Download or read book Immunology Of Nude Mice written by Miroslav Holub and published by CRC Press. This book was released on 2020-03-25 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1989, Immunology of Nude Mice presents a discussion of the nature of this viable laboratory mutant. This new volume updates all immunological information contained in the sparse literature concerning nude mice. It comprehensively explores some of the fre-quent questions associated with nude mice, such as if the mutant is really athymic or if the thymic defect causes all of the other deviations from brain to gonads. The practical consequences of hairlessness of the mutant are also consid-ered. Illustrated with original photographs and tables doc-umenting novel facts in immunology and physiology of nude mice, this publication is valuable for investigators and stu-dents entering the field.
Download or read book The Potentialities and Limitations of the Nude Mouse written by Tatsuji Nomura and published by Fischer Gustav Verlag GmbH & Company KG. This book was released on 1977 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Nude Mouse in Experimental and Clinical Research written by Jorgen Fogh and published by Elsevier. This book was released on 2014-01-01 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nude Mouse in Experimental and Clinical Research presents the state of knowledge regarding the nude mouse and its applications to different branches of scientific research. The research studies featured in this book emphasize the academic status of a broad range of subjects and techniques of nude mouse research. The text consists of 21 chapters, each discussing an important aspect of nude mouse research. Some chapters discuss the biological aspect such as physiology, genes, and breeding and mass production of the mouse. A number of the chapters also discuss the general observations of the mouse like histopathological observations and their background. The applications of the nude mouse to human tumor and cancer cell research are likewise given emphasis. This book will be of valuable importance to both students and researchers in the fields of medicine, biology, and pathology.
Download or read book The Nude Mouse in Oncology Research written by Epie Boven and published by CRC Press. This book was released on 2018-01-18 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nude, athymic mouse (nu/nu) has become generally accepted as a valuable tool to study the biology and therapy of human cancers. This volume presents a critical review of the scientific merits of the animal as a recipient of human tumor tissue transplants. Important information is provided regarding biology, immunology, and measures for genetic and microbiological control of the nude mouse. The discussion of transplantation sites and transplantability of human tumor tissue to the animals includes both the description of host factors and the tumor type involved. The characterization and monitoring of xenografts is followed by a review on their possible application for studies in tumor biology, such as hormones, growth factors, drug resistance, tumor markers, and heterogeneity. Experimental therapy is dedicated to cytostatic agents, hormones, monoclonal antibodies, cytokines, differentiation inducers and radiotherapy. The book also provides critical remarks regarding the limitation of the nude-mouse tumor models. The Nude Mouse in Oncology Research will provide essential reference information for oncology researchers, researchers who work with the nude mouse on a regular basis, and pharmaceutical companies.
Download or read book The Nude Mouse in Experimental and Clinical Research written by Jørgen Fogh and published by . This book was released on 1978 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nude Mice in Immunology written by Berenice Kindred and published by . This book was released on 1979 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bibliography of the Nude Mouse written by Jørgen Rygaard and published by . This book was released on 1977 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: 443 numbered references to literature (mostly journal articles). "Bibliography is based on the questionnaire sent out by the Nude Mouse Secretariat in the autumn of 1975. To this is added references collected elsewhere." Alphabetical arrangement by primary authors. Entries include bibliographical information. Subject index.
Download or read book The Potentialities and Limitations of the Nude Mouse written by and published by . This book was released on 1977 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Proceedings of the Third International Workshop on Nude Mice written by International Workshop on Nude Mice and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Proceedings of the Third International Workshop on Nude Mice Montana State University Bozeman Montana September 6 9 1979 Invited lectures infection and immunology written by Norman D. Reed and published by Fischer Gustav Verlag GmbH & Company KG. This book was released on 1982 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Humanized Mice written by Tatsuji Nomura and published by Springer Science & Business Media. This book was released on 2008-03-11 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term humanized mouse in this text refers to a mouse in which human tissues and cells have been transplanted and show the same biological function as they do in the human body. That is, the physiological properties and functions of tra- planted human tissues and cells can be analyzed in the mouse instead of using a living human body. It should therefore be possible to study the pathophysiology and treatment of human diseases in mice with good reproducibility. Thus, the hum- ized mouse can be used as a potent tool in both basic and clinical research in the future. The development of appropriate immunodeficient mice has been indispensable in the creation of the humanized mouse, which has been achieved through many years of efforts by several laboratories. The first stage on the road to the humanized mouse was the report on nude mice by Isaacson and Cattanach in 1962. Thereafter, nude mice were studied in detail by Falanagan and, in 1968, Pantelouris found that these mice have no thymus gland, which suggested that the mice lack transplan- tion immunity against xenografts such as human hematopoietic stem cells. At the Nude Mouse Workshops (organized by Regard, Povlsen, Nomura and colleagues) that were held nine times between 1972 and 1997, the possibility of creating a humanized mouse using nude mice was extensively examined. The results, however, showed that certain human cancers can be engrafted in nude mice, but unfortunately engraftment of normal human tissue was almost impossible.
Download or read book The Athymic Nude Rat written by Hans Petter Hougen and published by . This book was released on 1991 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Immune Response of Congenitally Athymic nude Mice to Xenografts of a Human Prostatic Cell Line written by Dean W. Roberts and published by . This book was released on 1975 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immune deficient Animals written by Bernard Sordat and published by S. Karger AG (Switzerland). This book was released on 1984 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The BALB c Mouse written by Michael Potter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mouse was first used in immunological research by Paul Ehrlich in 1891 in an extraordinary series of experiments on the maternal transfer of antitoxic immunity. A short 22 years later in 1913 Halsey Bagg acquired a stock of albino mice from a commercial dealer and used them in a series of experiments on learning. Because he was interested in the genetics of intelligence, Halsey Bagg began breeding a pedigreed line of these mice that were subsequently named for him - Bagg Albino. Though Halsey Bagg is not credited with initiating the inbred strains of mice, his stock curiously has played an indisputably important role. Bagg Albinos were progenitors of the present day BALB/c family of sublines - the subject of this book. They were also used as one of the parents in the development of inbred strains A, CBA and C3H, three other very famous strains. Today the BALB/c mouse is among the five most widely used inbred strains in biomedical research and a particular favorite in immunology and infectious disease research. The hallmark of the BALB/c response to so many kinds of infections is susceptibility and sometimes an exaggerated susceptibility, but this paradoxically is not associated with immunodeficiency as BALB/c is an excellent responder to immuni zation. These characteristics have made the BALB/c mouse a model for identifying genes that determine susceptibility to infectious and neoplastic diseases. In 1985 the laboratory BALB/c mouse became 72 years old. The current filial generations are somewhere around 350 generations [MURPHY].
Download or read book The Nude Mouse in Oncology Research written by Epie Boven and published by CRC Press. This book was released on 1991-10-07 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nude, athymic mouse (nu/nu) has become generally accepted as a valuable tool to study the biology and therapy of human cancers. This volume presents a critical review of the scientific merits of the animal as a recipient of human tumor tissue transplants. Important information is provided regarding biology, immunology, and measures for genetic and microbiological control of the nude mouse. The discussion of transplantation sites and transplantability of human tumor tissue to the animals includes both the description of host factors and the tumor type involved. The characterization and monitoring of xenografts is followed by a review on their possible application for studies in tumor biology, such as hormones, growth factors, drug resistance, tumor markers, and heterogeneity. Experimental therapy is dedicated to cytostatic agents, hormones, monoclonal antibodies, cytokines, differentiation inducers and radiotherapy. The book also provides critical remarks regarding the limitation of the nude-mouse tumor models. The Nude Mouse in Oncology Research will provide essential reference information for oncology researchers, researchers who work with the nude mouse on a regular basis, and pharmaceutical companies.
Download or read book Proceedings of the 3 International Workshop on Nude Mice Montana State University Bozeman Montana September 6 9 1979 written by Norman David Reed and published by . This book was released on 1982 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt:
