Download or read book Inflammation in the Pathogenesis of Chronic Diseases written by Randall E. Harris and published by Springer Science & Business Media. This book was released on 2007-05-09 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, a worldwide panel of leading experts discuss the role of inflammation in the pathogenesis of major chronic diseases and the current controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors. The authors provide exciting and enlightening perspectives on COX-2 and related molecular targets in the future of medicine, including historical perspectives.
Download or read book Inflammation Lifestyle and Chronic Diseases written by Bharat B. Aggarwal and published by CRC Press. This book was released on 2016-04-19 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress and inflammation are among the most important factors of disease. Chronic infections, obesity, alcohol and tobacco usage, radiation, environmental pollutants, and high-calorie diets have been recognized as major risk factors for a variety of chronic diseases from cancer to metabolic diseases. All these risk factors are linked to ch
Download or read book Chronic Inflammation written by Sashwati Roy and published by CRC Press. This book was released on 2012-09-17 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation
Download or read book Regulation of Inflammation in Chronic Disease written by Jixin Zhong and published by Frontiers Media SA. This book was released on 2019-07-19 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book The Physiology of Inflammation The Final Common Pathway to Disease written by Alexandrina Ferreira Mendes and published by Frontiers Media SA. This book was released on 2019-02-20 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic diseases are increasingly recognized as involving low grade inflammation, that is, a self-perpetuating tissue response to stress caused by exogenous or endogenous triggers, that progressively evokes danger-associated molecular pattern release, ultimately driving tissue damage and loss of function. This response is frequently unapparent clinically, thus the designation "low grade". This eBook comprises nineteen reviews and original articles that provide the most updated knowledge on the causes and roles of this inflammatory response in a variety of diseases and conditions. The editorial that precedes these articles not only summarizes each one, but provides a broader interpretation of the role of inflammation in health and a variety of disease conditions, the underlying mechanisms and the targets more promising for therapy. Finally, it also highlights the most relevant and emerging research topics that are already shaping future directions for the development of more fine-tuned and innovative therapies.
Download or read book The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae written by Rainer Straub and published by Academic Press. This book was released on 2015-04-08 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, long-term application of this program leads to typical disease sequelae such as fatigue / depressive symptoms, sleep disturbances, anorexia, malnutrition, muscle wasting – cachexia, cachectic obesity, insulin resistance, dyslipidemia, alterations of steroid hormone axes, disturbances of the hypothalamic-pituitary-gonadal axis, elevated sympathetic tone, hypertension, volume expansion, decreased parasympathetic tone, inflammation–related anemia, bone loss, hypercoagulability, circadian rhythms of symptoms, and disease exacerbation by stress . The Origin of Chronic Inflammatory Systemic Diseases and Their Sequelae demonstrates concepts of neuroendocrine immunology, energy and water regulation, and evolutionary medicine in order to show that the uniform response that regulates systemic energy and water provision, has been positively selected for acute physiological responses and short-lived disease states, but is a misguided program in chronic inflammatory diseases and aging. Offers a broad conceptual framework with a strong clinical link, written in an easy to grasp style and demonstrating the link to aging research Describes the important principles derived from basic immunology that are used to explain pathogenesis of chronic inflammatory systemic diseases with a focus on autoimmunity Defines the bioenergetics and energy regulation of the body explaining common response pathways typical for systemic inflammation Makes use of evolutionary medicine theory to demonstrate the uniformity of the systemic response Explains the appearance of typical disease sequelae on the basis of the three pillars: neuroendocrine immunology, energy regulation, and evolutionary medicine theory Contains color figures and tables that explain the field to newcomers
Download or read book Translational Inflammation written by and published by Academic Press. This book was released on 2018-11-24 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Inflammation links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming a valuable tool in both direct treatment and the development of therapeutics. Translational Inflammation, the 4th volume in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. Emphasizes the role of inflammation in disease and therapeutic approaches Integrates broad concepts relating inflammation to other fields Offers a bridge to review literature and primary research on the inflammatory response towards medical application
Download or read book Hyperuricemic Syndromes written by Claudio Ronco and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uric acid disorders are involved in both nephrological and hematological diseases. One of these crystal-associated diseases which has been known since antiquity is gout. More recently, tumor Lysis syndromes have been identified which affect patients with cancer, especially in the phase of cellular destruction after chemotherapy. The detection of these hyperuricemic syndromes, together with the improved understanding of urate handling by the kidney, have spurred new interest in the pathophysiology of hyperuricemic states, their clinical consequences and management. Moreover, the recent development of a recombinant form of urate oxidase transforming uric acid into allantoin (Rasburicase) has caused new interest in the pathophysiology of hyperuricemia and the potential applications of this new drug. The multidisciplinary approach of this book offers new insights into the metabolic syndromes in question by uniting authors from the fields of biochemistry, pharmacology, rheumatology, onco-hematology, and nephrology. The result is a compendium of the present knowledge in the field, which will also be very useful as a reference tool for professionals and students who want to expand their knowledge on this topic.
Download or read book Chronic Inflammation written by Sashwati Roy and published by CRC Press. This book was released on 2016-10 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions provides an exposition of the process of chronic inflammation in three parts: Systems Biology of Inflammation and Regulatory Mechanisms describes the process of chronic inflammation including initiation, progression, and resolution. Pathologies Associated with Inflammation gives a rigorous and critical treatment of specific human health disorders where chronic inflammation plays a major role. Nutrition & Therapeutics for Inflammatory Diseases details the protective abilities of structurally diverse antioxidants, phytochemicals, anti-inflammatory diets, omega-3 fatty acids, NSAIDs, disease modifying anti-rheumatic drugs, and novel regimens. Designed for scientists as well as clinicians, Chronic Inflammation provides critical understanding of the key checkpoints that regulate chronic inflammation. Going beyond the epidemiology of chronic inflammation, the text covers regulatory mechanisms controlling inflammation initiation, progression, and resolution. The authors address pathologies associated with inflammation and provide various nutritional and therapeutic interventions for inflammatory diseases.
Download or read book Oxidative Stress and Inflammation in Non communicable Diseases Molecular Mechanisms and Perspectives in Therapeutics written by Jordi Camps and published by Springer. This book was released on 2014-07-19 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress and inflammation underpin most diseases; their mechanisms are inextricably linked. For example, chronic inflammation is associated with oxidation, anti-inflammatory cascades are linked to decreased oxidation, increased oxidative stress triggers inflammation and redox balance inhibits the inflammatory cellular response. Whether or not oxidative stress and inflammation represent the causes or the consequences of cellular pathology, they contribute significantly to the pathogenesis of non-communicable diseases. The incidence of obesity and other related metabolic disturbances are rising, as are age-related diseases due to progressively aging populations. Interrelations between the mechanisms of oxidative stress and of inflammatory signaling and metabolism are, in the broad sense of energy transformation, being increasingly recognized as part of the problem in non-communicable diseases. The book Oxidative Stress and Inflammation in Non-communicable Diseases: Molecular Mechanisms and Perspectives in Therapeutics is an update on the latest research on the molecular basis of non-communicable diseases and the search for possible therapeutic alternatives. The authors of this monograph are experts in their field and the book as a whole, provides an overview of the biochemical alterations underlying diseases such as cardiovascular disease, cancer, obesity, renal disease, neurological diseases and diabetes, emphasizing those aspects that they share in common. We hope that this book will be useful for researchers in biomedicine and also for physicians interested in finding the root causes of the disease, as well as for post-graduate students in biochemistry, molecular biology, nutrition or medicine.
Download or read book Inflammation Chronic Diseases and Cancer written by Mahin Khatami and published by BoD – Books on Demand. This book was released on 2012-03-09 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of excellent reviews and perspectives contributed by experts in the multidisciplinary field of basic science, clinical studies and treatment options for a wide range of acute and chronic inflammatory diseases or cancer. The goal has been to demonstrate that persistent or chronic (unresolved or subclinical) inflammation is a common denominator in the genesis, progression and manifestation of many illnesses and/or cancers, particularly during the aging process. Understanding the fundamental basis of shared and interrelated immunological features of unresolved inflammation in initiation and progression of chronic diseases or cancer are expected to hold real promises when the designs of cost-effective strategies are considered for diagnosis, prevention or treatment of a number of age-associated illnesses such as autoimmune and neurodegenerative diseases as well as many cancers.
Download or read book Reprogramming Stromal Cells in Chronic Inflammation and Cancer written by Ioannis S. Pateras and published by Frontiers Media SA. This book was released on 2022-01-05 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Impact of Nutrition and Statins on Cardiovascular Diseases written by Ioannis Zabetakis and published by Academic Press. This book was released on 2019-01-15 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Impact of Nutrition and Statins on Cardiovascular Diseases presents a summary of the background information and published research on the role of food in inhibiting the development of cardiovascular diseases. Written from a food science, food chemistry, and food biochemistry perspective, the book provides insights on the origin of cardiovascular diseases, an analysis of statin therapy, their side effects, and the role of dietary intervention as an alternative solution to preventing cardiovascular diseases. It focuses on the efficacy of nutrition and statins to address inflammation and inhibit the onset of disease, while also providing nutrition information and suggested dietary interventions. Includes a bioscience approach that focuses on inflammation and revisits the lipid hypothesis Presents the view that nutritional interventions have considerable value, not only for reducing cardiovascular risk for CVDs patients, but also acting as the best precaution for otherwise healthy people Advocates that nutritional habits that are formed at a young age are the best way to tackle the global epidemic that is CVDs
Download or read book Oxidative Damage to Nucleic Acids written by Mark D. Evans and published by Springer Science & Business Media. This book was released on 2009-06-11 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides up-to-date coverage of selected topics in nucleic acid oxidation. The topics have been selected to cover everything from basic chemical mechanisms, repair of damage and the biological and pathological meaning of DNA oxidation. The chapters are authored by leading, research active, international experts in the respective topics.
Download or read book Neutrophilic Inflammation and Diseases Pathophysiology Biomarkers and Therapeutic Targets written by Dario C. Ramirez and published by . This book was released on 2020-07-25 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Metabolic Ghetto written by Jonathan C. K. Wells and published by Cambridge University Press. This book was released on 2016-07-21 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: A multidisciplinary analysis of the role of nutrition in generating hierarchical societies and cultivating a global epidemic of chronic diseases.
Download or read book Inflammation Natural Resources and Its Applications written by Parag Jain and published by Springer. This book was released on 2014-12-04 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation is the very natural process of our body; it does its work immediately and smoothly along with lots of helpers. Inflammation is linked to immune system as acute inflammatory or pro-inflammatory phase through macrophage activation. This book is for researchers and scholars in the field of life sciences and medical sciences. The book contains all inflammatory sources around the world. It emphasizes on anti-inflammatory sources along with its active inflammatory constituents and other medicinal uses with authentic references. Anti-inflammation is a kind of activity with is found in nearly all of the natural sources used for major biological activities. So, the book helps them to correlate their activity of interest with anti-inflammatory source. The present work deals with illustrative representation of inflammation, causes of inflammation, inflammatory mediators, anti-inflammatory sources other uses and inflammation and lifestyle. It mainly provides the researchers the updated information from the ancient to the most recent ongoing research on inflammation. This book imparts pace to their idea of thinking, assist to make clear predictions before proceeding to research. The introduction includes natural sources of inflammation and its benefits; the sources are from plant, animal and marine. The book tells how these sources are useful for us to cure several diseases and opens new path for further research. Inflammation part of the book is well presented along with its phases, types and other diseases interrelated with inflammation. Inflammatory mediators, the foremost player of inflammation are defined in a very pleasant and convenient manner. The chapter includes both cell- derived and plasma - derived mediators illustratively with their synthesis and action. Natural source of anti-inflammation is the heart chapter of this book which contains all anti-inflammation sources from plants, marine and animals. This chapter also contains short description of most of the sources, its availability and uses. The authors have also added inflammatory models for assessment of biological activities of natural sources both in vitro and in vivo. Inflammation free lifestyle is described very nicely in the book. The contents are very specific and relevant to its topic; all the data provided is unique and useful. The anti-inflammatory table includes sources, plant parts used, active constituents and other uses. This data provides ample information regarding anti-inflammatory research and innovation. The highlights of this book shall be: -Describes almost all anti-inflammatory sources around the globe at one place in a more convenient tabulated form -Illustrative representation makes the book more attractive and interactive
