Download or read book IFM 99 written by Keijiro Araki and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Formal methods have been established as the rigorous engineering methodology for the system development. Applying formal methods to a large and complex system development often requires the modelling of different aspects of such a system. For instance, complex systems (such as integrated avionics systems, engine control software) can involve functional and timing requirements that must be eventually implemented as executing code on a communicating distributed topology. This book contains the papers presented at the First International Workshop on Integrated Formal Methods, held at the University of York in June 1999. The conference provided a forum for the discussion of theoretical aspects of combing behavioural and state-based formalisms and practical solutions to the industrial problems of this approach.
Download or read book Thomas Hematopoietic Cell Transplantation 2 Volume Set written by Stephen J. Forman and published by John Wiley & Sons. This book was released on 2016-12-27 with total page 1789 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.
Download or read book Thomas Hematopoietic Cell Transplantation written by Stephen J. Forman and published by John Wiley & Sons. This book was released on 2015-12-14 with total page 1416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.
Download or read book Immunomodulating Drugs for the Treatment of Cancer written by Asher A.A. Chanan-Khan and published by Lippincott Williams & Wilkins. This book was released on 2012-03-29 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunomodulating Drugs for the Treatment of Cancer provides a comprehensive resource for clinicians and researchers regarding immunomodulatory (IMiDs) drugs and their rapidly emerging role in cancer medicine. This new class of anticancer agents has made a tremendous impact on the treatment of patients with various malignant diseases, including blood cancers and several cancers of the solid organs. Their popularity in prescribing is based on several important characteristics including: (1) oral bioavailability, (2) non-chemotherapeutic, (3) extremely well-tolerated in all age groups, (4) ability to activate patient's own immune response against cancer, (5) ease of combination with other agents such as chemotherapy resulting in higher responses as well as (6) variability of anticancer activity.
Download or read book FM 99 Formal Methods written by Jeannette M. Wing and published by Springer. This book was released on 2003-07-31 with total page 955 pages. Available in PDF, EPUB and Kindle. Book excerpt: Formal methods are coming of age. Mathematical techniques and tools are now regarded as an important part of the development process in a wide range of industrial and governmental organisations. A transfer of technology into the mainstream of systems development is slowly, but surely, taking place. FM’99, the First World Congress on Formal Methods in the Development of Computing Systems, is a result, and a measure, of this new-found maturity. It brings an impressive array of industrial and applications-oriented papers that show how formal methods have been used to tackle real problems. These proceedings are a record of the technical symposium ofFM’99:alo- side the papers describingapplicationsofformalmethods,youwill ndtechnical reports,papers,andabstracts detailing new advances in formaltechniques,from mathematical foundations to practical tools. The World Congress is the successor to the four Formal Methods Europe Symposia, which in turn succeeded the four VDM Europe Symposia. This s- cession re?ects an increasing openness within the international community of researchers and practitioners: papers were submitted covering a wide variety of formal methods and application areas. The programmecommittee re?ects the Congress’s international nature, with a membership of 84 leading researchersfrom 38 di erent countries.The comm- tee was divided into 19 tracks, each with its own chair to oversee the reviewing process. Our collective task was a di cult one: there were 259 high-quality s- missions from 35 di erent countries.
Download or read book Integrated Formal Methods written by Michael Butler and published by Springer. This book was released on 2003-08-01 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third in a series of international conferences on Integrated Formal Methods, IFM 2002, was held in Turku, Finland, May 15–17, 2002. Turku, situated in the south western corner of the country, is the former capital of Finland. The ? conference was organized jointly by Abo Akademi University and Turku Centre for Computer Science. The theme of IFM 1999 was the integration of state and behavioral based formalisms. For IFM 2000 this was widened to include all aspects pertaining to the integration of formal methods and formal notations. One of the goals of IFM 2002 was to further investigate these themes. Moreover, IFM 2002 explored the relations between formal methods and graphical notations, especially the industrialstandardlanguageforsoftwaredesign,theUni?edModelingLanguage (UML). The themes of IFM 2002 re?ect what we believe is a growing trend in the Formal Methods and Software Engineering research communities. Over the last threedecades,computerscientistshavedevelopedarangeofformalismsfocusing on particular aspects of behavior or analysis, such as sequential program str- tures,concurrentprogramstructures,dataandinformationstructures,temporal reasoning, deductive proof, and model checking. Much e?ort is now being - voted to integrating these methods in order to combine their advantages and ensure they scale up to industrial needs. Graphical notations are now widely used in software engineering and there is growing recognition of the importance ofprovidingthesewiththeformalunderpinningsandformalanalysiscapabilities found in formal methods.
Download or read book Integrated Formal Methods written by Wolfgang Grieskamp and published by Springer Science & Business Media. This book was released on 2000-10-18 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the Second International Conference on Integrated Formal Methods, IFM 2000, held in Dagstuhl, Germany in November 2000. The 22 revised full papers presented together with the abstracts of two invited talks were carefully reviewed and selected from 58 submissions. The papers are grouped together in topical sections on linking and extending notations, methodology, foundation of one formalism by another, semantics, and verification and validation.
Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-13 with total page 8018 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Download or read book Multiple Myeloma New Insights for the Healthcare Professional 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Myeloma: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Multiple Myeloma: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Multiple Myeloma: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Myeloma Therapy written by Sagar Lonial and published by Springer Science & Business Media. This book was released on 2009-01-01 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic options for patients with myeloma have dramatically changed over the past 10 years. Beginning with the advances in therapy resulting from the use of high-dose therapy and autologous bone marrow or stem cell tra- plant, we have more than doubled the median survival for patients as a whole, and have now have a wealth of different biology -based treatment approaches for our patients in all disease stages. This book represents state-of-the-art information from many of the leaders in the plasma cell disorders world. Sections focusing on disease pathogenesis and biology, chemotherapy-based approaches, immune -based therapies, currently approved novel agents, developing targets, supportive care, and other plasma cell disorders provides a comprehensive collection and an excellent resource in this time of rapid change in clinical and preclinical disease knowledge. It is important to realize that these changes did not occur in a vacuum. Partnerships between academic institutions, the pharmaceutical industry, patient advocacy groups, the National Cancer Institute, community onco- gists, and ultimately our patients worked closely together to realize these advances, and to effect the radical changes in therapy we have witnessed over the past few years. This book would not have been possible without contri- tions from each of the gifted scientists and clinicians who worked tirelessly to prepare their individual chapters all the while maintaining commitment to the scientific and clinical mission of advancing care.
Download or read book Copulas and Their Applications in Water Resources Engineering written by Lan Zhang and published by Cambridge University Press. This book was released on 2019-01-10 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illustration of copula theory with detailed real-world case study examples in the fields of hydrology and water resources engineering.
Download or read book FME 2003 Formal Methods written by Keijiro Araki and published by Springer Science & Business Media. This book was released on 2003-08-27 with total page 955 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the International Symposium of Formal Methods Europe, FME 2003, held in Pisa, Italy in September 2003. The 44 revised full papers presented together with 5 invited papers were carefully reviewed and selected from 144 submissions. The papers are organized in topical sections on industrial issues, control systems and applications, communication system verfication, co-specification and compilers, composition, Java, object-orientation and modularity, model checking, parallel processes, program checking and testing, B method, and security.
Download or read book Devita Hellman and Rosenberg s Cancer written by Govindan and published by Lippincott Williams & Wilkins. This book was released on 2012 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on: DeVita, Hellman, and Rosenberg's cancer / editors, Vincent T. DeVita Jr., Theodore S. Lawrence, Steven A. Rosenberg. 9th ed. c2011.
Download or read book Contemporary Management of Multiple Myeloma written by Ravi Vij and published by JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.. This book was released on 2012-12-15 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book "Contemporary Management of Multiple Myeloma" discusses in detail about the management of multiple myeloma. Multiple Myeloma is the second most common hematological malignancy in the United States. This book highlights the interplay between the malignant plasma cell and the microenvironment, and the role of genetic alterations, adhesion molecules and critical cytokines in this complex milieu. The first chapter of this book discusses epidemiology, etiology and pathogenesis of multiple myeloma. The clinical presentation of the common plasma cell dyscrasias and discuss the diagnostic and prognostic work-up with a highlighting on recent advances in chapters 3 and 4. Chapters from 5 to 9 focus on the therapeutic evolution that has occurred, and accumulate the landmark clinical trials that have changed clinical practice for up-front treatment of both transplant eligible and ineligible patients and for those with relapsed and refractory disease. These chapters also highlights on the important role of clinical research with stem cell transplantation, proteasome-inhibition and immunomodulatory drugs that form the backbone of our present day therapeutic armamentarium. Recommendations for response assessment and current understanding of the value of maximizing the depth of response in personalized therapy and patient segmentation are briefly explained in chapters 10 and 11. Chapter 12 and 13 discussed about adjunctive treatment modalities and novel therapeutic compounds in clinical trial and targets for future drug development. This book provides complete information about current landscape for multiple myeloma which is helpful in future aspects.
Download or read book Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and published by Springer Science & Business Media. This book was released on 2010-03-02 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
Download or read book DeVita Hellman and Rosenberg s Cancer written by Ramaswamy Govindan and published by Lippincott Williams & Wilkins. This book was released on 2009 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on DeVita, Lawrence, and Rosenberg's Cancer: Principles & Practice of Oncology, Eighth Edition, this comprehensive question-and-answer review book covers the entire specialty of oncology and provides thorough preparation for oncology boards. The book contains hundreds of multiple-choice and case-based questions covering the principles of surgical oncology, radiation oncology, medical oncology, and hematology/oncology and the biology, diagnosis, staging, and multimodality treatment of cancers at every anatomic site. Included are state-of-the-art chapters on molecular techniques, targeted therapies, and current approaches to cancer prevention. Questions are followed by answers and detailed explanations. A companion Website will offer an interactive question bank for individual self-testing.
Download or read book Treatment of Multiple Myeloma and Related Disorders written by S. Vincent Rajkumar and published by Cambridge University Press. This book was released on 2008-10-27 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to major advances in understanding the biology and pathogenesis of the disease, the management of multiple myeloma is changing rapidly. New diagnostic and prognostic criteria have been introduced, and treatment options are multiplying with high-dose chemotherapy regimens, stem cell transplants, and the development of novel agents and immune-based strategies that target tumor cells directly. This book is aimed at the practitioner who is looking to put these advances into clinical context. It will serve as an up-to-date resource for treatment of myeloma and related disorders. Chapters are written by international authorities and contain color photos, diagrams, and algorithms outlining preferred treatment strategies. Relevant scientific information is integrated throughout, but the focus here is on providing practical therapeutic guidance for oncologists and hematologists caring for myeloma patients. The book covers all myeloma subtypes and related disorders, including amyloidosis, Waldenstrom macroglobulinemia, plasmacytoma, MGUS, and POEMS syndrome.
