Download or read book For the Good of Mankind written by Vicki Oransky Wittenstein and published by Twenty-First Century Books. This book was released on 2013-10-01 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experiment: A child is deliberately infected with the deadly smallpox disease without his parents' informed consent. Result: The world's first vaccine. Experiment: A slave woman is forced to undergo more than thirty operations without anesthesia. Result: The beginnings of modern gynecology. Incidents like these paved the way for crucial, lifesaving medical discoveries. But they also harmed and humiliated their test subjects, many of whom did not agree to the experiments in the first place. How do doctors balance the need to test new medicines and procedures with their ethical duty to protect the rights of human subjects? Take a harrowing journey through some of history's greatest medical advances?and its most horrifying medical atrocities?to discover how human suffering has gone hand in hand with medical advancement.
Download or read book Human Medical Experimentation written by Frances R. Frankenburg MD and published by Bloomsbury Publishing USA. This book was released on 2017-01-16 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for students and general readers alike, this encyclopedia covers the history of human medical experimentation, for better and worse, from the time of Hippocrates to the present. Thanks to medical experiments performed on human subjects, we now have vaccines against smallpox, rabies, and polio. Yet the advances that saved lives too often involved the exploitation of vulnerable populations. Covering the history of human medical experimentation from the time of Hippocrates to today, this work will introduce readers to the topic through a mixture of essays and ready-reference materials. The book covers the experiments themselves; the people, companies, and government agencies that carried them out; the relevant medical and sociopolitical background; and the legislation and other protective measures that arose as a result. The encyclopedia is divided chronologically into 6 periods: pre-19th century, the 19th century, the pre-World War II 20th century, the World War II era, the Cold War era, and the post-Cold War period to recent times. Each period begins with an introductory essay and ends with a bibliography. Alphabetically arranged entries in each section cover pertinent people, experiments, and topics. The volume is enriched throughout with a wealth of primary sources, such as physicians' descriptions of their experiments. Medical experiments are not just a thing of the past, and readers will also learn about questions and debates related to contemporary efforts to advance medical science.
Download or read book Against Their Will written by Allen M. Hornblum and published by St. Martin's Press. This book was released on 2013-06-25 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the Cold War, an alliance between American scientists, pharmaceutical companies, and the US military pushed the medical establishment into ethically fraught territory. Doctors and scientists at prestigious institutions were pressured to produce medical advances to compete with the perceived threats coming from the Soviet Union. In Against Their Will, authors Allen Hornblum, Judith Newman, and Gregory Dober reveal the little-known history of unethical and dangerous medical experimentation on children in the United States. Through rare interviews and the personal correspondence of renowned medical investigators, they document how children—both normal and those termed "feebleminded"—from infants to teenagers, became human research subjects in terrifying experiments. They were drafted as "volunteers" to test vaccines, doused with ringworm, subjected to electric shock, and given lobotomies. They were also fed radioactive isotopes and exposed to chemical warfare agents. This groundbreaking book shows how institutional superintendents influenced by eugenics often turned these children over to scientific researchers without a second thought. Based on years of archival work and numerous interviews with both scientific researchers and former test subjects, this is a fascinating and disturbing look at the dark underbelly of American medical history.
Download or read book Doctors from Hell written by Vivien Spitz and published by Sentient Publications. This book was released on 2005 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A chilling story of human depravity and ultimate justice, told for the first time by an eyewitness court reporter for the Nuremberg war crimes trial of Nazi doctors. This is the account of 22 men and 1 woman and the torturing and killing by experiment they authorized in the name of scientific research and patriotism. Doctors from Hell includes trial transcripts that have not been easily available to the general public and previously unpublished photographs used as evidence in the trial. The author describes the experience of being in bombed-out, dangerous, post-war Nuremberg, where she lived for two years while working on the trial. Once a Nazi sympathizer tossed bombs into the dining room of the hotel where she lived moments before she arrived for dinner. She takes us into the courtroom to hear the dramatic testimony and see the reactions of the defendants to the proceedings. This landmark trial resulted in the establishment of the Nuremberg code, which set the guidelines for medical research involving human beings. A significant addition to the literature on World War II and the Holocaust, medical ethics, human rights, and the barbaric depths to which human beings can descend.
Download or read book Experimentation with Human Beings written by Jay Katz and published by Russell Sage Foundation. This book was released on 1972-07-24 with total page 1210 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, increasing concern has been voiced about the nature and extent of human experimentation and its impact on the investigator, subject, science, and society. This casebook represents the first attempt to provide comprehensive materials for studying the human experimentation process. Through case studies from medicine, biology, psychology, sociology, and law—as well as evaluative materials from many other disciplines—Dr. Katz examines the problems raised by human experimentation from the vantage points of each of its major participants—investigator, subject, professions, and state. He analyzes what kinds of authority should be delegated to these participants in the formulation, administration, and review of the human experimentation process. Alternative proposals, from allowing investigators a completely free hand to imposing centralized governmental control, are examined from both theoretical and practical perspectives. The conceptual framework of Experimentation with Human Beings is designed to facilitate not only the analysis of such concepts as "harm," "benefit," and "informed consent," but also the exploration of the problems raised by man's quest for knowledge and mastery, his willingness to risk human life, and his readiness to delegate authority to professionals and rely on their judgment.
Download or read book Subjected to Science written by Susan E. Lederer and published by JHU Press. This book was released on 1997-11-07 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Susan Lederer provides the first full-length history of early biomedical research with human subjects. Lederer offers detailed accounts of experiments conducted on both healthy and unhealthy men, women, and children, during the period from 1890 to 1940, including yellow fever experiments, Udo Wile's "dental drill" experiments on insane patients, and Hideyo Noguchi's syphilis experiments.
Download or read book Medical Apartheid written by Harriet A. Washington and published by Vintage. This book was released on 2008-01-08 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BOOK CRITICS CIRCLE AWARD WINNER • The first full history of Black America’s shocking mistreatment as unwilling and unwitting experimental subjects at the hands of the medical establishment. No one concerned with issues of public health and racial justice can afford not to read this masterful book. "[Washington] has unearthed a shocking amount of information and shaped it into a riveting, carefully documented book." —New York Times From the era of slavery to the present day, starting with the earliest encounters between Black Americans and Western medical researchers and the racist pseudoscience that resulted, Medical Apartheid details the ways both slaves and freedmen were used in hospitals for experiments conducted without their knowledge—a tradition that continues today within some black populations. It reveals how Blacks have historically been prey to grave-robbing as well as unauthorized autopsies and dissections. Moving into the twentieth century, it shows how the pseudoscience of eugenics and social Darwinism was used to justify experimental exploitation and shoddy medical treatment of Blacks. Shocking new details about the government’s notorious Tuskegee experiment are revealed, as are similar, less-well-known medical atrocities conducted by the government, the armed forces, prisons, and private institutions. The product of years of prodigious research into medical journals and experimental reports long undisturbed, Medical Apartheid reveals the hidden underbelly of scientific research and makes possible, for the first time, an understanding of the roots of the African American health deficit. At last, it provides the fullest possible context for comprehending the behavioral fallout that has caused Black Americans to view researchers—and indeed the whole medical establishment—with such deep distrust.
Download or read book Dangerous Medicine written by Sydney A. Halpern and published by Yale University Press. This book was released on 2021-11-23 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: The untold history of America’s mid-twentieth-century program of hepatitis infection research, its scientists’ aspirations, and the damage the project caused human subjects From 1942 through 1972, American biomedical researchers deliberately infected people with hepatitis. Government-sponsored researchers were attempting to discover the basic features of the disease and the viruses causing it, and to develop interventions that would quell recurring outbreaks. Drawing from extensive archival research and in-person interviews, Sydney Halpern traces the hepatitis program from its origins in World War II through its expansion during the initial Cold War years, to its demise in the early 1970s amid an outcry over research abuse. The subjects in hepatitis studies were members of stigmatized groups—conscientious objectors, prison inmates, the mentally ill, and developmentally disabled adults and children. The book reveals how researchers invoked military and scientific imperatives and the rhetoric of a common good to win support for the experiments and access to recruits. Halpern examines the participants’ long-term health consequences and raises troubling questions about hazardous human experiments aimed at controlling today’s epidemic diseases.
Download or read book The Plutonium Files written by Eileen Welsome and published by Delta. This book was released on 2010-10-20 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the vast wartime factories of the Manhattan Project began producing plutonium in quantities never before seen on earth, scientists working on the top-secret bomb-building program grew apprehensive. Fearful that plutonium might cause a cancer epidemic among workers and desperate to learn more about what it could do to the human body, the Manhattan Project's medical doctors embarked upon an experiment in which eighteen unsuspecting patients in hospital wards throughout the country were secretly injected with the cancer-causing substance. Most of these patients would go to their graves without ever knowing what had been done to them. Now, in The Plutonium Files, Pulitzer Prize-winning reporter Eileen Welsome reveals for the first time the breadth of the extraordinary fifty-year cover-up surrounding the plutonium injections, as well as the deceitful nature of thousands of other experiments conducted on American citizens in the postwar years. Welsome's remarkable investigation spans the 1930s to the 1990s and draws upon hundreds of newly declassified documents and other primary sources to disclose this shadowy chapter in American history. She gives a voice to such innocents as Helen Hutchison, a young woman who entered a prenatal clinic in Nashville for a routine checkup and was instead given a radioactive "cocktail" to drink; Gordon Shattuck, one of several boys at a state school for the developmentally disabled in Massachusetts who was fed radioactive oatmeal for breakfast; and Maude Jacobs, a Cincinnati woman suffering from cancer and subjected to an experimental radiation treatment designed to help military planners learn how to win a nuclear war. Welsome also tells the stories of the scientists themselves, many of whom learned the ways of secrecy on the Manhattan Project. Among them are Stafford Warren, a grand figure whose bravado masked a cunning intelligence; Joseph Hamilton, who felt he was immune to the dangers of radiation only to suffer later from a fatal leukemia; and physician Louis Hempelmann, one of the most enthusiastic supporters of the plan to inject humans with potentially carcinogenic doses of plutonium. Hidden discussions of fifty years past are reconstructed here, wherein trusted government officials debated the ethical and legal implications of the experiments, demolishing forever the argument that these studies took place in a less enlightened era. Powered by her groundbreaking reportage and singular narrative gifts, Eileen Welsome has created a work of profound humanity as well as major historical significance. From the Hardcover edition.
Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Download or read book Research on Human Subjects written by Bernard Barber and published by Russell Sage Foundation. This book was released on 1973-03-01 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: How are human subjects treated in biomedical research? What are the expressed standards and self-reported behavior of biomedical researchers in regard to what has sometimes been called their "animal of necessity"? What are some of the determinants of the "strict" and "permissive" patterns which describe the standards and behavior of biomedical researchers? These are the important questions asked and answered in Research on Human Subjects. It is a book based on four years of intensive research. Two studies were completed, one on a nationally representative sample of biomedical research institutions, a second on a sample of 350 researchers who actually use human subjects. In their chapters on "the dilemma of science and therapy," the authors look at the tension between the values of humane therapy and discovery in science. They show that the significant minority of researchers who are "permissive" on the issues of informed consent and a favorable risk-benefit ratio are more likely to be those who are "relative failures" in pursuing the science value. Research on Human Subjects also documents the inadequate training that biomedical researchers get in the ethics of research on human subjects not only in medical schools but in their postgraduate training as well. The medical schools pay relatively more attention to the scientific training of their students than they do to the ethical training that should be its essential complement. The local peer review groups that screen research on human subjects in the institutions where it is carried on are another central focus of attention of the research and analysis reported in this book. The peer review groups do a fairly good job but, the authors show, there are various conditions of their relative efficacy which are not met by review groups in many important research institutions. The medical school review groups, for example, have not been outstanding performers with respect to the several conditions of relative efficacy. In the concluding chapter, the authors discuss the general problem of the social responsibilities of powerful professions and make very specific suggestions for policy change and reform for the biomedical research profession and its use of human subjects.
Download or read book Human Medical Experimentation written by Frances R. Frankenburg MD and published by Bloomsbury Publishing PLC. This book was released on 2024-01-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for students and general readers alike, this encyclopedia covers the history of human medical experimentation, for better and worse, from the time of Hippocrates to the present. Thanks to medical experiments performed on human subjects, we now have vaccines against smallpox, rabies, and polio. Yet the advances that saved lives too often involved the exploitation of vulnerable populations. Covering the history of human medical experimentation from the time of Hippocrates to today, this work will introduce readers to the topic through a mixture of essays and ready-reference materials. The book covers the experiments themselves; the people, companies, and government agencies that carried them out; the relevant medical and sociopolitical background; and the legislation and other protective measures that arose as a result. The encyclopedia is divided chronologically into six periods: pre-19th century, the 19th century, the pre-World War II 20th century, the World War II era, the Cold War era, and the post-Cold War period to today. Each period begins with an introductory essay and ends with a bibliography. Alphabetically arranged entries in each section cover pertinent people, experiments, and topics. The volume is enriched throughout with a wealth of primary sources, such as physicians' descriptions of their experiments. Medical experiments are not just a thing of the past, and readers will also learn about questions and debates related to contemporary efforts to advance medical science.
Download or read book Undue Risk written by Jonathan D. Moreno and published by Psychology Press. This book was released on 2001 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring the history of the use of human subjects in atomic, biological, and chemical warfare by the U. S. Government, the author reveals details and exposes policies and specific cases on this practice.
Download or read book The Belmont Report written by United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research and published by . This book was released on 1978 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.
Download or read book The Ethics of Research with Human Subjects written by David B. Resnik and published by Springer. This book was released on 2018-01-09 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a framework for approaching ethical and policy dilemmas in research with human subjects from the perspective of trust. It explains how trust is important not only between investigators and subjects but also between and among other stakeholders involved in the research enterprise, including research staff, sponsors, institutions, communities, oversight committees, government agencies, and the general public. The book argues that trust should be viewed as a distinct ethical principle for research with human subjects that complements other principles, such as autonomy, beneficence, non-maleficence, and justice. The book applies the principle of trust to numerous issues, including informed consent, confidentiality, risk minimization, risks and benefits, protection of vulnerable subjects, experimental design, research integrity, and research oversight.This work also includes discussions of the history of research involving human subjects, moral theories and principles, contemporary cases, and proposed regulatory reforms. The book is useful for undergraduate and graduate students studying ethical policy issues related to research with human subjects, as well as for scientists and scholars who are interested in thinking about this topic from the perspective of trust.
Download or read book Mind Wars written by Jonathan D. Moreno and published by Bellevue Literary Press. This book was released on 2012-05-01 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: “One of the most important thinkers describes the literally mind-boggling possibilities that modern brain science could present for national security.” —LAWRENCE J. KORB, former US Assistant Secretary of Defense “Fascinating and frightening.” —Bulletin of the Atomic Scientists The first book of its kind, Mind Wars covers the ethical dilemmas and bizarre history of cutting-edge technology and neuroscience developed for military applications. As the author discusses the innovative Defense Advanced Research Projects Agency (DARPA) and the role of the intelligence community and countless university science departments in preparing the military and intelligence services for the twenty-first century, he also charts the future of national security. Fully updated and revised, this edition features new material on deep brain stimulation, neuro hormones, and enhanced interrogation. With in-depth discussions of “psyops” mind control experiments, drugs that erase both fear and the need to sleep, microchip brain implants and advanced prosthetics, supersoldiers and robot armies, Mind Wars may read like science fiction or the latest conspiracy thriller, but its subjects are very real and changing the course of modern warfare. Jonathan D. Moreno has been a senior staff member for three presidential advisory commissions and has served on a number of Pentagon advisory committees. He is an ethics professor at the University of Pennsylvania and the editor-in-chief of the Center for American Progress’ online magazine Science Progress.
