Download or read book ICRF Handbook of Genome Analysis written by N. S. Spurr and published by John Wiley & Sons. This book was released on 2009-06-03 with total page 1038 pages. Available in PDF, EPUB and Kindle. Book excerpt: The combined power of genetic analysis and recombinant DNA technology to analyse entire genomes has moved biomedical research into a new and revolutionary phase. The complete sequencing and mapping of the human genome, as well as the genomes of other model organisms, will be the basis for our future understanding of human disease, and will allow us to answer fundamental questions about development and evolution. T The new ICRF Handbook of Genome Analysis is the essential guide to the enormous range of techniques available to the researcher for both the genetic and physical mapping of the genome, as well as the sequencing and analysis of DNA. It is both a protocol manual and a comprehensive information resource. Written by international experts, each chapter presents a state-of-the-art review of a methodology. Methods are fully described and evaluated; their advantages and disadvantages discussed; and their suitability for different investigations considered. Step-by-step protocols, including computer analyses, are given for 123 essential experimental procedures. 'Troubleshooting' sections discuss possible reasons for failure and offer remedies. The primary focus is on human genetics and the benefits of an understanding of the genome for the diagnosis and treatment of human disease. The book also considers the current state of progress in the analysis of genomes of many model organisms, including plants. A major part of the work provides detail on Internet resources as well as basic data on human and other genomes, including mapped disease genes and mouse knockouts. Covers not only the human genome in relation to cancers and other human diseases, but also the genomes of all important model organisms Contains 123 easy-to-follow protocols for essential experimental procedures Reviews a vast range of other information resources, including journals and the Internet * provides an invaluable listing of suppliers of laboratory materials Has been written by international experts from their own practical experience Is mandated by the Imperial Cancer Research Fund - a leader in research in this field Has a sturdy spiral binding within a hardback case for ease of use in the lab
Download or read book ICRF handbook of genome analysis 2 written by Nigel K. Spurr and published by . This book was released on 1998 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book ICRF Handbook of Genome Analysis written by Spurr, Nigel K., ed and published by . This book was released on 1998 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book ICRF Handbook of Genome Analysis written by and published by . This book was released on 1998 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genome Analysis written by Eric D. Green and published by CSHL Press. This book was released on 1997 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complement to the bible of recombinant DNA, Molecular Cloning, these manuals are essential for every laboratory in which genes are being studied.
Download or read book Handbook of Comparative Genomics written by Cecilia Saccone and published by John Wiley & Sons. This book was released on 2005-03-11 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference covers the comparative methodologyinvolved in studying molecular evolution. Providing a practicalintroduction to the role of bioinformatics in comparative genomics,this publication further discusses the basic technology used ingenome sequencing projects and provides an overview of genomestorage databases currently in use. This timely and cutting-edge text also: Reviews the basic principles of genomics and gene expressionanalysis Discusses analytic methods in proteomics andtranscriptomics Includes a comprehensive list of Web resource
Download or read book Genome Analysis written by and published by . This book was released on 1997 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complement to the bible of recombinant DNA, Molecular Cloning, these manuals are essential for every laboratory in which genes are being studied.
Download or read book Genome Analysis written by Bruce Birren and published by . This book was released on 2006 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles of Genome Analysis and Genomics written by Sandy B. Primrose and published by John Wiley & Sons. This book was released on 2009-04-01 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the first draft of the human genome project in the publicdomain and full analyses of model genomes now available, thesubject matter of 'Principles of Genome Analysis and Genomics' iseven 'hotter' now than when the first two editions were publishedin 1995 and 1998. In the new edition of this very practical guideto the different techniques and theory behind genomes and genomeanalysis, Sandy Primrose and new author Richard Twyman provide afresh look at this topic. In the light of recent excitingadvancements in the field, the authors have completely revised andrewritten many parts of the new edition with the addition of fivenew chapters. Aimed at upper level students, it is essential thatin this extremely fast moving topic area the text is up to date andrelevant. Completely revised new edition of an establishedtextbook. Features new chapters and examples from exciting new researchin genomics, including the human genome project. Excellent new co-author in Richard Twyman, also co-author ofthe new edition of hugely popular Principles of GeneManipulation. Accompanying web-page to help students deal with this difficulttopic at www.blackwellpublishing.com/primrose
Download or read book Principles of Genome Analysis written by Sandy B. Primrose and published by Wiley-Blackwell. This book was released on 1998-03-30 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome analysis and genomics are at the forefront of current research in the life sciences. Since the first edition of Principles of Genome Analysis was published, the sequencing of genomes has continued apace, with the major landmark of the human genome sequence being achieved in 2001. Now the emphasis of biological research is on genomics: the understanding of gene function and the interaction of gene products at the whole genome level. As before, this book provides a step-by-step outline of the techniques involved in genome mapping and sequencing. Additionally, the text has been greatly expanded to cover sub-disciplines of genomics, revisions of sections on genome sequencing and bioinformatics, and new chapters on comparative genomics, functional genomics and proteomics. The book concludes with an exciting new chapter describing a variety of ways to utilize genome analysis and sequencing in biology, medicine and agriculture. Aimed at advanced undergraduates, this text will follow the same format as the highly successful Principles of Gene Manipulation by Primrose, Twyman and Old, now in its sixth edition.
Download or read book Genome Analysis written by Bruce Birren and published by . This book was released on 2006 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nonmammalian Genomic Analysis written by Bruce Birren and published by Academic Press. This book was released on 1996-09-25 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering detailed protocols for those needing to construct a variety of maps and isolate genes, this unique book is intended to popularize the new techniques of genome analysis derived from the Human Genome Project. The power of these new methods is often most striking when applied to problems outside of human genetics, particularly the nonmammalian systems on which many researchers focus. Many of these organisms are economically important and biologically rich. Nonmammalian Genomic Analysis: A Practical Guide covers the "how to" aspects of preparation, handling, cloning, and analysis of large DNA and the creation of chromosome and genome maps. This lab manual facilitates the transfer of these technologies to small "low tech" environments and allows them to be used by those with no background in genome mapping or large-fragment cloning. Like having a local expert, this collection provides procedures for anyone, anywhere, and allows the replication of others' success. Includes detailed and clearly-written step-by-step protocols Evinces expected results and offers trouble shooting advice Provides techniques appropriate for small laboratories as well as those with limited resources Covers a broad variety of cloning systems, including single copy vectors Discusses a diverse range of organisms, from prokaryotes to eukaryotes, from single-celled organisms to highly complex organisms
Download or read book Collaborative Genomics Projects A Comprehensive Guide written by Margi Sheth and published by Academic Press. This book was released on 2016-02-24 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collaborative Genomics Projects: A Comprehensive Guide contains operational procedures, policy considerations, and the many lessons learned by The Cancer Genome Atlas Project. This book guides the reader through methods in patient sample acquisition, the establishment of data generation and analysis pipelines, data storage and dissemination, quality control, auditing, and reporting. This book is essential for those looking to set up or collaborate within a large-scale genomics research project. All authors are contributors to The Cancer Genome Atlas (TCGA) Program, a NIH- funded effort to generate a comprehensive catalog of genomic alterations in more than 35 cancer types. As the cost of genomic sequencing is decreasing, more and more researchers are leveraging genomic data to inform the biology of disease. The amount of genomic data generated is growing exponentially, and protocols need to be established for the long-term storage, dissemination, and regulation of this data for research. The book's authors create a complete handbook on the management of research projects involving genomic data as learned through the evolution of the TCGA program, a project that was primarily carried out in the US, but whose impact and lessons learned can be applied to international audiences. Establishes a framework for managing large-scale genomic research projects involving multiple collaborators Describes lessons learned through TCGA to prepare for potential roadblocks Evaluates policy considerations that are needed to avoid pitfalls Recommends strategies to make project management more efficient
Download or read book Automation Genomic and Functional Analyses written by Alister G. Craig and published by Elsevier. This book was released on 1999-02 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evaluation and functional analysis, to provide insight into this "new age" of research based on genomic and chemical screening. Key Features * Describes automated procedures used in microbiology and molecular biology * Includes developments in robotics and vision systems * Features automation in library picking, presentation and analysis * Discusses paralogous duplications in microbial genomes * Covers deciphering genomes through automated large-scale sequencing * Describes and stresses the need for functional analyses * Internationally acclaimed contributors, including Professor Leroy Hood.
Download or read book Analyzing DNA written by Bruce Birren and published by . This book was released on 1997 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: MIT Center for Genome Research, Cambridge, MA. First in a four-volume set. Lab manual describing the theoretical background, lab protocols, and resource materials for applying genome analysis techniques to the study of genes and genomes. Plastic-comb spiral binding.
Download or read book Principles of Genome Analysis and Genomics written by Sandy B. Primrose and published by Wiley-Blackwell. This book was released on 2002-12-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the first draft of the human genome project in the public domain and full analyses of model genomes now available, the subject matter of 'Principles of Genome Analysis and Genomics' is even 'hotter' now than when the first two editions were published in 1995 and 1998. In the new edition of this very practical guide to the different techniques and theory behind genomes and genome analysis, Sandy Primrose and new author Richard Twyman provide a fresh look at this topic. In the light of recent exciting advancements in the field, the authors have completely revised and rewritten many parts of the new edition with the addition of five new chapters. Aimed at upper level students, it is essential that in this extremely fast moving topic area the text is up to date and relevant. Completely revised new edition of an established textbook. Features new chapters and examples from exciting new research in genomics, including the human genome project. Excellent new co-author in Richard Twyman, also co-author of the new edition of hugely popular Principles of Gene Manipulation. Accompanying web-page to help students deal with this difficult topic at www.blackwellpublishing.com/primrose
Download or read book E coli written by Michael Donnenberg and published by Elsevier. This book was released on 2002-10-09 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although most strains of E. coli bacteria are harmless and live in the intestines of healthy humans and animals, several strains can produce powerful toxins and cause severe illness in humans. This versatile pathogen is best known for being transmitted to humans through contaminated foods — such as undercooked meat and unpasteurized fruit juice — and has attracts much attention when serious outbreaks occur. E. coli is capable of causing a wide variety of diseases — from urinary tract infections to meningitis. A considerable amount of media coverage has recently been devoted to one particular strain of E. coli, responsible for an estimated 73,000 cases of infection and 61 deaths in the United States each year. Knowing more about the biology, the evolution, and the genetic basis of this pathogen is crucial to future prevention of infection and illness. Pathogenic E. coli is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Pathogenic E. coli concludes with a presentation of virulance factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research. Single source of information of E. coli pathogenesis Expert authors Comprehensive coverage Molecular mechanisms Biology, evolution and genomics Recent advances
