Download or read book Identification of Biomarkers New Treatments and Vaccines for COVID 19 written by Paul C. Guest and published by Springer Nature. This book was released on 2021-07-19 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just one year. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as diabetes and obesity. As the cases and death rate remain high, there are justified fears of this virus remaining for several months or years to come. To address this, a rapid and unprecedented worldwide mobilization effort has begun to identify effective treatments and develop vaccines. As these begin to be deployed and administered across the globe, many now feel the virus will be brought under control and lives will eventually return to normal. This new volume will increase readers’ understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss new treatment approaches, vaccine development, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers.

Download or read book Application of Omic Techniques to Identify New Biomarkers and Drug Targets for COVID 19 written by Paul C. Guest and published by Springer Nature. This book was released on 2023-06-28 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected nearly every country and territory in the world. Although worldwide vaccination efforts have reduced the risk of serious disease outcomes, disparities in distribution have led to multiple waves of SARS-CoV-2 outbreaks and the emergence of variants of concern, some of which have enhanced infectivity and ability to evade existing vaccines. Hence there is an increasing interest in understanding the evolution of viruses like SARS-CoV-2, as well as improving our capacity to effectively current and manage future pandemics. This new volume reviews the most effective omic techniques for increasing our understanding of COVID-19, to improve diagnostics, prognostics, and genomic surveillance, and to facilitate development of effective treatments and vaccines. Chapters are written by an international team of experts and explore methods in the areas of genomics, transcriptomics, proteomics, and metabolomics. Techniques used to assess physiological function at the molecular level and artificial intelligence approaches used for more effective validation and translation of biomarker candidates into clinical use are also discussed. This book is an excellent resource for researchers studying biomarkers, virology, metabolic diseases, and infectious diseases, as well as clinical scientists, physicians, drug company scientists, and healthcare workers.

Download or read book Multiplex Biomarker Techniques written by Paul C. Guest and published by Springer Nature. This book was released on 2022-07-15 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores the application of multiplex biomarker methods in the critical area of COVID-19 research through state-of-the-art technologies in the fields of genomics, proteomics, transcriptomics, metabolomics, and imaging. The book features a series of protocols from labs across the globe employing multiplex molecular approaches, which can be applied to accelerate progress in the research of SARS-CoV-2 and other infectious illnesses. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and essential, Multiplex Biomarker Techniques: Methods and Applications for COVID-19 Disease Diagnosis and Risk Stratification serves as a vital resource for researchers in the areas of virology, metabolic diseases, respiratory disorders, as well as to clinical scientists, physicians, pharmacologists, and the healthcare services.

Download or read book International and Life Course Aspects of COVID 19 written by Rajkumar Rajendram and published by Elsevier. This book was released on 2024-06-28 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: International and Life Course Aspects of COVID-19 describes the nuances and international variations of COVID-19 in different populations and age groups. This volume details those differences in chapters examining the effects of the virus at different life stages, including newborns, children, adolescents, and older populations. Consideration of the age-specific effects of COVID-19 on the brain are a major focus unique to this resource. International observations and global outcomes are also described. This volume is relevant for all clinicians working to ensure the best outcomes for patients with COVID-19 worldwide. Examines COVID-19 symptoms and concerns according to age Discusses outcomes related to global populations and differences observed in symptomatology and care Focuses on the brain, with a look at developmental changes in pregnancy, newborns, childhood, and adolescence Describes mental health impacts in the older populations Features individual chapter introductions and summaries to provide a comprehensive introduction Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures

Download or read book Pandemic Communication written by Stephen M. Croucher and published by Taylor & Francis. This book was released on 2023-02-28 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book details how the processes of communication are affected by the presence of a pandemic and establishes a research agenda for those effects across the broad field of communication studies. Through contributions from experts in communication subdisciplines such as crisis, organizational, interpersonal, health, intergroup, and intercultural, this book provides the reader with a comprehensive view of the emerging field of study "pandemic communication." Each chapter has four primary objectives to: (1) define critical issues for pandemic communication from its subdiscipline’s perspective, (2) examine how communication varies during pandemic(s), (3) provide examples of how pandemic(s) havefor affected communication, and (4) propose a research agenda to build pandemic communication theory. This book is suited to undergraduate or post-graduate courses or modules in communication studies across a variety of subdisciplines as well as a reference for researchers in the subject.

Download or read book Sex Differences in Inflammatory Diseases written by Antonietta Rossi and published by Frontiers Media SA. This book was released on 2022-08-05 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mosaic of Autoimmunity written by Carlo Perricone and published by Academic Press. This book was released on 2019-02-15 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis. Highlights the concept of the mosaic of autoimmune manifestations Includes new visions on unsuspected molecules Provides updated knowledge to physicians helping patients with autoimmune diseases Presents thorough, up-to-date information on specific diseases, along with clinical applications

Download or read book Pandemics Insurance and Social Protection written by María del Carmen Boado-Penas and published by Springer Nature. This book was released on 2022 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book collects expert contributions on actuarial modelling and related topics, from machine learning to legal aspects, and reflects on possible insurance designs during an epidemic/pandemic. Starting by considering the impulse given by COVID-19 to the insurance industry and to actuarial research, the text covers compartment models, mortality changes during a pandemic, risk-sharing in the presence of low probability events, group testing, compositional data analysis for detecting data inconsistencies, behaviouristic aspects in fighting a pandemic, and insurers' legal problems, amongst others. Concluding with an essay by a practicing actuary on the applicability of the methods proposed, this interdisciplinary book is aimed at actuaries as well as readers with a background in mathematics, economics, statistics, finance, epidemiology, or sociology.

Download or read book Detection and Analysis of SARS Coronavirus written by Chaudhery Mustansar Hussain and published by John Wiley & Sons. This book was released on 2021-08-23 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detection and Analysis of SARS Coronavirus Detecting and analyzing the COVID-19 pandemic with biosensor technology The highly contagious SARS CoV-2 pathogen has challenged health systems around the world as they struggle to detect and monitor the spread of the pathogen. In Detection and Analysis of SARS Coronavirus: Advanced Biosensors for Pandemic Viruses and Related Pathogens expert chemists Chaudhery Mustansar Hussain and Sudheesh K. Shukla deliver a practical analysis of how contactless coronavirus detectors may be developed using existing biosensor technology. The editors outline current challenges in the field, the bioanalytical principles for coronavirus detection, and available biosensor technology. They then move on to how available technology might be adapted to detect coronaviruses and how commercialization of the technology might unfold. The lessons learned in this book are readily applicable to the study of other current and emerging pathogens. Readers will also enjoy: A thorough introduction to the current diagnostic approaches for COVID-19, including common challenges, technology adaptation, and future potential An exploration of bio-analytical strategies for SARS CoV-2/COVID-19, including COVID detection via nanotechnology, biosensing approaches, and the role of nanotechnology in coronavirus detection Practical discussions of biosensors for the analysis of SARS CoV-2/COVID-19, including sensor development for coronavirus and chemical sensors for coronavirus diagnosis In-depth treatments of the commercialization and standardization for analytical technologies Perfect for virologists, pharmaceutical industry professionals, and sensor developers, Detection and Analysis of SARS Coronavirus is also an indispensable resource for those working in analytical research institutes, biotechnology industry professionals, and public health agency professionals.

Download or read book Applications of Artificial Intelligence in COVID 19 written by Sachi Nandan Mohanty and published by Springer Nature. This book was released on 2021-09-29 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book examines the role of artificial intelligence during the COVID-19 pandemic, including its application in i) early warnings and alerts, ii) tracking and prediction, iii) data dashboards, iv) diagnosis and prognosis, v) treatments, and cures, and vi) social control. It explores the use of artificial intelligence in the context of population screening and assessing infection risks, and presents mathematical models for epidemic prediction of COVID-19. Furthermore, the book discusses artificial intelligence-mediated diagnosis, and how machine learning can help in the development of drugs to treat the disease. Lastly, it analyzes various artificial intelligence-based models to improve the critical care of COVID-19 patients.

Download or read book MicroRNA Profiling written by Sweta Rani and published by Springer Nature. This book was released on 2022-11-28 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides updated and comprehensive methods on miRNA biogenesis and their role in the development and progression of various human diseases. Chapters detail miRNA biogenesis, isolating RNA, extracellular vesicles (EVs), circulating miRNAs, analyzing miRNA and miRDeep-P2, protocols for total RNA isolation from cells, cell-derived products, isolation and characterization of exosomes, serum, plasma specimens, and software tools. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, MicroRNA Profiling: Methods and Protocols, Second Edition aims to provide comprehensive and accessible methods to undergraduate, graduate, and established scientist.

Download or read book Deep Learning Approaches for Early Diagnosis of Neurodegenerative Diseases written by Rodriguez, Raul Villamarin and published by IGI Global. This book was released on 2024-02-14 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the context of global health challenges posed by intractable neurodegenerative diseases like Alzheimer's and Parkinson's, the significance of early diagnosis is critical for effective intervention, and scientists continue to discover new methods of detection. However, actual diagnosis goes beyond detection to include a significant analysis of combined data for many cases, which presents a challenge of several complicated calculations. Deep Learning Approaches for Early Diagnosis of Neurodegenerative Diseases stands as a groundbreaking work at the intersection of artificial intelligence and neuroscience. The book orchestrates a symphony of cutting-edge techniques and progressions in early detection by assembling eminent experts from the domains of deep learning and neurology. Through a harmonious blend of research areas and pragmatic applications, this monumental work charts the transformative course to revolutionize the landscape of early diagnosis and management of neurodegenerative disorders. Within the pages, readers will embark through the intricate landscape of neurodegenerative diseases, the fundamental underpinnings of deep learning, the nuances of neuroimaging data acquisition and preprocessing, the alchemy of feature extraction and representation learning, and the symphony of deep learning models tailored for neurodegenerative disease diagnosis. The book also delves into integrating multimodal data to augment diagnosis, the imperative of rigorously evaluating and validating deep learning models, and the ethical considerations and challenges entwined with deep learning for neurodegenerative diseases.

Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Download or read book Inflammation in Psychiatry written by Angelos Halaris and published by Karger Medical and Scientific Publishers. This book was released on 2013 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: An innovative and integrative avenue toward understanding and treating mental health disorders Psychoimmunology is a rapidly maturing area of scientific endeavor that provides a compelling integrative link between the immune system and its response to stress and psychiatric illness. Stress initiates pathological changes by activating the immune and endocrine systems. Inflammation is at the core of the complex and interactive systems that both contribute to and result from psychopathology. Consequently, inflammation research advances our knowledge of the pathology of depression, schizophrenia, chronic fatigue syndrome, posttraumatic stress disorder and a host of co- morbid conditions, notably diabetes, cardiovascular disease and cerebrovascular disease. The possible mechanisms underlying the bidirectionality of co-morbid medical and psychiatric disorders can be viewed as a consequence of inflammatory changes. These emerging novel concepts illustrate how the knowledge of inflammation can enable meaningful integration of psychopathology with physical co- morbidity. The innovative articles in this volume highlight the intricate link between psychiatry and psychoimmunology and underscore the central role of inflammation in furthering our understanding of the pathophysiology underlying mental health and illness.

Download or read book Rapid Expert Consultations on the COVID 19 Pandemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-05-30 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to a request from the Office of Science and Technology Policy and the Office of the Assistant Secretary for Preparedness and Response, the National Academies of Sciences, Engineering, and Medicine convened a standing committee of experts to help inform the federal government on critical science and policy issues related to emerging infectious diseases and other 21st century health threats. This set of Rapid Expert Consultations are the first of their kind and represent the best evidence available to the Committee at the time each publication was released. The science on these issues is continually evolving, and the scientific consensus the Committee reaches on these topics will likely evolve with it. The standing committee includes members with expertise in emerging infectious diseases, public health, public health preparedness and response, biological sciences, clinical care and crisis standards of care, risk communication, and regulatory issues.

Download or read book Current Challenges in Complement Diagnostics written by Erik J.M. Toonen and published by Frontiers Media SA. This book was released on 2023-12-14 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complement system is an important innate immune surveillance network that has a key role in protecting our bodies against pathogens and other threats. It is a highly complex system consisting of approximately 50 soluble and cell surface-bound proteins that interact to eliminate danger signals. These signals include factors such as invading microorganisms, necrotic cells, and immune complexes. Furthermore, complement can link innate and adaptive immune responses by regulating T cell and B cell responses. The complement system is tightly regulated to avoid uncontrolled activation. Dysregulation of the complement system has been linked to numerous diseases, both rare and common. Uncontrolled or exaggerated activation can lead to life-threatening conditions such as dysregulation of coagulation, fibrinolysis, systemic inflammation and shock, and possible failure of a variety of organs such as the eyes, kidneys, skin, brain, and vascular system. In recent years, the complement system has gained increased interest, especially as a promising candidate for therapeutic intervention. Eculizumab, the first approved complement inhibitor, is highly effective for treating atypical hemolytic uremic syndrome (aHUS) and paroxysmal nocturnal hemoglobinuria (PNH). Many more drug candidates are currently evaluated in ongoing clinical trials.

Download or read book Emerging Technologies for Combatting Pandemics written by M. Rubaiyat Hossain Mondal and published by CRC Press. This book was released on 2022-11-25 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The COVID-19 pandemic has significantly affected the healthcare sector across the globe. Artificial Intelligence (AI) and the Internet of Medical Things (IoMT) play important roles when dealing with emerging challenges. These technologies are being applied to problems involving the early detection of infections, fast contact tracing, decision-making models, risk profiling of cohorts, and remote treatment. Applying these technologies runs against challenges including interoperability, lack of unified structure for eHealth, and data privacy and security. Emerging Technologies for Combatting Pandemics: AI, IoMT, and Analytics examines multiple models and solutions for various settings including individual, home, work, and society. The world’s healthcare systems are battling the novel coronavirus, and government authorities, scientists, medical practitioners, and medical services are striving hard to surmount these challenges. This book focuses on the design and implementation of AI-based approaches in the proposed COVID-19 solutions that are enabled and supported by IoMT, sensor networks, cloud and edge computing, robotics, and analytics. It covers technologies under the umbrella of AI that include data science, big data, machine learning (ML), semantic technologies, analytics, and cyber security. Highlights of the book include: Epidemic forecasting models Surveillance and tracking systems IoMT and Internet of Healthcare Things-based integrated systems for COVID-19 Social network analysis systems Radiological image- based diagnosis systems Computational intelligence methods This reference work is beneficial for interdisciplinary students, researchers, and healthcare and technology professionals who need to know how computational intelligence could be used for surveillance, control, prevention, prediction, diagnosis, and potential treatment of the disease.