Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Download or read book Signal Transduction in Cancer written by David A. Frank and published by Springer Science & Business Media. This book was released on 2002-12-31 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."

Download or read book RNA Tumor Viruses Supplements and appendixes written by and published by . This book was released on 1984 with total page 1254 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Oxford Textbook of Oncology written by David J. Kerr and published by Oxford University Press. This book was released on 2016-01-28 with total page 2837 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and edited by internationally recognised leaders in the field, the new edition of the Oxford Textbook of Oncology has been fully revised and updated, taking into consideration the advancements in each of the major therapeutic areas, and representing the multidisciplinary management of cancer. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.

Download or read book Oncogenes and Growth Factors written by Ralph A. Bradshaw and published by Elsevier Science & Technology. This book was released on 1987 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Hormones Growth Factors Oncogenes written by Enrique Pimentel and published by CRC Press. This book was released on 1987-06-30 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text examines the hormones and peptide growth factors involved in the regulation of metabolism, growth and differentiation in metazoan organisms and proto-oncogene expression. Investigates protein products of some proto-oncogenes for involvement in the transductional and post-transductional and mechanisms of hormones and peptide growth factors.

Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

Download or read book Hormone Signaling written by Vincent Goffin and published by Springer Science & Business Media. This book was released on 2002-03-31 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multicellular organisms require a means of intracellular communication to organize and develop the complex body plan that occurs during embryogenesis and then for cell and organ systems to access and respond to an ever changing environmental milieu. Mediators of this constant exchange of information are growth factors, neurotransmmitters, peptide and protein hormones which bind to cell surface receptors and transduce their signals from the extracellular space to the intracellular compartment. Via multiple signaling pathways, receptors of this general class affect growth, development and differentiation. Smaller hydrophobic signaling molecules, such as steroids and non-steroid hormones, vitamins and metabolic mediators interact with a large family of nuclear receptors. These receptors function as transcription factors affecting gene expression, to regulate the multiple aspects of animal and human physiology, including development, reproduction and homeostasis. The aim of this book is to cover various aspects of intracellular signaling involving hormone receptors.

Download or read book Growth Factors and Oncogenes written by M. Bolla and published by . This book was released on 1989 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major objective of this book is to bring together specialists well-known for their contribution to the basic knowledge of growth factors and oncogenes and experts engaged in clinical research and prospective in cancer therapy."

Download or read book Handbook of Neuroendocrinology written by George Fink and published by Academic Press. This book was released on 2012 with total page 895 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.

Download or read book Hormones written by Etienne-Emile Baulieu (ed) and published by Springer Science & Business Media. This book was released on 1990-11-30 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrinology is a field in which enormous advances have been made in the last decade; the rate of discovery of new hormones, hormone-like molecules, receptors, and mechanisms of action is continually advancing. The development of techniques in immunology and molecular biology has led to the possibility of describing in detail the gene structure of many of the compounds involved in hormonal systems. Remarkable homology has been shown between oncogene products and various components of the endocrine network, leading to the asser tion that deregulation of hormonal function is involved in the generation and/or development of cancer. We now know that the central nervous system is both a target and a production site of many hormonal products, and that hormones, neurotransmitters, growth factors and immunopeptides all act through similar mechanisms. The only second messenger known ten years ago was cAMP; today calcium, derivatives of membrane phospholipids, and protein kinases are also known to be mediators of hormone action. The very concept of hormonal systems has been expanded to include not only endocrine secretions but also para- and autohormones and their mechanisms of action; an understanding of their functions will be central to the immediate future of medicine. The discovery of hormonal molecules and endocrine interactions and the subsequent understanding of hormone related pathophysiology has led to the development of new strategies in medical treatment such as fertility control and the management of diabetes.

Download or read book Molecular Targeting and Signal Transduction written by Rakesh Kumar and published by Springer Science & Business Media. This book was released on 2004-04-30 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our limited understanding of cellular regulatory signal-transduction-networks has been a barrier to progress in improving the overall cure-rate of human cancers. Delineation of the physiologic roles of the specific regulatory signaling components, with known association with metastatic phenotypes, is a highly promising area which will likely provide the next generation of targeted strategies in the future of molecular cancer medicine. These signaling components are likely to be used in diagnosis, prognosis, and as novel targets for therapeutic development. This book brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation. It is directed at clinicians and scientists working in the areas of experimental and molecular therapeutics, molecular medicine, translational cancer research, and bio-medical sciences in general.

Download or read book Control of Gene Expression by Catecholamines and the Renin Angiotensin System written by Heinz Rupp and published by Springer Science & Business Media. This book was released on 2000-11-30 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The special issue of Molecular and Cellular Biochemistry focuses on `Control of Gene Expression by Catecholamines and the Renin-Angiotensin System' in health and disease. In recent years, great progress has been made in the understanding of catecholamine and angiotensin II modulated gene expression. There is also increasing evidence that catecholamine and angiotensin II induced cellular injury not solely arises from classical pathways but also from a perturbed gene expression. Taking into account that catecholamines and angiotensin II are vital for a balanced gene expression of many cells, the intriguing possibility arises that various disease are initiated or aggravated by such an imbalance. Catecholamine and angiotensin II influences can be in excess arising from, for example, hypercaloric food intake or psychosocial stress. During early progression of heart failure, sympathetic activity and angiotensin II influences also become increased. Due to beta-adrenergic receptor downregulation, depressed catecholamine influences are expected in the final stage of heart failure. An imbalanced influence of catecholamines and angiotensin II on gene expression leads to disordered molecular structures of the cell and an impaired cell function. This focused issue is organized into chapters concentrating on catecholamines, angiotensin II, and the interaction between catecholamines and angiotensin II. Basic biochemical processes are covered in detail and the potential of these pathways for explaining chronic diseases associated with excess catecholamine and angiotensin II influences should become apparent. It is hoped that this focussed issue triggers novel research into the development of drugs that are targeted at diseases characterized by an imbalanced gene expression involving catecholamines and angiotensin II.

Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Hormonal Regulation of Growth written by Herwig Frisch and published by . This book was released on 1989 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Aging and Health written by Anatoli I. Yashin and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging. Finally, the book presents an outlook for the development of interventions to delay or to reverse the features of aging. The publication is recommended to students, researchers as well as professionals dealing with public health and public policy related to an aging society.

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: