Download or read book Human Retrovirology written by Jörg Schüpbach and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a concise review of the known human retroviruses; the onco-retroviruses HTLV-1 and -2 and the AIDS-associated lentiviruses HIV-1 and -2. History, classification, general and genomic structure, and basic biologic facts of retroviruses are described in introductory chapters. Subsequent chapters deal with the epidemiology, disease spectrum, structure and functions of the viral genes and proteins of the individual viruses. A separate chapter describes the various humoral and cellular immune mechanisms in response to HIV and their use with respect to diagnosis and treatment. Special attention is given to the complicated pathogenesis of AIDS and the consequences with regard to therapy and vaccination. The book ends with a critical review of recent work suggesting a possible role of still other retroviruses in human disorders including malignancies, autoimmune, or neurologic diseases. The book is designed to give the reader a broad, but detailed view of human retroviruses and the diseases associated with them. It tries to connect the viral, immunologic, and pathologic aspects of these infections to unifying concepts - no quick answers though, but profound critical information on a complicated topic.
Download or read book Retroviruses written by John M. Coffin and published by CSHL Press. This book was released on 1997 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over 25 years the study of retroviruses has underpinned much of what is known about information transfer in cells and the genetic and biochemical mechanisms that underlie cell growth and cancer induction. Emergent diseases such as AIDS and adult T-cell lymphoma have widened even further the community of investigators directly concerned with retroviruses, a development that has highlighted the need for an integrated understanding of their biology and their unique association with host genomes. This remarkable volume satisfies that need. Written by a group of the field's most distinguished investigators, rigorously edited to provide a seamless narrative, and elegantly designed for clarity and readability, this book is an instant classic that demands attention from scientists and physicians studying retroviruses and the disorders in which they play a role.
Download or read book Human Retrovirology written by Jorg Schupbach and published by . This book was released on 2014-01-15 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human Retrovirology written by Mariana Warne and published by . This book was released on 2019-06-25 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The type of RNA viruses which insert a copy of their genome into the DNA of the host cells that they invade, and consequently change the genome of, are called retroviruses. After entering the host cell's cytoplasm, the retroviruses use their own reverse transcriptase enzyme to produce DNA from their RNA genome. The study of retroviruses and the diseases caused by them, is called retrovirology. Retroviruses, including Mouse mammary and Rous sarcoma virus can cause diseases, like tumor and cancer. The transmission of retroviruses can be airborne, from cell-to-cell, or through fluids. Antiretroviral drugs are the common medications used for treating the infection caused by retroviruses. This book elucidates the concepts and innovative models around prospective developments with respect to human retrovirology. It includes some of the vital pieces of work being conducted across the world, on various topics related to human retrovirology. This book will help new researchers by foregrounding their knowledge in this branch.
Download or read book Human Retrovirology written by William A. Blattner and published by Raven Press (ID). This book was released on 1990 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book International Symposium Retroviruses and Human Pathology written by Robert C. Gallo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective in mind, we present here a survey that includes general overviews, minireviews on each animal system studied with selected experimental reports and, finally, a stimulating review of the field of human retrovirology by many of the pioneer scientists who created it. We are especially grateful to Profs. C. A. Romanzi and G. C. Schito for promoting the organization of the Symposium. On behalf of the Sym posium Committee, we thank E. Soeri, L. Casarino, G. P. Gesu, M.
Download or read book The Human Retroviruses written by Robert C. Gallo and published by Elsevier. This book was released on 2012-12-02 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents twenty-four tightly focused reviews on the biology, molecular biology, pathology, and epidemiology of the human retroviruses, particularly HIV and HTLV (Types I and II), as well as animal model systems (simian retroviruses, STLV and SIV, and mouse models).Editor Robert C. Gallo is recognized as a co-discoverer of the AIDS virus.
Download or read book Human Retrovirus Protocols written by Tuofu Zhu and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cutting-edge collection of basic and state-of-the-art methods optimized for investigating the molecular biology of this class of retrovirus. These readily reproducible techniques range from methods for the isolation and detection of human retroviruses to cutting-edge methods for exploring the interplay between the viruses and the host. Here, the researcher will find up-to-date techniques for the isolation and propagation of HIV, HTLV, and foamy virus from a variety of sources. There are also assays for determining the cell tropism of HIV-1, the coreceptor usage of HIV-1, and human gene expression with HIV-1 infection by microarrays, as well as for phenotyping HIV-1 infected monocytes and examining their fitness. Highlights include the detection and quantification of HIV-1 in resting CD4+, a new cloning system for making recombinent virus, cDNA microarrays, and the determination of genetic polymorphisms in two recently identified HIV-1 co-factors that are critical for HIV-1 infection.
Download or read book Transacting Functions of Human Retroviruses written by Irvin S.Y. Chen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The coding domains of simple retrovirus genomes direct the synthesis of virion proteins. Complex retroviral genomes generate in addition to virion proteins regulatory transacting proteins that are translated from multiple spliced messenger RNAs and fulfill important functions in the virus life cycle. All human retroviruses have such complex genomes. The transacting proteins of these pathogens are attractive targets for therapeutic intervention because they are viral specific, are essential for efficient virus replication and may be mediators of viral pathogenicity. In summarizing the current knowledge on the regulatory transacting proteins of human retroviruses this volume makes an important contribution toward the control of virus disease.
Download or read book Recent Advances in Human Retroviruses written by A. M. L. Lever and published by World Scientific. This book was released on 2010 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are three major types of human retroviruses, namely HIV, HTLV, and endogenous human retroviruses. This book presents the latest findings on the replication of these human retroviruses. This book is unique in that there has been no comparable book that integrates the findings from the three known classes of human retroviruses. Other books have focused on one of the three classes of human retroviruses individually. An accomplished international team of contributing authors have combined their expertise to provide cutting-edge findings in this important field. The book will be a valuable reference for students, researchers and medical professionals.
Download or read book Human Retroviruses written by Elisa Vicenzi and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Retroviruses: Methods and Protocols collects key experimental protocols that have provided the basis of the major discoveries of the field. Split into five sections, this detailed volume covers mapping of the HIV life cycle, isolation, co-receptor use, and cell tropism of HIV-1, in vivo quantification of HIV-1, biological aspects of HIV-1, as well as HTLVs. Some articles explore “assay and function of accessory genes”, largely involving the interface between retroviral and host factors, the extracellular role of Tat and Tax, resembling the function of cytokines, and the biotechnological exploitation of HIV as lentiviral vector to carry foreign genes with therapeutic value. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Human Retroviruses: Methods and Protocols provides state-of-art methodological protocols from world leaders in human retrovirology, essential for any lab working this vital field.
Download or read book Retroviruses written by Reinhard Kurth and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Retroviruses and Disease written by Hidesaburo Hanafusa and published by Elsevier. This book was released on 2012-12-02 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Retroviruses and Disease presents a relevant summary of the state of knowledge in both human nonhuman retroviruses. It highlights significant concepts regarding their commonalities and differences in terms of retroviral systems. A section of this book covers the pathogenic human retroviruses and focuses on two. These are HLTV-1 (the first human retrovirus that was isolated) and HIV (the cause of a potent immunological disorder). The life cycle of replication-competent retroviruses, including the murine leukemia viruses and its functions, is discussed in Chapters 1 and 2. The focus of the third chapter is the transformation of Rous sarcoma virus. Meanwhile, Chapter 4 discusses the multiple stages in avian leukosis virus-induced B cell lymphoma. Oncogenes, the molecular basis of human cancer, are also covered in this book. Another virus also discussed in this book is the human T cell leukemia virus. The book is a good reference for students, teachers, specialists, scientists, and researchers in microbiology.
Download or read book Plague written by Kent Heckenlively and published by Simon and Schuster. This book was released on 2014-11-18 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: #10 on Amazon Charts, USA Today Bestseller “This book is my best attempt to tell the truth about my research, the culture in science today which is hostile to new ideas, and what science can really do if allowed to pursue promising areas of inquiries.”—Dr. Judy Mikovits, PhD This is a story for anybody interested in the peril and promise of science at the very highest levels in our country. On July 22, 2009, a special meeting was held with twenty-four leading scientists at the National Institutes of Health to discuss early findings that a newly discovered retrovirus was linked to chronic fatigue syndrome (CFS), prostate cancer, lymphoma, and eventually neurodevelopmental disorders in children. When Dr. Judy Mikovits finished her presentation, the room was silent for a moment, then one of the scientists said, “Oh my God!” The resulting investigation would be like no other in science. For Dr. Mikovits, a twenty-year veteran of the National Cancer Institute, this was the midpoint of a five-year journey that would start with the founding of the Whittemore-Peterson Institute for Neuro-Immune Disease at the University of Nevada, Reno, and end with her as a witness for the federal government against her former employer, Harvey Whittemore, for illegal campaign contributions to Senate Majority Leader Harry Reid. On this journey Dr. Mikovits would face the scientific prejudices against CFS, wander into the minefield that is autism, and through it all struggle to maintain her faith in God and the profession to which she had dedicated her life.
Download or read book International Symposium Retroviruses and Human Pathology written by Robert C. Gallo and published by Humana Press. This book was released on 2011-10-14 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective in mind, we present here a survey that includes general overviews, minireviews on each animal system studied with selected experimental reports and, finally, a stimulating review of the field of human retrovirology by many of the pioneer scientists who created it. We are especially grateful to Profs. C. A. Romanzi and G. C. Schito for promoting the organization of the Symposium. On behalf of the Sym posium Committee, we thank E. Soeri, L. Casarino, G. P. Gesu, M.
Download or read book Current Progress in Retrovirology written by Adeline Foley and published by American Medical Publishers. This book was released on 2021-11-16 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Retrovirology is the study of retroviruses. A retrovirus is a kind of RNA virus that inserts a copy of its genome into the DNA of a host cell, thus changing the genome of that cell. These viruses are either single-stranded RNA or double-stranded DNA viruses. The main viron components found in retroviruses are envelope, RNA and protein. Both animals and humans are affected by retroviruses. It causes tumor growth and certain cancers that are linked with slow infections of animals such as equine infectious anemia. Retroviruses such as HTLV-1 cause cancer called adult T-cell leukemia in human beings. Other retroviruses such as HIV cause AIDS in human beings. The treatment of diseases by retrovirus can be done with the help of antiretroviral drugs and medications. This book unravels the recent studies in the field of retrovirology. It traces the progress of this field and highlights some of its key concepts and applications. It is a vital tool for all researching or studying retrovirology, as it gives incredible insights into emerging trends and concepts.
Download or read book Human Retroviruses and Diseases They Cause written by Jean-Pierre Allain and published by . This book was released on 1988 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
