Download or read book Biologics and Biosimilars written by Xiaodong Feng and published by CRC Press. This book was released on 2022-06-13 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biologics and Biosimilars: Drug Discovery and Clinical Applications is a systematic integration and evaluation of all aspects of biologics and biosimilars, encompassing research and development, clinical use, global regulation, and more. Biosimilars are biological therapeutic agents designed to imitate a reference biologic with high similarities in structure, efficacy, and safety, but also with potential clinical effective and cost-efficient options for the manufacturers, payers, clinicians, and patients. Most of the top-selling prescription drugs in the current market are biologics, which have revolutionized the treatment strategies and modalities for life-threatening and/or rare diseases. This book outlines the key processes and challenges in drug development, regulations, and clinical applications of biologics, biosimilars, and even interchangeable biosimilars. Global experts in the field discuss essential categories and prototype drugs of biologics and biosimilars in clinical practice such as allergenics, blood and blood components, cell treatment, gene therapy, recombinant therapeutic proteins or peptides, tissues, and vaccines. Additional features: Integrates the latest bench and bedside evidence of drug development and regulations of biologics and biosimilars Contains key study questions for each chapter to guide the readers, as well as drug charts for all therapeutic applications of biologics and biosimilars Presents detailed schematic illustrations to explain the drug development, clinical trials, regulations, and clinical applications of biologics and biosimilars This book is an invaluable tool for health care professional students, providers, and pharmaceutical and health care industries, as well as the public, providing readers with educational updates about the drug development and clinical affairs of biological medications and their similar drugs.

Download or read book New trends for innovation in the Mediterranean animal production written by R. Bouche and published by Springer Science & Business Media. This book was released on 2012-03-26 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mediterranean area shows a great diversity of livestock systems, depending on local resources and traditions, but also on the networking space where informational resources are available for producers. During the last decades, a lot of innovations have been conceived or introduced in the Mediterranean area, allowing livestock systems to remain competitive. The book looks at two main issues: firstly, it gives an updated review on the main innovations that significantly changed the activities of livestock production in the Mediterranean area in the recent past. Secondly, the focus lies on the extent to which these innovations improve the efficiency, ensure the socio-cultural basis or reduce the environmental impact of livestock systems. One major finding is a new vision of innovating systems based on the distinction between regulated innovation (when aims are fixed) and innovative design (when aims are questioned). Innovations reported in the book are dealing with a set of concerns. They concern the production techniques, the work organization, the equipment and infrastructures, the collective features for selection, reproduction, feeding or sanitary devices. They also concern the local organization such as product labelling, new dynamics around local breeds, collective rules for supply basin or approaches of new products for new markets. More recently, some innovations focus on environmental impacts of livestock production, due to an increasing consciousness of those kinds of problems. In the final part of the book, a round table copes with a crucial question: are traditions in Mediterranean livestock activities to be considered an obstacle or a source of innovation? This book provides a set of updated information and knowledge useful for researchers, students, extension services and policy-makers in the field of animal science.

Download or read book Capital written by Carl Marx and published by Createspace Independent Publishing Platform. This book was released on 2018-04 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written: in draft by Marx 1863-1878, edited for publication by Engels; First published: in German in 1885, authoritative revised edition in 1893; Source: First English edition of 1907; Published: Progress Publishers, Moscow, 1956, USSR.

Download or read book The Geography of Innovation written by M.P. Feldman and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a geographic dimension to the study of innovation and product commercialization. Building on the literature in economics and geography, this book demonstrates that product innovation clusters spatially in regions which provide concentrations of the knowledge needed for the commercialization process. The book develops a conceptual model which links the location of new product innovations to the sources of these knowledge inputs. The geographic concentration of this knowledge fonns a technological infrastructure which promotes infonnation transfers, and lowers the risks and the costs of engaging in innovative activity. Empirical estimation confinns that the location of product innovation is related to the underlying technological infrastructure, and that the location of the knowledge inputs are mutually reinforcing in defining a region's competitive advantage. The book concludes by considering the policy implications of these fmdings for both private finns and state governments. This work is intended for academics, policy practitioners and students in the fields of innovation and technological change, geography and regional science, and economic development. This work is part of a larger research effort to understand why the location of innovative activity varies spatially, specifically the externalities and increasing returns which accrue to location. xi Acknowledgements This work has benefitted greatly from discussions with friends and colleagues. I wish to specifically note the contribution of Mark Kamlet, Wes Cohen, Richard Florida, Zoltan Acs and David Audretsch. I would like to thank Gail Cohen Shaivitz for her dedication in editing the final manuscript.

Download or read book Advances in Cephalopod Science Biology Ecology Cultivation and Fisheries written by and published by Academic Press. This book was released on 2014-05-26 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cephalopod Science: Biology, Ecology, Cultivation and Fisheries—volume 67 in the Advances in Marine Biology series—addresses major themes of growing research interest in the field of cephalopod research. The book is composed of four chapters incorporating the latest advances in biology, ecology, life cycles, cultivation, and fisheries of cephalopods. Each chapter is written by a team of internationally recognized authorities to reflect recent findings and understanding. The book represents a breakthrough contribution to the field of cephalopod science. Advances in Marine Biology was first published in 1963 under the founding editorship of Sir Frederick S. Russell, FRS. Now edited by Michael P. Lesser, with an internationally renowned editorial board, the serial publishes in-depth and up-to-date reviews on a wide range of topics that appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology, and biological oceanography. Eclectic volumes in the series are supplemented by thematic volumes on such topics as the biology of calanoid copepods. - Covers cephalopod culture - Covers environmental effects on cephalopod population dynamics - Covers biology, ecology and biodiversity of deep-sea cephalopods - Covers life stage transitions in successful cephalopod life strategies

Download or read book Psychiatry written by Konstantinos N. Fountoulakis and published by Springer Nature. This book was released on 2021-11-26 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was the end product of life experiences, thoughts and intellectual wanderings of the author, who through his career and for the last twenty years was always serving all the three aspects of a Psychiatrist: He is a clinician, a researcher and an academic teacher. The book includes a comprehensive history of Psychiatry since antiquity and until today, with an emphasis not only on main events but also specifically and with much detail and explanations, on the chain of events that led to a particular development. At the center of this work is the question ‘What is mental illness?’ and ‘Does free will exist?’. These are questions which tantalize Psychiatrists, neuroscientists, psychologists, philosophers, patients and their families and the sensitive and educated lay persons alike. Thus, the book includes a comprehensive review and systematic elaboration on the definition and the concept of mental illness, a detailed discussion on the issue of free will as well as the state of the art of contemporary Psychiatry and the socio-political currents it has provoked. Finally the book includes a description of the academic, social and professional status of Psychiatry and Psychiatrists and a view of future needs and possible developments. A last moment addition was the chapter on conspiracy theories, as a consequence of the experience with the social media and the public response to the COVID-19 outbreak which coincided with the final stage of the preparation of the book. Their study is an excellent opportunity to dig deep into the relation among human psychology, mental health, the society and politics and to swim in intellectually dangerous waters.

Download or read book Report written by Science Council of Canada and published by . This book was released on 1983 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Art in the Age of Machine Learning written by Sofian Audry and published by MIT Press. This book was released on 2021-11-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: An examination of machine learning art and its practice in new media art and music. Over the past decade, an artistic movement has emerged that draws on machine learning as both inspiration and medium. In this book, transdisciplinary artist-researcher Sofian Audry examines artistic practices at the intersection of machine learning and new media art, providing conceptual tools and historical perspectives for new media artists, musicians, composers, writers, curators, and theorists. Audry looks at works from a broad range of practices, including new media installation, robotic art, visual art, electronic music and sound, and electronic literature, connecting machine learning art to such earlier artistic practices as cybernetics art, artificial life art, and evolutionary art. Machine learning underlies computational systems that are biologically inspired, statistically driven, agent-based networked entities that program themselves. Audry explains the fundamental design of machine learning algorithmic structures in terms accessible to the nonspecialist while framing these technologies within larger historical and conceptual spaces. Audry debunks myths about machine learning art, including the ideas that machine learning can create art without artists and that machine learning will soon bring about superhuman intelligence and creativity. Audry considers learning procedures, describing how artists hijack the training process by playing with evaluative functions; discusses trainable machines and models, explaining how different types of machine learning systems enable different kinds of artistic practices; and reviews the role of data in machine learning art, showing how artists use data as a raw material to steer learning systems and arguing that machine learning allows for novel forms of algorithmic remixes.

Download or read book Cephalopod Culture written by José Iglesias and published by Springer Science & Business Media. This book was released on 2014-03-26 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cephalopod Culture is the first compilation of research on the culture of cephalopods. It describes experiences of culturing different groups of cephalopods: nautiluses, sepioids (Sepia officinalis, Sepia pharaonis, Sepiella inermis, Sepiella japonica Euprymna hyllebergi, Euprymna tasmanica), squids (Loligo vulgaris, Doryteuthis opalescens, Sepioteuthis lessoniana) and octopods (Amphioctopus aegina, Enteroctopus megalocyathus, Octopus maya, Octopus mimus, Octopus minor, Octopus vulgaris, Robsonella fontaniana). It also includes the main conclusions which have been drawn from the research and the future challenges in this field. This makes this book not only an ideal introduction to cephalopod culture, but also a valuable resource for those already involved in this topic.

Download or read book Agrindex written by and published by . This book was released on 1991 with total page 1546 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Bioinformatics For Dummies written by Jean-Michel Claverie and published by John Wiley & Sons. This book was released on 2011-02-10 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Were you always curious about biology but were afraid to sit through long hours of dense reading? Did you like the subject when you were in high school but had other plans after you graduated? Now you can explore the human genome and analyze DNA without ever leaving your desktop! Bioinformatics For Dummies is packed with valuable information that introduces you to this exciting new discipline. This easy-to-follow guide leads you step by step through every bioinformatics task that can be done over the Internet. Forget long equations, computer-geek gibberish, and installing bulky programs that slow down your computer. You’ll be amazed at all the things you can accomplish just by logging on and following these trusty directions. You get the tools you need to: Analyze all types of sequences Use all types of databases Work with DNA and protein sequences Conduct similarity searches Build a multiple sequence alignment Edit and publish alignments Visualize protein 3-D structures Construct phylogenetic trees This up-to-date second edition includes newly created and popular databases and Internet programs as well as multiple new genomes. It provides tips for using servers and places to seek resources to find out about what’s going on in the bioinformatics world. Bioinformatics For Dummies will show you how to get the most out of your PC and the right Web tools so you'll be searching databases and analyzing sequences like a pro!

Download or read book Capital written by Karl Marx and published by Penguin UK. This book was released on 1990 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "forgotten" second volume of Capital, Marx's world-shaking analysis of economics, politics, and history, contains the vital discussion of commodity, the cornerstone to Marx's theories.

Download or read book Vitiligo and Other Hypomelanoses of Hair and Skin written by Jean-Paul Ortonne and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukoderma is a generic term for any pigmentary dilution, be it congenital or acquired, circumscribed or generalized, devoid of or partially lacking in pig mentation. In the approach to the diagnosis of leukoderma, we have generally first considered the age of onset, whether leukoderma was congenital or ac quired, the extent and pattern of involvement, and the degree of pigmentary dilution. The organization of this monograph reflects this approach. For ex ample, we have separated the section devoted to various disease entities into diffuse and circumscribed leukoderma and the latter into various etiologies such as genetic, metabolic, infectious, and endocrinologic. One of several justifications for this monograph is to present an approach to the diagnosis of leukoderma, as detailed in Part II. In formulating a guide for the physician, we have found some limitations to our previous approach; we therefore offer the following new classification based upon a clini cal-pathologic correlation. This could provide the means to describe both the clinical and pathologic findings in one term.

Download or read book Microorganisms in the Deterioration and Preservation of Cultural Heritage written by Edith Joseph and published by Springer Nature. This book was released on 2021-05-05 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers a comprehensive overview of the role and potential of microorganisms in the degradation and preservation of cultural materials (e.g. stone, metals, graphic documents, textiles, paintings, glass, etc.). Microorganisms are a major cause of deterioration in cultural artefacts, both in the case of outdoor monuments and archaeological finds. This book covers the microorganisms involved in biodeterioration and control methods used to reduce their impact on cultural artefacts. Additionally, the reader will learn more about how microorganisms can be used for the preservation and protection of cultural artefacts through bio-based and eco-friendly materials. New avenues for developing methods and materials for the conservation of cultural artefacts are discussed, together with concrete advances in terms of sustainability, effectiveness and toxicity, making the book essential reading for anyone interested in microbiology and the preservation of cultural heritage.

Download or read book Annual Report Science Council of Canada written by Science Council of Canada and published by . This book was released on 1984 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes list of publications of the Science Council of Canada.

Download or read book A Bibliography of Fishes written by Bashford Dean and published by . This book was released on 1916 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fran ois Hotman Antitribonian written by and published by BRILL. This book was released on 2021-10-18 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written c. 1567 (though unpublished until 1603), this is the work of an extraordinary scholar, a radical and polemicist, rival of many of the leading intellectual and political figures of his day. According to François Hotman’s distinguished biographer Donald Kelley the Antitribonian ‘is, or should be, a landmark in the history of social and historical thought’. It is also a landmark in the history of legal thought. The present edition is the first to evaluate Hotman’s text in the context of the history of Roman law from the time of the sixth-century Byzantine Emperor Justinian I to the Germany of the Enlightenment.