Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1993 with total page 1488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genetic Mapping and DNA Sequencing written by Terry Speed and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics mapping, physical mapping and DNA sequencing are the three key components of the human and other genome projects. Statistics, mathematics and computing play important roles in all three, as well as in the uses to which the mapping and sequencing data are put. This volume edited by key researchers Mike Waterman and Terry Speed reviews recent progress in the area, with an emphasis on the theory and application of genetic mapping.

Download or read book Human Genetics and Genomics Includes Wiley E Text written by Bruce R. Korf and published by John Wiley & Sons. This book was released on 2013-02-11 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions. A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice. Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today’s genetics teaching, and includes updated discussion of genetic risk assessment, “single gene” disorders and therapeutics. Key learning features include: Clinical snapshots to help relate science to practice 'Hot topics' boxes that focus on the latest developments in testing, assessment and treatment 'Ethical issues' boxes to prompt further thought and discussion on the implications of genetic developments 'Sources of information' boxes to assist with the practicalities of clinical research and information provision Self-assessment review questions in each chapter Accompanied by the Wiley E-Text digital edition (included in the price of the book), Human Genetics and Genomics is also fully supported by a suite of online resources at www.korfgenetics.com, including: Factsheets on 100 genetic disorders, ideal for study and exam preparation Interactive Multiple Choice Questions (MCQs) with feedback on all answers Links to online resources for further study Figures from the book available as PowerPoint slides, ideal for teaching purposes The perfect companion to the genetics component of both problem-based learning and integrated medical courses, Human Genetics and Genomics presents the ideal balance between the bio-molecular basis of genetics and clinical cases, and provides an invaluable overview for anyone wishing to engage with this fast-moving discipline.

Download or read book ICRF Handbook of Genome Analysis written by N. S. Spurr and published by John Wiley & Sons. This book was released on 2009-06-03 with total page 1038 pages. Available in PDF, EPUB and Kindle. Book excerpt: The combined power of genetic analysis and recombinant DNA technology to analyse entire genomes has moved biomedical research into a new and revolutionary phase. The complete sequencing and mapping of the human genome, as well as the genomes of other model organisms, will be the basis for our future understanding of human disease, and will allow us to answer fundamental questions about development and evolution. T The new ICRF Handbook of Genome Analysis is the essential guide to the enormous range of techniques available to the researcher for both the genetic and physical mapping of the genome, as well as the sequencing and analysis of DNA. It is both a protocol manual and a comprehensive information resource. Written by international experts, each chapter presents a state-of-the-art review of a methodology. Methods are fully described and evaluated; their advantages and disadvantages discussed; and their suitability for different investigations considered. Step-by-step protocols, including computer analyses, are given for 123 essential experimental procedures. 'Troubleshooting' sections discuss possible reasons for failure and offer remedies. The primary focus is on human genetics and the benefits of an understanding of the genome for the diagnosis and treatment of human disease. The book also considers the current state of progress in the analysis of genomes of many model organisms, including plants. A major part of the work provides detail on Internet resources as well as basic data on human and other genomes, including mapped disease genes and mouse knockouts. Covers not only the human genome in relation to cancers and other human diseases, but also the genomes of all important model organisms Contains 123 easy-to-follow protocols for essential experimental procedures Reviews a vast range of other information resources, including journals and the Internet * provides an invaluable listing of suppliers of laboratory materials Has been written by international experts from their own practical experience Is mandated by the Imperial Cancer Research Fund - a leader in research in this field Has a sturdy spiral binding within a hardback case for ease of use in the lab

Download or read book Human Genome News written by and published by . This book was released on 1989 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genetic Analysis written by Philip Mark Meneely and published by Oxford University Press, USA. This book was released on 2014 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: It uses extended case studies and text boxes to augment the narrative, taking the reader right to the forefront of contemporary research, without losing clarity of explanation and insight.

Download or read book Schizophrenia Bulletin written by and published by . This book was released on 1989 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in Molecular Pathology E Book 2021 written by Gregory J. Tsongalis and published by Elsevier Health Sciences. This book was released on 2021-10-13 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Molecular Pathology is an annual review publication that covers the current practices and latest developments in the field of Molecular Pathology. Each issue is divided into sections for comprehensive coverage of all subspecialty areas within molecular pathology, including, Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid Tumors, and special topics on COVID-19. The Editor-in-Chief of the publication is Dr. Gregory Tsongalis, a leading expert in the field. Topics covered this year include but are not limited to: Phenotype Association and Variant Pathogenicity Prediction Tools in Genomic Analysis; The application of noninvasive prenatal screening to detect copy number variations; Next generation cytogenomics using optical mapping; Review of molecular in APL; NGS for MRD in acute leukemia; Review of emerging technologies as they pertain to infectious disease testing; Germline genetic variants that predict drug response; Nutrigenomics; PGx of hypertension; Genomic data for blood typing, specifically both through NGS and arrays; Preanalytic Variables and Tissue Stewardship for Reliable Next-Generation Sequencing (NGS) Clinical Analysis; and Cell-free nucleic acids in cancer: Current approaches, challenges, and future directions.

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1938 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Download or read book Cloning written by Stephen D. Fairbanks and published by Nova Publishers. This book was released on 2004 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The terms 'recombinant DNA technology', 'DNA cloning', 'molecular cloning' or 'gene cloning' all refer to the same process: the transfer of a DNA fragment of interest from one organism to a self-replicating genetic element such as a bacterial plasmid. The DNA of interest can then be propagated in a foreign host cell. This technology has been around since the 1970s, and it has become a common practice in molecular biology labs today. Reproductive cloning is a technology used to generate an animal that has the same nuclear DNA as another currently or previously existing animal. Dolly was created by reproductive cloning technology. In a process called 'somatic cell nuclear transfer' (SCNT), scientists transfer genetic material from the nucleus of a donor adult cell to an egg whose nucleus, and thus its genetic material, has been removed. The reconstructed egg containing the DNA from a donor cell must be treated with chemicals or electric current in order to stimulate cell division. Once the cloned embryo reaches a suitable stage, it is transferred to the uterus of a female host where it continues to develop until birth. Therapeutic cloning, also called "embryo cloning," is the production of human embryos for use in research. The goal of this process is not to create cloned human beings, but rather to harvest stem cells that can be used to study human development and to treat disease. Stem cells are important to biomedical researchers because they can be used to generate virtually any type of specialised cell in the human body. This new book presents an up-to-date Chronology of Cloning along with current and selected abstracts dealing with cloning as well as a guide to books on the topic. Access to the abstract and books sections is provided by title, subject and author indexes.

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1983 with total page 1442 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Download or read book Methods in Nucleic Acids Research written by Gregory W. Warr and published by CRC Press. This book was released on 1990-11-26 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Nucleic Acids Research provides extensively referenced overviews of chapter topics, in addition to step-by-step laboratory protocols. Topics include discussions regarding the preparation and assay of antibodies against oligopeptides, RNA footprinting, gel-retardation assays for nucleic acid binding proteins, in vitro transcription and translation assays for studies of eukaryotic gene expression, human genome mapping, forensic analysis of DNA polymorphism, in situ hybridization for the detection of specific RNA, and other methods. Biochemists, molecular biologists, immunologists, cell biologists, and geneticists will find this book invaluable for their research.

Download or read book Pediatric Allergy E Book written by Donald Y. M. Leung and published by Elsevier Health Sciences. This book was released on 2020-10-19 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: With complete, concise coverage of prevention, indications, diagnosis, and treatment, Pediatric Allergy, 4th Edition, is your go-to resource for current, clinically-focused content in the rapidly changing field of allergies and immune-mediated diseases in children. This highly regarded reference fully covers immunology and origins of allergy, growth and development, pregnancy, infancy, and early, middle, and late childhood—all with a new, practical, clinical focus. You'll find authoritative coverage of the full range of allergies in pediatric patients, from asthma and other common conditions to rare or uncommon allergies, providing a one-stop resource for clinicians across specialties who care for children. - Focuses on the clinical application of science to the bedside, including clinical pearls discussing best practice approaches and guidelines. - Integrates the latest research on the origins of allergy in early life, including pregnancy, the neonate, and infants. - Includes new, evidence-based management guidelines for various diseases, including food allergy, atopic dermatitis, asthma and immunodeficiency. - Provides new content on the prevention of allergies; asthma, eczema, and food allergies in young children; and extensive current guidelines and new therapies. - Offers up-to-date information on key areas such as food challenges, skin testing, IgE diagnostic labs, immunotherapy, clinical immunology diagnostic testing, molecular diagnostics, and lung function testing. - Highlights current guidance from a new team of leading experts with 150 anatomic schematics, clinical photos, and algorithms—many new to this edition. - Covers gene therapy, stem-cell therapy, and a host of immunodeficiency diseases found in children with allergies. - Discusses targeted biologics for severe allergic diseases, defects of innate immunity, rheumatic diseases of childhood, and inflammatory disorders. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Download or read book Guide to Human Genome Computing written by Martin J. Bishop and published by Academic Press. This book was released on 1998-03-25 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Guide to Human Genome Computing is invaluable to scientists who wish to make use of the powerful computing tools now available to assist them in the field of human genome analysis. This book clearly explains access and use of sequence databases, and presents the various computer packages used to analyze DNA sequences, measure linkage analysis, compare and align DNA sequences from different genes or organisms, and infer structural and functional information about proteins from sequence data. This Second Edition contains completely updated material. Rather than a revision of the previous volume, the Second Edition is essentially a new book, based on the subjects which will be of interest over the coming years. This new book is international, both in scope and authorship. - Computing resources for the following are clearly explained: Internet resources - databases etc. - Genetic analysis - Sib-pair studies - Comparative mapping - Radiation hybrids - Sequence ready clone maps - Human genome sequencing - ESTs - Gene prediction - Gene expression

Download or read book Human Blood Groups written by Geoff Daniels and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Blood Groups is a comprehensive and fully referenced textcovering scientific and clinical aspects of red cell surfaceantigens, including: serology inheritance biochemistry molecular genetics biological functions clinical significance in transfusion medicine Over a century has passed since Landsteiner discovered the humanblood groups, making the practice of blood transfusion possible.Yet, in the six years since the first edition of Human Blood Groupswas published, new blood groups have been discovered, several bloodgroup genes have been cloned, and the molecular backgrounds ofnumerous blood group variants have been worked out. All this newinformation has made the production of a second edition of HumanBlood Groups timely. This book is an essential reference source for all those workingin the field of blood transfusion and blood banking.

Download or read book Published Scientific Papers of the National Institutes of Health written by National Institutes of Health (U.S.). and published by . This book was released on 1990 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the broad outline of NIH organizational structure, theprofessional staff, and their scientific and technical publications covering work done at NIH.