Download or read book Interaction of Pathogenic Escherichia coli with the Host Pathogenomics Virulence and Antibiotic Resistance written by Tânia Aparecida Tardelli Gomes and published by Frontiers Media SA. This book was released on 2021-05-24 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Escherichia coli in the Americas written by Alfredo G. Torres and published by Springer. This book was released on 2016-10-14 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial diarrheal diseases remain an important leading cause of preventable death, especially among children under five in developing countries. In the American continent, diarrheal disease and other health complications caused by Escherichia coli constitute a major public health problem, and, therefore, several research groups have dedicated their effort to understand this pathogen and provide feasible solutions to prevent, treat and reduce E. coli infections. The Latin American Coalition for Escherichia coli Research (LACER) was created as a multidisciplinary network of international research groups working with E. coli with the ultimate goal of advancing understanding of E. coli, and to prepare the next generation of American E. coli investigators. As such, this book compiles the knowledge of these investigators about E. coli, a commensal bacteria living inside its host, and a pathogen causing disease in animals and humans. Escherichia coli in the Americas contains a series of 15 chapters written by experts, covering basic concepts regarding the different categories of E. coli, including their environmental niche, virulence mechanisms, host reservoir, and disease outcomes, as well as diagnosis, vaccine development and treatment. This book's target audience include trainees and students learning about the basic and clinical aspects of E. coli pathogenesis, as well as experts around the globe who wish to learn more about this pathogen and the public health impact this bacteria has in America.
Download or read book Pathogenic Escherichia Coli written by Stefano Morabito and published by Caister Academic Press Limited. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, a great deal of knowledge has accumulated on the features associated with the virulence of pathogenic E. coli. A large number of virulence genes have been identified and their products characterized. Great strides have been made in the understanding of the pathogenic mechanisms and the bacterium-host interaction. However, much remains elusive in the understanding of pathogenicity at a cellular and sub-cellular level. This is largely due to E. coli genome's plasticity: it generates great variability and facilitates the rapid emergence of new pathogenic variants. Elucidating the mechanisms underlying the evolution of these pathogens and their interactions with the host are key stages for disease prevention. This book reviews the most important recent findings of the studies on pathogenic E. coli, providing a timely overview of the field. The topics covered include: epidemiology of the disease in humans and animals and the biological mechanisms that shaped the pathogenic types of E. coli * shiga toxins * subtilase cytotoxin * cell cycle modulating toxins * the heat stable and heat labile enterotoxins * haemolysins * structural, molecular, and functional characteristics of A/E lesions * colonization factor antigens of ETEC * enteroaggregative adhesion * host cell invasion * the development of vaccinal strategies to confront the burden of disease. The chapters are written from a molecular and cellular biology standpoint, but also include discussions of the findings with a wider perspective, including considerations of public health and the impact on animal productions. The book will be essential reading for everyone working on these and related pathogens.
Download or read book Pathogenic Escherichia Coli in Latin America written by Alfredo G. Torres and published by Bentham Science Publishers. This book was released on 2010 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogenic Escherichia coli are known to be a common cause of diarrheal disease - a common cause of frequently occurring bacterial infections in children and adults in developing countries. It poses a significant problem in Latin America. Pathogenic Escherichia coli in Latin America presents current information on understanding pathogenic E. coli in Latin America and outlines prospects for future research in this region. It features a unique, comprehensive analysis of the most common categories of E. coli associated with diarrheal illness in Latin America. The aim of this book is to help epide.
Download or read book Microbiology of Urinary Tract Infections written by Payam Behzadi and published by BoD – Books on Demand. This book was released on 2019-02-13 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Generally, in accordance with anatomical characteristics, urinary tract infections (UTIs) and in particular recurrent UTIs occur in women; in contrast, UTIs normally occur in men with different predisposing factors. There are several types of UTIs, including asymptomatic and symptomatic, complicated and uncomplicated, acute and chronic with a diversity of microbial pathogens. In pathogens, virulence factors and genes determine the type and severity of the UTIs. Obviously, UTIs are a huge problem in global public healthcare systems with a wide range of predisposing factors, including gender, microbial agent, the host's immune deficiencies, genetic diseases, catheterization, etc. The recent items determine the microbiology of UTIs. Accurate diagnosis and definitive treatment are the key to UTI reduction.
Download or read book Principles of Bacterial Pathogenesis written by Eduardo A. Groisman and published by Academic Press. This book was released on 2001-01-09 with total page 863 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bacterial Pathogenesis presents a molecular perspective on a select group of bacterial pathogens by having the leaders of the field present their perspective in a clear and authoritative manner. Each chapter contains a comprehensive review devoted to a single pathogen. Several chapters include work from authors outside the pathogenesis field, providing general perspectives on the evolution, regulation, and secretion of virulence and determinants. Explains the basic principles of bacterial pathogenesis Covers diverse aspects integrating regulation, cellular microbiology and evolution of microbial disease of humans Discusses current strategies for the identification of virulence determinants and the methods used by microbes to deliver virulence factors Presents authoritative treatises of the major disease microorganisms
Download or read book Microbial Virulence Factors written by Jorge H Leitão and published by . This book was released on 2020-09-04 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease. This broad definition comprises secreted products such as toxins, enzymes, exopolysaccharides, as well as cell surface structures such as capsules, lipopolysaccharides, glyco- and lipoproteins. Intracellular changes in metabolic regulatory networks, governed by protein sensors/regulators and non-coding regulatory RNAs, are also known to contribute to virulence. Furthermore, some secreted microbial products have the ability to enter the host cell and manipulate their machinery, contributing to the success of the infection. The knowledge, at the molecular level, of the biology of microbial pathogens and their virulence factors is central in the development of novel therapeutic molecules and strategies to combat microbial infections. The present collection comprises state of the art research and review papers on virulence factors and mechanisms of a wide range of bacterial and fungal pathogens for humans, animals, and plants, thus reflecting the impact of microorganisms in health and economic human activities, and the importance of the topic.
Download or read book Pathogenesis of Bacterial Infections in Animals written by Carlton L. Gyles and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This much-anticipated third edition again consolidates the knowledge of more than twenty experts on pathogenesis of animal disease caused by various species or groups of bacteria. Emphasizing pathogenic events at the molecular and cellular levels, the editors and contributors place these developments in the context of the overall picture of disease. Pathogenesis of Bacterial Infections in Animals, Third edition, updates and expands the content of the second edition and includes cutting-edge information from the most current research. Comments on previous editions: "...highly recommended." --The Veterinary Record "...a comprehensive, complete and easy-to-use source of information." --Veterinary Microbiology "...recommended for graduate students and specialists in microbiology, pathology and infectious disease." --U.S. Animal Health Association Newsletter "...a wonderful book." --Journal of the American Veterinary Medical Association "...highly recommended." --The Cornell Veterinarian Graduate students, faculty, researchers, and specialists in microbiology, pathology, and infectious diseases will benefit from this highly-detailed and expanded edition of a popular and well-read veterinary text.
Download or read book Bacterial Pathogenomics written by Mark J. Pallen and published by . This book was released on 2007 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This landmark volume details progress in the fast-changing world of bacterial genomics and it includes contributions from a team of over forty world-renowned authors.
Download or read book Clinical Management of Complicated Urinary Tract Infection written by Ahmad Nikibakhsh and published by BoD – Books on Demand. This book was released on 2011-09-06 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complicated urinary tract infections (cUTIs) are a major cause of hospital admissions and are associated with significant morbidity and health care costs. Knowledge of baseline risk of urinary tract infection can help clinicians make informed diagnostic and therapeutic decisions. Prevalence rates of UTI vary by age, gender, race, and other predisposing risk factors. In this regard, this book provides comprehensive information on etiology, epidemiology, immunology, pathology, pathogenic mechanisms, symptomatology, investigation and management of urinary tract infection. Chapters cover common problems in urinary tract infection and put emphasis on the importance of making a correct clinical decision and choosing the appropriate therapeutic approach. Topics are organized to address all of the major complicated conditions frequently seen in urinary tract infection. The authors have paid particular attention to urological problems like the outcome of patients with vesicoureteric reflux, the factors affecting renal scarring, obstructive uropathy, voiding dysfunction and catheter associated problems. This book will be indispensable for all professionals involved in the medical care of patients with urinary tract infection.
Download or read book The Pangenome written by Hervé Tettelin and published by Springer Nature. This book was released on 2020-04-30 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
Download or read book Applied Genomics of Foodborne Pathogens written by Xiangyu Deng and published by Springer. This book was released on 2017-01-23 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a timely and thorough snapshot into the emerging and fast evolving area of applied genomics of foodborne pathogens. Driven by the drastic advance of whole genome shot gun sequencing (WGS) technologies, genomics applications are becoming increasingly valuable and even essential in studying, surveying and controlling foodborne microbial pathogens. The vast opportunities brought by this trend are often at odds with the lack of bioinformatics know-how among food safety and public health professionals, since such expertise is not part of a typical food microbiology curriculum and skill set. Further complicating the challenge is the large and ever evolving body of bioinformatics tools that can obfuscate newcomers to this area. Although reviews, tutorials and books are not in short supply in the fields of bioinformatics and genomics, until now there has not been a comprehensive and customized source of information designed for and accessible to microbiologists interested in applying cutting-edge genomics in food safety and public health research. This book fills this void with a well-selected collection of topics, case studies, and bioinformatics tools contributed by experts at the forefront of foodborne pathogen genomics research.
Download or read book Next Generation Probiotics From Commensal Bacteria to Novel Drugs and Food Supplements written by Philippe Langella and published by Frontiers Media SA. This book was released on 2019-11-22 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Farm Animals Diseases Recent Omic Trends and New Strategies of Treatment written by Rosa Estela Quiroz Castañeda and published by BoD – Books on Demand. This book was released on 2018-03-21 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scope of this book is to present the most recent trends based on omic analyses of microorganisms causing diseases in farm animals and how these approaches result in new strategies of treatment. The topics in this book include fasciolosis, avian coccidiosis, bovine anaplasmosis, tick-borne diseases, and babesiosis, among others. This book presents the recent advances in the omic field with an emphasis on how these analyses have led researchers to know the mechanisms that pathogens use to invade and colonize the host cell of farm animals. In this way, new treatments of control and prevention can be employed.
Download or read book The Science and Applications of Microbial Genomics written by Institute of Medicine and published by National Academies Press. This book was released on 2013-05-02 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past several decades, new scientific tools and approaches for detecting microbial species have dramatically enhanced our appreciation of the diversity and abundance of the microbiota and its dynamic interactions with the environments within which these microorganisms reside. The first bacterial genome was sequenced in 1995 and took more than 13 months of work to complete. Today, a microorganism's entire genome can be sequenced in a few days. Much as our view of the cosmos was forever altered in the 17th century with the invention of the telescope, these genomic technologies, and the observations derived from them, have fundamentally transformed our appreciation of the microbial world around us. On June 12 and 13, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to discuss the scientific tools and approaches being used for detecting and characterizing microbial species, and the roles of microbial genomics and metagenomics to better understand the culturable and unculturable microbial world around us. Through invited presentations and discussions, participants examined the use of microbial genomics to explore the diversity, evolution, and adaptation of microorganisms in a wide variety of environments; the molecular mechanisms of disease emergence and epidemiology; and the ways that genomic technologies are being applied to disease outbreak trace back and microbial surveillance. Points that were emphasized by many participants included the need to develop robust standardized sampling protocols, the importance of having the appropriate metadata, data analysis and data management challenges, and information sharing in real time. The Science and Applications of Microbial Genomics summarizes this workshop.
Download or read book Global Antimicrobial Resistance Surveillance System written by World Health Organization and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In May 2015, the Sixty-eighth World Health Assembly adopted the Global action plan on antimicrobial resistance, which reflects the global consensus that AMR poses a profound threat to human health. One of the five strategic objectives of the Global action plan is to strengthen the evidence base through enhanced global surveillance and research. The Global Antimicrobial Resistance Surveillance System (GLASS) has been developed to facilitate and encourage a standardized approach to AMR surveillance globally and in turn support the implementation of the Global action plan on antimicrobial resistance. This manual addresses the early phase of implementation of GLASS, focussing on surveillance of resistance in common human bacterial pathogens. The intended readership of this publication is public health professionals and health authorities responsible for national AMR surveillance. It outlines the GLASS standards and describes the road map for implementation of the system between 2015 and 2019. Further development of GLASS will be based on the lessons learnt during this period"--Publisher's description.
Download or read book The Evolving Threat of Antimicrobial Resistance written by World Health Organization and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotic resistance development is a natural process of adaption leading to a limited lifespan of antibiotics. Unnecessary and inappropriate use of antibiotics favours the emergence and spread of resistant bacteria. A crisis has been building up over decades, so that today common and life-threatening infections are becoming difficult or even impossible to treat. It is time to take much stronger action worldwide to avert an ever increasing health and economic burden. A new WHO publication "The evolving threat of antimicrobial resistance--Options for action" describes examples of policy activities that have addressed AMR in different parts of the world. The aim is to raise awareness and to stimulate further coordinated efforts.
