Download or read book Host Interactions in HIV Infection written by Chris Stinson and published by . This book was released on 2015-03-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is no vaccine or cure available for HIV; hence it is a promintent global health threat. To beat the challenges of HIV/AIDS, one must have sufficient knowledge of HIV infection. This book discusses various forms of HIV-host interactions in vitro and in vivo, like the interrelation between cellular components and HIV proteins. Integrase, Tat, and Nef, as well as the clinical pertinence of HIV superinfection. The book also examines the function of innate immunity along with dendritic cells and defensins in HIV infections and the effects of host factors on HIV pathogenesis. Topics like co-infection are also included that talk about the influence of Human herpesvirus 6 and Trichomonas vaginalis on HIV infection. The book also includes a discussion on the generations of HIV molecular clones that can be applied in macaques and the potential usage of cotton rats for HIV studies.
Download or read book HIV Host Interactions written by Theresa Li-Yun Chang and published by BoD – Books on Demand. This book was released on 2011-11-02 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV remains the major global health threat, and neither vaccine nor cure is available. Increasing our knowledge on HIV infection will help overcome the challenge of HIV/AIDS. This book covers several aspects of HIV-host interactions in vitro and in vivo. The first section covers the interaction between cellular components and HIV proteins, Integrase, Tat, and Nef. It also discusses the clinical relevance of HIV superinfection. The next two chapters focus on the role of innate immunity including dendritic cells and defensins in HIV infection followed by the section on the impact of host factors on HIV pathogenesis. The section of co-infection includes the impact of Human herpesvirus 6 and Trichomonas vaginalis on HIV infection. The final section focuses on generation of HIV molecular clones that can be used in macaques and the potential use of cotton rats for HIV studies.
Download or read book Direct and Indirect Interactions of HIV With Host Cells written by Tetsuo Tsukamoto and published by Frontiers Media SA. This book was released on 2021-12-06 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book HIV Host Interactions written by Theresa Li-Yun Chang and published by IntechOpen. This book was released on 2011-11-02 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV remains the major global health threat, and neither vaccine nor cure is available. Increasing our knowledge on HIV infection will help overcome the challenge of HIV/AIDS. This book covers several aspects of HIV-host interactions in vitro and in vivo. The first section covers the interaction between cellular components and HIV proteins, Integrase, Tat, and Nef. It also discusses the clinical relevance of HIV superinfection. The next two chapters focus on the role of innate immunity including dendritic cells and defensins in HIV infection followed by the section on the impact of host factors on HIV pathogenesis. The section of co-infection includes the impact of Human herpesvirus 6 and Trichomonas vaginalis on HIV infection. The final section focuses on generation of HIV molecular clones that can be used in macaques and the potential use of cotton rats for HIV studies.
Download or read book Virus host Interactions in Early HIV 1 Infection written by Joanna Ceinwen Rowley and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book HIV Interactions with Dendritic Cells written by Li Wu and published by Springer Science & Business Media. This book was released on 2012-09-11 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given rapid research progress and advance of the techniques in studying HIV interactions with host cells and factors, there is a critical need for a book on HIV interactions with DCs. The proposed book will aim for a broad readership to facilitate HIV/AIDS research and provide a practical tool for HIV researchers to continuously address novel questions. Specifically, the editors will summarize the literature in this field and provide critical analysis and future directions. International researchers will be invited as contributors of the book, highlighting authors who have contributed significantly to the field from different angles and aspects of virology, cell biology and immunology, etc.
Download or read book Virus host Interactions in Early HIV 1 Infection written by and published by . This book was released on 2015 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Virus host Interaction in HIV Infection written by Matthijs Tersmette and published by . This book was released on 1989 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book HIV and the Pathogenesis of AIDS written by Jay A. Levy and published by . This book was released on 1994 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Virus host Interaction written by Jingyou Yu and published by . This book was released on 2018 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Chapter five of this dissertation, I showed that LY6E showed a distinct phenotype in low-CD4-expresisng Jurkat cells, i.e., LY6E inhibits HIV-1 entry by downregulating CD4. LY6E was found to be co-localized with CD4 on plasma membranes and further down-modulated CD4 on cell surface; this leads to compromised viral binding and subsequent viral entry. Ectopic expression of CD4 was able to rescue the phenotype of LY6E in Jurkat cells. The CD4 dependent inhibitory phenotype of LY6E can be recapitulated in low-CD4 primary cells human Monocyte-derived macrophages (MDMs). Taken together, this study reveals that LY6E likely modulates HIV-1 infection in a cell type dependent manner, and the CD4 surface expression level determines the sensitivity of HIV to LY6E. Overall, in this thesis work, I have investigated the role of IFITMs and LY6E in HIV-1 infection and discovered some multifaceted functions of these two families of proteins in modulating the different stages of the viral life cycle. My data highlight the more complex functions of type I IFNs and ISGs in HIV infection and AIDS pathogenesis. Information obtained in this thesis provides insights into understanding of the modes of action of type I IFNs and virus-host interaction in general, and could have therapeutic implications for prevention and treatment of HIV/AIDS.
Download or read book HIV Interactions with Host Cell Proteins written by Paul Spearman and published by Springer Science & Business Media. This book was released on 2009-12-11 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of viruses necessarily involves dissecting the intimate details of cellular pathways. Viruses have often been employed as tools in studying cellular pathways, as was done by early retrovirologists such as Peyton Rous in attempting to understand the mechanism of cellular transformation and oncogenesis. On the other side of the coin, virologists seek to de?ne those cellular elements interacting intimatelywiththeir virus ofinterestinorder to better understand viral replication itself, and in some cases to develop antiviral strategies. It is in the intersection of virology and cell biology that many of us ?nd the most rewarding aspects of our research. When a new discovery yields insights into basic cellular mechanisms and presents new targets for int- vention to ?ght a serious pathogen, the impact can be high and the excitement intense. HIV has been no exception to the rule that viruses reveal many basic aspects of cellular biology. In recent years, in part because of the importance of HIV as a major cause of human suffering, numerous cellular processes have been elucidated through work on processes or proteins of this human retrovirus. The excitement in this ?eld is especially well illustrated by the discovery of new innate means of resisting viral replication, such as the work on APOBEC3G, TRIM5a, and BST-2/ tetherin presented in this volume.
Download or read book HIV written by Frederic Bushman and published by Cold Spring Harbor Perspective. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basic biology of the HIV virus provides a model for a more general understanding of retroviruses, and the worldwide epidemic of AIDS makes research into the disease process and potential therapies among the most critical in biomedical science. This book explores work on the molecular biology of HIV, host-virus interactions, host immune responses, HIV transmission, and more.
Download or read book HIV and the New Viruses written by Angus G. Dalgleish and published by Elsevier. This book was released on 1999-03-16 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV and the New Viruses presents cutting-edge reviews of persistent human virus infections as a coherent collection for the first time. These cover recently discovered viruses such as HHV-6, HHV-8 and HCV, as well as the latest research on HIV. This comprehensive and updated reference includes an in-depth study of the major issues in the epidemiology, pathogenicity, molecular virology, host responses and management of conditions associated with those viruses. Information on new pharmaceuticals and vaccine developments is also included. Edited by the leading experts in the field, HIV and the New Viruses will be essential reading for postgraduates, clinicians and researchers in virology, immunology, cancer, molecular biology and the pharmaceutical industry. - Presents cutting-edge reviews of persistent human virus infections as a coherent collection for the first time - Includes an in-depth study of the major issues in the epidemiology, pathogenicity, molecular virology, host responses, and management of conditions associated with those viruses
Download or read book HIV Host Interactions written by Theresa Li-Yun Chang and published by IntechOpen. This book was released on 2011-11-02 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV remains the major global health threat, and neither vaccine nor cure is available. Increasing our knowledge on HIV infection will help overcome the challenge of HIV/AIDS. This book covers several aspects of HIV-host interactions in vitro and in vivo. The first section covers the interaction between cellular components and HIV proteins, Integrase, Tat, and Nef. It also discusses the clinical relevance of HIV superinfection. The next two chapters focus on the role of innate immunity including dendritic cells and defensins in HIV infection followed by the section on the impact of host factors on HIV pathogenesis. The section of co-infection includes the impact of Human herpesvirus 6 and Trichomonas vaginalis on HIV infection. The final section focuses on generation of HIV molecular clones that can be used in macaques and the potential use of cotton rats for HIV studies.
Download or read book Clinical Approach to Infection in the Compromised Host written by Robert H. Rubin and published by Springer. This book was released on 2013-11-11 with total page 777 pages. Available in PDF, EPUB and Kindle. Book excerpt: `With admirable clarity the authors-all highly regarded experts in their respective fields-present the clinician with a supremely readable and practical text. The emphasis here is pragmatic, although there is sufficient pathogenesis and physiology to provide a fine balance.'-Journal of the American Medical Association, from a review of the second edition. This updated and profusely illustrated edition is 75% larger than its first incarnation. New coverage includes transplantation medicine, AIDS, patient management, and host-parasite interactions.
Download or read book Virus Host Interactions written by Marilena Aquino de Muro and published by Springer Nature. This book was released on 2022-12-19 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume spotlights methods to investigate a variety of virus-host interactions in humans, other mammals, fish, or insects. It explores viruses such as white spot syndrome virus (WSSV), honeybee viruses, Nipah virus, EBV, SVCV, HSV-1, HIV-1, A H1N1, and SARS-CoV-2, as well as applications of techniques such as qPCR, serum antibody responses, 4C analysis, cell membrane fusion, biosensors, computational modelling, quantitative proteomics, and other genetic tools to decipher those viral infections and interactions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Virus-Host Interactions: Methods and Protocols serves as a valuable resource for researchers both in academia and in the biosciences industry who are engaged in the search for a better understanding of threatening virus-hosts interactions, virus detection, their characterization, and ultimately their taming and control.
