Download or read book Immune Memory and Vaccines Great Debates written by Shane Crotty and published by Perspectives Cshl. This book was released on 2018-01-31 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A subject collection from the Cold Spring Harbor perspectives in biology."
Download or read book Immunization Safety Review written by Institute of Medicine and published by National Academies Press. This book was released on 2003-11-26 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.
Download or read book Framework for Equitable Allocation of COVID 19 Vaccine written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-11-30 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the coronavirus disease 2019 (COVID-19) pandemic and the societal disruption it has brought, national governments and the international community have invested billions of dollars and immense amounts of human resources to develop a safe and effective vaccine in an unprecedented time frame. Vaccination against this novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), offers the possibility of significantly reducing severe morbidity and mortality and transmission when deployed alongside other public health strategies and improved therapies. Health equity is intertwined with the impact of COVID-19 and there are certain populations that are at increased risk of severe illness or death from COVID-19. In the United States and worldwide, the pandemic is having a disproportionate impact on people who are already disadvantaged by virtue of their race and ethnicity, age, health status, residence, occupation, socioeconomic condition, or other contributing factors. Framework for Equitable Allocation of COVID-19 Vaccine offers an overarching framework for vaccine allocation to assist policy makers in the domestic and global health communities. Built on widely accepted foundational principles and recognizing the distinctive characteristics of COVID-19, this report's recommendations address the commitments needed to implement equitable allocation policies for COVID-19 vaccine.
Download or read book Ahead of the Curve written by Shane Crotty and published by Univ of California Press. This book was released on 2003-06 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biography of one of America's most famous and important molecular biologists.
Download or read book Immunization Safety Review written by Institute of Medicine and published by National Academies Press. This book was released on 2001-12-29 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this report, the Immunization Safety Review committee examines the hypothesis of whether or not the use of vaccines containing the preservative thimerosal can cause neurodevelopmental disorders (NDDs), specifically autism, attention deficit/hyperactivity disorder (ADHD), and speech or language delay.
Download or read book The Price We Pay written by Marty Makary and published by Bloomsbury Publishing USA. This book was released on 2019-09-10 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: New York Times bestseller Business Book of the Year--Association of Business Journalists From the New York Times bestselling author comes an eye-opening, urgent look at America's broken health care system--and the people who are saving it--now with a new Afterword by the author. "A must-read for every American." --Steve Forbes, editor-in-chief, FORBES One in five Americans now has medical debt in collections and rising health care costs today threaten every small business in America. Dr. Makary, one of the nation's leading health care experts, travels across America and details why health care has become a bubble. Drawing from on-the-ground stories, his research, and his own experience, The Price We Pay paints a vivid picture of the business of medicine and its elusive money games in need of a serious shake-up. Dr. Makary shows how so much of health care spending goes to things that have nothing to do with health and what you can do about it. Dr. Makary challenges the medical establishment to remember medicine's noble heritage of caring for people when they are vulnerable. The Price We Pay offers a road map for everyday Americans and business leaders to get a better deal on their health care, and profiles the disruptors who are innovating medical care. The movement to restore medicine to its mission, Makary argues, is alive and well--a mission that can rebuild the public trust and save our country from the crushing cost of health care.
Download or read book Immune written by Philipp Dettmer and published by Random House. This book was released on 2021-11-02 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • A gorgeously illustrated deep dive into the immune system that will forever change how you think about your body, from the creator of the popular science YouTube channel Kurzgesagt—In a Nutshell “Through wonderful analogies and a genius for clarifying complex ideas, Immune is a truly brilliant introduction to the human body’s vast system for fighting infections and other threats.”—John Green, #1 New York Times bestselling author of The Fault in Our Stars You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. But most of us never really stop to ask: What even is our immune system? Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes readers on a journey through the fortress of the human body and its defenses. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you’ve been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body. Each chapter delves into an element of the immune system, including defenses like antibodies and inflammation as well as threats like bacteria, allergies, and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body’s defenses, how viruses work, and what goes on in your wounds when you cut yourself. Enlivened by engaging full-color graphics and immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects—immunology—into a gripping adventure through an astonishing alien landscape. Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.
Download or read book Micro and Nanotechnology in Vaccine Development written by Mariusz Skwarczynski and published by William Andrew. This book was released on 2016-09-20 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines
Download or read book The Panic Virus written by Seth Mnookin and published by Simon and Schuster. This book was released on 2012-01-03 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: A searing account of how vaccine opponents have used the media to spread their message of panic, despite no scientific evidence to support them.
Download or read book The Death of Expertise written by Tom Nichols and published by Oxford University Press. This book was released on 2017-02-01 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technology and increasing levels of education have exposed people to more information than ever before. These societal gains, however, have also helped fuel a surge in narcissistic and misguided intellectual egalitarianism that has crippled informed debates on any number of issues. Today, everyone knows everything: with only a quick trip through WebMD or Wikipedia, average citizens believe themselves to be on an equal intellectual footing with doctors and diplomats. All voices, even the most ridiculous, demand to be taken with equal seriousness, and any claim to the contrary is dismissed as undemocratic elitism. Tom Nichols' The Death of Expertise shows how this rejection of experts has occurred: the openness of the internet, the emergence of a customer satisfaction model in higher education, and the transformation of the news industry into a 24-hour entertainment machine, among other reasons. Paradoxically, the increasingly democratic dissemination of information, rather than producing an educated public, has instead created an army of ill-informed and angry citizens who denounce intellectual achievement. When ordinary citizens believe that no one knows more than anyone else, democratic institutions themselves are in danger of falling either to populism or to technocracy or, in the worst case, a combination of both. An update to the 2017breakout hit, the paperback edition of The Death of Expertise provides a new foreword to cover the alarming exacerbation of these trends in the aftermath of Donald Trump's election. Judging from events on the ground since it first published, The Death of Expertise issues a warning about the stability and survival of modern democracy in the Information Age that is even more important today.
Download or read book Immunoproteomics written by Kelly M. Fulton and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing current diverse approaches and techniques used to study the immunoproteome, Immunoproteomics: Methods and Protocols collects chapters from key researchers that deliver information to be used in diagnostics, disease progression, and vaccine correlates of protection analysis, to name but a few. This detailed volume includes techniques used for the study of the antibody targets of bacterial pathogens, viruses, and cancer, mass spectrometry-based approaches to characterize T-cell epitopes, chapters on detection and relative quantification of cytokines in serum, as well as in silico prediction of epitopes using sequence-based or modeling approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and thorough, Immunoproteomics: Methods and Protocols aids researchers in transferring these techniques to their own laboratories in addition to providing a reference to guide researchers toward appropriate techniques.
Download or read book Vaccines A Biography written by Andrew W. Artenstein and published by Springer Science & Business Media. This book was released on 2009-12-11 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why another book about vaccines? There are already a few extremely well-written medical textbooks that provide comprehensive, state-of-the-art technical reviews regarding vaccine science. Additionally, in the past decade alone, a number of engrossing, provocative books have been published on various related issues ra- ing from vaccines against specific diseases to vaccine safety and policy. Yet there remains a significant gap in the literature – the history of vaccines. Vaccines: A Biography seeks to fill a void in the extant literature by focusing on the history of vaccines and in so doing, recounts the social, cultural, and scientific history of vaccines; it places them within their natural, historical context. The book traces the lineage – the “biography” – of individual vaccines, originating with deeply rooted medical problems and evolving to an eventual conclusion. Nonetheless, these are not “biographies” in the traditional sense; they do not trace an individual’s growth and development. Instead, they follow an idea as it is conceived and dev- oped, through the contributions of many. These are epic stories of discovery, of risk-takers, of individuals advancing medical science, in the words of the famous physical scientist Isaac Newton, “by standing on the shoulders of giants. ” One grant reviewer described the book’s concept as “triumphalist”; although meant as an indictment, this is only partially inaccurate.
Download or read book Considerations for Viral Disease Eradication written by Institute of Medicine and published by National Academies Press. This book was released on 2002-08-18 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since smallpox eradication, the science of eradication has changed and with it, our definitions of what diseases are possible to eradicate. However, eradication must not beget complacency. As has been learned from past control or eradication attempts with a variety of viral diseases, from yellow fever to influenza, accidental or intentional reintroduction is a real threat-one that could strike anywhere and for which we need to be fully prepared. The criteria for assessing eradicability of polio, measles, and other viral infections have been debated extensively. With the elimination and eradication of several viral diseases on the horizon, issues surrounding the cessation of immunization activities become exceedingly important. In an effort to better understand the dynamics of disease eradication and post-immunization policies, the Institute of Medicine Forum on Emerging Infections hosted a two-day workshop (February 1-2, 2001) on The Consequences of Viral Disease Eradication. This book explores the principles underlying the biological challenges, medical interventions, the continuing research agenda, and operational considerations for post-immunization strategies for vaccine-preventable viral diseases, and highlights important efforts that may facilitate wise decision making.
Download or read book Judgment Misguided written by Jonathan Baron and published by Oxford University Press, USA. This book was released on 1998 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: People often follow intuitive principles of decision making, ranging from group loyalty to the belief that nature is benign. But instead of using these principles as rules of thumb, we often treat them as absolutes and ignore the consequences of following them blindly. In Judgment Misguided, Jonathan Baron explores our well-meant and deeply felt personal intuitions about what is right and wrong, and how they affect the public domain. Baron argues that when these intuitions are valued in their own right, rather than as a means to another end, they often prevent us from achieving the results we want. Focusing on cases where our intuitive principles take over public decision making, the book examines some of our most common intuitions and the ways they can be misused. According to Baron, we can avoid these problems by paying more attention to the effects of our decisions. Written in a accessible style, the book is filled with compelling case studies, such as abortion, nuclear power, immigration, and the decline of the Atlantic fishery, among others, which illustrate a range of intuitions and how they impede the public's best interests. Judgment Misguided will be important reading for those involved in public decision making, and researchers and students in psychology and the social sciences, as well as everyone looking for insight into the decisions that affect us all.
Download or read book Values and Vaccine Refusal written by Mark Navin and published by Routledge. This book was released on 2015-09-16 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parents in the US and other societies are increasingly refusing to vaccinate their children, even though popular anti-vaccine myths – e.g. ‘vaccines cause autism’ – have been debunked. This book explains the epistemic and moral failures that lead some parents to refuse to vaccinate their children. First, some parents have good reasons not to defer to the expertise of physicians, and to rely instead upon their own judgments about how to care for their children. Unfortunately, epistemic self-reliance systematically distorts beliefs in areas of inquiry in which expertise is required (like vaccine immunology). Second, vaccine refusers and mainstream medical authorities are often committed to different values surrounding health and safety. For example, while vaccine advocates stress that vaccines have low rates of serious complications, vaccine refusers often resist vaccination because it is ‘unnatural’ and because they view vaccine-preventable diseases as a ‘natural’ part of childhood. Finally, parents who refuse vaccines rightly resist the utilitarian moral arguments – ‘for the greater good’ – that vaccine advocates sometimes make. Unfortunately, vaccine refusers also sometimes embrace a pernicious hyper-individualism that sanctions free-riding on herd immunity and that cultivates indifference to the interpersonal and social harms that unvaccinated persons may cause.
Download or read book Immunization Safety Review written by Institute of Medicine and published by National Academies Press. This book was released on 2004-09-30 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eighth and final report of the Immunization Safety Review Committee examines the hypothesis that vaccines, specifically the measles-mumps-rubella (MMR) vaccine and thimerosal-containing vaccines, are causally associated with autism. The committee reviewed the extant published and unpublished epidemiological studies regarding causality and studies of potential biologic mechanisms by which these immunizations might cause autism. Immunization Safety Review: Vaccines and Autism finds that the body of epidemiological evidence favors rejection of a causal relationship between thimerosal-containing vaccines and autism. The book further finds that potential biological mechanisms for vaccine-induced autism that have been generated to date are only theoretical. It recommends a public health response that fully supports an array of vaccine safety activities and recommends that available funding for autism research be channeled to the most promising areas. The book makes additional recommendations regarding surveillance and epidemiological research, clinical studies, and communication related to these vaccine safety concerns.
Download or read book Angel of Death written by G. Williams and published by Springer. This book was released on 2010-05-17 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: The story of the rise and fall of smallpox, one of the most savage killers in the history of mankind, and the only disease ever to be successfully exterminated (30 years ago next year) by a public health campaign.
