Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Download or read book Something Real written by Heather Demetrios and published by Macmillan. This book was released on 2014-02-04 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the cancellation of her family's reality television show, seventeen-year-old Bonnie Baker, one of twelve siblings, has tried to live a normal life with real friends and a possible boyfriend, until her mother and the show's producers decide to bring "Baker's Dozen" back on the air.

Download or read book Finding Grace written by Janis Thomas and published by Blackstone Publishing. This book was released on 2022-04-12 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A young girl is in terrible danger ... but can they reach her in time? Somebody’s coming for you California: Twelve-year-old Melanie has been in foster care her whole life, moving from home to home—unloved and unwanted. And although she has found relative contentment with her current foster parents, Melanie harbors a secret that, if discovered, would blow her world apart. Someone talks to Melanie, a presence no one else can see or hear, and this presence has a message for her: something bad is about to happen. New York: After years of battling with her troubled, unpredictable mother, Louise has managed to find peace in her solitary existence. Until the day Grace crashes back into her life and entreats Louise to help her save a child from imminent danger. Unwilling to get caught up in her mother’s madness, Louise resists. But she realizes the only way to be rid of Grace once and for all is to play along. Louise and Grace set off across America in search of Melanie, driven by Grace’s firm belief that they have to get there before the bad thing happens. To do that, Louise must first come to understand and trust her mother. But after a lifetime of pain and dysfunction, can the two finally heal old wounds in order to save one young girl?

Download or read book Fahrenheit 451 written by Ray Bradbury and published by Simon and Schuster. This book was released on 2003-09-23 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Set in the future when "firemen" burn books forbidden by the totalitarian "brave new world" regime.

Download or read book Empire of Pain written by Patrick Radden Keefe and published by Anchor. This book was released on 2021-04-13 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • A NEW YORK TIMES NOTABLE BOOK OF THE YEAR • A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and bestselling author of Say Nothing. "A real-life version of the HBO series Succession with a lethal sting in its tail…a masterful work of narrative reportage.” – Laura Miller, Slate The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful. The Sackler name has adorned the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, but the source of the family fortune was vague—until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. Empire of Pain is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early twentieth-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, D.C. It follows the family’s early success with Valium to the much more potent OxyContin, marketed with a ruthless technique of co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability. A masterpiece of narrative reporting, Empire of Pain is a ferociously compelling portrait of America’s second Gilded Age, a study of impunity among the super-elite and a relentless investigation of the naked greed that built one of the world’s great fortunes.

Download or read book Community Management of Opioid Overdose written by World Health Organization and published by . This book was released on 2015-09-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An estimated 69000 people die each year from opioid overdose. Opioid overdose is easily reversed with the opioid antidote naloxone and with basic life support. Such care is generally only available in medical settings, however. These guidelines recommend that people who are likely to witness an opioid overdose, including people who use opioids, and their family and friends should be given access to naloxone and training in its use so that they can respond to opioid overdose in an emergency if a medical response is not available. Naloxone can be injected or administered intra-nasally and has minimal effects in people who have not used opioids. While naloxone administered by bystanders is a potentially life-saving emergency interim response to opioid overdose, it should not be seen as a replacement for comprehensive medical care.

Download or read book On Earth We re Briefly Gorgeous written by Ocean Vuong and published by Penguin. This book was released on 2021-06-01 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: The instant New York Times Bestseller • Nominated for the 2019 National Book Award for Fiction “A lyrical work of self-discovery that’s shockingly intimate and insistently universal…Not so much briefly gorgeous as permanently stunning.” —Ron Charles, The Washington Post Ocean Vuong’s debut novel is a shattering portrait of a family, a first love, and the redemptive power of storytelling On Earth We’re Briefly Gorgeous is a letter from a son to a mother who cannot read. Written when the speaker, Little Dog, is in his late twenties, the letter unearths a family’s history that began before he was born — a history whose epicenter is rooted in Vietnam — and serves as a doorway into parts of his life his mother has never known, all of it leading to an unforgettable revelation. At once a witness to the fraught yet undeniable love between a single mother and her son, it is also a brutally honest exploration of race, class, and masculinity. Asking questions central to our American moment, immersed as we are in addiction, violence, and trauma, but undergirded by compassion and tenderness, On Earth We’re Briefly Gorgeous is as much about the power of telling one’s own story as it is about the obliterating silence of not being heard. With stunning urgency and grace, Ocean Vuong writes of people caught between disparate worlds, and asks how we heal and rescue one another without forsaking who we are. The question of how to survive, and how to make of it a kind of joy, powers the most important debut novel of many years. Named a Best Book of the Year by: GQ, Kirkus Reviews, Booklist, Library Journal, TIME, Esquire, The Washington Post, Apple, Good Housekeeping, The New Yorker, The New York Public Library, Elle.com, The Guardian, The A.V. Club, NPR, Lithub, Entertainment Weekly, Vogue.com, The San Francisco Chronicle, Mother Jones, Vanity Fair, The Wall Street Journal Magazine and more!

Download or read book Hooked written by Howard Brody and published by Rowman & Littlefield. This book was released on 2007 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades, medical professionals have betrayed the public's trust by accepting various benefits from the pharmaceutical industry. Both drug company representatives and doctors employ artful spin to portray this behavior positively to the public, and to themselves. In Hooked, Howard Brody argues that we can neither understand the problem, nor propose helpful solutions until we identify the many levels of activity connecting these purportedly noble industries. We can pass laws and enact regulations, but ultimately the medical profession must take responsibility for its own integrity. Hooked is a wake-up call for anyone expecting high quality, ethical medical care.

Download or read book Children and Drug Safety written by Cynthia A Connolly and published by Rutgers University Press. This book was released on 2018-05-11 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the 2018 Arthur J. Viseltear Award from the Medical Care Section of the American Public Health Association​ Children and Drug Safety traces the development, use, and marketing of drugs for children in the twentieth century, a history that sits at the interface of the state, business, health care providers, parents, and children. This book illuminates the historical dimension of a clinical and policy issue with great contemporary significance—many of the drugs administered to children today have never been tested for safety and efficacy in the pediatric population. Each chapter of Children and Drug Safety engages with major turning points in pediatric drug development; themes of children’s risk, rights, protection and the evolving context of childhood; child-rearing; and family life in ways freighted with nuances of race, class, and gender. Cynthia A. Connolly charts the numerous attempts by Congress, the Food and Drug Administration, the American Academy of Pediatrics, and leading pediatric pharmacologists, scientists, clinicians, and parents to address a situation that all found untenable. Open access edition funded by the National Endowment for the Humanities. The text of this book is licensed under a Creative Commons Attribution NonCommercial-NoDerivatives 4.0 International License: https://creativecommons.org/licenses/by-nc-nd/4.0/

Download or read book Falling Into the Fire written by Christine Montross and published by Penguin. This book was released on 2014-07-29 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Falling Into the Fire is psychiatrist Christine Montross’s thoughtful investigation of the gripping patient encounters that have challenged and deepened her practice. The majority of the patients Montross treats in Falling Into the Fire are seen in the locked inpatient wards of a psychiatric hospital; all are in moments of profound crisis. We meet a young woman who habitually commits self-injury, having ingested light bulbs, a box of nails, and a steak knife, among other objects. Her repeated visits to the hospital incite the frustration of the staff, leading Montross to examine how emotion can interfere with proper care. A recent college graduate, dressed in a tunic and declaring that love emanates from everything around him, is brought to the ER by his concerned girlfriend. Is it ecstasy or psychosis? What legal ability do doctors have to hospitalize—and sometimes medicate—a patient against his will? A new mother is admitted with incessant visions of harming her child. Is she psychotic and a danger or does she suffer from obsessive thoughts? Her course of treatment—and her child’s future—depends upon whether she receives the correct diagnosis. Each case study presents its own line of inquiry, leading Montross to seek relevant psychiatric knowledge from diverse sources. A doctor of uncommon curiosity and compassion, Montross discovers lessons in medieval dancing plagues, in leading forensic and neurological research, and in moments from her own life. Beautifully written, deeply felt, Falling Into the Fire brings us inside the doctor’s mind, illuminating the grave human costs of mental illness as well as the challenges of diagnosis and treatment. Throughout, Montross confronts the larger question of psychiatry: What is to be done when a patient’s experiences cannot be accounted for, or helped, by what contemporary medicine knows about the brain? When all else fails, Montross finds, what remains is the capacity to abide, to sit with the desperate in their darkest moments. At once rigorous and meditative, Falling Into the Fire is an intimate portrait of psychiatry, allowing the reader to witness the humanity of the practice and the enduring mysteries of the mind

Download or read book The Wolf Wants In written by Laura McHugh and published by Random House Trade Paperbacks. This book was released on 2020-05-26 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Calling all fans of Sharp Objects and the third season of True Detective: You need to read Laura McHugh.”—Refinery29 “A perfect thriller . . . a thoughtful commentary on America’s opioid crisis and an utterly satisfying mystery.”—Janelle Brown, New York Times bestselling author of Watch Me Disappear NAMED ONE OF THE BEST BOOKS OF THE YEAR BY LIBRARY JOURNAL Sadie Keller is determined to find out how her brother died, even if no one else thinks it’s worth investigating. Untimely deaths are all too common in rural Blackwater, Kansas, where crime and overdoses are on the rise, and the small-town police force is consumed with the recent discovery of a child’s skull in the woods. Sadie is on her own, delving into the dark corners of a life her brother kept hidden and unearthing more questions than answers. Eighteen-year-old Henley Pettit knows more than she’d like to about the seedy side of Blackwater, and she’s desperate to escape before she’s irreparably entangled in her family’s crimes. She dreams of disappearing and leaving her old life behind, but shedding the past is never easy, and getting out of town will be far more dangerous than she ever imagined. As more bones are found in the woods, time is running out for Sadie to uncover the truth and for Henley to make her escape. Both women are torn between family loyalties and the weight of the secrets they carry, knowing full well that while some secrets are hard to live with, others will get you killed. Like Laura McHugh’s previous award-winning thrillers, The Weight of Blood and Arrowood, The Wolf Wants In is an atmospheric, beautifully told novel that barrels toward a twisting, chilling end and keeps us turning the page to find out how these small-town secrets will unravel—and who will survive. Praise for The Wolf Wants In “The Wolf Wants In perfectly balances gripping suspense with stunning, lyrical prose—a rare combination, but one that seems to be McHugh’s signature gift. Atmospheric and chilling, this novel takes place in the twisted, destructive wake of the opioid crisis as one woman struggles for justice and another for redemption. A truly thrilling read.”—Jill Orr, author of the Riley Ellison mysteries

Download or read book This is How I Find Her written by Sara Polsky and published by Albert Whitman & Company. This book was released on 2013-09-01 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Best Children's Books of the Year 2014, Bank Street College Sophie has always lived her life in the shadow of her mother's bipolar disorder: monitoring medication, making sure the rent is paid, rushing home after school instead of spending time with friends, and keeping secrets from everyone. But when a suicide attempt lands Sophie's mother in the hospital, Sophie no longer has to watch over her. She moves in with her aunt, uncle, and cousin—a family she's been estranged from for the past five years. Rolling her suitcase across town to her family's house is easy. What's harder is figuring out how to rebuild her life. And as her mother's release approaches and the old obligations loom, Sophie finds herself torn between her responsibilities toward her mother and her desire to live her own life, Sophie must decide what to do next.

Download or read book American Overdose written by Chris McGreal and published by PublicAffairs. This book was released on 2018-11-13 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive portrait of a uniquely American epidemic -- devastating in its findings and damning in its conclusions The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs, but the corrupting of medicine and public institutions that let the opioid makers get away with it. The starting point for McGreal's deeply reported investigation is the miners promised that opioid painkillers would restore their wrecked bodies, but who became targets of "drug dealers in white coats." A few heroic physicians warned of impending disaster. But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers -- resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

Download or read book Bad Pharma written by Ben Goldacre and published by Macmillan. This book was released on 2014-04 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 2012, revised edition published in 2013, by Fourth Estate, Great Britain; Published in the United States in 2012, revised edition also, by Faber and Faber, Inc.

Download or read book Fentanyl Inc written by Ben Westhoff and published by Atlantic Monthly Press. This book was released on 2019-09-03 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: A four-year investigation into the world of synthetic drugs—from black market factories to users & dealers to harm reduction activists—and what it revealed. A deeply human story, Fentanyl, Inc. is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. “A whole new crop of chemicals is radically changing the recreational drug landscape,” writes Ben Westhoff. “These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs” —and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice—and those with arcane acronyms like 25i-NBOMe—were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs’ effects impossible to predict. Westhoff has infiltrated this shadowy world. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Westhoff visits the shady factories in China from which these drugs emanate, providing startling and original reporting on how China’s vast chemical industry operates, and how the Chinese government subsidizes it. Poignantly, he chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the United States and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many. “Timely and agonizing. . . . An impressive work of investigative journalism.” —USA Today “Westhoff explores the many-tentacled world of illicit opioids, from the streets of East St. Louis to Chinese pharmaceutical companies, from music festivals deep in the Michigan woods to sanctioned ‘shooting up rooms’ in Barcelona, in this frank, insightful, and occasionally searing exposé. . . . Westhoff’s well-reported and researched work will likely open eyes, slow knee-jerk responses, and start much needed conversations.” —Publishers Weekly “Our 25 Favorite Books of 2019” —St. Louis Post-Dispatch “Best Books of 2019” —Buzzfeed “Best Nonfiction of 2019” —Kirkus Reviews “50 Best Books of 2019” —Daily Telegraph “Best Nonfiction Books of 2019” —Tyler Cowen “Best Books of 2019” —Yahoo Finance

Download or read book Currents Concerns and Composition written by Thomas Edward Sanders and published by . This book was released on 1971 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book But Knot for Me written by Betty Hechtman and published by Beyond The Page. This book was released on 2021-11-16 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: “The California seaside is the backdrop to this captivating cozy that will have readers heading for the yarn store in droves.” —Debbie’s Book Bag on Yarn to Go In a new Yarn Retreat Mystery from national bestselling author Betty Hechtman, Casey Feldstein has to face down a self-help guru who may have helped himself to murder . . . When a charismatic life coach and his devoted followers descend on Vista Del Mar, Casey Feldstein and the yarn retreat group she’s hosting literally get pushed aside, out of sight and out of mind of the struggling participants seeking enlightenment. But Casey can’t help overhearing the rancorous argument between two members of the guru’s staff, and when one of them turns up dead after ingesting poisonous mushrooms, Casey finds herself tangled up in a murder investigation while the self-help group looks on helplessly. With rumors swirling that the victim was having an affair with the group’s leader and a host of potential suspects among her own eccentric yarn retreat group, Casey can only knit her brow at the complexity of the case. And when another staff member turns up dead and Casey narrowly escapes an early demise of her own, she knows she’ll have to unravel the clues quickly to catch a killer who may be feeling more empowered than even the guru intended . . . Includes a fun and easy crochet project and a mouthwatering muffin recipe! Praise for the Yarn Retreat Mysteries: “If you haven’t read this series yet, I highly recommend giving it a go. The mystery will delight you, and afterward you’ll be itching to start a knitting or crochet project of your own.” —Cozy Mystery Book Reviews “A cozy mystery that you won’t want to put down. It combines cooking, knitting and murder in one great book!” —Fresh Fiction on Yarn to Go