Download or read book Induction of Bone Resorbing Agents by Titanium Particulates written by TT. Glant and published by . This book was released on 1996 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although titanium and titanium alloys demonstrate excellent biocompatability in bulk form, titanium in particulate form can provoke a variety of cellular responses. In this series of experiments, we have shown that commercially pure titanium particulates of phagocytosable size stimulate the secretion of mediators of bone resorption (prostaglandin E2 and interleukin-1) from macrophages and cause bone resorption in organ culture. In addition, we have shown that phagocytosable titanium particles stimulate fibroblasts to up regulate the expression of matrix metalloproteinases (stromelysin and collagenase) without a substantial effect on the tissue inhibitor of these enzymes (TIMP). Titanium particulates also have a suppressive effect on procollagen synthesis by an osteoblast-like cell line. Thus, titanium particulates have the capacity to stimulate bone resorption and inhibit bone matrix formation.

Download or read book Medical Applications of Titanium and Its Alloys written by Jack E. Lemons and published by ASTM International. This book was released on 1996 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty papers presented at a 1994 symposium cover the basic materials science issues regarding the processing of titanium alloys, and the controversy regarding their use in medicine. Coverage includes orthopaedic, dental, and cardiovascular applications, with a primary focus on the orthopaedic. Info

Download or read book Materials and Coatings for Medical Devices written by and published by ASM International. This book was released on 2009-01-01 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Materials Information Society, MPMD-Materials and Processes for Medical Devices."

Download or read book Biomechanics and Biomaterials in Orthopedics written by Dominique G. Poitout and published by Springer. This book was released on 2016-06-15 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the constant evolution of implant technology, and improvement in the production of allograft and bone substitutes, the armamentarium of the orthopaedic surgeon has significantly expanded. In particular, the recent involvement of nanotechnologies opens up the possibilities of new approaches in the interactive interfaces of implants. With many important developments occurring since the first edition of this well-received book, this updated resource informs orthopaedic practitioners on a wide range of biomechanical advances in one complete reference guide. Biomechanics and Biomaterials in Orthopedics, 2nd edition compiles the most prominent work in the discipline to offer newly-qualified orthopedic surgeons a summary of the fundamental skills that they will need to apply in their day-to-day work, while also updating the knowledge of experienced surgeons. This book covers both basic concepts concerning biomaterials and biomechanics as well as their clinical application and the experience from everyday practical use. This book will be of great value to specialists in orthopedics and traumatology, while also providing an important basis for graduate and postgraduate learning.

Download or read book Surgery of the Hip E Book written by Daniel J. Berry and published by Elsevier Health Sciences. This book was released on 2019-09-24 with total page 1344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering authoritative, comprehensive coverage of hip surgery, the 2nd Edition of Surgery of the Hip is the definitive guide to hip replacement, other open and arthroscopic surgical procedures, and surgical and nonsurgical management of the hip across the lifespan. Modeled after Insall & Scott Surgery of the Knee, it keeps you fully up to date with the latest research, techniques, tools, and implants, enabling you to offer both adults and children the best possible outcomes. Detailed guidance from expert surgeons assists you with your toughest clinical challenges, including total hip arthroplasty, pediatric hip surgery, trauma, and hip tumor surgery. Discusses new topics such as direct anterior approach for total hip arthroplasty, hip pain in the young adult, and hip preservation surgery. Contains new coverage of minimally invasive procedures, bearing surface selection, management of complications associated with metal and metal bearing surfaces, management of bone loss associated with revision THA, and more. Provides expert, personal advice in "Author’s Preferred Technique" sections. Helps you make optimal use of the latest imaging techniques, surgical procedures, equipment, and implants available. Covers tumors of the hip, hip instability and displacement in infants and young children, traumatic injuries, degenerative joint disorders, and rehabilitation considerations—all from both a basic science and practical clinical perspective.

Download or read book Handbook Of Biomaterials Evaluation written by Andreas F von Recum and published by CRC Press. This book was released on 1998-12-18 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook addresses the needs of those who are involved in inventing, developing, and testing implants and are concerned about the interactions between biomaterial and body tissue. The authors explore the physical, chemical, mechanical and regulatory considerations of synthetic materials used in surgical and implant procedures, and how these factors impact the latest developments and new approaches. This updated edition provides the biomaterials professional with necessary information on a range of issues, including bulk characterization, surface evaluations, toxicological evaluations, in vitro methods for safety evaluation, methods for evaluating materials in special applications, surgical considerations, systems implantology, soft and hard tissue history, regulatory aspects, and clinical trials.

Download or read book Joint Arthroplasty written by Shinichi Imura and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The introduction of total joint arthroplasty throughout the world has contributed manifold benefits to patients who suffer from joint diseases. Concurrently, however, there has been an increase in revision surgery. Many orthopedic surgeons agree that durability of prostheses is an eternal problem. In particular, periprosthetic osteolysis recently has been identified as one of the serious problems affecting prosthetic dura bility. To improve durability, osteolysis and many other problems must be investi gated and solved both experimentally and clinically with respect to such aspects as prosthetic material, design, and biological and biomechanical behavior. This book comprises 37 papers that were presented by orthopedic surgeons and biomedical engineers at the 28th Annual Meeting of the Japanese Society for Replace ment Arthroplasty, held in March 1998 in Kanazawa, Japan. The volume is thus a compilation of the latest knowledge about the pathogenesis and reduction of osteolysis and wear, newly developed total hip prostheses, and other current topics of total knee arthroplasty. We earnestly hope that this book will be of benefit to clinicians and researchers, and that it will contribute to the creation of more durable total joint prostheses in the future. SHINICHI IMURA v Contents Preface .................... '" .. .. .. ... . .. .. .. . ... .. . . .. . ... . . .. . V List of Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XI . . . . . . . . . . . . Part 1 Wear and Pathogenesis of Osteolysis Friction and Wear of Artificial Joints: A Historical Review N. AKAMATSU ................................................ , 3 Matrix Degradation in Osteoclastic Bone Resorption Under Pathological Conditions .

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1996 with total page 1340 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nano and Microparticle Induced Cell Death Inflammation and Immune Responses written by Shrikant R. Mulay and published by Frontiers Media SA. This book was released on 2019-07-19 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nano- and microparticles including crystals, synthetic biomaterials, misfolded proteins or environmental particulates are involved in a wide range of biological processes and diseases. They may present as intrinsic or environmental toxins but may also be applied intentionally, e.g. as immune adjuvants, drug carriers or ion exchangers. The discovery that a wide range of nano- and microparticles share the capacity to induce IL-1β secretion via activation of the NLRP3 inflammasome in dendritic cells and macrophages has led to the hypothesis that nano- and microparticles may contribute in a uniform mechanistic manner to different disease entities. Other molecular mechanisms triggered by a range nano- and microparticles have also recently been identified including (i) the induction of regulated necrosis; (ii) neutrophil extracellular trap (NET) formation and (iii) foreign body granuloma formation as a mechanism of persistent tissue inflammation and scarring. Research on the biology of nano- and microparticle handling is currently under intense investigation. The cell type-specific responses of nano- and microparticle exposure deserves careful attention as well as the related secondary responses to these particles that lead to tissue remodeling. The immune system is at the center of these processes in terms of particle clearance, particle-induced cell death and inflammation, thereby limiting particle-related inflammation and orchestrating wound healing responses. In this Research Topic, we welcomed the submission of Original Research, Review and Mini-Review articles that addressed the significance of the immune system in particle-induced cell death, inflammation and immune responses. These findings will help facilitate new approaches to the prevention and management of particle-related diseases.

Download or read book Nanotechnology for the Regeneration of Hard and Soft Tissues written by Thomas J. Webster and published by World Scientific. This book was released on 2007 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: The future growth and development of Asia - the most dynamic economic region in the world today - will have important implications for the rest of the global economy. This book offers a futuristic perspective of a wide array of developmental challenges and opportunities facing Asian economies over the next two decades. The future is approached from several different developmental paradigms including technological change and innovation, regional cooperation within Asia and between Asia and the West, poverty reduction, ethics and corruption, and environmental challenges. Future prospects for the two giant economies of China and India are also explored. By offering a comprehensive look at the medium-term future of Asia from such a wide range of different viewpoints, this fascinating book will interest economists, social scientists, politicians, international investment managers and the general public alike.

Download or read book Revision Total Knee Arthroplasty written by Jonathan P. Garino and published by Lippincott Raven. This book was released on 1998 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leading experts in total knee arthroplasty, this volume is a technique-oriented "how-to" guide to revision of failed arthroplasties. The book is sharply focused on the practical skills the surgeon needs to evaluate a failed knee replacement and safely and successfully reconstruct the joint. The authors describe all current reconstructive techniques and prosthetic options and offer advice on preventing and managing complications. More than 500 illustrations, including 188 full-color photographs, complement the text.

Download or read book Biomedical Materials drug Delivery Implants and Tissue Engineering written by Thomas Neenan and published by . This book was released on 1999 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2004 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 2003 with total page 2316 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book COTF BIO BND Clinical Orthopaedics and Related Research written by and published by . This book was released on 1990 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Bone Research Protocols written by Miep H. Helfrich and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last decade has seen a tremendous advance in our understanding of bone biology. The genes responsible for the majority of rare inherited bone disorders have been identified and much progress has been made in the identification of genes in polygenic disorders such as Paget’s disease and complex multigene diseases such as osteoporosis. Transgenic technology has identified further genes, sometimes unexpectedly, with profound effects on bone. This wealth of new genetic information will undoubtedly lead to extensive cell biological studies to understand the mechanisms by which these gene products affect bone mass and bone strength. In Bone Research Protocols a catalogue of protocols has been assembled to perform such mechanistic studies. In the tradition of the Methods in Molecular Medicine series, the chapters are practical laboratory protocols that should enable the reader to carry out the techniques from scratch. To our knowledge this is the first time such a truly practical manual on well-established bone methods has been assembled, and this volume aims to be complementary to and follow on from the more theoretical Methods in Bone Biology, edited by Arnett and Henderson (1).

Download or read book Journal of the Royal Society Interface written by and published by . This book was released on 2005 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Transactions of the Annual Meeting of the Orthopaedic Research Society written by Orthopaedic Research Society. Meeting and published by . This book was released on 2002 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consists of the transactions of the 22nd- annual meeting of the society.