Download or read book Improving Precision of Deformable Image Registration written by Keyur Devendra Shah and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deformable image registration (DIR) has various applications in medical image analysis such as in adaptive radiotherapy (ART) and multi-atlas segmentation. ART uses DIR to warp the dose from the daily cone-beam CT (CBCT) image to the planning computed tomography (CT) image to accommodate anatomical changes that occur between dose planning and dose delivery. DIR aims to find a geometric transformation between corresponding image data and brings them into a common coordinate frame. DIR is an inherently ill-posed problem that lacks a unique mapping between the voxels of the two images being registered. As such, one must regularize the registration to achieve physically meaningful transforms. The regularization penalty is usually a function of derivatives of the displacement vector field and can be calculated either analytically or numerically. The numerical approach, however, is computationally expensive depending on the image size, and therefore a computationally efficient analytical framework has been developed. Cubic B-splines were used to model the displacement vector field. A generalized mathematical framework was developed that supports five distinct regularizers: diffusion, curvature, linear elastic, third-order, and total displacement. The approach was validated by comparing each regularizer with its numerical counterpart in terms of accuracy. Benchmarking results show that the analytic solutions run significantly faster -- up to two orders of magnitude -- than finite differencing-based numerical implementations. Additionally, the cost function used in the DIR optimization process is a global, low-level cost function. It fails to accurately align high-level image structures such as organs at risk (OARs). DIR accuracy can be improved locally by adding high-level structures such as contours and landmark points. A hybrid image similarity metric that incorporates a point-to-distance map (PD) metric was developed. Given a pair of segmented images, structures on the fixed image are represented as sets of points while structures on the moving image are described as distance maps. The total distance of all fixed points to their associated boundaries on the moving image constitutes the PD metric, which is combined with the more traditional intensity similarity metric between the fixed and moving images. The approach was validated using the pelvic reference dataset wherein the prostate, bladder, and rectum were manually segmented from the CT and CBCT images by a medical expert to obtain the segmented fixed and moving images. The accuracy of the deformable registration was quantified using the Dice Similarity Coefficient (DSC) and 95% Hausdorff Distance (95% HD), with and without the PD metric. Results demonstrate a much-improved overlap between the fixed and warped contours once the PD metric was applied. Moreover, the computational overhead associated with adding the PD metric was minimal. Finally, to circumvent the need for a medical expert to manually segment the structures, a 3-D U-Net architecture was used to generate structures to be used with the PD Metric calculations. An image-to-image translation network is trained using a CycleGAN to domain adapt between CT and CBCT images to assist the auto-segmentation process. Experiments are performed to compare the DIR accuracy with the 3-D U-Net generated structures and the manually segmented structures. Results demonstrate that the auto-segmented images improve the DIR accuracy equally when using manually segmented images. This helps in reducing manual overhead associated with segmenting the images and thus increases the end-to-end performance of the DIR algorithm making it suitable for clinical use.

Download or read book Medical Image Registration written by Joseph V. Hajnal and published by CRC Press. This book was released on 2001-06-27 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Image registration is the process of systematically placing separate images in a common frame of reference so that the information they contain can be optimally integrated or compared. This is becoming the central tool for image analysis, understanding, and visualization in both medical and scientific applications. Medical Image Registration provid

Download or read book Adaptive Radiation Therapy written by X. Allen Li and published by CRC Press. This book was released on 2011-01-27 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern medical imaging and radiation therapy technologies are so complex and computer driven that it is difficult for physicians and technologists to know exactly what is happening at the point-of-care. Medical physicists responsible for filling this gap in knowledge must stay abreast of the latest advances at the intersection of medical imaging an

Download or read book High Performance Deformable Image Registration Algorithms for Manycore Processors written by James Shackleford and published by Newnes. This book was released on 2013-06-28 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: High Performance Deformable Image Registration Algorithms for Manycore Processors develops highly data-parallel image registration algorithms suitable for use on modern multi-core architectures, including graphics processing units (GPUs). Focusing on deformable registration, we show how to develop data-parallel versions of the registration algorithm suitable for execution on the GPU. Image registration is the process of aligning two or more images into a common coordinate frame and is a fundamental step to be able to compare or fuse data obtained from different sensor measurements. Extracting useful information from 2D/3D data is essential to realizing key technologies underlying our daily lives. Examples include autonomous vehicles and humanoid robots that can recognize and manipulate objects in cluttered environments using stereo vision and laser sensing and medical imaging to localize and diagnose tumors in internal organs using data captured by CT/MRI scans. - Demonstrates how to redesign widely used image registration algorithms so as to best expose the underlying parallelism available in these algorithms - Shows how to pose and implement the parallel versions of the algorithms within the single instruction, multiple data (SIMD) model supported by GPUs - Provides Programming "tricks" that can help readers develop other image processing algorithms, including registration algorithms for the GPU

Download or read book Strategies for Adaptive Radiation Therapy written by Junyi Xia and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: ABSTRACT: Image guided radiation therapy (IGRT) requires developing advanced methods for target localization. Once target motion is identified, the patient specific treatment margin can be incorporated into the treatment planning, accurately delivering the radiation dose to the target and minimizing the dose to the normal tissues. Deformable image registration (DIR) has become an indispensable tool to analyze target motion and measure physiological change by temporal imaging or time series volumetric imaging, such as four-dimensional computed tomography (4DCT). Current DIR algorithms suffer from inverse inconsistency, where the deformation mapping is not unique after switching the order of the images. Moreover, long computation time of current DIR implementation limits its clinical application to offline analysis. This dissertation makes several major contributions: First, an inverse consistent constraint (ICC) is proposed to constrain the uniqueness of the correspondence between image pairs. The proposed ICC has the advantage of 1) improving registration accuracy and robustness, 2) not requiring explicitly computing the inverse of the deformation field, and 3) reducing the inverse consistency error (ICE). Moreover, a variational registration model, based on the maximum likelihood estimation, is proposed to accelerate the algorithm convergence and allow for inexact image pixel matching within an optimized variation for noisy image pairs.

Download or read book GPU Computing Gems Emerald Edition written by and published by Elsevier. This book was released on 2011-01-13 with total page 889 pages. Available in PDF, EPUB and Kindle. Book excerpt: GPU Computing Gems Emerald Edition offers practical techniques in parallel computing using graphics processing units (GPUs) to enhance scientific research. The first volume in Morgan Kaufmann's Applications of GPU Computing Series, this book offers the latest insights and research in computer vision, electronic design automation, and emerging data-intensive applications. It also covers life sciences, medical imaging, ray tracing and rendering, scientific simulation, signal and audio processing, statistical modeling, video and image processing. This book is intended to help those who are facing the challenge of programming systems to effectively use GPUs to achieve efficiency and performance goals. It offers developers a window into diverse application areas, and the opportunity to gain insights from others' algorithm work that they may apply to their own projects. Readers will learn from the leading researchers in parallel programming, who have gathered their solutions and experience in one volume under the guidance of expert area editors. Each chapter is written to be accessible to researchers from other domains, allowing knowledge to cross-pollinate across the GPU spectrum. Many examples leverage NVIDIA's CUDA parallel computing architecture, the most widely-adopted massively parallel programming solution. The insights and ideas as well as practical hands-on skills in the book can be immediately put to use. Computer programmers, software engineers, hardware engineers, and computer science students will find this volume a helpful resource. For useful source codes discussed throughout the book, the editors invite readers to the following website: ..." - Covers the breadth of industry from scientific simulation and electronic design automation to audio / video processing, medical imaging, computer vision, and more - Many examples leverage NVIDIA's CUDA parallel computing architecture, the most widely-adopted massively parallel programming solution - Offers insights and ideas as well as practical "hands-on" skills you can immediately put to use

Download or read book Image Registration for Remote Sensing written by Jacqueline Le Moigne and published by Cambridge University Press. This book was released on 2011-03-24 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a summary of current research in the application of image registration to satellite imagery. Presenting algorithms for creating mosaics and tracking changes on the planet's surface over time, it is an indispensable resource for researchers and advanced students in Earth and space science, and image processing.

Download or read book Image Processing in Radiation Therapy written by Kristy K. Brock and published by CRC Press. This book was released on 2016-04-19 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Images from CT, MRI, PET, and other medical instrumentation have become central to the radiotherapy process in the past two decades, thus requiring medical physicists, clinicians, dosimetrists, radiation therapists, and trainees to integrate and segment these images efficiently and accurately in a clinical environment. Image Processing in Radiation

Download or read book An Algorithm to Improve Deformable Image Registration Accuracy in Challenging Cases of Locally advanced Non small Cell Lung Cancer written by Christopher Logan Guy and published by . This book was released on 2017 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: A common co-pathology of large lung tumors located near the central airways is collapse of portions of lung due to blockage of airflow by the tumor. Not only does the lung volume decrease as collapse occurs, but fluid from capillaries also fills the space no longer occupied by air, greatly altering tissue appearance. During radiotherapy, typically administered to the patient over multiple weeks, the tumor can dramatically shrink in response to the treatment, restoring airflow to the lung sections which were collapsed when therapy began. While return of normal lung function is a positive development, the change in anatomy presents problems for future radiation sessions since the treatment was planned on lung geometry which is no longer accurate. The treatment must be adapted to the new lung state so that the radiation continues to accurately target the tumor while safely avoiding healthy tissue. However, to account for the dose delivered previously, correspondences of anatomy between the former image when the lung was collapsed and the re-expanded lung in a current image must be obtained. This process, known as deformable image registration, is performed by registration software. Most registration algorithms assume that identical anatomy is contained in the images and that intensities of corresponding image elements are similar; both assumptions are untrue when collapsed lung re-expands. This work was to develop an algorithm which accurately registers images in the presence of lung expansion. The lung registration method matched CT images of patients aided by vessel enhancement and information of individual lobe boundaries. The algorithm was tested on eighteen patients with lung collapse using physician-specified correspondences to measure registration error. The image registration algorithm developed in this work which was designed for challenging lung patients resulted in accuracy comparable to that of other methods when large lung changes are absent.

Download or read book Medical Image Analysis written by Alejandro Frangi and published by Academic Press. This book was released on 2023-09-20 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Image Analysis presents practical knowledge on medical image computing and analysis as written by top educators and experts. This text is a modern, practical, self-contained reference that conveys a mix of fundamental methodological concepts within different medical domains. Sections cover core representations and properties of digital images and image enhancement techniques, advanced image computing methods (including segmentation, registration, motion and shape analysis), machine learning, how medical image computing (MIC) is used in clinical and medical research, and how to identify alternative strategies and employ software tools to solve typical problems in MIC. - An authoritative presentation of key concepts and methods from experts in the field - Sections clearly explaining key methodological principles within relevant medical applications - Self-contained chapters enable the text to be used on courses with differing structures - A representative selection of modern topics and techniques in medical image computing - Focus on medical image computing as an enabling technology to tackle unmet clinical needs - Presentation of traditional and machine learning approaches to medical image computing

Download or read book Biomedical Imaging written by Youxin Mao and published by BoD – Books on Demand. This book was released on 2010-03-01 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical imaging is becoming an indispensable branch within bioengineering. This research field has recently expanded due to the requirement of high-level medical diagnostics and rapid development of interdisciplinary modern technologies. This book is designed to present the most recent advances in instrumentation, methods, and image processing as well as clinical applications in important areas of biomedical imaging. It provides broad coverage of the field of biomedical imaging, with particular attention to an engineering viewpoint. The goal of the book is to provide a wide-ranging forum in the biomedical imaging field that integrates interdisciplinary research and development of interest to scientists, engineers, teachers, students, and clinical providers.

Download or read book Biomedical Image Registration written by Žiga Špiclin and published by Springer Nature. This book was released on 2020-06-09 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 9th International Workshop on Biomedical Image Registration, WBIR 2020, which was supposed to be held in Portorož, Slovenia, in June 2020. The conference was postponed until December 2020 due to the COVID-19 pandemic. The 16 full and poster papers included in this volume were carefully reviewed and selected from 22 submitted papers. The papers are organized in the following topical sections: Registration initialization and acceleration, interventional registration, landmark based registration, multi-channel registration, and sliding motion.

Download or read book Artificial Intelligence for Precision Medicine written by Jun Deng and published by Frontiers Media SA. This book was released on 2022-02-16 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Deep Learning in Medical Image Analysis and Multimodal Learning for Clinical Decision Support written by M. Jorge Cardoso and published by Springer. This book was released on 2017-09-07 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed joint proceedings of the Third International Workshop on Deep Learning in Medical Image Analysis, DLMIA 2017, and the 6th International Workshop on Multimodal Learning for Clinical Decision Support, ML-CDS 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Québec City, QC, Canada, in September 2017. The 38 full papers presented at DLMIA 2017 and the 5 full papers presented at ML-CDS 2017 were carefully reviewed and selected. The DLMIA papers focus on the design and use of deep learning methods in medical imaging. The ML-CDS papers discuss new techniques of multimodal mining/retrieval and their use in clinical decision support.

Download or read book Biomedical Image Processing written by Thomas Martin Deserno and published by Springer Science & Business Media. This book was released on 2011-03-01 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: In modern medicine, imaging is the most effective tool for diagnostics, treatment planning and therapy. Almost all modalities have went to directly digital acquisition techniques and processing of this image data have become an important option for health care in future. This book is written by a team of internationally recognized experts from all over the world. It provides a brief but complete overview on medical image processing and analysis highlighting recent advances that have been made in academics. Color figures are used extensively to illustrate the methods and help the reader to understand the complex topics.

Download or read book Computational Science and Its Applications ICCSA 2020 written by Osvaldo Gervasi and published by Springer Nature. This book was released on 2020-10-01 with total page 1003 pages. Available in PDF, EPUB and Kindle. Book excerpt: The seven volumes LNCS 12249-12255 constitute the refereed proceedings of the 20th International Conference on Computational Science and Its Applications, ICCSA 2020, held in Cagliari, Italy, in July 2020. Due to COVID-19 pandemic the conference was organized in an online event. Computational Science is the main pillar of most of the present research, industrial and commercial applications, and plays a unique role in exploiting ICT innovative technologies. The 466 full papers and 32 short papers presented were carefully reviewed and selected from 1450 submissions. Apart from the general track, ICCSA 2020 also include 52 workshops, in various areas of computational sciences, ranging from computational science technologies, to specific areas of computational sciences, such as software engineering, security, machine learning and artificial intelligence, blockchain technologies, and of applications in many fields.

Download or read book IMRT IGRT SBRT written by John Meyer and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: New high-precision technologies for the planning and delivery of radiotherapy are major advances in cancer treatment. This volume is a comprehensive guidebook to these new technologies and the many clinical treatment programs that bring them into practical use. Advances in intensity modulated radiation therapy (IMRT), 4D and adaptive treatment planning are clearly explained, and the new target localization and image-guided radiotherapy (IGRT) systems are comprehensively reviewed. Clinical tutorials fully illustrate the target definitions for the major cancer sites, and techniques for organ motion management are shown. In addition, chapters explore the technical basis for stereotactic body radiotherapy (SBRT) and the latest clinical experience with it for most organ sites.