Download or read book Innovative Concepts in Inflammatory Bowel Disease written by J. Emmrich and published by Springer Science & Business Media. This book was released on 1999-01-31 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic inflammatory bowel diseases represent an important medical problem, since they have a devastating impact on the quality of life and require longstanding medical care. Many medical disciplines are involved in tackling the immensely complex studies on pathogenesis, clinical expression and treatment possibilities. This book, the proceedings of the Falk Symposium 105 on `Innovative Concepts in Inflammatory Bowel Diseases', held in Rostock, Germany, on April 30 - May 2, 1998, brought together experts from different fields of science to allow a unified view on clinical and basic research. The main themes of the meeting were genetics, animal models, immunology, epithelial cells, endotoxin, diagnostic procedures, malignancy, medical therapies, and surgery. In each section of the book experts present state-of-the-art reviews with the very latest developments in the respective research areas followed by chapters on different aspects of inflammatory bowel diseases. They provide suggestions concerning future research and clinical management of patients with inflammatory bowel diseases.
Download or read book Innovative Concepts in Inflammatory Bowel Diseases written by Jörg Emmrich and published by . This book was released on 1998 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inflammatory Bowel Disease A Comprehensive Approach written by Remy Bowen and published by . This book was released on 2020-09-22 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammatory bowel disease (IBD) describes a set of conditions in which the intestines become inflamed. Ulcerative colitis and Crohn's disease are the two main types of IBD. The symptoms range from mild to severe and depend on the part of the intestinal tract involved. Abdominal cramps, diarrhea, iron deficiency anemia, weight loss, etc. are some common symptoms. In diagnosing IBD, it is imperative to first develop a differential diagnosis. Several conditions exhibit symptoms similar to Crohn's disease or colitis, such as irritable bowel syndrome, intestinal tuberculosis, Behçet's disease, nonsteroidal anti-inflammatory drug enteropathy, etc. No specific disease marker is yet known which enables a clear distinction between Crohn's disease and ulcerative colitis. Only through observation of the location and nature of the inflammation can a diagnosis be established. The management of IBD depends on the disease severity, type and extent. Immunosuppressive drugs, anti-inflammatory drugs, steroids and biological therapy for IBD are certain medical strategies for controlling the disease. Research is also being undertaken to explore the role of stem cell therapy in treating IBD. This book brings forth some of the most innovative concepts and elucidates the unexplored aspects of inflammatory bowel disease. It includes contributions of experts and scientists which will provide innovative insights into the diagnosis and management of IBD. It is a collective contribution of a renowned group of international experts.
Download or read book New Concepts in Inflammatory Bowel Disease written by Batool Mutar Mahdi and published by BoD – Books on Demand. This book was released on 2018-03-21 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammatory bowel disease is a chronic immune-mediated inflammation of the gastrointestinal tract of unknown origin, which includes Crohn's disease, ulcerative colitis, and inflammatory bowel disease of unclassified type. It is associated with different intestinal and extraintestinal manifestations like different neurological and psychiatric disorders. Histology is an important tool in the diagnosis and prognosis of inflammatory bowel disease and has an increasing part in patients' management. The objective of treatment is to make and keep long-lasting remission by immunosuppressive treatment like corticosteroids, thiopurines, and monoclonal antibodies directed against tumor necrosis factor alpha. Therapeutic drug monitoring of thiopurines by measuring levels of their metabolites has been proposed as a potentially effective tool in optimizing therapy in inflammatory bowel disease. Diets and their components influence microbiota of the intestine, function of the epithelial barrier, immune response, and other factors that have an important role in development and treatment of inflammation in the gut mucosa.
Download or read book Intestinal Inflammation Implications for Therapeutic Interventions in Ibd written by Daisy Ross and published by . This book was released on 2020-09-08 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammatory bowel disease refers to diseases which involve the chronic inflammation of the digestive tract. There are primarily two types of inflammatory bowel diseases, namely, ulcerative colitis and Crohn's disease. Ulcerative colitis involves long-lasting inflammation in the innermost lining of the large intestine. Crohn's disease is characterized by the inflammation of the lining of the digestive tract. Some of the symptoms which accompany these diseases are severe diarrhea, weight loss, fatigue and abdominal pain. It is caused by immune malfunction. An abnormal immune response can lead to the immune system attacking the cells in the digestive tract. This book contains some path-breaking studies in the field of inflammatory bowel disease. It elucidates the concepts and innovative models around therapeutic interventions with respect to this disease. This book is appropriate for students seeking detailed information in this area as well as for experts.
Download or read book Immunoregulation in Inflammatory Bowel Diseases Current Understanding and Innovation written by A. Dignass and published by Springer. This book was released on 2007-02-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the proceedings of the Falk Symposium 153 on Immunoregulation in Inflammatory Bowel Diseases – Current Understanding and Innovation, held May 2006 in Berlin, Germany. It critically discusses established and emerging new concepts in the diagnosis and treatment of IBD, reflecting the recent advancements in the aetiopathogenesis of these diseases.
Download or read book Advances in Inflammatory Bowel Diseases written by P. Rutgeerts and published by Springer Science & Business Media. This book was released on 1998-12-31 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ulcerative colitis and Crohn's disease remain a great therapeutic challenge to the medical community. In recent years knowledge about the pathogenesis of these diseases has progressed rapidly but the cause of the diseases remains completely unknown. It has become clear that dysregulation of the mucosal immune system is the basis for the chronic evolution of the diseases in a genetically susceptible population. Exciting new therapeutic approaches have been attempted in the last couple of years and cytokine and anti-cytokine treatments in particular seem very promising, especially in intractable disease. The format of the Falk Symposium 106 on `Advances in Inflammatory Bowel Diseases', held in Brussels, Belgium, June 18-20, 1998, was somewhat innovative as each session attempted to link the new insights into pathogenetic mechanisms with new therapeutic approaches, resulting in optimal information transfer. The classic therapeutic schemes were updated with a special focus on step-wise build-up of therapy.
Download or read book Origins and Directions of Inflammatory Bowel Disease written by Joseph B. Kirsner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few human illnesses today are so challenging, medically, scientifically, and socio-economically, as the "nonspecific" inflammatory bowel diseases (IBD): ulcerative colitis and Crohn's disease. Originating several centuries ago but essentially diseases of the 20th century, often attacking children and young adults, involving all bodily systems as well as the gastrointestinal tract, ulcerative colitis and Crohn's disease have emerged in recent decades as among the more "glamorous" unsolved diseases, presenting unusual opportunities for insightful clinical and investigative study. Many of the prevailing concepts originated during the early and mid 20th century. The purpose of Origins and Directions of Inflammatory Bowel Disease is to review these earlier studies and their evolution "from the mystical to the molecular," and guide investigators and physicians through the challenging clinical and scientific maze of IBD.
Download or read book Inflammatory Bowel Disease written by Stephan R. Targan and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 1429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the state-of–the-art book on inflammatory bowel disease you have been waiting for Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD. In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine. This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library.
Download or read book Inflammatory Bowel Disease written by M. Campieri and published by Springer Science & Business Media. This book was released on 2002-03-31 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the proceedings of the Falk Symposium No. 122 on "Inflammatory Bowel Disease - A Clinical Case Approach to Pathophysiology, Diagnosis, and Treatment", held in Bologna, Italy, on June 22-23, 2001, and deals with some major issues concerning Genetics of IBD, Pediatrics in IBD, Early vs Late IBD, Bacteria and Gut Inflammation, Refractory CD, Fistulizing CD, Refractory Distal Colitis, and Complications of Ileal-Pouch Anastomosis. The main aim of the meeting was to highlight the value of an integrated clinical approach and the importance of clinical research in developing innovative methods of treatment.
Download or read book Gastrointestinal Inflammation and Disturbed Gut Function The Challenge of New Concepts written by G. Holtmann and published by Springer Science & Business Media. This book was released on 2003-09-30 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, the proceedings of Falk Symposium 130 on 'Gastrointestinal Inflammation and Disturbed Gut Function: The Challenge of New Concepts', held in Freiburg, Germany, on October 4-6, 2002 (Part I of the Gastroenterology Week Freiburg 2002), reviews ground-breaking work and will stimulate new research in the functional GI disorders, from the bench to the bedside. Basic scientists, clinical researchers and clinicians interested in this field explore controversial and exciting areas of research, and consider targets for future therapeutic interventions.
Download or read book Immunosuppression in Inflammatory Bowel Diseases written by K. Fellermann and published by Springer Science & Business Media. This book was released on 2001-06-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aetiology of the chronic inflammatory bowel diseases - Crohn's disease and ulcerative colitis - is still enigmatic. The therapeutic approach has therefore traditionally focused on anti-inflammatory principles, including corticosteroids and aminosalicylates. Since a significant proportion of patients is steroid-dependent or refractory and because of the problematic side-effects of long-term systemic steroids, active immunosuppression has gained acceptance in the field. The classical immunosuppressants azathioprine and 6-mercaptopurine have long been evidence-based in IBD, but underused. Recently, methotrexate and cyclosporine have also been proven to be effective in certain situations. Newer drugs like tacrolimus, mycophenolate and others may be similarly useful but their potential is still unclear. Finally, the immune modifiers including IL-10 and TNF-antibodies have been successfully subjected to controlled trials. Other experimental drugs discussed in this book are on the horizon. This volume is the Proceedings of Falk Symposium 119 held in Freiburg-im-Breisgau, Germany, October 3-4, 2000, and covers systematically the field of immunosuppression in inflammatory bowel diseases. It is hoped that it will further the prudent use of these drugs in the proper clinical situations by increasing our understanding of both the mechanisms of action and the clinical benefit to the patient.
Download or read book Inflammatory Bowel Disease written by Ramona Rajapakse and published by Springer Nature. This book was released on 2021-09-23 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book uses new thinking on precision medicine and the interplay of genetic factors, the microbiome, and external triggers to build on the core concepts of inflammatory bowel disease. It outlines the latest findings in targeting therapies to the individual patient with Crohn’s and colitis, management of chronic infections in the setting of immunomodulators and biologics, non-surgical therapy of dysplasia in colitis patients, and redefining and structuring the problematic pouch. In addition, this book features useful chapters dedicated to the economic aspects of IBD in an increasingly constrained healthcare system, as well as the patient experience and the role of subspecialist telemedicine care. Written by specialists and thought leaders in the field, Inflammatory Bowel Disease: Pathogenesis, Diagnosis and Management provides a concise but highly relevant account of the latest thinking and concepts in IBD.
Download or read book VI International Symposium on Inflammatory Bowel Diseases written by D. Rachmilewitz and published by Springer Science & Business Media. This book was released on 2002-06-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, the proceedings of Falk Symposium No. 123, VI International Symposium on Inflammatory Bowel Diseases, held in Istanbul, Turkey, on September 3-5, 2001, focuses on the issues and controversies pertinent to IBD in the 21st century. The achievements in medical, surgical, and in the basic sciences in the last twenty years since the first Jerusalem IBD Symposium are summarized in detail. Controversies with respect to the medical treatment of inflammatory bowel diseases are discussed. One section deals with surgical issues such as laparoscopic surgery in inflammatory bowel diseases, ileo-anal pouches and the surgical treatment of Crohn's disease. The last section is devoted to the biological treatment of IBD and to the needs both in medical science and in the clinic.
Download or read book Inflammatory Bowel Disease Translation from Basic Research to Clinical Practice written by B. Vucelic and published by Springer Science & Business Media. This book was released on 2004-12-09 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: The amount of information on the pathogenesis of inflammatory bowel disease is growing rapidly. This is reflected by a continuous increase in the number of papers presented at international GI meetings. To make things more difficult for practicing physicians, there is also a large number of new clinical trials being published which require periodical critical reviews and recommendations. Faced with these issues, the scientific commitee of the Falk Symposium No. 140 decided to take a different approach and to apply a novel format that is reflected in the title of the Symposium: "Translation from basic research to clinical practice". This book contains the proceedings of that Symposium, held in Dubrovnik, Croatia, on May 7–8, 2004. The sections are designed so that they start with the information from basic sciences on different aspects of these complex diseases and further lead to their clinical implications. Special attention is paid to the mechanisms of actions of established drugs. The last two sections are clinically oriented and focus on the most difficult aspects of both Crohn's disease and ulcerative colitis. This format provides state-of-the-art chapters by leading experts in the field and at the same time up-to-date information on the clinical application of the new knowledge.
Download or read book New Concepts in Inflammatory Bowel Disease written by Batool Mutar Mahdi and published by . This book was released on 2018 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammatory bowel disease is a chronic immune-mediated inflammation of the gastrointestinal tract of unknown origin, which includes Crohn's disease, ulcerative colitis, and inflammatory bowel disease of unclassified type. It is associated with different intestinal and extraintestinal manifestations like different neurological and psychiatric disorders. Histology is an important tool in the diagnosis and prognosis of inflammatory bowel disease and has an increasing part in patients' management. The objective of treatment is to make and keep long-lasting remission by immunosuppressive treatment like corticosteroids, thiopurines, and monoclonal antibodies directed against tumor necrosis factor alpha. Therapeutic drug monitoring of thiopurines by measuring levels of their metabolites has been proposed as a potentially effective tool in optimizing therapy in inflammatory bowel disease. Diets and their components influence microbiota of the intestine, function of the epithelial barrier, immune response, and other factors that have an important role in development and treatment of inflammation in the gut mucosa.
Download or read book Malignant Liver Tumours Basic Concepts and Clinical Management written by F. Berr and published by Springer Science & Business Media. This book was released on 2002-11-30 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC), both increasing in incidence, have become a major topic of basic and clinical research as well as clinical practice in hepatology. Experts in the field update the current concepts on the carcinogenesis of HCC and CC such as genetic alterations in the pathways of cell cylce and apoptosis regulation, the hypothesis of dedifferentiation of hepatocytes to the malignant phenotype vs that of activation of hepatic progenitor cells incapable of maturation (maturation arrest hypothesis). In spite of an increasing number of genetic alterations described in human HCC as well as cell regulatory pathways tested in experimental HCC models, the key hits causing progression of the cell cycle in imbalance with apoptosis, tissue invasive growth and metastatic potential of cell clones still remain elusive. Very powerful genomic and proteomic techniques are promising insights into the carcinogenesis of liver malignancies that will allow more efficient therapeutic strategies. The current concepts on risk profiling, surveillance of risk groups and therapeutic strategies are evidence-based for HCC and less detailed for CC. Surveillance of risk groups improves detection of liver tumours in curable stages. Best strategies for curative treatment of HCC use neoadjuvant antitumour therapies before liver transplantation and a role is emerging for living donor-related liver transplantation. New palliative therapies for HCC are in the experimental stage with biological response modifiers, including angiogenesis inhibitors, and entering phase II clinical trials with the alpha-fetoprotein derived vaccines.
