Download or read book Inducible Gene Expression Hormonal signals written by Patrick Alexander Baeuerle and published by . This book was released on 1995 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inducible Gene Expression Volume 1 written by P.A. Baeuerle and published by Birkhäuser. This book was released on 1994-12-22 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells have evolved multiple strategies to adapt the composition and quality of their protein equipment to needs imposed by changes in intra- and extracellular conditions. The appearance of pro teins transmit ting novel functional properties to cells can be controlled at a transcrip tional, posttranscriptional, translational or posttranslational level. Extensive research over the past 15 years has shown that transcriptional regulation is used as the predominant strategy to control the production of new proteins in response to extracellular stimuli. At the level of gene transcription, the initiation ofmRNA synthesis is used most frequently to govern gene expression. The key elements controlling transcription initiation in eukaryotes are activator proteins (transactivators) that bind in a sequence-specific manner to short DNA sequences in the of genes. The activator binding sites are elements of larger proximity control units, ca lied promoters and enhancers, which bind many distinct proteins. These may synergize or negatively cooperate with the activators. The do novo binding of an activator to DNA or, if already bound to DNA, its functional activation is what ultimately turns on a high-level expression of genes. The activity of transactivators is controlled by signalling pathways and, in some cases, transactivators actively partici pate in signal transduction by moving from the cytoplasm into the nuc1eus. In this first volume of Inducible Gene Expression, leading scientists in the field review six eukaryotic transactivators that allow cells to respond to various extracellular stimuli by the expression of new proteins.
Download or read book Inducible Gene Expression Volume 2 written by P.A. Baeuerle and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of two volumes which aim to cover all established eukaryotic transcription factor systems that are direct targets for the signal transduction pathways. Leading molecular biologists contribute reviews on topics which take a broad view, and which should be of interest to students and advanced researchers in biology and medicine. Chapters attempt to answer such fundamental questions as: what is the signal and how and when is it produced? What is the receptor, and what further signalling molecules are involved? What is the biochemistry and molecular biology of the transcription factor that is the ultimate target of the signalling pathway? What is the physiological role of factor?
Download or read book Inducible Gene Expression written by P.A. Baeuerle and published by Birkhäuser. This book was released on 1994-12-22 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inducible Gene Expression Volume 2 written by P.A. Baeuerle and published by Progress in Gene Expression. This book was released on 1995 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of two volumes which aim to cover all established eukaryotic transcription factor systems that are direct targets for the signal transduction pathways. Leading molecular biologists contribute reviews on topics which take a broad view, and which should be of interest to students and advanced researchers in biology and medicine. Chapters attempt to answer such fundamental questions as: what is the signal and how and when is it produced? What is the receptor, and what further signalling molecules are involved? What is the biochemistry and molecular biology of the transcription factor that is the ultimate target of the signalling pathway? What is the physiological role of factor?
Download or read book Inducible Gene Expression written by P.A. Baeuerle and published by Birkhäuser. This book was released on 1994-12-22 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inducible Gene Expression Volume 1 written by P.A. Baeuerle and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells have evolved multiple strategies to adapt the composition and quality of their protein equipment to needs imposed by changes in intra- and extracellular conditions. The appearance of pro teins transmit ting novel functional properties to cells can be controlled at a transcrip tional, posttranscriptional, translational or posttranslational level. Extensive research over the past 15 years has shown that transcriptional regulation is used as the predominant strategy to control the production of new proteins in response to extracellular stimuli. At the level of gene transcription, the initiation ofmRNA synthesis is used most frequently to govern gene expression. The key elements controlling transcription initiation in eukaryotes are activator proteins (transactivators) that bind in a sequence-specific manner to short DNA sequences in the of genes. The activator binding sites are elements of larger proximity control units, ca lied promoters and enhancers, which bind many distinct proteins. These may synergize or negatively cooperate with the activators. The do novo binding of an activator to DNA or, if already bound to DNA, its functional activation is what ultimately turns on a high-level expression of genes. The activity of transactivators is controlled by signalling pathways and, in some cases, transactivators actively partici pate in signal transduction by moving from the cytoplasm into the nuc1eus. In this first volume of Inducible Gene Expression, leading scientists in the field review six eukaryotic transactivators that allow cells to respond to various extracellular stimuli by the expression of new proteins.
Download or read book Hormones and Signaling written by and published by Elsevier. This book was released on 1999-10-25 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones and Signaling focuses on the mechanisms of gene regulation at the cellular level. It also describes the actions of hormones in modulating gene regulation and animal development. - Glococorticoid and mineralcorticoid signaling - Orphan nuclear receptors - Nuclear receptor coactivators - Cytokines and STAT signaling - Coordination of cAMP signaling events through PKA anchoring - G protein-coupled extracellular Ca2+ (Ca2+0)-sensing receptor (CaR) - Pancreatic islet development - Genetic analysis of androgen receptors in development and disease - Antioprogestin regulable gene switch for induction of gene expression in vivo - Steroid receptor knockout model
Download or read book Inducible gene expression written by and published by . This book was released on 1995 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inducible Gene Expression Volume 1 written by P.A. Baeuerle and published by Birkhäuser. This book was released on 1994-12-22 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells have evolved multiple strategies to adapt the composition and quality of their protein equipment to needs imposed by changes in intra- and extracellular conditions. The appearance of pro teins transmit ting novel functional properties to cells can be controlled at a transcrip tional, posttranscriptional, translational or posttranslational level. Extensive research over the past 15 years has shown that transcriptional regulation is used as the predominant strategy to control the production of new proteins in response to extracellular stimuli. At the level of gene transcription, the initiation ofmRNA synthesis is used most frequently to govern gene expression. The key elements controlling transcription initiation in eukaryotes are activator proteins (transactivators) that bind in a sequence-specific manner to short DNA sequences in the of genes. The activator binding sites are elements of larger proximity control units, ca lied promoters and enhancers, which bind many distinct proteins. These may synergize or negatively cooperate with the activators. The do novo binding of an activator to DNA or, if already bound to DNA, its functional activation is what ultimately turns on a high-level expression of genes. The activity of transactivators is controlled by signalling pathways and, in some cases, transactivators actively partici pate in signal transduction by moving from the cytoplasm into the nuc1eus. In this first volume of Inducible Gene Expression, leading scientists in the field review six eukaryotic transactivators that allow cells to respond to various extracellular stimuli by the expression of new proteins.
Download or read book Hormones and Signaling written by Lutz Birnbaumer and published by Academic Press. This book was released on 1997-10-14 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones and Signaling focuses on the mechanism of gene regulation at the cellular level. It also covers the way hormones act to modulate gene regulation and animal development. Includes information on: Nuclear receptors, coactivators, and corepressors Membrane receptors, kinases, and phosphorylation on cascades Hormonal regulation of development Calcium channels and neurotransmitters Chromatin, transcription factors, and regulation of gene expression JAK/STAT pathways Hormone-regulated development and gene "knock-out"
Download or read book The Hormonal Control of Gene Transcription written by Philip Cohen and published by North Holland. This book was released on 1991 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nuclear Hormone Receptors written by Malcolm G. Parker and published by . This book was released on 1991 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the supergene family made up of those nuclear hormone receptors which recognize thyroid and steroid hormones, vitamen D and retinoic acid and which are characterized by their ability to bind both ligands and the genes which respond to them.
Download or read book Regulation of Gene Expression by Hormones written by Kenneth W. McKerns and published by Springer. This book was released on 1983-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Foundation for Biochemical Endocrinology is incorporated as a nonprofit research and educational organization. It is dedicated to the dissemination of knowledge, cooperative research programs, and cultural interaction on an international basis. The Foundation is concerned with both basic research and practical applications of biological knowledge to the betterment of humanity. Among our interests are global resource management, human reproduction, hormonal regulation of normal and cancer cells, study of aging and degenerative diseases, brain peptides, peptide neurotransmitter compounds, mechanism of action of hormones, peptide hormone synthesis, and recombinant DNA techniques. This monograph is the ninth sponsored by the Foundation in the Biochemical Endocrinology series. The previous four have been: Hormonally Active Brain Peptides: Structure and Function (1982), K. W. McKerns and V. Pantie, eds.; Reproductive Processes and Contraception (1981), K. W. McKerns, ed.; Synthesis and Release of Adenohypophyseal Hormones (1980), M. Jutisz and K. W. McKerns, eds.; and Structure and Function of the Gonadotropins (1978), K. W. McKerns, ed. These have all been published by Plenum Press.
Download or read book Mechanism of Steroid Hormone Regulation of Gene Transcription written by Ming-Jer Tsai and published by R. G. Landes. This book was released on 1994 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text summarizes recent progress on the regulation of target gene transcription by steroid hormone receptors. Steroid hormones travel via the blood stream to thier target cells which they enter by diffusion. Steroid hormone receptors exist in these cells in inactive forms either in the cytoplasm or nucleus. Upon binding to their respective hormone ligands, the receptors go through a transformation step and become activated. The activated receptor can then activate transcription of hormone response genes.
Download or read book Hormone Signaling written by Vincent Goffin and published by . This book was released on 2014-01-15 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms of Signal Transduction and Inducible Gene Expression written by and published by . This book was released on 2004 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
