Download or read book Immunology 1930 1980 written by Pauline M. H. Mazumdar and published by . This book was released on 1989 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Historical Perspective on Evidence Based Immunology written by Edward J. Moticka and published by Newnes. This book was released on 2015-11-25 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology Presents concepts such as the division of lymphocytes into functionally different populations in their historical context Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells
Download or read book A Text Book of Immunology written by J.K. Sinha & S. Bhattacharya and published by Academic Publishers. This book was released on with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A History of Transplantation Immunology written by Leslie Brent and published by Academic Press. This book was released on 1996-11-18 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Those entering the field of transplantation are frequently unaware of the topics historical roots and even of the background on which modern discoveries in tolerance, histocompabatibility antigens, and xenotransplantation are based. A History of Transplantation Immunology is an account, written by one of the founding fathers of the field, of how tissue and organ transplantation has become one of the most successful branches of late 20th century medicine. The book helps place the work of contemporary scientists into its proper context and makes fascinating reading for immunologists in all stages of their career. Describes landmarks in immunology and places them in historical context Beautifully written by one of the founding fathers of the field Portrays the surprising history of events in a colorful and readable manner Contains biographical sketches of some of the pioneers Illustrates the development of key ideas in immunology--tolerance, graft rejection, and transplantation Foreword by Ray Owen
Download or read book The Age of Immunology written by A. David Napier and published by University of Chicago Press. This book was released on 2010-12-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this fascinating and inventive work, A. David Napier argues that the central assumption of immunology—that we survive through the recognition and elimination of non-self—has become a defining concept of the modern age. Tracing this immunological understanding of self and other through an incredibly diverse array of venues, from medical research to legal and military strategies and the electronic revolution, Napier shows how this defensive way of looking at the world not only destroys diversity but also eliminates the possibility of truly engaging difference, thereby impoverishing our culture and foreclosing tremendous opportunities for personal growth. To illustrate these destructive consequences, Napier likens the current craze for embracing diversity and the use of politically correct speech to a cultural potluck to which we each bring different dishes, but at which no one can eat unless they abide by the same rules. Similarly, loaning money to developing nations serves as a tool both to make the peoples in those nations more like us and to maintain them in the nonthreatening status of distant dependents. To break free of the resulting downward spiral of homogenization and self-focus, Napier suggests that we instead adopt a new defining concept based on embryology, in which development and self-growth take place through a process of incorporation and transformation. In this effort he suggests that we have much to learn from non-Western peoples, such as the Balinese, whose ritual practices require them to take on the considerable risk of injecting into their selves the potential dangers of otherness—and in so doing ultimately strengthen themselves as well as their society. The Age of Immunology, with its combination of philosophy, history, and cultural inquiry, will be seen as a manifesto for a new age and a new way of thinking about the world and our place in it.
Download or read book Networks of Innovation written by Louis Galambos and published by Cambridge University Press. This book was released on 1995 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Networks of Innovation offers a historical perspective on the manner in which private sector organizations have acquired, sustained, and periodically lost the ability to develop, manufacture, and market new serum antitoxins and vaccines. The primary focus is on the H. K. Mulford Company, on Sharp & Dohme, which acquired Mulford in 1929, and on Merck & Co., Inc., which merged with Sharp & Dohme in 1953. By surveying a century of innovation in biologicals, the authors show how the activities of these three commercial enterprises were related to a series of complex, evolving networks of scientific, governmental, and medical institutions in the United States and abroad.
Download or read book Instituting Science written by Timothy Lenoir and published by Stanford University Press. This book was released on 1997 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early practitioners of the social studies of science turned their attention away from questions of institutionalization, which had tended to emphasize macrolevel explanations, and attended instead to microstudies of laboratory practice. Though sympathetic to this approach--as the microstudies included in this book attest--the author is interested in re-investigating certain aspects of institution formation, notably the formation of scientific, medical, and engineering disciplines. He emphasizes the manner in which science as cultural practice is imbricated with other forms of social, political, and even aesthetic practices. This book offers case studies that reexamine certain critical junctures in the traditional historical picture of the evolution of the role of the scientist in modern Western society. It focuses especially on the establishment of new disciplines within German research universities in the nineteenth century, the problematic relationship that emerged between science, industry, and the state at the turn of the twentieth century, and post-World War II developments in science and technology. After an Introduction and two chapters dealing with science and technology as cultural production and the struggles of disciplines to achieve legitimation and authority, the author considers the following topics: the organic physics of 1847; the innovative research program of Carl Ludwig as a model for institutionalizing science-based medicine; optics, painting, and ideology in Germany, 1845-95; Paul Ehrlich's "magic bullet"; the Haber-Bosch synthesis of ammonia; and the introduction of nuclear magnetic resonance instrumentation into the practice of organic chemistry.
Download or read book The Immune Self written by Alfred I. Tauber and published by Cambridge University Press. This book was released on 1994 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immune Self is the first extended philosophical critique of immunology.
Download or read book Tomorrow s Cures Today written by Donald R Forsdyke and published by CRC Press. This book was released on 2003-09-02 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discussing the laws in the current research funding decision process, the author suggests ways to improve future funding of health research systems. Chapters recount ways of raising funds, the tragic way authorities improperly introduced diptheria immunization, consideration of how the peer review system evolved in response to massive infusion of funds in the nineteen forties, and the status quo generating a climate conducive to ethics violations, among others. This fascinating work will be an invaluable tool to researchers, health care workers, members of government agencies and those in charitable organizations that support health research, as well as to anyone interested in current trends in this area, including patients.
Download or read book AIDS in the UK written by Virginia Berridge and published by Oxford University Press. This book was released on 1996-03-28 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Fifteen years ago the AIDS `epidemic' did not exist on the public agenda. In just over a decade the public and official response to the disease has resulted in the development of a whole network of organizations devoted to the study, containment, and practical treatment of AIDS. In this important and original analysis of AIDS policy, Virginia Berridge examines the speed and nature of the official (and unofficial) response to this new and critical historical event. The policy reaction in Britain passed through three stages. From 1981-1986 the outbreak of a new contagious disease led to public alarm and social stigmatization, with a lack of scientific certainty about the nature of the disorder. AIDS was a new and open policy area - there were no established departmental, local, or health authority mechanisms for dealing with the problem. This was a period of policy development from below, with relatively little official action and many voluntary initiatives behind the scenes. This phase was succeeded in 1986-1987 by a brief stage of quasi-wartime emergency, in which national politicians and senior civil servants intervened, and a high-level political response emerged. The response was a liberal one of `safe sex' and harm minimization rather than draconian notification or isolation of carriers. The author demonstrates that despite the `Thatcher revolution'in government in the 1980s, crisis could still stimulate a consensual response. The current period of `normalization' of the disease sees panic levels subsiding as the rate of growth slows and the fear of the unknown recedes. Official institutions have been established and formal procedures adopted and reviewed; paid professionals have replaced the earlier volunteers. The 1990s have seen change in the liberal consensus towards a harsher response and the partial repoliticization of AIDS. In this fascinating and scholarly account, Virginia Berridge analyses a remarkable period in contemporary British history, and exposes the reaction of the British political and medical elites, and of the British public to one of the most challenging issues of this century.
Download or read book Intolerant Bodies written by Warwick Anderson and published by JHU Press. This book was released on 2014-11-15 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: A history of autoimmunity that validates the experience of patients while challenging assumptions about the distinction between the normal and the pathological. Winner of the NSW Premier's History Award of the Arts NSW Autoimmune diseases, which affect 5 to 10 percent of the population, are as unpredictable in their course as they are paradoxical in their cause. They produce persistent suffering as they follow a drawn-out, often lifelong, pattern of remission and recurrence. Multiple sclerosis, lupus, rheumatoid arthritis, and type 1 diabetes—the diseases considered in this book—are but a handful of the conditions that can develop when the immune system goes awry. Intolerant Bodies is a unique collaboration between Ian Mackay, one of the prominent founders of clinical immunology, and Warwick Anderson, a leading historian of twentieth-century biomedical science. The authors narrate the changing scientific understanding of the cause of autoimmunity and explore the significance of having a disease in which one’s body turns on itself. The book unfolds as a biography of a relatively new concept of pathogenesis, one that was accepted only in the 1950s. In their description of the onset, symptoms, and course of autoimmune diseases, Anderson and Mackay quote from the writings of Charles Dickens, Edgar Allan Poe, Joseph Heller, Flannery O’Connor, and other famous people who commented on or grappled with autoimmune disease. The authors also assess the work of the dedicated researchers and physicians who have struggled to understand the mysteries of autoimmunity. Connecting laboratory research, clinical medicine, social theory, and lived experience, Intolerant Bodies reveals how doctors and patients have come to terms, often reluctantly, with this novel and puzzling mechanism of disease causation.
Download or read book Vaccine Anxieties written by James Fairhead and published by Taylor & Francis. This book was released on 2012-04-27 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores how parents understand and engage with childhood vaccination in contrasting global contexts. This rapidly advancing and universal technology has sparked dramatic controversy, whether over MMR in the UK or oral polio vaccines in Nigeria. Combining a fresh anthropological perspective with detailed field research, the book examines anxieties emerging as highly globalized vaccine technologies and technocracies encounter the deeply intimate personal and social worlds of parenting and childcare, and how these are part of transforming science-society relations. It retheorizes anxieties about technologies, integrating bodily, social and wider political dimensions, and challenges common views of ignorance, risk, trust and rumour - and related dichotomies between Northernrisk society and Southerndeveloping society - that dominate current scientific and policy debates. In so doing, the book reflects critically on the stereotypes that at times pass forexplanations of public engagement with both routine vaccination and vaccine research. It suggests routes to improved dialogue between health professionals and the people they serve, and new ways to address science-society relations in a globalized world.
Download or read book Paul Ehrlich s Receptor Immunology written by Arthur M. Silverstein and published by Elsevier. This book was released on 2001-11-17 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paul Ehrlich's Receptor Immunology: The Magnificent Obsession describes the background to Paul Ehrlich's immunological works and theories and delves into the substance of his experiments in great detail. By exploring these early developments in immunology, the book lays the foundation for modern concepts, providing immunologists, biomedical researchers, and students the context for the discoveries in their field. The selectionist theory of antibody formation Kinetics of primary and secondary antibody response Quantitative methods of measurement of antigens and antibody Demonstration of passive transfer of immunity from mother to foetus
Download or read book A History of the Royal College of Physicians of London written by Sir George Norman Clark and published by Oxford University Press. This book was released on 1964 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 4 examines the way in which the Royal College of Physicians has adapted to far-reaching changes in medical knowledge, social attitudes and the organization of health. At the same time it illuminates the history of the NHS and examines controversial public issues such as smoking.
Download or read book Species and Specificity written by Pauline M. H. Mazumdar and published by Cambridge University Press. This book was released on 2002-07-18 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: An account of scientific disputes over the core problems of research and practice in immunology.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1991 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Allergy written by Mark Jackson and published by Reaktion Books. This book was released on 2007-08-15 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: It attacks through foods, animals, and innumerable chemical combinations. It is among the most common and potentially lethal afflictions known. It is the allergy, the subject of Mark Jackson’s fascinating chronicle. Jacksoninvestigates how the allergy became the archetypal “disease of civilization,” as it transformed from a fringe malady of the wealthy into one of the greatest medical disorders of the twentieth century. Jackson also examines the social and economic impact of the allergy, as it catalyzed a new health-conscious culture and created the wealth of some of the largest companies in the world today. Whether cats, crabgrass, or cheese is the source of your daily misery, Jackson’s engaging and in-depth account is an invaluable addition to every bookshelf.
