Download or read book Immunology of Psoriatic Disease written by Eva Reali and published by Frontiers Media SA. This book was released on 2019-07-31 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psoriasis is a chronically relapsing inflammatory skin disorder affecting about 2% of the worldwide population. The disease is associated with important systemic manifestations, including cardiovascular comorbidities and metabolic syndrome. In addition, about 30% of patients develop joint inflammation known as psoriatic arthritis (PsA). Our knowledge on the pathogenesis of psoriasis has dramatically expanded in the last decade, suggesting the existence (or co-existence) of both auto-immune and auto-inflammatory components. Skin lesions develop from a complex interplay between keratinocytes, vascular endothelium, dendritic cells, and T cells, generating a self-sustaining inflammatory cycle. Within this cycle, epidermal CD8+ T lymphocytes specific for self-antigens may represent the major autoimmune mechanism. Despite the recent progress in the comprehension of the pathogenesis of psoriasis many questions remain open, ranging from the plaque-initiating events to the characterization of the autoimmune /autoinflammatory components of the disease. The mechanisms that link cutaneous psoriasis to its extra-cutaneous and systemic manifestations also remain vague. In this Research Topic we invited top scientists to summarize the front-line research in the field of immunology of cutaneous psoriasis and its systemic and joint manifestations. Our intention was to integrate the pillar concepts of psoriasis immunopathology with the most novel insights, aiming at providing an advanced view of this rapidly evolving and fascinating field.

Download or read book Psoriasis and Psoriatic Arthritis written by Kenneth B. Gordon and published by Springer Science & Business Media. This book was released on 2005-02-16 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: First comprehensive book on this topic: Textbooks on psoriasis and psoriatic arthritis in one Newest information on Psoriasis. Written by well-known international experts. Well-structured with reader-friendly format.

Download or read book Psoriasis and Psoriatic Arthritis written by Siba P. Raychaudhuri and published by CRC Press. This book was released on 2017-12-15 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psoriasis is a life-long chronic autoimmune disease characterized by thick scaly skin lesions and often associated with severe arthritis. In psoriasis, lesions skin cells, keratinocytes, grow too quickly, resulting in thick, white, silvery or red patches on skin. Normal skin cells grow gradually and flake off about every four weeks, but psoriasis causes new skin cells to move rapidly to the surface of the skin in days rather than weeks. Psoriasis symptoms often appear on the elbows, scalp, feet, knees, hands, or lower back, or as flaking or patches on the skin. It is most common in adults, but teenagers and children can also suffer from psoriasis. Psoriasis is not only a skin condition; it is a chronic disease of the immune system. Chronic psoriasis is associated with other health conditions such as psoriatic arthritis, several inflammatory disorders, type 2 diabetes, and cardiovascular disease. This book provides extensive coverage of psoriasis and psoriatic arthritis. It features information on epidemiology and etiology of psoriasis, pathogenesis, genetics of psoriasis, clinical manifestations, and treatment options using cutting-edge drugs including adalimumab and tofacitinib. Natural phytochemicals and nutraceuticals have demonstrated efficacy in ameliorating psoriasis. The book dedicates comprehensive coverage of nutraceutical therapeutic options including antioxidants, bioactive peptides, carotenoids, alpha lipoic acid, curcumin, and whey protein. These inexpensive natural therapeutics are not associated with any known adverse side effects.

Download or read book Recent Advances In Psoriasis The Role Of The Immune System written by Barbara S Baker and published by World Scientific. This book was released on 2000-04-11 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the evidence for the belief that psoriasis is a disease of abnormal keratinocyte proliferation induced by T cells. The latest approaches to investigating the immunopathogenesis of this disease, and a review of previous findings, are presented to give an overall picture of the current knowledge in this field. Each topic is discussed in detail, clearly illustrated and well referenced. The book should prove invaluable to clinical dermatologists, and researchers in the fields of immunology and dermatology who have an interest in skin diseases.

Download or read book Advances in Psoriasis written by Jeffrey M. Weinberg and published by Springer. This book was released on 2014-08-28 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has become increasingly clear that psoriatic disease, both of the skin and joints, can be a significant diagnostic and therapeutic challenge for the physician and a debilitating illness for the patient. Genetic and immunologic advances have increased our understanding of the pathophysiology of psoriasis and psoriatic arthritis and there is a need for practically oriented evidence based references to describe the management options open to clinicians. The speed at which developments are occurring in the field also necessitates a novel approach to keeping up with these changes in practice and the need is for a reference that that be updated regularly as the subject requires. Psoriasis is an incredibly fast-moving discipline within dermatology. Guidelines, treatment options and management all change at incredible speed. There is a requirement to provide a comprehensive reference resource to provide practical, user friendly information for the dermatology profession to aid in the decision-making process. Psoriasis is a graphical subdiscipline of medicine and therefore this will have copious illustrations. As a fast moving discipline the emphasis must be on annual updates to ensure that readers are kept up to date on the important areas of development.

Download or read book Psoriasis written by Anca Chiriac and published by BoD – Books on Demand. This book was released on 2017-07-05 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2014, psoriasis was recognized as a serious noncommunicable disease in the World Health Assembly Resolution WHA67.9, with a great negative impact on patients' quality of life. Psoriasis is a worldwide chronic disease, affecting all ages and all races, and a serious global health problem. Psoriasis is a complex disease with still unknown etiology and no specific curative treatment. The chapters provide comprehensive and new description of some issues related to psoriasis research and for understanding of clinical correlations, genetic aspects, experimental research, and potential therapeutic interventions. The book could be a source of information for clinicians and researchers from different fields in raising awareness of the disease.

Download or read book AUTOIMMUNITY IN PSORIASIS written by Ernst H. Beutner and published by Springer. This book was released on 1982 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Treatment of Psoriasis written by Jeffrey M. Weinberg and published by Springer Science & Business Media. This book was released on 2008-09-16 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an in-depth overview of the current state of psoriasis and its management. It reviews the clinical manifestations of psoriasis as well as psoriatic arthritis and emphasizes the evolving paradigm of therapy. Coverage includes topical and ultraviolet therapies as well as traditional systemic therapy. In addition, a major focus of the volume is on biologic therapies. New agents in development are also reviewed.

Download or read book Psoriatic Arthritis An Issue of Rheumatic Disease Clinics 41 4 written by Christopher T. Ritchlin and published by Elsevier Health Sciences. This book was released on 2016-01-07 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some people with psoriasis can also develop psoriatic arthritis, when the immune system attacks the joints as well, causing inflammation. Like psoriasis, psoriatic arthritis symptoms flare and subside, vary from person to person, and even change locations in the same person over time. Psoriatic arthritis can affect any joint in the body, and it may affect just one joint, several joints or multiple joints. For example, it may affect one or both knees. This issue will include articles on Genetic and Epigenetic aspects of psoriatic arthritis, Clinical features and diagnostic considerations in psoriatic arthritis, Natural history, prognosis and socioeconomic aspects of psoriatic arthritis, Etiology and pathogenesis of psoriasis and many more!

Download or read book Comorbidity in Rheumatic Diseases written by Yasser El Miedany and published by Springer. This book was released on 2017-08-24 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores comorbidity in patients with rheumatic diseases and details both care and treatment options in standard clinical practice. Patients with rheumatic diseases are clinically complex, and the interplay of their disease activity with associated conditions may lead to increased morbidity and mortality. Recently there have been major advances in the management of rheumatic diseases, however, without addressing the potential comorbid conditions, including cardiovascular disease; pulmonary disease; and depression; outcomes remain poor. ​​​ With its 19 chapters, covering the management of major rheumatic diseases (e.g. rheumatoid arthritis, systemic lupus erythematosus , and osteoarthritis), potential comorbidities and treatment recommendations, as well as possible interactions between conditions; this book addresses the gap between textbook medicine and day to day patients' care. Authors also discuss the new hot issue of the comorbidity index, comparing the standard tools to the recently developed indices and how they can assist the rheumatologists in determining disease burden, prognosis, and comorbidity probability. This book is an ideal clinical guide and reference that enables rheumatologists, internal medicine physicians, and residents to address the full clinical expression of these rheumatic diseases with views towards prevention or early management of comorbid conditions.

Download or read book Psoriatic and Reactive Arthritis E Book written by Christopher T. Ritchlin and published by Elsevier Health Sciences. This book was released on 2007-06-25 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new companion to Hochberg et al.'s Rheumatology masterwork focuses on the momentous recent advances in our understanding of the genetics and immunology of psoriatic and reactive arthritis, and their implications for diagnosis and management. Leading international authorities explore new concepts in genetic and pathogenic mechanisms and early diagnosis; provide comprehensive, well-illustrated coverage of clinical features; evaluate the very latest therapeutic options, including biologics; and discuss clinical outcome measures. Examines the very latest pathogenic mechanisms and diagnostic criteria, providing the necessary tools for early diagnosis and monitoring of disease progression. Offers comprehensive coverage of the clinical manifestations of psoriatic and reactive arthritis, including a ‘mini atlas' of color plates. Examines the pros and cons of the available therapeutic options, including the very latest biological as well as traditional therapies. Includes practical discussions of clinical outcome measures, delivering ongoing tools for assessment of function, disease activity, and quality of life.

Download or read book A Comprehensive Rheumatological and Immunological Approach to Diagnosis of Psoriatic Arthritis written by Syuichi Koarada and published by Cambridge Scholars Publishing. This book was released on 2020-07-31 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed investigation of psoriatic arthritis (PsA), a chronic rheumatic disease that involves joints, entheses and skin. Although PsA has been considered as a milder form of arthritis, in the past decade, it has been proven to be a potentially serious disease like rheumatoid arthritis (RA). Radiographic findings, clinical presentation and laboratory tests reveal that PsA is a distinct joint disorder from RA. However, early diagnosis of PsA is difficult. The book illustrates how to accurately diagnose the disease through a systematic approach to PsA. It presents typical and important case studies, alongside rarer and interesting examples. It will be of interest to rheumatologists, dermatologists, orthopedists, radiologist, physiatrists, pediatricians, general physicians, and patients and their families.

Download or read book Psoriasis written by Hermenio Lima and published by BoD – Books on Demand. This book was released on 2013-04-17 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: By virtue of the dynamic nature of the scientific process, the description of the type, pathogenesis and treatment of a disease is always a work in progress. The complex nature of any disease can similarly be unveiled through understanding the historical context of our current understanding, examining prevailing hypotheses, and extrapolating horizons for new research. For better development of this book, the main objective was to provide insights on the types, causes, and treatments of psoriasis. This approach might substantially improve the transference of disease knowledge for physicians and intended to improve quality of medical services that endorses training of excellence and assesses the quali?cations of physicians, most of whom will be naive to clinical dermatological practices.

Download or read book Immune Markers in Psoriasis written by Carolina Constantin and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psoriasis is a chronic inflammatory skin disorder with high immunological background caused by a complex interplay between an altered immune system, genetic factors, autoantigens, lifestyle, and environmental factors. Extensive literature in recent years highlighted the crucial role played by the immune system in the pathogenesis of this pathology. Although it is unequivocally accepted that psoriasis is a T-cell mediated autoimmune condition, both innate and specific immune cells are highly involved in the pathogenesis of psoriasis. The aberrant interactions between immune cells and resident hyper-proliferative keratinocytes are mediated by immune and non-immune related molecules which lead to amplification of the local immune responses, that maintain the chronic inflammatory status. In this chapter, we will highlight the immune molecules resident in the psoriatic tissue or appending to the blood circulation that can indicate the prognosis of this systemic autoimmune disease. Moreover, we will focus on immune cells resident or circulating ones that can pinpoint the clinical evolution of the psoriatic disease. All these data can be developed in immune markers patterns that aid psoriasis diagnosis and/or future (immune)therapies.

Download or read book Moderate to Severe Psoriasis Fourth Edition written by John Y. M. Koo and published by CRC Press. This book was released on 2014-03-18 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in the dermatology field, this new fourth edition of Moderate-to-Severe Psoriasis discusses the current use of biologics and other pharmacologic and phototherapy treatments for moderate-to-severe psoriasis. Illustrated with high quality color figures, this standalone text emphasizes safe and effective treatments for the psoriasis patient that are perfect for the dermatologist in daily practice. New to this edition are chapters on day treatment programs, new agents, erythrodermic and pustular psoriasis, special populations, and pharmacogenetics.

Download or read book Psoriasis written by Jose O' Daly and published by BoD – Books on Demand. This book was released on 2012-03-16 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to present a comprehensive analysis of Psoriasis, a disease that affects approximately 2-3% of humanity in all countries. Psoriasis existence is surveyed since the clay tablets of Assyrians and Babylonians 3.000-5.000 years ago, thru the middle ages, the renaissance, XIX and XX centuries.

Download or read book Mosaic of Autoimmunity written by Carlo Perricone and published by Academic Press. This book was released on 2019-02-15 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis. Highlights the concept of the mosaic of autoimmune manifestations Includes new visions on unsuspected molecules Provides updated knowledge to physicians helping patients with autoimmune diseases Presents thorough, up-to-date information on specific diseases, along with clinical applications