Download or read book Genomics in the Cloud written by Geraldine A. Van der Auwera and published by "O'Reilly Media, Inc.". This book was released on 2020-04-02 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data in the genomics field is booming. In just a few years, organizations such as the National Institutes of Health (NIH) will host 50+ petabytesâ??or over 50 million gigabytesâ??of genomic data, and theyâ??re turning to cloud infrastructure to make that data available to the research community. How do you adapt analysis tools and protocols to access and analyze that volume of data in the cloud? With this practical book, researchers will learn how to work with genomics algorithms using open source tools including the Genome Analysis Toolkit (GATK), Docker, WDL, and Terra. Geraldine Van der Auwera, longtime custodian of the GATK user community, and Brian Oâ??Connor of the UC Santa Cruz Genomics Institute, guide you through the process. Youâ??ll learn by working with real data and genomics algorithms from the field. This book covers: Essential genomics and computing technology background Basic cloud computing operations Getting started with GATK, plus three major GATK Best Practices pipelines Automating analysis with scripted workflows using WDL and Cromwell Scaling up workflow execution in the cloud, including parallelization and cost optimization Interactive analysis in the cloud using Jupyter notebooks Secure collaboration and computational reproducibility using Terra

Download or read book Process Centrifugal Compressors written by Klaus H. Lüdtke and published by Springer Science & Business Media. This book was released on 2004-02-09 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originating in the process compressor industry, this text primarily addresses: rotating equipment engineers, project engineers, engineering contractors, and compressor user companies in oil and gas field operations, natural gas processing, petroleum refining, petrochemical processing, industrial refrigeration, and chemical industries. It enables the reader to assess compressors and defines the constraints influencing the compressor design.

Download or read book Practical Guide to Life Science Databases written by Imad Abugessaisa and published by Springer Nature. This book was released on 2022-01-06 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the latest information of life science databases that center in the life science research and drive the development of the field. It introduces the fundamental principles, rationales and methodologies of creating and updating life science databases. The book brings together expertise and renowned researchers in the field of life science databases and brings their experience and tools at the fingertips of the researcher. The book takes bottom-up approach to explain the structure, content and the usability of life science database. Detailed explanation of the content, structure, query and data retrieval are discussed to provide practical use of life science database and to enable the reader to use database and provided tools in practice. The readers will learn the necessary knowledge about the untapped opportunities available in life science databases and how it could be used so as to advance basic research and applied research findings and transforming them to the benefit of human life. Chapter 2 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Download or read book NASA Technical Note written by and published by . This book was released on 1967 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in Thermofluids and Renewable Energy written by Pinakeswar Mahanta and published by Springer Nature. This book was released on 2021-10-21 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprises the select proceedings of the International Conference on Recent Trends in Developments of Thermofluids and Renewable Energy (TFRE 2020). The major topics covered include aerodynamics, alternate energy, bio fuel, bio heat transfer, computational fluid dynamics, control mechanism for constant power generation, and energy storage. The book also discusses latest developments in the fields of electric vehicles, hybrid power systems, and solar and renewable energy. Given the scope of its contents, this book will be useful for students, researchers, and professionals interested in the field of thermofluids and renewable energy resources.

Download or read book Plant Stress Tolerance written by Ramanjulu Sunkar and published by Springer Nature. This book was released on with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Compaction and cementation controls on reservoir quality in Buntsandstein red beds written by Schmidt, Christina and published by KIT Scientific Publishing. This book was released on 2022-05-02 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reservoir quality in fluvial siliciclastic rocks is variable. Permeability is influenced by micron-scale grain coatings or bedding style on the m-/km-scale. Outcrops allow the analysis of depositional environments and diagenesis, thus an investigation of reservoir quality controls. A process-oriented approach is used to understand variability in a meander deposit, compaction and cementation behavior of lithofacies types during burial and the discrepancy between porosity and permeability values.

Download or read book Molecular Approaches To Tumor Immunotherapy written by Yang Liu and published by World Scientific. This book was released on 1998-12-28 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: The articles in this book are contributed by leading scientists working in the fields of immunology, tumor immunotherapy, and gene therapy. The book identifies the opportunities that modern immunology and molecular biology have provided for tumor therapy. Moreover, it contains critical essays that analyze the progress and obstacles of tumor immunotherapy.

Download or read book Diagenetic controls on fluid flow and mechanical properties in Rotliegend reservoir sandstones written by Monsees, Alexander C. and published by KIT Scientific Publishing. This book was released on 2021-10-28 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reservoir quality of Rotliegend sandstones is mainly controlled by their permeability, and porosity, and their mechanical properties. Thus, diagenetic porosity-reducing processes need to be understood to evaluate reservoir quality and geotechnical properties in sandstones. Best reservoir qualities are achieved in mature sandstones with large amounts of quartz cementation. The relative length of grain-contacts compared to the respective grain diameter is identified as proxy for rock strength.

Download or read book Bioinformatics Data Skills written by Vince Buffalo and published by "O'Reilly Media, Inc.". This book was released on 2015-07 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn the data skills necessary for turning large sequencing datasets into reproducible and robust biological findings. With this practical guide, youâ??ll learn how to use freely available open source tools to extract meaning from large complex biological data sets. At no other point in human history has our ability to understand lifeâ??s complexities been so dependent on our skills to work with and analyze data. This intermediate-level book teaches the general computational and data skills you need to analyze biological data. If you have experience with a scripting language like Python, youâ??re ready to get started. Go from handling small problems with messy scripts to tackling large problems with clever methods and tools Process bioinformatics data with powerful Unix pipelines and data tools Learn how to use exploratory data analysis techniques in the R language Use efficient methods to work with genomic range data and range operations Work with common genomics data file formats like FASTA, FASTQ, SAM, and BAM Manage your bioinformatics project with the Git version control system Tackle tedious data processing tasks with with Bash scripts and Makefiles

Download or read book Chronic Lymphocytic Leukemia written by Federico Caligaris-Cappio and published by Springer Science & Business Media. This book was released on 2005-12-29 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of their ramifications within the fields of hematology, immunology and oncology. For a long time the Cinderella of lymphoid malignancies CLL has now become the focus of major interest and an increasing number of investigators from different areas, including genetics, molecular biology, basic and applied immunology are becoming actively engaged in the investigation of CLL. Clinicians are considering CLL as a very interesting target of many projects which aim at translating the new and exciting developments of basic science into effective new approaches to the patient.

Download or read book Introduction to the Characterization of Residual Stress by Neutron Diffraction written by M.T. Hutchings and published by CRC Press. This book was released on 2005-02-28 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 25 years the field of neutron diffraction for residual stress characterization has grown tremendously, and has matured from the stage of trial demonstrations to provide a practical tool with widespread applications in materials science and engineering. While the literature on the subject has grown commensurately, it has also remained

Download or read book Concepts in Turbocharging for Improved Efficiency and Emissions Reduction written by Mehrdad Zangeneh and published by SAE International. This book was released on 2014-09-22 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legislative requirements to reduce CO2 emissions by 2020 have resulted in significant efforts by car manufacturers to explore various methods of pollution abatement. One of the most effective ways found so far is by shortening the cylinder stroke and downsizing the engine. This new engine then needs to be boosted, or turbocharged, to create the full and original load torque. Turbocharging has been and will continue to be a key component to the new technologies that will make a positive difference in the next-generation engines of years to come. Concepts in Turbocharging for Improved Efficiency and Emissions Reduction explores the many ways that turbocharging will deliver concrete results in meeting the new realities of sustainable, green transportation. This collection of very focused technical papers, selected by Mehrdad Zangeneh, PhD., a professor of thermo-fluids at University College in London, provides an assessment of several novel designs intended to improve fuel consumption and cap emissions, while maintaining torque at all speeds. The book is divided into four sections, each addressing the most cutting-edge technologies on the market today: o Two-Stage Turbocharging o Variable Geometry Compressors o Unconventional Compressor Configurations o Electrically Assisted Turbocharging

Download or read book Unit Maintenance Manual written by and published by . This book was released on 1989 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book GI Emergencies written by Robert C. Lowe and published by SLACK Incorporated. This book was released on 2011 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Practical and evidence-based, GI Emergencies: A Quick Reference Guide from Dr. Robert C. Lowe and Dr. Francis A. Farraye outlines diagnosis and medical management of common gastrointestinal emergencies in a case-based format. The knowledge of seasoned gastroenterology practitioners combined with the common questions of trainees' folds perfectly together to create an enjoyable read for the learning physician with all the impact and educational value of a formally styled textbook. This dual-perspective approach of GI Emergencies: A Quick Reference Guide takes medical students through the workup and treatment of various clinical cases in a "real time" format. This pocket-sized handbook also includes key teaching points to assist physicians with interns, residents, and medical students in training, making it an all-around reference for those in the gastroenterology field"--Provided by publisher.

Download or read book Computer Safety Reliability and Security written by Rune Winther and published by Springer Science & Business Media. This book was released on 2005-09-19 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 24th International Conference on Computer Safety, Reliability, and Security, SAFECOMP 2005, held in Fredrikstad, Norway, in September 2005. The 30 revised full papers were carefully reviewed and selected for inclusion in the book. The papers address all aspects of dependability and survivability of critical computerized systems in various branches and infrastructures.

Download or read book Computer Programs for Chemistry written by DeLos DeTar and published by Elsevier. This book was released on 2012-12-02 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer Programs for Chemistry, Volume 4, aims to make available a useful collection of tested programs, which may be expected to have a long useful life. Since the programs in each volume are represented by considerably over 10,000 source cards, arrangements have been made to provide a master tape for each volume. The programs in the series fall into two broad classes: complete packages and subroutines. ANSI FORTRAN has been chosen as the language since it provides adequate flexibility and excellent compatibility. But where departures are needed for efficiency, the editors have not hesitated to allow use of small subroutines in nonstandard FORTRAN or in assembly language, with careful documentation. The programs discussed in this volume include LSKIN2, FRS3, GENLSS, CDORD, EQCENT, EDITQ and EDITID, LORAK, and INDEX. Anyone who intends to use computer techniques will have to learn about computer hardware and computer software. To use effectively even the stand-alone programs in these volumes requires some understanding of FORTRAN. This volume also contains a number of converting subroutines that are useful primarily to the serious programmer. These have proved especially useful as parts of programs presented in previous volumes.