Download or read book Immunological Aspects of Gastroenterology written by Y.R. Mahida and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diseases of the gastrointestinal tract are common. There is increasing appreciation of the importance of the immune system in the pathogenesis of a number of these diseases. This book covers basic aspects of innate and adaptive immunity in the gastrointestinal tract, oral tolerance, and cellular and molecular mechanisms of acute and chronic inflammation. Specific disease covered include bacterial infections, human immunodeficiency virus (HIV) infection, coeliac disease, and inflammatory bowel disease. Other topics include mucosal immunisation and intestinal transplantation immunology. The readership of this book includes clinicians, scientists, and students interested in the gastrointestinal tract.
Download or read book Immunological Aspects of the Liver and Gastrointestinal Tract written by A. Ferguson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have been privileged to start our academic careers at the begin ning of the decade in which the immunological roles and hypersensitivity diseases of the gastrointestinal tract and liver have been defined. In the early 1960s IgA was reported to be the main secretory immunoglobulin, immunoblasts were shown to home to the intestinal mucosa and certain serum autoantibodies were described in patients with chronic liver disease. Shortly thereafter IgE and Australia antigen were discovered. Parallel advances in clinical investigation, in particular closed biopsy techniques, facilitated correlation of morphological changes with im munological mechanisms in disease of the gastrointestinal tract and liver. Only 10 years later, the concepts of immunity and hypersensitivity are regularly applied to the pathogenesis, diagnosis, treatment and prog nosis of many chronic diseases in these organs. In designing this book we have attempted to integrate theorectical and clinical immunology as they pertain in 1975; our ultimate aim is aptly described by Brachet as quoted by Professor Paronetto (page 319). We would like to think that this review provides a basis for the next major advances in the fields of gastrointestinal and hepatic immunology. As we see it, the outstanding problem in both sites is how to produce protective immunity without hypersensitivity.
Download or read book Immunology of Gastrointestinal Disease written by T.T. Macdonald and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal diseases present a considerable problem in human medicine in terms of both morbidity and mortality. The aim of this book is to cover the different immunological disorders of the gut with special reference to immunopathological and protective mechanisms. It will be of general interest to clinicians, scientists and students concerned with the gastrointestinal tract. Topics covered include: the current status of research into toxin-secreting pathogens, Campylobacter, Giardia and HIV; the immunological features of idiopathic inflammatory gut diseases such as Crohn's disease and intractable diarrhoea; the genesis of the flat mucosa; the iatrogenic diseases of the gut such as graft-versus-host disease and small bowel allografts; the immune mechanisms and lesions in the gut of patients with parasitic nematode infections (very important in the tropics). Basic background on the immune apparatus in the intestine is also discussed, as are the effects of inflammation on intestinal permeability.
Download or read book Immunological Aspects of Gastroenterology Surgical anatomy of the genitourinary system written by Y. R. Mahida and published by . This book was released on 2001 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunological Aspects of Liver Disease written by H.C. Thomas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Howard C. Thomas In normal subjects the regulatory apparatus of the immune system permits responses to foreign antigens but suppresses those directed to "self' components. Autoimmune disease occurs as a failure ofthis system either as a result of a primary defect in the regulatory apparatus (primary autoimmunization) or because of a change in the antigenicity of the tissues (secondary autoimmunization). Autoaggressive reactions are characterised by the presence of autoantibodies. When these are directed to membrane displayed antigens (Fig. 1) they are probably of importance in the lysis of hepatocytes. Those directed to cytoplasmic antigens may be useful diagnostically but are of unknown pathogenic significance. When no extrinsic aetiological factor can be identified, the process is assumed to be the result of a failure ofthe regulatory system, allowing the spontaneous expansion of a clone of autoreactive lymphocytes. The defect may be generalised or specific to certain groups of self-antigens and thus the autoimmune disease may be either multi- or unisystemic. The recent development of techniques to enumerate and measure the functional activity of the suppressor lymphocytes which control the effector limbs of the immune system has enabled investigators to test whether the various purported autoimmune diseases do have as their basis a generalised defect in immunoregu lation. Assessment of antigen-specific immunoregulatory function is, however, not yet readily available. liver Membrane I Antigen (LIM) I Liver I HLA, A, B, C, Sensitisation to Specific -;::!IIIL. .
Download or read book Immunology of the Gastrointestinal Tract written by Peter Asquith and published by . This book was released on 1979 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunophysiology of the Gut written by W. Allan Walker and published by Academic Press. This book was released on 2013-10-22 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bristol-Myers Squibb/Mead Johnson Nutrition Symposia, Volume 11: Immunophysiology of the Gut represents a comprehensive and systematic coverage of the immunophysiology of the gut, compiling research that integrates the mucosal immune system and intestinal physiology. This book discusses the immunological regulation of epithelial function, fibroblastic sheath, pathways of arachidonic acid metabolism, and gastric response to mucosal anaphylaxis. The implications for inflammatory diarrhea, role of breast milk in neonatal host defense, and milk-borne peptide growth factors in human and bovine milk are also elaborated. This publication likewise covers the immunopathologic features of celiac disease, immune responses in protein-energy malnutrition, and bacterial translocation. This volume is suitable for experts and clinicians from the disciplines of mucosal immunology, intestinal physiology, and enteric neurophysiology.
Download or read book Neuro Immuno Gastroenterology written by Cris S. Constantinescu and published by Springer. This book was released on 2016-05-24 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses important issues regarding the interaction between the nervous system, the immune system, and the digestive system. Gut flora has a profound influence on the shaping of the immune response, not only in the gastrointestinal system but also in the nervous system. Fascinatingly, manipulation of intestinal immune responses can be used to modulate neurological disease. Conversely, the nervous system and the psyche have significant effects on the functioning of the gut and liver. After introductory chapters on the neurology, the immunology and microbiology of the gut, the effects of the gut immune system and gut flora and its manipulation on neurological disease are discussed, followed by molecular mimicry and immune tolerance in neuroimmune diseases. Additionally, several chapters deal with gastrointestinal manifestations of neurological diseases. Neuro-Immuno-Gastroenterology is aimed at neurologists, gastroenterologists, and immunologists.
Download or read book Ontogeny of the Immune System of the Gut written by Thomas T. MacDonald and published by CRC Press. This book was released on 1990-09-24 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book highlights studies on the development of the mucosal immune system in the human fetus, the factors important in the development of the various compartments of this system, and the mechanisms by which the human neonate protects itself against gut allergy and infection. Other topics include the development of the gut immune system in rodents and other veterinary species in which important areas such as the intestinal uptake of the maternal immunoglobulins have been characterized, as well as immunocompetence of the human fetus. The book provides essential reference material for immunologists, pediatricians, and other researchers interested in the features unique to the development of the gut immune system in utero and post-natally in different species.
Download or read book Immunology of the Gastrointestinal Tract and Liver written by Martin F. Heyworth and published by Lippincott Williams & Wilkins. This book was released on 1988 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunology of the GI Tract written by Luis Rodrigo and published by BoD – Books on Demand. This book was released on 2022-12-21 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: The intestine is the largest digestive organ in the human body and one of the largest organs in contact with the outside world. In addition to digesting food to facilitate the absorption of nutrients, it has a variety of other functions, including the transmission of information and regulation of the metabolism. Due to its unique structure, the intestine is constantly exposed to various antigens and microbes. To protect the body from pathogens, while also maintaining a stable environment, the human intestinal tract has evolved unique regional immune characteristics maintained by the mature intestinal mucosal immune system. This intricate system involves intestinal epithelial cells, and intestinal lymphoid tissue composed of Peyer’s patches, isolated lymphoid follicles, mesenteric lymph nodes, and so on. The congenital and adaptive immune mechanisms created by the unique structure, function, and microenvironment of the intestine differ from those of the central and peripheral immune organs forming the regional immunity of the intestine. Intestinal flora also plays an important role in maintaining intestinal homeostasis, altering the structure and function of the immune system, reshaping the immune microenvironment, and promoting interference with the development of specific diseases. In fact, the immune function of the intestinal region directly affects the development of many intestine-specific diseases. However, the integrity of this function depends on the expression of congenital genes and the regulation of the neuroendocrine system. The microenvironment created by intestinal flora and its products also affects the immunity of the intestinal region. In early life, appropriate intestinal colonization by specific microflora stimulates the maturation of the intestinal mucosa-associated lymphoid tissue. If the appropriate intestinal flora fails to form during this life stage, the function of the intestinal immune system becomes impaired, leading to increased incidence and/or morbidity of certain intestinal diseases, including ulcerative colitis, Crohn’s disease, and others.
Download or read book Immunological Diseases of Liver and Gut written by M. Lukás and published by Springer Science & Business Media. This book was released on 2004-06-30 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the proceedings of the Falk Symposium No. 135 held in Prague, Czech Republic, on September 12-13, 2003, and is dedicated to the important issue of immunological aspects of diseases of the liver and gut. Without any doubt, immunological pathways are among the most important and universal factors in the pathogenesis of all diseases. Their importance is also constantly increasing, because these principles have been adopted in clinical practice for both diagnostic and therapeutic procedures. Chapters by prominent experts will stimulate new ideas and set the scene for productive discussion on this topic.
Download or read book Immune Mechanisms in Inflammatory Bowel Disease written by Richard Blumberg and published by Springer Science & Business Media. This book was released on 2007-02-26 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Mechanisms in Inflammatory Bowel Disease is a highly, concise update of the most recent advances in the immunobiology, genetics and microbiology related to Inflammatory Bowel Disease. This book broadly treats the topics that lead to understanding of the pathogenesis of this disease in an organized, systematic approach.
Download or read book Gastrointestinal Immunity for the Clinician written by Roy Gerrard Shorter and published by Saunders. This book was released on 1985 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pediatric Gastroenterology written by D. Branski and published by S. Karger AG (Switzerland). This book was released on 1986-01-01 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunology and Immunopathology of the Liver and Gastrointestinal Tract written by Stephan R. Targan and published by Igaku-Shoin Medical Publishers. This book was released on 1990 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunology Gastrointestinal Tract written by Klara Miller and published by CRC Press. This book was released on 1987 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
