Download or read book In Vitro Toxicity Testing written by John M. Frazier and published by CRC Press. This book was released on 1992-01-31 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the potential application of in vitro procedures to identify and quantify the toxicological risk to target organs associated with the use of commerical products and therapeutic drugs.;Revealing how the results of in vitro toxicity testing can be used in safety assessment, In Vitro Toxicity Testing: explores whether existing test methods can accomplish the necessary goals and, if not, what research is needed to make these techniques a practical reality; presents the current status of toxicity testing in the areas of hepatotoxicity, renal toxicity, ocular irritation, and many others; outlines the role of validation in technology transfer from the research laboratory to safety evaluation; examines testing strategies and regulatory acceptance and addresses common concerns about the ultimate utilization of available methods in chemical safety/hazard considerations; and analyzes the perspective of industrial and regulatory agencies on the application of in vitro toxicity testing.;Generously referenced with over 1400 literature citations, In Vitro Toxicity Testing is for academic, industrial, and regulatory toxicologists; applied, molecular, and cell biologists; pharmacologists; animal welfare activists; and graduate students in pharmacology and toxicology courses.
Download or read book TOX TIPS Toxicology Testing in Progress written by and published by . This book was released on 1987 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes notices of research projects submitted to the Smithsonian Science Information Exchange concerning toxicological testing.
Download or read book Validation and Regulatory Acceptance of Toxicological Test Methods written by DIANE Publishing Company and published by DIANE Publishing. This book was released on 1998-02 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dermal and Ocular Toxicology written by David W. Hobson and published by CRC Press. This book was released on 2020-11-25 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermal and Ocular Toxicology: Fundamentals and Methods is a procedurally-oriented volume of detailed methods and practical examples discussing the dermal and ocular aspects of toxicology. The book is divided into a dermal section and an ocular section. Each section begins with a chapter on the anatomy and physiology of each organ system and then progresses to more specialized chapters discussing such topics as the toxicological pathology of each system, state-of-the-art in vitro and in vivo evaluatory procedures, statistical considerations for test design and data interpretation, and the utilization of test findings. Test methods are provided for acute dermal exposure effects, dermal hypersensitivity and photoallergy assessment, dermal and ocular 0.pharmacokinetics, skin flap and skin grafting techniques, and in vitro alternative methods. This book can be used as an instructional text or as a sourcebook for practicing toxicologists, pharmacologists, industrial hygienists, occupational health professionals, and graduate students.
Download or read book Toxicological Principles for the Safety Assessment of Direct Food Additives and Color Additives Used in Food written by and published by . This book was released on 1993 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book In Vitro Toxicology written by Alan M. Goldberg and published by . This book was released on 1985 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug Safety Evaluation written by Shayne Cox Gad and published by John Wiley & Sons. This book was released on 2003-09-05 with total page 1020 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Safety Evaluation presents an all-inclusive, practical guide for those who are responsible for ensuring the safety of drugs and biologics for patients, for health care providers, for those involved in the manufacture of medicinal products, and for all those who need to understand how the safety of these products is evaluated. Individual chapters address specific approaches to evaluating hazards, including problems that are encountered and their solutions. Author Shayne Gad draws upon over twenty years of experience in toxicology, drug development, and risk assessment, explaining the scientific and philosophical bases for evaluating specific concerns (carcinogenicity, development toxicity, etc.) to provide both understanding and guidance for approaching new problems. Containing information specifically relevant to the pharmaceutical and biotechnology industries, Drug Safety Evaluation covers a wide variety of topics, including: Acute toxicity testing in pharmaceutical safety evaluation Genotoxicity Safety assessment of inhalant drugs Immunotoxicology in pharmaceutical development Large animal studies Evaluation of human tolerance and safety in clinical trials Drug Safety Evaluation provides a road map for safety assessment as an integral part of the development of new drugs and therapeutics.
Download or read book Alternative Methodologies for the Safety Evaluation of Chemicals in the Cosmetic Industry written by Nicola Loprieno and published by CRC Press. This book was released on 2019-08-15 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1995: Alternative Methodologies for the Safety Evaluation of Chemicals in the Cosmetic Industry presents a categorization and collection of information available for the evaluation of safety using in vitro techniques. It offers a comprehensive and complete look at the entire field. In doing so, the author provides the foundation for the next phase of significant growth for this discipline.
Download or read book Aquatic Toxicology and Hazard Assessment written by William J. Adams and published by ASTM International. This book was released on 1988 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Experimentation written by Kathrin Herrmann and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Experimentation: Working Towards a Paradigm Change critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.
Download or read book Biologic Markers in Reproductive Toxicology written by National Research Council and published by National Academies Press. This book was released on 1989-02-01 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does exposure to environmental toxicants inhibit our ability to have healthy children who develop normally? Biologic markersâ€"indicators that can tell us when environmental factors have caused a change at the cellular or biochemical level that might affect reproductive abilityâ€"are a promising tool for research aimed at answering that important question. Biologic Markers in Reproductive Toxicology examines the potential of these markers in environmental health studies; clarifies definitions, underlying concepts, and possible applications; and shows the benefits to be gained from their use in reproductive and neurodevelopmental research.
Download or read book Validation and Regulatory Acceptance of Toxicological Test Methods written by and published by . This book was released on 1997 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Environmental Health Perspectives written by and published by . This book was released on 1993 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alternatives to Animal Use in Research Testing and Education written by and published by . This book was released on 1986 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Manual of Online Search Strategies written by C.J. Armstrong and published by Routledge. This book was released on 2018-12-20 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in 1992, like the first, this second edition is not intended as introductory textbook command-driven, Boolean searching. It is targeted at online searchers who already have some knowledge of command languages and may be proficient searchers on databases in one or two subject areas, but when required to venture into new and less familiar territory still need guidance. It is also offered to end users who possess the subject expertise but lack of information retrieval know-how. The Manual is offered as a guide to database selection and a navigational aid through the twists and turns of the retrieval maze; at least some of the dead ends and backtracking may thereby be avoided. This volume, written by experts in their various fields, deals with the subject coverage and record structures of specific databases, offers comparisons between databases (context, indexing procedures, updating policies, etc.), discusses the choice between online and CD-ROM sources (and between hosts if online is selected), and illustrates strategies with numerous search extracts.
Download or read book Accessions Books Selected Articles Periodicals written by Organisation for Economic Co-operation and Development. Library and published by . This book was released on 1988 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alternative Testing Methodologies written by and published by . This book was released on 1998 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
