Download or read book Insights in cushing s syndrome and disease written by Francesco Doglietto and published by Frontiers Media SA. This book was released on 2023-01-03 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cushing s Syndrome written by Marcello D. Bronstein and published by Springer Science & Business Media. This book was released on 2010-10-01 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cushing ́s syndrome is a relatively rare clinical disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function and growth impairment in children, all of which severely reduce quality of life and life expectancy. Cushing’s Syndrome: Pathophysiology, Diagnosis and Treatment reviews the difficulties in distinguishing Cushing’s syndrome from these and other common conditions, such as central obesity, menstrual irregularity and depression. It also provides state-of-the-art information on various strategies to establish the diagnosis of Cushing’s syndrome and the differential diagnosis among its diverse etiologies, as well as therapeutic approaches. Additionally, a range of conditions that represent challenges for the diagnosis and treatment--such as renal failure, pediatric age, cyclic hypercortisolism, and pregnancy--are covered in detail. A valuable resource not only for endocrinologists but also internal medicine physicians, gynecologists, pediatricians, , pituitary surgeons and urologists, Cushing’s Syndrome: Pathophysiology, Diagnosis and Treatment provides insights by experts that will help all physicians dealing with Cushing ́s syndrome to expand their knowledge about the condition and provide targeted, comprehensive care.
Download or read book Cushing Syndrome New Insights for the Healthcare Professional 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 65 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cushing Syndrome: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Cushing Syndrome in a concise format. The editors have built Cushing Syndrome: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cushing Syndrome in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cushing Syndrome: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Cushing s Syndrome New Insights for the Healthcare Professional 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cushing’s Syndrome: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Diagnosis and Screening in a concise format. The editors have built Cushing’s Syndrome: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cushing’s Syndrome: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Cushing s Syndrome New Insights for the Healthcare Professional 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cushing's Syndrome: New Insights for the Healthcare Professional: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Cushing Syndrome in a compact format. The editors have built Cushing's Syndrome: New Insights for the Healthcare Professional: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cushing Syndrome in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cushing's Syndrome: New Insights for the Healthcare Professional: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Cushing s Disease written by Edward R. Laws Jr and published by Academic Press. This book was released on 2016-11-08 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cushing's Disease: An Often Misdiagnosed and Not So Rare Disorder reviews the epidemiology of Cushing's, including statistics on the incidence and prevalence of this disease. There are discussions of the signs and symptoms and the most common co-morbidities, such as diabetes mellitus, hypertension, osteoporosis, amenorrhea, and infertility. Surgical, medical, and radiotherapeutic treatments, including indications, results, risks, and complications, are reviewed. Also featured is a chapter on the patient's perspective, coping with Cushing's, quality of life, and psychosomatic issues. This book is essential reading for the wide range of physicians who treat patients with Cushing's disease symptoms, as well as biomedical researchers who investigate the etiology and mechanisms of rare genetic diseases, in particular rare endocrine disorders. - Reviews the basics of Cushing's disease and its interrelation with hormones, the brain, and bodily functions - Includes chapters on diagnosis, surgical, medical, and radiotherapeutic treatments, and variations in presentation, including cyclical disease - Presents the cognitive and emotional aspects of Cushing's and the long-term sequelae - Offers an important resource for physicians who are accustomed to treating individual symptoms rather than a disease complex - Reviews multidisciplinary management, and post-treatment management of Cushing's, including recommendations for Cushing's Centers of Excellence
Download or read book Novel Insights in the Management of Cushing s Syndrome written by Annamaria Colao and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue is a dedicated supplement published in addition to the regular issues of 'Neuroendocrinology' focussing on one specific topic. 'Neuroendocrinology' is a well-respected, international peer-reviewed journal in Endocrinology. Supplement issues are included in the subscription.
Download or read book Addison s Disease Vs Cushing s Symptoms Causes Treatment written by Recardim Smith Evalina and published by Independently Published. This book was released on 2024-07-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Navigate the complexities of two major endocrine disorders with Addison's Disease vs. Cushing's - Symptoms, Causes, Treatment. This comprehensive guide compares and contrasts Addison's disease and Cushing's syndrome, providing valuable insights into their symptoms, underlying causes, and treatment options. In this book, you'll explore: Symptoms: Understand the distinct and overlapping symptoms of Addison's disease and Cushing's syndrome. From the characteristic skin changes and fatigue in Addison's disease to the weight gain and hypertension in Cushing's syndrome, this book provides a detailed analysis to help differentiate between these conditions. Causes: Delve into the root causes of both disorders, including adrenal gland dysfunction in Addison's disease and excess cortisol production in Cushing's syndrome. The book explains the physiological and genetic factors that contribute to these conditions, offering a clear understanding of their origins. Diagnosis: Learn about the diagnostic criteria and tests used to identify Addison's disease and Cushing's syndrome. The book covers hormone level assessments, imaging studies, and other diagnostic tools, providing a comprehensive overview of how healthcare professionals distinguish between these disorders. Treatment: Explore the treatment strategies for managing Addison's disease and Cushing's syndrome. From hormone replacement therapy and surgical options to lifestyle modifications and supportive care, the book outlines the latest medical approaches to managing these complex conditions. Living with Endocrine Disorders: Gain practical advice on living with these conditions, including tips on managing symptoms, coping with emotional challenges, and maintaining overall health and wellness. The book also discusses the importance of ongoing medical monitoring and patient education. Addison's Disease vs. Cushing's - Symptoms, Causes, Treatment is an essential resource for patients, caregivers, and healthcare professionals. With clear explanations and practical guidance, this book equips readers with the knowledge needed to understand, diagnose, and manage these endocrine disorders effectively. Whether you're seeking information for yourself or a loved one, this book offers valuable insights into navigating the challenges of Addison's disease and Cushing's syndrome.
Download or read book Cushing s Syndrome written by Lewis S. Blevins and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cushing's Syndrome provides the reader with an update on the clinical presentation, diagnosis, and treatment of patients with Cushing's syndrome. Molecular mechanisms of pituitary and adrenal causes of Cushing's syndrome are reviewed in detail. Successful diagnostic and treatment strategies that have been employed by readers in the field are recommended and discussed. Numerous advances in the pathophysiology and diagnosis of Cushing's syndrome speak to the timeliness of this volume that has been penned by experts in the field.
Download or read book Cushing s Syndrome written by Dorothy T. Krieger and published by Springer. This book was released on 1982 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Glucocorticoid Signaling written by Jen-Chywan Wang and published by Springer. This book was released on 2015-07-27 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.
Download or read book The Hypothalamus Pituitary Adrenal Axis written by and published by Elsevier. This book was released on 2008-09-12 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. - Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle - Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later
Download or read book Pituitary Microadenomas written by G. Faglia and published by . This book was released on 1980 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.
Download or read book Cushing s disease and aggressive pituitary tumours written by Daniel Bengtsson and published by Linköping University Electronic Press. This book was released on 2021-04-07 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis focuses on clinical and epidemiological aspects of aggressive pituitary tumours/carcinomas and Cushing’s disease. Pituitary carcinomas account for only 0.1-0.2% of the tumours originating from the anterior pituitary gland and are defined solely by the event of distant metastases, whereas aggressive pituitary tumours are defined by their clinical behaviour of rapid/progressive growth despite optimal treatment with surgery, radiotherapy and medical agents. The prognosis for individuals with aggressive tumours/carcinomas has been poor with few treatment options. However, case reports indicated better outcomes after treatment with the alkylating agent temozolomide. In study I and III, we investigated 24 patients (16 aggressive tumours and 8 carcinomas) given treatment with temozolomide. We found an initial response rate (tumour regression ≥30%) in 10/21 evaluable patients, with complete regression in two carcinomas. Favourable response was associated with low tumour expression of the DNA repair protein MGMT; in responders median 9% (range 5-20%) vs non-responders median 93% (50-100%). Our results also indicated a longer survival in patients with low MGMT. Out of 11 patients with MGMT >10%, nine died with an estimated median survival of 26 months (95% CI 14-38), whereas only 1/6 patients with lower MGMT died from tumour progression during a follow-up of median 83 months (range 12-161). One of the patients in study I and III had a corticotroph pituitary carcinoma and in addition, Lynch syndrome (LS), a hereditary cancer-predisposing syndrome caused by germline mutations in DNA mismatch repair (MMR) genes and primarily associated with colon and endometrial carcinomas. In study II, we investigated the characteristics of the pituitary carcinoma and found loss of MSH2 and MSH6 protein expression, consistent with the patient’s germline mutation in MSH2. This was the first published case of a pituitary tumour associated with LS. In addition, we identified all known Swedish patients with LS (n=910) and searched for diagnostic codes consistent with a pituitary tumour in the Swedish national patient register. We found in total three patients with clinically relevant pituitary tumours, the reported prevalence in the background population is around 1:1000. The last two studies in the thesis focused on Cushing’s disease (CD), i.e. an ACTH-secreting pituitary tumour resulting in excess levels of cortisol. CD is associated with multiple comorbidities and increased mortality. The reversibility of comorbidities and mortality risk after remission of cortisol levels have been under debate. Study IV examined psychiatric consequences of CD, measured by the use of psychotropic drugs. 179 patients with CD and a quadrupled matched control group were followed from diagnosis and at 5- and 10-year follow-up. We found that use of antidepressants remained at around 25% of patients with CD, regardless of remission status, at diagnosis and follow-up, whereas drugs for somatic comorbidities decreased. Use of antidepressants, sleeping pills and anxiolytics was higher in patients with CD compared to controls at diagnosis and 5-year follow-up. A cross-sectional analysis of 76 patients in sustained biochemical remission for median 9.3 years showed that 25% were taking antidepressants, a significantly higher use than controls, OR 2.0 (95% CI 1.1-3.8). In addition, patients with CD had a higher use of psychotropic drugs, already in the 5-year period before diagnosis. Study V investigated mortality and causes of death in 371 patients with CD, compared to a quadrupled matched control group. Follow-up was median 10.6 years (IQR 5.7-18.2) after time of diagnosis. Overall mortality was increased in patients with CD, HR 2.1 (95% CI 1.5-2.8) and remained elevated for patients in remission at last follow-up (n=303), HR 1.5 (1.02-2.2). For patients not in remission (n=31), HR was 5.6 (2.7-11.6). Cardiovascular diseases (32/66) and infections (12/66) were overrepresented causes of death in patients with CD. Main conclusions of the thesis: Temozolomide improves outcome in patients with aggressive pituitary tumours/carcinomas and a low MGMT expression in the tumour predicts a favourable outcome. As additional therapies evolve, MGMT may help to tailor the treatment.Germline mutations in MMR genes may contribute to the development and clinical course of pituitary tumours and may be a novel cause of hereditary pituitary tumours.Patients with Cushing’s disease have a high use of psychotropic drugs that remains elevated despite achievement of biochemical remission, suggesting persisting negative effects on mental health and highlighting the need for long-term monitoring of psychiatric symptoms. In addition, psychiatric symptoms may be early and important signs of CD.Efforts to achieve biochemical remission are crucial to reduce mortality in CD. However, patients in remission still have an increased mortality compared to controls. This underscores the need for life-long monitoring and treatment of associated comorbidities in patients with CD.
Download or read book Pituitary Tumors written by Jürgen Honegger and published by Elsevier. This book was released on 2021-04-14 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Tumors: A Comprehensive and Interdisciplinary Approach provides the latest information on preclinical issues, diagnostic procedures, treatment options and post-treatment care for patients with pituitary tumors. The book includes basic and advanced knowledge for a broad audience, including physicians, endocrinologists, neurosurgeons, neuro-radiologists, neuro-ophthalmologists, neuro-pathologists, oncologists, radiotherapists and researchers who are investigating pituitary tumors. Readers will find the latest research surrounding progress on uncoding the molecular mechanisms involved in tumor genesis. In addition, standard treatment modalities, including surgery, medical treatment and radiosurgery are explored. Provides state-of-the-art knowledge from experts who cover all specialties involved in the field of pituitary tumors Offers a comprehensive presentation of related issues to pituitary tumors Delivers a complete reference book for a broad audience, providing both basic and advanced knowledge
Download or read book Pediatric Endocrinology written by Sally Radovick and published by Springer Science & Business Media. This book was released on 2013-02-20 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes new topics being seen more commonly in pediatric endocrinology practices related to obesity and type 2 diabetes mellitus and lipid disorders. Each chapter contains an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. Invaluable tables summarize the critical factors in etiology, clinical presentation, diagnosis, and therapeutic dosages. Pediatric Endocrinology: A Practical Clinical Guide, Second Edition, is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents.
