Download or read book Impulsive Mathematical Models of Endocrine Regulation written by Alexander Medvedev and published by Academic Press. This book was released on 2020-12-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impulsive Mathematical Models of Endocrine Regulation demonstrates recently-developed mathematical models portraying pulse-modulated regulation in endocrine systems, taking a pragmatic engineering stance by starting with the necessary theoretical background on analytical tools, progressing through a number of mathematical models of increasing complexity, and illustrating the feasibility and fidelity of the mathematical constructs on actual biological data. Compared to a commonplace, theory-oriented book on dynamical systems and control which typically presents a group of design or analysis techniques, the book originates from a real-life problem of fundamental value and introduces mathematical tools that have specifically been devised to solve it. Presents results on impulsive mathematical models of endocrine regulation in a systematic, comprehensive and accessible manner Introduces researchers and engineers specializing in dynamical systems to a rapidly-growing topic Provides biomedical engineering and biological researchers with mathematical modeling and analysis tools for continuous systems using episodic feedback exemplified by non-basal endocrine regulation
Download or read book The Mathematical Modeling of Metabolic and Endocrine Systems written by Ewart R. Carson and published by . This book was released on with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mathematical Modeling of the Hormonal Regulation of Food Intake and Body Weight written by Marine Jacquier and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The regulation of food intake and energy expenditure usually limits important loss or gain of body weight. Hormones (leptin, ghrelin, insulin) and nutrients (glucose, triglycerides) are among the main regulators of food intake. Leptin is also involved in leptin resistance, often associated with obesity and characterized by a reduced efficacy to regulate food intake. Mathematical models describing the dynamics of body weight have been used to assist clinical weight loss interventions or to study an experimentally inaccessible phenomenon, such as starvation experiments in humans. Modeling of the effect of hormones on body weight has however been largely ignored.In this thesis, we first consider a model of body weight regulation by hormones in rats, made of nonlinear differential equations. It describes the dynamics of food intake, body weight and energy expenditure, regulated by leptin, ghrelin and glucose. It is able to reproduce and predict the evolution of body weight and food intake in rats submitted to different patterns of caloric restriction, showing the importance of the adaptation of energy expenditure. Second, we introduce the first model of leptin resistance development, based on the regulation of food intake by leptin and leptin receptors. We show that healthy individuals may become leptin resistant and obese due to perturbations in food intake or leptin concentration. Finally, modifications of these models are presented, characterized by simplified yet realistic body weight dynamics. The models prove able to fit the previous, as well as new sets of experimental data and allow to build a complete model combining both previous models regulatory mechanisms.
Download or read book Hormones As Tokens of Selection written by Hugo van den Berg and published by CRC Press. This book was released on 2019 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones as Tokens of Selection addresses deep questions in biology: How are biological systems controlled? How can one formulate general theories of homeostasis and control and instantiate such theories in mathematical models? How can one use evolutionary arguments to guide our answers to these questions, recognising that the control mechanisms themselves are a product of evolution? Biological systems are exceptionally varied and extremely difficult to understand, because they are complex and experimentation remains limited relative to the challenges at hand. Moreover, biological phenomena occur at a wide range of temporal and spatial scales. Such a deeply convoluted subject calls for a unifying and coherent theoretical foundation -- one which recognises and departs from the primary importance of mathematical modelling and key physicochemical principles to theory formation in the life sciences. This Focus monograph proposes and outlines such a foundation, departing from the deceptively simple proposition that hormones are tokens of evolutionary pressures. Features Provides a coherent and unified approach to a multifaceted problem Pays close attention to both the biological and mathematical modelling aspects of the subject matter, exploring the philosophical background where appropriate Written in a concise and innovative style
Download or read book Signal and Image Analysis for Biomedical and Life Sciences written by Changming Sun and published by Springer. This book was released on 2014-11-07 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an emphasis on applications of computational models for solving modern challenging problems in biomedical and life sciences, this book aims to bring collections of articles from biologists, medical/biomedical and health science researchers together with computational scientists to focus on problems at the frontier of biomedical and life sciences. The goals of this book are to build interactions of scientists across several disciplines and to help industrial users apply advanced computational techniques for solving practical biomedical and life science problems. This book is for users in the fields of biomedical and life sciences who wish to keep abreast with the latest techniques in signal and image analysis. The book presents a detailed description to each of the applications. It can be used by those both at graduate and specialist levels.
Download or read book Applied Biomechatronics Using Mathematical Models written by Jorge Garza Ulloa and published by Academic Press. This book was released on 2018-06-16 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied Biomechatronics Using Mathematical Models provides an appropriate methodology to detect and measure diseases and injuries relating to human kinematics and kinetics. It features mathematical models that, when applied to engineering principles and techniques in the medical field, can be used in assistive devices that work with bodily signals. The use of data in the kinematics and kinetics analysis of the human body, including musculoskeletal kinetics and joints and their relationship to the central nervous system (CNS) is covered, helping users understand how the complex network of symbiotic systems in the skeletal and muscular system work together to allow movement controlled by the CNS. With the use of appropriate electronic sensors at specific areas connected to bio-instruments, we can obtain enough information to create a mathematical model for assistive devices by analyzing the kinematics and kinetics of the human body. The mathematical models developed in this book can provide more effective devices for use in aiding and improving the function of the body in relation to a variety of injuries and diseases. Focuses on the mathematical modeling of human kinematics and kinetics Teaches users how to obtain faster results with these mathematical models Includes a companion website with additional content that presents MATLAB examples
Download or read book The Mathematical Modeling of Metabolic and Endocrine Systems written by Ewart R. Carson and published by . This book was released on 1983-02-25 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces the concepts, methods and techniques of model formulation, identification, and validation as applicable to metabolic and endocrine processes. Shows how modeling can be used to provide a concise description of complex dynamic processes, to test hypotheses concerning physiological and biochemical structure, and to estimate physiological quantities (parameters) that otherwise would not be directly accessible to measurement. Includes numerous examples and case studies.
Download or read book Issues in Systems Engineering 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Systems Engineering / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Systems and Control Engineering. The editors have built Issues in Systems Engineering: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Systems and Control Engineering in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Systems Engineering: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Oxford Textbook of Endocrinology and Diabetes written by John A.H. Wass and published by Oxford University Press, USA. This book was released on 2011-07-28 with total page 2158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.
Download or read book Modelling Methodology for Physiology and Medicine written by Ewart Carson and published by Elsevier. This book was released on 2000-12-31 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modelling Methodology for Physiology and Medicine offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modelling methodology that is widely applicable to physiology and medicine. The book opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. Builds upon and enhances the readers existing knowledge of modelling methodology and practice Editors are internationally renowned leaders in their respective fields
Download or read book Chaotic Systems with Multistability and Hidden Attractors written by Xiong Wang and published by Springer Nature. This book was released on 2021-12-01 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a collection of new articles written by world-leading experts and active researchers to present their recent finding and progress in the new area of chaotic systems and dynamics, regarding emerging subjects of unconventional chaotic systems and their complex dynamics.It guide readers directly to the research front of the new scientific studies. This book is unique of its kind in the current literature, presenting broad scientific research topics including multistability and hidden attractors in unconventional chaotic systems, such as chaotic systems without equilibria, with only stable equilibria, with a curve or a surface of equilibria. The book describes many novel phenomena observed from chaotic systems, such as non-Shilnikov type chaos, coexistence of different types of attractors, and spontaneous symmetry breaking in chaotic systems. The book presents state-of-the-art scientific research progress in the field with both theoretical advances and potential applications. This book is suitable for all researchers and professionals in the areas of nonlinear dynamics and complex systems, including research professionals, physicists, applied mathematicians, computer scientists and, in particular, graduate students in related fields.
Download or read book NASA SP written by and published by . This book was released on 1962 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Transforming the Workforce for Children Birth Through Age 8 written by National Research Council and published by National Academies Press. This book was released on 2015-07-23 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children are already learning at birth, and they develop and learn at a rapid pace in their early years. This provides a critical foundation for lifelong progress, and the adults who provide for the care and the education of young children bear a great responsibility for their health, development, and learning. Despite the fact that they share the same objective - to nurture young children and secure their future success - the various practitioners who contribute to the care and the education of children from birth through age 8 are not acknowledged as a workforce unified by the common knowledge and competencies needed to do their jobs well. Transforming the Workforce for Children Birth Through Age 8 explores the science of child development, particularly looking at implications for the professionals who work with children. This report examines the current capacities and practices of the workforce, the settings in which they work, the policies and infrastructure that set qualifications and provide professional learning, and the government agencies and other funders who support and oversee these systems. This book then makes recommendations to improve the quality of professional practice and the practice environment for care and education professionals. These detailed recommendations create a blueprint for action that builds on a unifying foundation of child development and early learning, shared knowledge and competencies for care and education professionals, and principles for effective professional learning. Young children thrive and learn best when they have secure, positive relationships with adults who are knowledgeable about how to support their development and learning and are responsive to their individual progress. Transforming the Workforce for Children Birth Through Age 8 offers guidance on system changes to improve the quality of professional practice, specific actions to improve professional learning systems and workforce development, and research to continue to build the knowledge base in ways that will directly advance and inform future actions. The recommendations of this book provide an opportunity to improve the quality of the care and the education that children receive, and ultimately improve outcomes for children.
Download or read book Theory Of Impulsive Differential Equations written by Vangipuram Lakshmikantham and published by World Scientific. This book was released on 1989-05-01 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many evolution processes are characterized by the fact that at certain moments of time they experience a change of state abruptly. These processes are subject to short-term perturbations whose duration is negligible in comparison with the duration of the process. Consequently, it is natural to assume that these perturbations act instantaneously, that is, in the form of impulses. It is known, for example, that many biological phenomena involving thresholds, bursting rhythm models in medicine and biology, optimal control models in economics, pharmacokinetics and frequency modulated systems, do exhibit impulsive effects. Thus impulsive differential equations, that is, differential equations involving impulse effects, appear as a natural description of observed evolution phenomena of several real world problems.
Download or read book Research Awards Index written by and published by . This book was released on 1982 with total page 1170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Government Reports Announcements written by and published by . This book was released on 1975-03 with total page 898 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1840 pages. Available in PDF, EPUB and Kindle. Book excerpt: