volume, coronary flow, heart rate, shape changes and responds to imposed loads and pharmaceutical challenges. It is a complex interdisciplinary system requiring the joint efforts of the life sciences, the exact sciences, engineering and technology to understand and control the pathologies involved. The Henry Goldberg Workshops were set up to address these multivariable, multidisciplinary challenges. Briefly, our goals are: To encourage international cooperation and foster interdisciplinary interaction between scientists from the different areas of cardiology; to relate microscale cellular phenomena to the global, clinically manifested cardiac function; to relate conceptual modeling and quantitative analysis to experimental and clinical data; to gain an integrated view of the various interacting parameters, identify missing links, catalyze new questions, and lead to better understanding of the cardiac system. The outstanding success of past workshops has encouraged their continuation. The first Henry Goldberg Workshop, held in Haifa in 1984, introduced the concept of interaction between mechanics, electrical activation, perfusion and metabolism, emphasizing imaging in the clinical environment. The second Workshop, in 1985, discussed the same parameters with a slant towards the control aspects.
Download or read book Oxygen Transport to Tissue XV written by International Society on Oxygen Transport to Tissue. Annual Meeting and published by Springer Science & Business Media. This book was released on 1994 with total page 984 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprises the proceedings from the 20th meeting of the International Symposium on Oxygen Transport to Tissue (ISOTT). This is volume 345 of a series in Advances in Experimental Medicine and Biology. The purpose is to publish the proceedings from the meeting of the ISOTT. This is an important work, providing synopses by experts in their fields of the current status of work on oxygen transport to tissue. As such, the objectives of the authors are met. The book is written for basic scientists, clinical scientists, and students with specialized interests. Each article is written by a credible author who is working on the specific topic. The quality of the book is attributable to the publication approach using photo-ready manuscripts provided by each author. The resultant differences in fonts, point size, spacing, justification, and graphics styles gives the book a lack of graphic continuity, although this is probably not important to the audience. The references are current and pertinent. The table of contents and index are adequate. The book quality is adequate. It is a logical and appropriate volume in this series. This book will serve best as a reference source for researchers. It would be a good addition to libraries. The book would probably only be of limited use for individual purchase.
Download or read book Regulation of Tissue Oxygenation Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Analysis and Assessment of Cardiovascular Function written by Gary M. Drzewiecki and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to provide the researcher and clinician with the recent developments in the analysis and assessment of cardiovascular func tion. The chapters are organized into sections that correspond with the various anatomical levels of the cardiovascular system. To a large extent, recent focus on the cardiovascular system function has been directed at the molecular level to the near exclusion of the tissue and organ function. While this may be useful in developing new therapeutic drugs, it does not aid the cardiologist or surgeon, who routinely deal with patient symptoms. This book integrates the micro-level and organ-level function so that new infor mation may be assimilated into the cardiovascular system as a whole. Within each section, the chapters have been arranged to progress from recent theoretical developments, to experimental research, and finally to clinical applications. This approach facilitates the timely transfer of infor mation from basic research to the clinic. The strength of the analytical approach will be evident to the reader. The theoretical analysis offers guidance to experimental design and, in some cases, offers solutions where measurements are as yet unattainable. In moving from newly attained knowledge to clinical practice, this book emphasizes the noninvasive meth in the future as technological advances ods. Such methods are desirable occur and the trend towards early preventive diagnosis is sought. What follows are highlights of new developments covered in each section of the book.
Download or read book Sex Specific Analysis of Cardiovascular Function written by Peter L. M. Kerkhof and published by Springer. This book was released on 2018-07-26 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data. This innovative title is the first to offer the elements necessary to consider sex-related properties in both clinical and basic studies regarding the heart and circulation on multiscale levels (i.e. molecular, cellular, electrophysiologically, neuroendocrine, immunoregulatory, organ, allometric, and modeling). Observed differences at (ultra)cellular and organ level are quantified, with focus on clinical relevance and implications for diagnosis and patient management. Since the cardiovascular system is of vital importance for all tissues, Sex-Specific Analysis of Cardiovascular Function is an essential source of information for clinicians, biologists, and biomedical investigators. The wide spectrum of differences described in this book will also act as an eye-opener and serve as a handbook for students, teachers, scientists and practitioners.
Download or read book Heart s Vortex written by Ares Pasipoularides and published by PMPH-USA. This book was released on 2009-11 with total page 958 pages. Available in PDF, EPUB and Kindle. Book excerpt: This outstanding resource provides a comprehensive guide to intracardiac blood flow phenomena and cardiac hemodynamics, including the developmental history, theoretical frameworks, computational fluid dynamics, and practical applications for clinical cardiology, cardiac imaging and embryology. It is not a mere compilation of the most up-to-date scientific data and relevant concepts. Rather, it is an integrated educational means to developing pluridisciplinary background, knowledge, and understanding. Such understanding allows an appreciation of the crucial, albeit heretofore generally unappreciated, importance of intracardiac blood flow phenomena in a host of multifaceted functional and morphogenetic cardiac adaptations. The book includes over 400 figures, which were prepared by the author and form a vital part of the pedagogy. It is organized in three parts. Part I, Fundamentals of Intracardiac Flows and Their Measurement, provides comprehensive background from many disciplines that are necessary for a deep and broad understanding and appreciation of intracardiac blood flow phenomena. Such indispensable background spans several chapters and covers necessary mathematics, a brief history of the evolution of ideas and methodological approaches that are relevant to cardiac fluid dynamics and imaging, a qualitative introduction to fluid dynamic stability theory, chapters on physics and fluid dynamics of unsteady blood flows and an intuitive introduction to various kinds of relevant vortical fluid motions. Part II, Visualization of Intracardiac Blood Flows: Methodologies, Frameworks and Insights, is devoted to pluridisciplinary approaches to the visualization of intracardiac blood flows. It encompasses chapters on 3-D real-time and "live 3-D" echocardiography and Doppler echocardiography, CT tomographic scanning modalities, including multidetector spiral/helical dataset acquisitions, MRI and cardiac MRA, including phase contrast velocity mapping (PCVM), etc. An entire chapter is devoted to the understanding of post processing exploration techniques and the display of tomographic data, including "slice-and-dice" 3-D techniques and cine-MRI. Part II also encompasses an intuitive introduction to CFD as it pertains to intracardiac blood flow simulations, followed--in separate chapters--by conceptually rich treatments of the computational fluid dynamics of ejection and of diastolic filling. An entire chapter is devoted to fluid dynamic epigenetic factors in cardiogenesis and pre- and postnatal cardiac remodeling, and another to clinical and basic science perspectives, and their implications for emerging research frontiers. Part III contains an Appendix presenting technical aspects of the method of predetermined boundary motion, "PBM," developed at Duke University by the author and his collaborators.
Download or read book The Arterial Circulation written by John K-J Li and published by Springer Science & Business Media. This book was released on 2000-05-05 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: After yet another decade of leaming, experimenting, and inves tigating since my first book, Arterial System Dynamics, the many new medical breakthroughs and technological advances have inspired me to write this book to bridge the gap between basic research and clinical applications. The application of physical principles and quantitative approaches to the understanding of the arterial circulation and its interactions with the heart in normal and diseased conditions form the basis of The Arterial Circulation. Knowledge of the physiology and rheology of arteries, as well as all of their structural-functional corre lates, is a necessary prerequisite to the proper hemodynamic interpretatiqn of pressure-flow relations and the pulsatile transmis sion characteristics in different arteries. The natural coupling and interactions of the heart, the coronary circulation, and the arterial system necessitate analysis of alterations to global functioning. Modeling provides a tool for isolating and predicting parameter changes and is employed throughout the book. Experimental data are provided for model validations, and also for more realistic interpretations. Techniques and new methods for clinical hemo dynamic measurement and diagnosis are included to help the reader un derstand the physical principles underlying such abnormal cardiovascular functions as hypertension, stenosis, and myocardial ischemia. The progressive changes in vascular properties during aging are also discussed. Modem approaches utilizing computer mode ling and allomery are presented with selected examples, such as combined hypertension and aortic valve stenosis, and ventricular hypertrophy.
Download or read book International Conference on Advancements of Medicine and Health Care through Technology 23 26 September 2009 Cluj Napoca Romania written by Simona Vlad and published by Springer Science & Business Media. This book was released on 2010-02-01 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Projections for advances in medical and biological technology will transform medical care and treatment. This in great part is due to the result of the interaction and collaboration between medical sciences and engineering. These advances will result in substantial progress in health care and in the quality of life of the population. Frequently however, the implications of technologies in terms of increasing recurrent costs, additional required support services, change in medical practice and training needs are underestimated. As a result, the widespread irrational use of te- nologies leads to a wastage of scarce resources and weakens health systems performance. To avoid such problems, a syst- atic and effective Health Technology System must be developed and introduced, requiring the support and commitment of decision makers of all levels of the health system. The MediTech2009 conference aims to provide a special opportunity for the Romanian professionals involved in basic - search, R&D, industry and medical applications to exchange their know-how and build up collaboration in one of the most human field of science and techniques. The conference is intended to be an international forum for researchers and practit- ners interested in the advance in, and applications of biomedical engineering to exchange the latest research results and ideas in the areas covered by the topics (and not only!). We believe the reader will find the proceedings an impressive document of progress to date in this rapidly changing field.
Download or read book New and Renewable Technologies for Sustainable Development written by Naim Hamdia Afgan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sustainable development encompasses economic, social, and ecological perspectives of conservation and change in natural resources. It is generally defined as development that meets the needs of the present without compromising the ability of future generations to meet their own needs. This definition is based on the ethical imperative of equity within and between generations. Moreover, apart from meeting; "the basic needs of all"; sustainable development implies sustaining the natural life support systems on Earth, and extending to all the opportunity to satisfy their aspirations for a better life. Hence, sustainable development is more precisely defined as a process of change in which the exploitation of resources, the direction of investments, the orientation of technological development, and institutional change are all in harmony and enhance both current and future potential to meet human needs and aspiration. To date, various definitions and stationary-state criteria of sustainability have been proposed. Many authors have been concerned with only part of the problem, such as the technological assumptions, the ability to substitute natural resources in economic transformation processes, and the resilience and importance of ecological processes. But, the social dimension did not receive the same attention, and has not been adequately integrated into formal analysis. The engineering community has to play an important role in sustainable development with appropriate evaluation of the engineering systems. In this respect energy, water and environment systems require multi-criteria evaluation methods for the assessment of the economic, environmental and social aspect of the systems.
Download or read book Molecular and Subcellular Cardiology written by S. Sideman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Henry Goldberg Workshops were set up to address the following goals: (1) To foster interdisciplinary interaction between scientists and cardiologists, identify missing links, and catalyze new ideas. (2) To relate basic microscale phenomena to the global, clinically manifested cardiac function. (3) To relate conceptual modeling and quantitative analysis to experimental and clinical data. (4) To encourage international cooperation so as to disperse medical and technological knowhow and lead to better understanding of the cardiac system. The first Henry Goldberg Workshop, held in Haifa in 1984, introduced the concept of interaction between cardiac mechanics, electrical activation, perfusion, and metabolism, emphasizing imaging in the clinical environment. The second Workshop, in 1985, discussed the same parameters with a slant towards the control aspects. The third Goldberg Workshop, held in the USA at Rutgers University in 1986, highlighted the transformation of the microscale activation phenomena to macroscale activity and performance, relating electrophysiology, energy metabolism, and cardiac mechanics. The fourth Goldberg Workshop, in 1987, continued the effort to elucidate the interactions among the various parameters affecting cardiac performance, with emphasis on the ischemic heart. The fifth Workshop, held in Cambridge, UK, in 1988, dwelt on the effects of inhomogeneity of the cardiac muscle on its performance in health and disease. The sixth Workshop highlighted the role of new modem imaging techniques, that allow us to gain more insight into local and global cardiac performance in cardiac research and clinical practice.
Download or read book Systolic and Diastolic Function of the Heart written by Neil B. Ingels and published by IOS Press. This book was released on 1996 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapter 22: Crossbridge and Muscle Properties, Energetics, and Pressure-Volume Area -- Chapter 23: Constancy and Variability of Oxygen Costs of Mechanical Energy (PVA) and Contractility (Emax) -- Chapter 24: Tight Coupling between Regional Myocardial Oxygen Consumption and Contractile Function -- Chapter 25: Force-Frequency Relation, Force-Interval Relation, and Mechanical Restitution -- Chapter 26: Elastance-Based Mechanical Restitution Provides Data from the Intact Heart Not Available from Any Other Technique -- Chapter 27: Contractility Indices -- Chapter 28: Searching for Indices of Contractility Is Counterproductive -- Chapter 29: Rapid Contractile Upregulation Rematches Stroke Work to Increased Afterload Independent of Ventricular Geometry, Afterload-Related Coronary Perfusion Pressure Fluctuations and Baseline Contractile State -- Chapter 30: Wall Thickening, Shears, and Cleavage Planes -- Chapter 31: Mechanisms of Large Ventricular Wall Shortening and Thickening -- Chapter 32: Twisting, Torsion, and Other Shears -- Chapter 33: Ventricular Twist and Its Relationship to Pressure Volume and Shortening -- Chapter 34: Differences in Systolic and Diastolic Torsional Deformation of the Left Ventricle -- Chapter 35: Coronary Flow, Systolic Perfusion, and the "Gregg Phenomenon -- Chapter 36: Intramyocardial Hydraulic Regulation of Cardiac Mechanics and Energetics -- Chapter 37: Left Ventricular Afterload and Arterial Coupling -- Indexes -- Author Index -- Affiliation Index -- Subject Index
Download or read book Cardiac Adaptation and Failure written by Masatsugu Hori and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in cellular physiology and molecular biology have now disclosed the metabolic changes and adaptational responses of the heart to various kinds of stresses. Topics covered in this volume include the regulation of myocardial proteins in mechanical overload, the alteration of adrenoceptors in the stressed heart, metabolic adaptation in cardiac hypertrophy, intracellular calcium metabolism in the ischemia-reperfused myocardium, calcium overload as a cause of myocardial stunning, acquisition of ischemic tolerance by ischemic preconditioning, factors that accelerate myocardial injury, and ventricular remodeling in the ischemic heart. As an update of the latest findings in basic cardiology, this book will benefit both researchers and clinical practitioners.
Download or read book Coronary Circulation written by Ghassan S. Kassab and published by Springer. This book was released on 2019-05-15 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive text examines both global and local coronary blood flow based on morphometry and mechanical properties of the coronary vasculature. Using a biomechanical approach, this book addresses coronary circulation in a quantitative manner based on models rooted in experimental data that account for the various physical determinants of coronary blood flow including myocardial-vessel interactions and various mechanisms of autoregulation. This is the first text dedicated to a distributive analysis (as opposed to lumped) and provides digital files for detailed anatomical data (e.g., diameters, lengths, node-to-node connections) of the coronary vessels. This book also provides appendices with specific mathematical formulations for the biomechanical analyses and models in the text. Written by Dr. Ghassan S. Kassab, a leader in the field of coronary biomechanics, Coronary Circulation: Anatomy, Mechanical Properties, and Biomechanics is a synthesis of seminal topics in the field and is intended for clinicians, bioengineers, and researchers as a compendium on the topic. The detailed anatomical and mechanical data provided are intended to be used as a platform to address new questions in this exciting and clinically very important research area.
Download or read book Purines and Myocardial Protection written by Anwar-Saad A. Abd-Elfattah and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical review of the most up-to-date research on purines and myocardial protection. The role of purines in reversible `myocardial stunning' and irreversible (myocardial infarction) ischemic injury, ventricular arrhythmias, and ischemic preconditioning is discussed in detail, by experts. All reviews address recent and rather controversial issues on purines and myocardial protection. Mechanisms of cardioprotection of exogenous versus endogenous purines are discussed in detail. The contribution of internationally recognized experts in the field of purines and cardiovascular physiology and in myocardial protection makes this a unique and interesting book for clinicians, basic scientists and students.
Download or read book Fluid Therapy in Animals written by William W. Muir and published by Frontiers Media SA. This book was released on 2022-03-16 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Visceral and Obstetric Osteopathy written by Caroline Stone and published by Elsevier Health Sciences. This book was released on 2006-12-28 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title covers the osteopathic approach to patient management for pregnant women (pre and post partum), and for patients presenting with a variety of visceral conditions such as asthma, chronic breathing problems, various gastro-intestinal tract disorders such as irritable bowel syndrome, other conditions such as post operative scarring and pain, and many others. It also addresses the improvement of management of general musculo-skeletal problems such as back pain, neck pain and so on, by incorporating visceral and fascial perspectives into those examinations and treatment protocols. Current clinical knowledge, and ethical and medical constraints are dissucssed throughout. Supported by clear illustrations and clinical case studies this books makes an excellent resource for all practitioners and students of osteopathy. . Author is a world renowned lecturer in visceral osteopathy for the last 15 years, and more recently in the field of obstetrics. . Potentially a core textbook for undergraduate and post graduate courses . Clear, functional presentation . Abundant illustrations and photographs . Case studies are included to supplement the text . Visceral osteopathy is the new 'cranio-sacral therapy' in osteopathy/manual therapy and this is the text to fill the gap. Foreword by Jean-Pierre Barral.
