Download or read book Innovative Therapeutic and Immunomodulatory Strategies for Protozoan Infections written by Jorge Enrique Gomez-Marin and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book Innovative Therapeutic and Immunomodulatory Strategies for Protozoan Infections written by Jorge Enrique Gomez-Marin and published by Frontiers Media SA. This book was released on 2019-11-04 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human protozoan infections are an important target for development of new vaccines and drugs. No completely efficacious vaccines for human protozoan infections are available and in the case of malaria resistance to the most efficacious antimalarials has become a global challenge. In ocular toxoplasmosis complete eradication of the body is not possible, exposing patients to new reactivations. The need of treatment or vaccines for and of less toxic drugs for Leishmania are urgent tasks for protozoologists research community. New research strategies have appeared that enlarged the possibilities for treatment and vaccine development. Reverse vaccinology, bioinformatic search of second use drug candidates and ex vivo analysis have afforded new fields for development.
Download or read book Current Developments in the Detection and Control of Multi Drug Resistance written by Sanket Kaushik and published by Bentham Science Publishers. This book was released on 2022-07-26 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rise in the incidence of infections is caused by multi drugresistant (MDR) bacteria, it is essential to elucidate the basic mechanism ofantibiotic resistance to discover effective methods for diagnosis and treatmentof infections. The use of pathogen-specific probes offers a faster alternative forpathogen detection and could improve the diagnosis of infection. High resolutionmelting analysis techniques are useful for the detection of multi drugresistant pathogens. Rational Structural Based Drug Design is a common methodto identify a lead compound and take it forward for further developments.This book provides information about recent strategies involved in thediagnosis and treatment of infections caused by MDR bacteria. The volume coversthe use of molecular probes for the quantification of pathogenic bacteria, alongwith other techniques mentioned above. Chapters also cover the use of identificationof novel drug targets from the Lipid A biosynthesis and also from quorum sensingmediated biofilm formation in MDR bacteria. Chapters also cover herbal alternatives for the treatment of MDRbacteria like the use of Cassiaaungustifolia in treatment of various diseases. The reference is suitablefor biomedical students, cellular and molecular biologists.
Download or read book Immune evasion and defense strategies in parasitic protozoa host interactions written by Jian Du and published by Frontiers Media SA. This book was released on 2022-12-27 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recent Developments in Nanomaterial based Sensing of Human Pathogens written by Seshadri Reddy Ankireddy and published by Elsevier. This book was released on 2024-03-15 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Developments in Nanomaterial-Based Sensing of Human Pathogens gives insights into the alignment of recent developments in the field of nano-sensing of bacterial and viral pathogenic organisms. The book describes the role of biomarkers in the detection of fungal diseases and the importance of mycoplasmas in health and diseases that are naturally resistant to many common antibiotics, such as penicillin. Touching all areas of medical microbiology and analytical biochemistry, this book provides understanding to application-oriented microbial sensing concepts and updates knowledge with respect to recent advances on related aspects of pathogenic sensing. Presents in-depth coverage of nanosensors for a wide range of human pathogens Combines insights from nanotechnology, biology, and medicine for holistic pathogen detection Shows cutting-edge progress in analytics, biomarker detection, and innovative nanodevices for improved pathogen sensing Highlights clinical importance, serving as a valuable resource for pathogen detection and diagnostics
Download or read book Leishmaniases as Re emerging Diseases written by Farhat Afrin and published by BoD – Books on Demand. This book was released on 2018-10-10 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified.
Download or read book Phagocytes in Immunity Linking Material Internalization to Immune Responses and Therapeutic Strategies written by Johnathan Canton and published by Frontiers Media SA. This book was released on 2021-11-12 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Evolution in Pharmacology of Infectious Diseases 2022 written by Exequiel Oscar Jesus Porta and published by Frontiers Media SA. This book was released on 2024-03-21 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been tremendous advancements in the Pharmacology of Infectious Diseases in recent years. These recent advancements underline the importance of a multidisciplinary approach in the study of infectious diseases. In order to explore this fast-growing area, Frontiers is launching a new series of Research Topics focusing on the evolution of methods, processes, scientific breakthroughs and technology advances in the field of Pharmacology of Infectious Diseases. In this article collection, we seek contributions exploring the changing context, the recent advances, the challenges, and the emerging new perspectives within the field.
Download or read book Arthropod Venom Components and Their Potential Usage written by Katsuhiro Konno and published by MDPI. This book was released on 2020-03-25 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thousands of arthropod species, ranging from arachnids (spiders and scorpions) to hymenopterans (ants, bees, and wasps) and myriapods (centipedes), are venomous and use their venoms for both defense and predation. These venoms are invariably harmful to humans, and some may cause serious injuries, e.g., those from scorpions, spiders, and wasps. Arthropods’ venoms are also known as rich sources of biologically active compounds and have attracted the attention of toxin researchers for years. In this century, venom component analysis has progressed considerable due to the advances in analytical techniques, in particular, mass spectrometry and next-generation deep (DNA and RNA) sequencing. As such, proteomic and peptidomic analyses using LC–MS have enabled the full analysis of venom components, revealing a variety of novel peptide and protein toxins sequences and scaffolds, potentially useful as pharmacological research tools and for the development of highly selective peptide ligands and therapeutic leads, like chlorotoxin. Due to their specificity for numerous ion-channel subtypes, including voltage- and ligand-gated ion channels, arthropod neurotoxins have been investigated to dissect and treat neurodegenerative diseases and control epileptic syndromes. This Special Issue collects information on such progress, encouraging contributions on the chemical and biological characterization of venom components, not only peptides and proteins, but also small molecules, their mechanisms of action, and the development of venom-derived peptide leads.
Download or read book Immune Response Activation and Immunomodulation written by Rajeev Tyagi and published by BoD – Books on Demand. This book was released on 2019-04-17 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Response Activation and Immunomodulation has been written to address the perceived needs of both medical school and undergraduate curricula and to take advantage of new understandings in immunology. We have tried to achieve several goals and present the most important principles governing the function of the immune system. Our fundamental objective has been to synthesize the key concepts from the vast amount of experimental data that have emerged in the rapidly advancing field of immunology. The choice of what is most important is based on what is most clearly established by experimentation, what our students find puzzling, and what explains the wonderful efficiency and economy of the immune system. Inevitably, however, such a choice will have an element of bias, and our bias is toward emphasizing the cellular interactions in immune response by limiting the description of many of the underlying biochemical and molecular mechanisms to the essential facts. This book gives an insight into the role of cytokines in activating immune response during pathogenic invasion. Immunomodulation, aryl hydrocarbons, the role of the protein defensin and nucleated cells in provoking immune response, Bcl protein/gene-based apoptotic pathways, and plant-derived phytochemical-mediated immune response are all central themes of this book.
Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2002-07-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
Download or read book Immunopotentiation written by G. E. W. Wolstenholme and published by John Wiley & Sons. This book was released on 2009-09-16 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Download or read book Extracellular Vesicles in Infectious Diseases written by Shulamit Michaeli and published by Frontiers Media SA. This book was released on 2021-07-22 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Mechanisms of Parasite Invasion written by Barbara A. Burleigh and published by Springer Science & Business Media. This book was released on 2008-12-05 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.
Download or read book Veterinary Vaccines written by Samia Metwally and published by John Wiley & Sons. This book was released on 2021-04-01 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a concise and authoritative reference on the use of vaccines against diseases of livestock Compiled by Senior Animal Health Officers at The Food and Agriculture Organization of the United Nations, and with contributions from international leading experts, Veterinary Vaccines: Principles and Applications is a concise and authoritative reference featuring easily readable reviews of the latest research in vaccinology and vaccine immune response to pathogens of major economic impact to livestock. It covers advice and recommendations for vaccine production, quality control, and effective vaccination schemes including vaccine selection, specifications, vaccination programs, vaccine handling in the field, application, failures, and assessment of herd protection. In addition, the book presents discussions on the current status and potential future developments of vaccines and vaccination against selected transboundary animal diseases. Provides a clear and comprehensive guide on using veterinary vaccines to protect livestock from diseases Teaches the principles of vaccinology and vaccine immune response Highlights the vaccine production schemes and standards for quality control testing Offers easy-to-read reviews of the most current research on the subject Gives readers advice and recommendations on which vaccination schemes are most effective Discusses the today’s state of vaccines and vaccination against selected transboundary animal diseases as well as possible future developments in the field Veterinary Vaccines: Principles and Applications is an important resource for veterinary practitioners, animal health department officials, vaccine scientists, and veterinary students. It will also be of interest to professional associations and NGO active in livestock industry.
Download or read book Critical Needs and Gaps in Understanding Prevention Amelioration and Resolution of Lyme and Other Tick Borne Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.
Download or read book Novel Approaches to Colorectal Cancer written by and published by Academic Press. This book was released on 2021-06-18 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Approaches to Colorectal Cancer, Volume 151 in the Advances in Cancer Research series, is composed of 11 reviews covering state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. The book's chapters were written by recognized experts in the field, and include sections on molecular biomarkers in diagnosis and therapy, the interplay of diet, lifestyle, and the microbiome, early-age onset disease, mutational signature analysis, challenges in early detection, immunotherapy, organoid technology, the role of epigenetic alterations, disparities in minority populations, field carcinogenesis, and cancer as an evolutionary process. Each of these topics provides novel insights and concepts on various aspects of the nature of colorectal cancer, offering new opportunities for the management of a major source of cancer incidence and mortality. Provides information on the timely nature of the included topics, which represent the most current concepts and approaches in cancer research Offers outstanding and original reviews on colorectal cancer research Provides the authority and expertise of the authors, all of whom are highly recognized and conducting state-of-the-art investigations in cancer, with this release focusing on colorectal cancer
