Download or read book Identification of Cytotoxic T Cell Epitopes on Measles virus Nucleoprotein written by Eva Barbara Schadeck and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Identification of Cytotoxic T Cell Epitopes on Measles virus Protein written by Eva B. Schadeck and published by . This book was released on 1997 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Measles Virus written by Volker ter Meulen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Measles, also called the greatest killer of children in history, still annually affects about 50 million individuals and causes close to a million deaths primarily in developing countries. Before the advent of measles vaccine some 30 years ago, these figures were roughly three times higher. Attenuated measles virus (MV) strains, all quite closely related to the original Edmonston isolate, have a very good record as a safe and highly efficacious vaccine and have brought down the measles toll in industrialized countries to almost negligible levels. However, recent outbreaks in the USA and Europe have again brought the measles problem to public attention. Sadly enough, these outbreaks were more instrumental in inducing activities to drastically reduce and hopefully finally eradicate measles than were the ten thousand times higher number of victims in developing countries. To reach this goal, as detailed in this volume, apparently it is not enough to of the existing vaccine as was the rigorously enforce use case with smallpox eradication: the intricacies of measles disease phenomena, in particular the generalized immune suppression which favors secondary infections, require more basic knowledge of the virus-host interactions and probably the development of new vaccines for special applications such as first immunizations of very young infants in developing countries.
Download or read book Cytotoxic T Lymphocytes in Human Viral and Malaria Infections written by Michael B.A. Oldstone and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytotoxic T lymphocytes (CTL) control several viral infections in animals based on deletion and reconstitution experiments with CTL clones and use of CD8 genetically deficient (knock-out) mice. In this volume, data for the role that CTL play in human infectious diseases is presented. As such, this represents the first volume in which such information from several different viral and protozoan infections is brought together.
Download or read book Structure of Antigens written by Marc H. V. Van Regenmortel and published by CRC Press. This book was released on 1995-12-20 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 3 of Structure of Antigens presents analytical methods used to elucidate the structure of antigens. As in the first two volumes, this reference focuses on the structure and analysis of antibody binding sites. It brings together the structural basis of major types of antigens, including lysozyme, cytochrome c, muscle proteins, cereal and milk proteins, carbohydrate antigens, and more. Major groups of antigens associated with particular biological systems, such as the cytoskeleton, muscle proteins, and viral antigens, are discussed. This reference analyzes the molecular basis of antibody specificity and the structure of T cell epitopes.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1844 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book MHC Ligands and Peptide Motifs written by Hans-Georg Rammensee and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is centered on a comprehensive list of MHC peptide motifs and ligands as known to date, together with selected T cell epitopes, arranged in an easy-to-read fashion. This information is put into context by chapters on MHC gene organization, MHC structure, T cell epitope prediction, antigen processing and T cell responses. In addition, the book provides a great deal of complementary information: amino acid sequences of MHC class I alpha1 and alpha2 domains and of class II alpha1 and beta1 domains, the established or predicted composition and specificity of MHC pockets, notes on MHC nomenclature including old assignments and reference to useful internet addresses. A handy reference manual that should be helpful for all those dealing with MHC-associated peptides.
Download or read book Vaccines97 written by Cold Spring Harbor Laboratory and published by CSHL Press. This book was released on 1997 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over its lifespan so far, this annual series has traced the state of the art of vaccination from empiricism to molecular design. In this work, the investigation of immunogens at a structural level is especially prominent, as is further exploration of DNA immunization.
Download or read book Persistent Viral Infections written by R. Ahmed and published by Wiley-Blackwell. This book was released on 1999 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal models that provide, or have the potential to provide, major insights This volume will be essential reading for virologists, immunologists, oncologists and neurologists.
Download or read book Rinderpest and Peste des Petits Ruminants written by William P. Taylor and published by Elsevier. This book was released on 2005-11-15 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rinderpest and Peste des Petits Ruminants tells the story of how, by the year 2010, scientists are set to globally eradicate one of the great historic plagues that has ravaged human livestock for centuries. Descriptions of the disease in Europe date back to the 4th century and it was regularly re-introduced following wars and other civil unrest until late in the 19th century. It was introduced with devastating effect into Africa towards the end of the 19th century and is now widespread across sub-Saharan Africa, the Middle East and Southern Asia. Its causative agent, rinderpest virus, a morbillivirus very closely related to human measles virus, decimates the cattle population along with those of other susceptible domestic ruminants and many wildlife species wherever it is present. The history of Rinderpest including the history of vaccines and vaccination Details other Morbillaviruses Epidemiology and transmission of Rinderpest
Download or read book Chemical Abstracts written by and published by . This book was released on 2002 with total page 2540 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetic Immunization written by Adrian Bot and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wolf's discovery demonstrating that a reporter gene is expressed in myocytes subsequent to injection of naked DNA, was exploited by immunologists and vaccinologists to develop a new generation of vaccines. This observation galvanized the research and in a short lapse of time, an oceanic volume of knowledge has been accumulated. The research carried out in a variety of animal models showed the efficacy of genetic immunization against viruses, bacteria, and some parasites by the ability to induce a strong priming effect resulting from long-lasting persistence of plasmid as episomes. Furthermore, it was demonstrated that newborn or infant immune unresponsiveness to classical vaccines can be corrected by genetic immunization. The applications of genetic immunization for prophylaxis of infections was extended to immunotherapy, namely, cancerous, auto immune, and allergic diseases. Immunologists have provided pertinent information on the cellular basis of the immune responses elicited by genetic immunization, and molecular biologists have established the molecular basis of intrinsic adjuvant properties of plasmids.
Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Download or read book The Journal of Immunology written by and published by . This book was released on 2006 with total page 940 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book HLA and MHC written by Michael J. Browning and published by Taylor & Francis. This book was released on 1996 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a review of the major histocompatibility complex (MHC), and the role it plays in the immune response and in disease. The emphasis throughout is on the human MHC, but relevant animal studies are inclded to give a comprehensive review of the subject.
Download or read book Clinical Applications of Immunomics written by Andras Falus and published by Springer Science & Business Media. This book was released on 2008-12-23 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Innate immunity is one the most evolutionally conserved systems, designed to protect the organism from viruses and bacterial infections, stress and many other types of attacks from the outside world. During the past decade, the capacity of molecular biology and information technology to produce and analyse data have grown exponentially, rapidly reforming many aspects of immunology research in the post-genomics era. As a result, scientific understanding of signalling networks governing the innate immunity response in human tissues and other organisms has evolved beyond recognition, compared to even just a decade ago. Many strategies have been designed over the years to identify novel proteins, which have a crucial role in innate immunity responses by regulating particular signalling pathways. These projects had many advantages, including the definition of novel drug targets, as exemplified by the recent success of anti-TNF therapy, as well as leading to a better, system-wide understanding of the molecular control of innate immunity. In the past few years, a new concept, Immunomics, has been adopted to define an emerging, multidisciplinary field of research (Schonbach, 2003). Although rapid progress has been made to identify the proteins playing pivotal roles in the innate immunity–related signalling pathways (for example, TIR signalling pathways), the catalogue of proteins with a key regulatory function identified and studied is far from completed. Novel proteins need to be char- terised to gain a more comprehensive picture of how signalling networks are regulated.
Download or read book Current Opinion in Infectious Diseases written by and published by . This book was released on 1994 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:
