Download or read book Imidazole Dipeptides written by Victor R Preedy and published by Royal Society of Chemistry. This book was released on 2015-08-03 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carnosine and anserine are two common histidine-derived dipeptides, also known as imidazole dipeptides, found in muscle and brain tissues of animals. Their dietary and nutritional significance lies in their antioxidant properties and a number of investigators are looking at other health benefits of the compounds. This volume surveys the current state of play in these and other areas of interest, including chemistry and biochemistry, immunology and cellular homeostasis. Chapters look in depth at some of the functions and effects in the body particularly with regard to exercise and fatigue, wound healing, cancer treatment and age-related diseases. Providing an up to date, interdisciplinary approach, this book is of great interest to researchers and professionals in chemistry, food science, nutrition, biochemistry, health sciences and sports sciences.
Download or read book Imidazole Dipeptides written by Glenys A. Jones and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The imidazole dipeptides (ImD); anserine (Ans), carnosine (Cam) and balenine, have been shown to be effective at functioning as H+ ion buffers, with Carn being particularly effective within the physiological pH range. Therefore ImD have been reported to be beneficial to athletes exercising at high intensities, where the activity results in the production and accumulation of H+ ions within skeletal muscle. It has also been hypothesised that these compounds may also be beneficial in reducing the morbidities related to ageing, such as Alzheimer's disease. Humans store ImD in the form of Carn and not as anserine or balenine. However, within the human body Carn production is limited by the ability to degrade uracil in the liver, with (3-alanine being the limiting factor. Therefore the content of the diet has a substantial Impact on the level of Carn within human skeletal muscle. This thesis aimed to investigate the variability in ImD with age and in subjects from different geographical locations. The effect of ageing on the muscle content of the ImD was demonstrated through the use of a murine model, where increased age was accompanied with a 45% decline in the ImD levels measured in the tibialis anterior of 60wk old senescence-accelerated male mice (Chapter 9). This is supported by further work (Chapter 14) whIch showed that elderly European subjects exhibited lower levels of carnosine in the vastus lateralis compared to younger European subjects (15.6mmol·kg-1 dm and 22.4mmol·kg-1 dm respectively). However, in Korean elderly subjects no decline was observed (21.5mmol·kg-1 dm), and this could potentially be explained by different dietary habits, with the elderly Korean subjects consuming larger amounts of proteinrich foods than their European counterparts. Analysis was made of the variation in the carnosine content of the vastus lateralis in subjects from differing geographical locations, and subsequently different cultural diets with varying meat contents, and showed that dietary intake of a diet habitually rich in the ImD could potentially 'over-ride' the decline seen with age in subjects who 'reduce' their meat intake. This is supported by the observation of significantly lower Carn levels in vegetarian subjects (p
Download or read book Understanding Biology Using Peptides written by Sylvie E. Blondelle and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents proceedings of the 19th American Peptide Symposium. It highlights many of the recent developments in peptide science, with a particular emphasis on how these advances are being applied to basic problems in biology and medicine. Specific topics covered include novel synthetic strategies, peptides in biological signaling, post-translational modifications of peptides and proteins, and peptide quaternary structure in material science and disease.
Download or read book Processing and Impact on Active Components in Food written by Victor R Preedy and published by Academic Press. This book was released on 2014-05-27 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: From beef to baked goods, fish to flour, antioxidants are added to preserve the shelf life of foods and ensure consumer acceptability. These production-added components may also contribute to the overall availability of essential nutrients for intake as well as the prevention of the development of unwelcome product characteristics such as off-flavours or colours. However, there are processes that reduce the amount of naturally occurring antioxidants and awareness of that potential is just as important for those in product research and development. There is a practical need to understand not only the physiological importance of antioxidants in terms of consumer health benefit, but how they may be damaged or enhanced through the processing and packaging phases. This book presents information key to understanding how antioxidants change during production of a wide variety of food products, with a focus toward how this understanding may be translated effectively to other foods as well. Addresses how the composition of food is altered, the analytical techniques used, and the applications to other foods Presents in-chapter summary points and other translational insights into concepts, techniques, findings and approaches to processing of other foods Explores advances in analytical and methodological science within each chapter
Download or read book Inborn Metabolic Diseases written by John Fernandes and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: This clinical book facilitates the diagnosis of metabolic diseases. Each disease-related chapter begins with a detailed description of the patient and the delineating symptoms necessary for establishing the diagnosis and differential diagnosis. The metabolic derangement is described in great detail and illustrated in a uniform way, thus affording clarification and better understanding of the treatment. The topics covered range from the clinical approach to metabolic diseases, emergency treatment, diagnostic procedures, and psychosocial care for the child and the family to specific discussions of new modes of treatment, including liver, bone marrow transplantation and somatic gene therapy.
Download or read book More Efficient Utilization of Fish and Fisheries Products written by M. Sakaguchi and published by Elsevier. This book was released on 2004-05-18 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This international symposium allowed many researchers and industrial representatives to meet and discuss a broad spectrum of information such as zero emission, resources availability, sustainable utilization of resources, bioactive and functional components in aquatic organisms, utilization of wastes, seafood quality, surimi technologies and processing and safety. The book aims: To provide a current record presented in the international symposium More Efficient Utilization of Fish and Fisheries Products, 7-10 October 2001, Kyoto, Japan; To provide a stimulus to researchers in this area to cross-fertilize ideas and demonstrate examples of success; To enhance values and returns to fisheries fields in national and international terms by providing descriptions of better techniques and methods for utilizing the catch, reducing waste, and providing valuable by-products.
Download or read book Drug Repurposing for Emerging Infectious Diseases and Cancer written by Ranbir Chander Sobti and published by Springer Nature. This book was released on 2023-02-07 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents drug repurposing strategies to combat infectious diseases and cancer. It discusses key experimental and in silico approaches for modern drug repositioning, including signature matching, molecular docking, genome-wide associated studies, and network-based approaches aided by artificial intelligence. Further, the book presents various computational and experimental strategies for better understanding disease mechanisms and identify repurposed drug candidates for personalized pharmacotherapy. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges. Towards the end, the book discusses challenges and limitations encountered in computational drug repositioning.
Download or read book Molecular Nutrition written by Vinood B. Patel and published by Academic Press. This book was released on 2019-08-24 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Nutrition: Vitamins presents the nutritional and molecular aspects of vitamins with a specific focus on vitamins A, B1 (thiamine), B2 (riboflavin), B# (niacin), B5 (pantothenic acid), B6, (pyridoxine), B7 (biotin), B9 (folate), B12 (colbamin), C, D, E, and K. As part of the Molecular Nutrition series, this book discusses introductory aspects and general coverage of vitamins and nutrition, the molecular biology of the cell, including signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis. Final sections cover genetic machinery and its function, transcriptional processes, homeostasis genes, cancer, gene expression, mutations, and more. Emerging fields of molecular biology and important discoveries related to diet and nutritional health are also covered, rounding out the book. Summarizes molecular nutrition in health as related to vitamins Includes material on signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis Presents transcriptional processes, homeostasis genes, cancer, gene expression, mutations, the sodium-dependent multivitamin transporter, p53, p21, microRNAs, one carbon metabolism, nucleic acids, DNA methylation and polymorphisms Addresses emerging fields of molecular biology and presents important discoveries related to diet and nutritional health Covers Vitamins A, B, C, D, E, and K Discusses their impact on health relating to cancer, diabetes, arthritis, and aging Includes key facts, a mini dictionary of terms, and summary points
Download or read book The Handbook of Operator Fatigue written by Gerald Matthews and published by CRC Press. This book was released on 2017-11-01 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fatigue is a recognized problem in many facets of the human enterprise. It is not confined to any one area of activity but enters all situations in which humans have to perform for extended intervals of time. Most problematic are the circumstances in which obligatory action is continuous and the results of failure are evidently serious or even catastrophic. Therefore, the modern media especially highlights fatigue-related failures in industries such as transportation, materials processing and healthcare. It can be, and indeed is, no coincidence that most of the spectacular failures in process control that have resulted in the world's largest industrial accidents have occurred in the small hours of the morning when the circadian rhythm is lowest and operator fatigue itself peaks. While there have been legislative efforts made at state, federal and international levels to regulate working hours of employees, the appropriate implementation of such legislation is still a long way off. The Handbook of Operator Fatigue provides a comprehensive account of the subject to serve as the definitive reference work for researchers, students and practitioners alike. The volume features 30 chapters written by experts from around the world to address each important facet of fatigue, including: the scale of the fatigue problem (Section I), the nature of fatigue (Section II), how to assess fatigue (Section III), the impact of fatigue on health (Section IV), fatigue in the workplace (Section V), the neurological basis of fatigue (VI), sleep disorders (VII), and the design of countermeasures to fatigue (VIII).
Download or read book Frontiers of Biology written by Neuberger, A. and published by . This book was released on 1975 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inborn Metabolic Diseases written by Jean-Marie Saudubray and published by Springer Science & Business Media. This book was released on 2011-11-16 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Being up to Date: Status Quo and Trends of Treatment For those involved in the identification and management of patients with inborn errors of metabolism, this book is now recognised as the standard textbook in this interdisciplinary field. It has proved to be indispensable for professionals in specialities ranging from pediatrics, neonatology, pathological biochemistry and genetics to neurology, internal medicine, nursing, dietetics and psychology. This 5th edition has been extensively revised and updated. What ́s new - Additional chapter focusing on inborn errors affecting adults, particularly the late neurological presentations - Numerous updates on diagnostic procedures and treatment - Newly discovered disorders. As with previous editions, the book opens with a section presenting the clinical approach to inborn metabolic diseases for those cases in which a diagnosis is being sought. This now includes a chapter on the clinical presentation of metabolic diseases in the older age range, using an analogous structure. If a particular diagnosis is already suspected, the reader may refer to the following sections of the book containing general chapters on diagnostic procedures and treatment, and on specific groups of disorders. As with earlier editions, the chapters have been written by authors who are internationally recognised experts on their subjects. They provide information in a clear, relevant and concise manner using a coherent structure.
Download or read book Oxidative Stress in Skeletal Muscle written by Reznick and published by Birkhäuser. This book was released on 2012-12-06 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skeletal muscle consumes significant amounts of oxygen, and its oxygen flux increases significantly under conditions of exercise and muscle contraction. This makes the muscle vulnerable to oxidative stress since concomitantly with the increase of oxygen flow there is an increase of free oxygen radicals which are a byproduct of muscle respiration. A number of studies in the last decade have documented the involvement of free oxygen radicals in exercising muscles. The consequences of muscle oxidative stress have resulted mainly in increased muscle protein oxidation, elevation of lipid peroxidation, and depletion of muscle antioxidants. The mechanisms of this oxidative stress are under extensive investigation in laboratories around the world and are topics of the chapters in this volume. This book is intended for professionals who are interested in muscle function, physiology, pathophysiology and well-being, such as therapists, trainers and medical professionals as well as for researchers in the field of muscle physiology.
Download or read book Advances in Food and Nutrition Research written by Fidel Toldra and published by Elsevier. This book was released on 2021-07-24 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Food and Nutrition Research, Volume 97 provides interesting chapters written by an international board of authors. The topics covered in this book include the problematics of bacteriophages in dairy plants and methods for their monitorization and control, the obtention of antioxidant and antimicrobial compounds from sustainable sources and their application in meat and seafood products, the challenges and opportunities for vibrational spectroscopy to measure composition, and functional properties of foods, the physiological activity of bioactive peptides obtained from meat and meat by-products, the use of plant and marine-based polysaccharides for nano-encapsulation and their applications in food industry, the effects of early life stress on eating behavior and metabolism considering different factors that control appetite, the nutritional aspects of seafood and its health benefits, the use of Colocasia esculenta (L.) Schott and Xanthosoma sagittifolium (L.) Schott powder as a valid option for the nutritional and technological improvement of food products, and much more. The series provides the latest advances on the identification and characterization of emerging bioactive compounds with putative health benefits, and other functional compounds of relevance in foods as well as up-to-date information on food science, including raw materials, production, processing, distribution and consumption. Contains contributions that have been carefully selected based on their vast experience and expertise on the subject Includes updated, in-depth and critical discussions of available information, giving the reader a unique opportunity to learn Encompasses a broad view of the topics at hand
Download or read book Alcohol in Health and Disease written by Dharam Agarwal and published by CRC Press. This book was released on 2001-06-01 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, based on presentations from the symposium on the health effects of alcohol held in Titisee, Germany, examines the physical and psychological consequences of alcohol use and abuse, and considers environmental and ethnic factors that lead to addiction and dependence. Discusses epidemiological studies that show the influence of light to moderate intake of alcoholic beverages on coronary heart disease. Featuring contributions from nearly 60 internationally recognized and respected authors, and over 2900 references for further investigation of the subject, Alcohol in Health and Disease analyzes biochemical, pharmacogenetic, and pathologic disturbances that follow acute and chronic ingestion of alcohol; describes complications that arise from social, biological, and environmental factors; examines alcohol metabolic genes and their role in alcohol sensitivity, drinking habits, and dependence; spotlights hepatic and nutritional disorders associated with alcoholism; considers the relationship of alcohol to cancer; debates the French paradox and more. Covering a multitude of disciplines, including molecular biochemistry, genetics, epidemiology, pathophysiology, neurobiology, and cardiology, Alcohol in Health and Disease is a critical reference for addiction psychiatrists, neuropsychopharmacologists, psychologists, geneticists, toxicologists, biochemists, environmental and public health scientists, health policy makers, social workers, counselors, and graduate and medical school students in these disciplines.
Download or read book Capillary Electrophoresis in Food Analysis written by María Castro-Puyana and published by Bentham Science Publishers. This book was released on 2022-06-20 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference describes recent advances and applications of capillary electrophoresis in the field of food science. The first two chapters are devoted to the fundamentals of capillary electrophoresis, and to the main sample preparation techniques used for food analysis using this miniaturized separation technique, respectively. These two introductory chapters are followed by several chapters focused on the different strategies for analyzing specific food components, including lipids, carbohydrates, proteins, peptides, amino acids, vitamins, polyphenols, and food additives. The information provided in these chapters helps readers to understand and develop appropriate methods to carry out a deep characterization of food samples. Relevant concepts such as food authentication, chemical food safety or the control of the quality and safety of dietary supplements, and food metabolomics are also covered, where appropriate. The big potential of capillary electrophoresis to achieve chiral separations and the determination of enantiomers in food samples or to develop targeted and non-targeted metabolomics strategies to ensure food safety and quality is also described. As an additional step towards analytical miniaturization, a chapter devoted to food analysis by microchip electrophoresis is also included in this book. All 14 chapters are contributed by highly experienced researchers in the field. Capillary Electrophoresis in Food Analysis is a key source of information for food chemists and analytical chemists in industry (quality control laboratories) and academia (research labs and training courses).
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1982 with total page 1000 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Muscle Foods Analysis written by Leo M.L. Nollet and published by CRC Press. This book was released on 2008-11-10 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: In today's nutrition-conscious society, there is a growing awareness among meat scientists and consumers about the importance of the essential amino acids, vitamins, and minerals found in muscle foods. Handbook of Muscle Foods Analysis provides a comprehensive overview and description of the analytical techniques and application methodologies for t
