Download or read book Integration of Process Incompatible Materials for Microfabricated Polymer Based Neural Interfaces written by Allison Elizabeth Hess and published by . This book was released on 2011 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation presents the development of microfabrication processes for the integration of process-incompatible, dissimilar materials in MEMS devices with application to neural interfaces for long-term implantation. Micromachining techniques were developed for a novel, mechanically-dynamic, chemo-responsive polymer nanocomposite based on a poly(vinyl acetate) matrix with embedded cellulose nanofibers designed to address issues related to the mechanical mismatch between the neural probe and cortical tissue. Microtensile testing was performed to assess the mechanical properties of laser-patterned nanocomposite microstructures. Within 3-7 minutes of immersion in DI water, the nanocomposite displayed a reduction in Young's modulus by a factor of 140-200, from 1.2-3.4 GPa to 4.9-22 MPa, depending upon the cellulose nanofiber source and concentration. A comparable reduction in Young's modulus was measured for samples that had been implanted in a rat cortex, suggesting this material can penetrate through the pia without buckling, but then softens and better matches the mechanics of cortical tissue. A process utilizing a parylene moisture barrier was developed to fabricate nanocomposite-based intracortical probes with integrated thin-film metal electrodes and interconnects. The electrode impedance was found to be 95.0 + 4.8 k[omega] for an electrode 6000 [mu]m^2 in area. To develop a microfabricated neural array technology with on-board recording, stimulation and chemical sensing capabilities, a process was developed to integrate semi-metallic diamond microelectrodes into a flexible polymer substrate. Diamond-on-polymer microelectrode arrays were fabricated using a "diamond-first" fabrication process whereby the diamond electrodes were first grown on a Si/SiO2 substrate, followed by the deposition and patterning of a polynorbornene capping layer, thin-film metal interconnects, and a polynorbornene substrate layer. A chemical release process in 49% HF was used to transfer the diamond from the Si substrate to the polymer substrate. Ohmic contact was made to diamond microelectrodes using Cr/Au metallization, without requiring an annealing step. Current pulse testing demonstrated potential for neural stimulation with diamond microelectrodes. The electrode impedance at 1 kHz was found to range from 300 k[omega] to 8 M[omega], indicating that there are some electrodes suitable for neural recording. Finally, electrochemical detection of 100 [mu]M dopamine in saline was achieved with a diamond-on-polymer electrode.

Download or read book The Essential Handbook of Polymer Terms and Attributes written by Munmaya K Mishra and published by CRC Press. This book was released on 2024-07-30 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Essential Handbook of Polymer Terms and Attributes not only acts as an encyclopaedia of polymer science but also fosters an appreciation for the significance of polymers in fields including materials science, chemistry, engineering, and medicine. This book serves as an excellent reference book, covering every possible term and attribution associated with the vast and diverse field of polymers. This comprehensive volume serves as a vital resource for researchers working in industry and academia, offering a clear and concise exploration of polymer science with the most essential reference data available. Each polymer term is defined in a straightforward manner, ensuring that readers of all levels can grasp the concepts. The book goes beyond mere definitions, providing context and insights into the applications, properties, and synthesis. Bringing polymer terms and attributes together in one place, the book provides a broad knowledge of polymer science and facilitates idea generation for researchers and students embarking on projects related to a specific field of polymer science. Key features: This book covers all possible terms associated with the field of “polymers" and related areas, granting readers a comprehensive understanding of the entire spectrum of polymers. The organization of the book follows an alphabetical format, enabling quick and convenient access to specific terms. Each polymer term is clearly defined with a figure or scheme as needed, allowing readers to visualize the structures, processes, and applications involved. This book is written for science students, chemists, polymer scientists, chemical engineers, pharmaceutical scientists, biomedical scientists, biotechnologists, product formulators, materials scientists, and scientists working on polymers.

Download or read book Handbook Of Biomimetics And Bioinspiration Biologically driven Engineering Of Materials Processes Devices And Systems In 3 Volumes written by Esmaiel Jabbari and published by World Scientific. This book was released on 2014-04-29 with total page 1462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global warming, pollution, food and water shortage, cyberspace insecurity, over-population, land erosion, and an overburdened health care system are major issues facing the human race and our planet. These challenges have presented a mandate to develop “natural” or “green” technologies using nature and the living system as a guide to rationally design processes, devices, and systems. This approach has given rise to a new paradigm, one in which innovation goes hand-in-hand with less waste, less pollution, and less invasiveness to life on earth. Bioinspiration has also led to the development of technologies that mimic the hierarchical complexity of biological systems, leading to novel highly efficient, more reliable multifunctional materials, devices, and systems that can perform multiple tasks at one time. This multi-volume handbook focuses on the application of biomimetics and bioinspiration in medicine and engineering to produce miniaturized multi-functional materials, devices, and systems to perform complex tasks. Our understanding of complex biological systems at different length scales has increased dramatically as our ability to observe nature has expanded from macro to molecular scale, leading to the rational biologically-driven design to find solution to technological problems in medicine and engineering.The following three-volume set covers the fields of bioinspired materials, electromechanical systems developed from concepts inspired by nature, and tissue models respectively.The first volume focuses on the rational design of nano- and micro-structured hierarchical materials inspired by the relevant characteristics in living systems, such as the self-cleaning ability of lotus leaves and cicadas' wings; the superior walking ability of water striders; the anti-fogging function of mosquitoes' eyes; the water-collecting ability of Namib Desert Beetles and spider silk; the high adhesivity of geckos' feet and rose petals; the high adhesivity of mussels in wet aquatic environments; the anisotropic wetting of butterflies' wings; the anti-reflection capabilities of cicadas' wings; the self-cleaning functionality of fish scales; shape anisotropy of intracellular particles; the dielectric properties of muscles; the light spectral characteristics of plant leaves; the regeneration and self-healing ability of earthworms; the self-repairing ability of lotus leaves; the broadband reflectivity of moths' eyes; the multivalent binding, self-assembly and responsiveness of cellular systems; the biomineral formation in bacteria, plants, invertebrates, and vertebrates; the multi-layer structure of skin; the organization of tissue fibers; DNA structures with metal-mediated artificial base pairs; and the anisotropic microstructure of jellyfish mesogloea. In this volume, sensor and microfluidic technologies combined with surface patterning are explored for the diagnosis and monitoring of diseases. The high throughput combinatorial testing of biomaterials in regenerative medicine is also covered.The second volume presents nature-oriented studies and developments in the field of electromechanical devices and systems. These include actuators and robots based on the movement of muscles, algal antenna and photoreception; the non-imaging light sensing system of sea stars; the optical system of insect ocellus; smart nanochannels and pumps in cell membranes; neuromuscular and sensory devices that mimic the architecture of peripheral nervous system; olfaction-based odor sensing; cilia-mimetic microfluidic systems; the infrared sensory system of pyrophilous insects; ecologically inspired multizone temperature control systems; cochlea and surface acoustic wave resonators; crickets' cercal system and flow sensing abilities; locusts' wings and flapping micro air vehicles; the visual motion sensing of flying insects; hearing aid devices based on the human cochlea; the geometric perception of tortoises and pigeons; the organic matter sensing capability of cats and dogs; and the silent flight of rats. The third volume features engineered models of biological tissues. These include engineered matrices to mimic cancer stem cell niches; in vitro models for bone regeneration; models of muscle tissue that enable the study of cardiac infarction and myopathy; 3D models for the differentiation of embryonic stem cells; bioreactors for in vitro cultivation of mammalian cells; human lung, liver and heart tissue models; topographically-defined cell culture models; ECM mimetic tissue printing; biomimetic constructs for regeneration of soft tissues; and engineered constructs for the regeneration of musculoskeletal and corneal tissue.This three-volume set is a must-have for anyone keen to understand the complexity of biological systems and how that complexity can be mimicked to engineer novel materials, devices and systems to solve pressing technological challenges of the twenty-first century.Key Features:The only handbook that covers all aspects of biomimetics and bioinspiration, including materials, mechanics, signaling and informaticsContains 248 colored figures

Download or read book Microscale and Nanoscale Neural Interfaces written by Karen Chihmin Cheung and published by . This book was released on 2002 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Biomimetics and Bioinspiration written by Esmaiel Jabbari and published by World Scientific. This book was released on 2014 with total page 1462 pages. Available in PDF, EPUB and Kindle. Book excerpt: self-assembly and responsiveness of cellular systems; the biomineral formation in bacteria, plants, invertebrates, and vertebrates; the multi-layer structure of skin; the organization of tissue fibers; DNA structures with metal-mediated artificial base pairs; and the anisotropic microstructure of jellyfish mesogloea. In this volume, sensor and microfluidic technologies combined with surface patterning are explored for the diagnosis and monitoring of diseases. The high throughput combinatorial testing of biomaterials in regenerative medicine is also covered. The second volume presents nature-oriented studies and developments in the field of electromechanical devices and systems.

Download or read book Implantable Bioelectronics written by Evgeny Katz and published by John Wiley & Sons. This book was released on 2014-02-27 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here the renowned editor Evgeny Katz has chosen contributions that cover a wide range of examples and issues in implantable bioelectronics, resulting in an excellent overview of the topic. The various implants covered include biosensoric and prosthetic devices, as well as neural and brain implants, while ethical issues, suitable materials, biocompatibility, and energy-harvesting devices are also discussed. A must-have for both newcomers and established researchers in this interdisciplinary field that connects scientists from chemistry, material science, biology, medicine, and electrical engineering.

Download or read book Bridging the Gap in Neuroelectronic Interfaces written by Jeffrey R. Capadona and published by Frontiers Media SA. This book was released on 2020-07-09 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Carbon The Next Silicon written by Marc J. Madou and published by Momentum Press. This book was released on 2016-01-12 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear Magnetic Resonance (NMR) and Electron Spin Resonance (ESR) spectroscopies are well-known characterization techniques that reveal the molecular details of a sample non-invasively. The authors discuss how NMR can provide useful information on the microstructure of carbon and its surface properties and explain how C-MEMS/C-NEMS technology can be explored for building improved NMR microdevices. The authors highlight the manipulation of fluids and particles by dielectrophoresis and the use of carbon electrodes for dielectrophoresis in Lab-on-a-Chip. The use of these electrodes in sample preparation through electrical polarization of a sample for identification, manipulation, and lysis of bioparticles is also discussed and they introduce a new generation of neural prosthetics based on glassy carbon micromachined electrode arrays. The tuning of the electrical, electrochemical and mechanical properties of these patternable electrodes for applications in bio-electrical signal recording and stimulation, and results from in-vivo testing of these glassy carbon microelectrode arrays is reported, demonstrating a quantifiable superior performance compared to metal electrodes.

Download or read book High Performance Polymers written by Johannes Karl Fink and published by William Andrew. This book was released on 2014-07-04 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approaching the material from a chemistry and engineering perspective, High Performance Polymers presents the most reliable and current data available about state-of-the-art polymerization, fabrication, and application methods of high performance industrial polymers. Chapters are arranged according to the chemical constitution of the individual classes, beginning with main chain carbon-carbon polymers and leading to ether-containing, sulfur-containing, and so on. Each chapter follows an easily readable template, provides a brief overview and history of the polymer, and continues on to such sub-topics as monomers; polymerization and fabrication; properties; fabrication methods; special additives; applications; suppliers and commercial grades; safety; and environmental impact and recycling. High Performance Polymers brings a wealth of up-to-date, high performance polymer data to you library, in a format that allows for either a fast fact-check or more detailed study. In this new edition the data has been fully updated to reflect all developments since 2008, particularly in the topics of monomers, synthesis of polymers, special polymer types, and fields of application. - Presents the state-of-the-art polymerization, fabrication and application methods of high performance industrial polymers - Provides fundamental information for practicing engineers working in industries that develop advanced applications (including electronics, automotive and medical) - Discusses environmental impact and recycling of polymers

Download or read book Biomedical Microsystems written by Ellis Meng and published by CRC Press. This book was released on 2011-06-22 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poised to dramatically impact human health, biomedical microsystems (bioMEMS) technologies incorporate various aspects from materials science, biology, chemistry, physics, medicine, and engineering. Reflecting the highly interdisciplinary nature of this area, Biomedical Microsystems covers the fundamentals of miniaturization, biomaterials, microfabrication, and nanotechnology, along with relevant applications. Written by an active researcher who was recently named one of Technology Review’s Young Innovators Under 35, the book begins with an introduction to the benefits of miniaturization. It then introduces materials, fabrication technology, and the necessary components of all bioMEMS. The author also covers fundamental principles and building blocks, including microfluidic concepts, lab-on-a-chip systems, and sensing and detection methods. The final chapters explore several important applications of bioMEMS, such as microdialysis, catheter-based sensors, MEMS implants, neural probes, and tissue engineering. For readers with a limited background in MEMS and bioMEMS, this book provides a practical introduction to the technology used to make these devices, the principles that govern their operation, and examples of their application. It offers a starting point for understanding advanced topics and encourages readers to begin to formulate their own ideas about the design of novel bioMEMS. A solutions manual is available for instructors who want to convert this reference to classroom use.

Download or read book MEMS Materials and Processes Handbook written by Reza Ghodssi and published by Springer Science & Business Media. This book was released on 2011-03-18 with total page 1211 pages. Available in PDF, EPUB and Kindle. Book excerpt: MEMs Materials and Processes Handbook" is a comprehensive reference for researchers searching for new materials, properties of known materials, or specific processes available for MEMS fabrication. The content is separated into distinct sections on "Materials" and "Processes". The extensive Material Selection Guide" and a "Material Database" guides the reader through the selection of appropriate materials for the required task at hand. The "Processes" section of the book is organized as a catalog of various microfabrication processes, each with a brief introduction to the technology, as well as examples of common uses in MEMs.

Download or read book Smart Sensors for Health and Environment Monitoring written by Chong-Min Kyung and published by Springer. This book was released on 2015-07-22 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers two most important applications of smart sensors, namely bio-health sensing and environmental monitoring. The approach taken is holistic and covers the complete scope of the subject matter from the principles of the sensing mechanism, through device physics, circuit and system implementation techniques, and energy issues to wireless connectivity solutions. It is written at a level suitable mainly for post-graduate level researchers interested in practical applications. The chapters are independent but complementary to each other, and the book works within the wider perspective of essential smart sensors for the Internet of Things (IoT). This is the second of three books based on the Integrated Smart Sensors research project, which describe the development of innovative devices, circuits, and system-level enabling technologies. The aim of the project was to develop common platforms on which various devices and sensors can be loaded, and to create systems offering significant improvements in information processing speed, energy usage, and size. This book contains substantial reference lists and over 150 figures, introducing the reader to the subject in a tutorial style whilst also addressing state-of-the-art research results, allowing it to be used as a guide for starting researchers.

Download or read book Stretchable Bioelectronics for Medical Devices and Systems written by John A. Rogers and published by Springer. This book was released on 2016-03-31 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights recent advances in soft and stretchable biointegrated electronics. A renowned group of authors address key ideas in the materials, processes, mechanics, and devices of soft and stretchable electronics; the wearable electronics systems; and bioinspired and implantable biomedical electronics. Among the topics discussed are liquid metals, stretchable and flexible energy sources, skin-like devices, in vitro neural recording, and more. Special focus is given to recent advances in extremely soft and stretchable bio-inspired electronics with real-world clinical studies that validate the technology. Foundational theoretical and experimental aspects are also covered in relation to the design and application of these biointegrated electronics systems. This is an ideal book for researchers, engineers, and industry professionals involved in developing healthcare devices, medical tools and related instruments relevant to various clinical practices.

Download or read book The Chemistry of Inorganic Biomaterials written by Christopher Spicer and published by Royal Society of Chemistry. This book was released on 2021-08-18 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book overviews the underlying chemistry behind the most common and cutting-edge inorganic materials in current use, or approaching use, in vivo.

Download or read book BioMEMS written by Simona Badilescu and published by CRC Press. This book was released on 2016-04-19 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written to cover often overlooked areas in the field of bioMEMS, this volume bridges topics related to biomolecules and complex biological entities with those directly related to the design, fabrication, and characterization of the devices. Unlike other references, this text aids with the fundamental physicochemical understanding of biological processes relevant to the performance of various biosensing devices. Accessible to seniors and graduate students enrolled in engineering programs, the book includes problems in each chapter as well as case studies to provide real-life examples.

Download or read book Ultra thin Chip Technology and Applications written by Joachim Burghartz and published by Springer Science & Business Media. This book was released on 2010-11-18 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultra-thin chips are the "smart skin" of a conventional silicon chip. This book shows how very thin and flexible chips can be fabricated and used in many new applications in microelectronics, Microsystems, biomedical and other fields. It provides a comprehensive reference to the fabrication technology, post processing, characterization and the applications of ultra-thin chips.

Download or read book Neural Interface Engineering written by Liang Guo and published by Springer Nature. This book was released on 2020-05-04 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive reference to major neural interfacing technologies used to transmit signals between the physical world and the nervous system for repairing, restoring and even augmenting body functions. The authors discuss the classic approaches for neural interfacing, the major challenges encountered, and recent, emerging techniques to mitigate these challenges for better chronic performances. Readers will benefit from this book’s unprecedented scope and depth of coverage on the technology of neural interfaces, the most critical component in any type of neural prostheses. Provides comprehensive coverage of major neural interfacing technologies; Reviews and discusses both classic and latest, emerging topics; Includes classification of technologies to provide an easy grasp of research and trends in the field.