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Book The Cerebral Circulation

    Book Details:
  • Author : Marilyn J. Cipolla
  • Publisher : Biota Publishing
  • Release : 2016-07-28
  • ISBN : 1615047239
  • Pages : 82 pages

Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.

Book Pediatric Hypertension

    Book Details:
  • Author : Joseph Flynn
  • Publisher : Springer Science & Business Media
  • Release : 2013-06-26
  • ISBN : 1627034900
  • Pages : 597 pages

Download or read book Pediatric Hypertension written by Joseph Flynn and published by Springer Science & Business Media. This book was released on 2013-06-26 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of pediatric hypertension has undergone important changes in the time since the second edition of Pediatric Hypertension published. Much new information on hypertension in the young has become available. Previous chapters have been fully revised and new chapters have been added to cover important topics of recent interest such as consensus recommendations, the prevalence of hypertension in the young due to the obesity epidemic, studies of antihypertensive agents, and ambulatory blood pressure monitoring. Pediatric Hypertension, Third Edition is a comprehensive volume featuring 38 chapters covering the breadth of the current knowledge. It is divided into four sections: Regulation of Blood Pressure in Children; Assessment of Blood Pressure in Children: Measurement, Normative Data, Epidemiology; and Hypertension in Children: Predictors, Risk Factors, and Special Populations; Evaluation and Management of Pediatric Hypertension. Filled with the most up-to-date information, Pediatric Hypertension, Third Edition is an invaluable resource for clinicians and researchers interested in childhood hypertension.

Book Principles of Endocrinology and Hormone Action

Download or read book Principles of Endocrinology and Hormone Action written by Antonino Belfiore and published by Springer. This book was released on 2018-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.

Book ABC of Hypertension

    Book Details:
  • Author : D. Gareth Beevers
  • Publisher : John Wiley & Sons
  • Release : 2010-07-15
  • ISBN : 1405171359
  • Pages : 89 pages

Download or read book ABC of Hypertension written by D. Gareth Beevers and published by John Wiley & Sons. This book was released on 2010-07-15 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertension is a condition which affects millions of peopleworldwide and its treatment greatly reduces the risk of strokes andheart attacks. This fully revised and updated edition of the ABCof Hypertension is an established guide providing all thenon-specialist needs to know about the measurement of bloodpressure and the investigation and management of hypertensivepatients. This new edition provides comprehensively updated andrevised information on how and whom to treat. The ABC of Hypertension will prove invaluable to generalpractitioners who may be screening large numbers of patients forhypertension, as well as nurse practitioners, midwives and otherhealthcare professionals.

Book Vascular Medicine  A Companion to Braunwald s Heart Disease

Download or read book Vascular Medicine A Companion to Braunwald s Heart Disease written by Mark Creager and published by Elsevier Health Sciences. This book was released on 2019-05-22 with total page 963 pages. Available in PDF, EPUB and Kindle. Book excerpt: With authoritative coverage of everything from recent discoveries in the field of vascular biology to recent clinical trials and evidence-based treatment strategies, Vascular Medicine, 3rd Edition, is your go-to resource for improving your patients’ cardiovascular health. Part of the Braunwald family of renowned cardiology references, this updated volume integrates a contemporary understanding of vascular biology with a thorough review of clinical vascular diseases, making it an ideal reference for vascular medicine specialists, general cardiologists, interventional cardiologists, vascular surgeons, and interventional radiologists. Incorporates technologic advances in vascular imaging – including ultrasound, MRI, CTA, and catheter-based angiography – along with more than 230 new figures, providing an up-to-date and complete view of the vascular system and vascular diseases. Covers novel antithrombotic therapies for peripheral artery disease and venous thromboemboism, advances in endovascular interventions for aortic aneurysms, and today’s best surgical treatments for vascular diseases. Includes seven new chapters: Pathobiology of Aortic Aneurysms; Pathobiology and Assessment of Cardiovascular Fibrosis; Large Vessel Vasculitis; Medium and Small Vessel Vasculitis; Epidemiology and Prognosis of Venous Thromboembolic Disease; Fibromuscular Dysplasia; and Dermatologic Manifestations of Vascular Disease. Discusses methods for aggressive patient management and disease prevention to ensure minimal risk of further cardiovascular problems. Keeps you current with ACC/AHA and ECC guidelines and the best ways to implement them in clinical practice.

Book Endocrine Mechanisms in Hypertension

Download or read book Endocrine Mechanisms in Hypertension written by John H. Laragh and published by Lippincott Williams & Wilkins. This book was released on 1989 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Endocrine Hypertension

Download or read book Endocrine Hypertension written by Karel Pacak and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several genetic, biochemical and radiologic discoveries have impacted the management of endocrine hypertension, while surgical procedures have revolutionized treatment of patients with endocrine hypertension. This text contains the proceedings of a 2001 workshop on the topic.

Book Arterial Hypertension

    Book Details:
  • Author : J. Rosenthal
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 1461256577
  • Pages : 536 pages

Download or read book Arterial Hypertension written by J. Rosenthal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been a little more than half a century since serious, organized research on hyper tension began. Public and even physician interest in the subject remained minimal until the early forties, and even then there were not more than a dozen "fulltime" investigators worldwide. The first organization devoted to communicating regularly the results of hy pertension research was created in Cleveland in 1945; it became the Council for High Blood Pressure Research of the American Heart Association in 1949. The early history of hypertension is not a story of progressive achievement. Richard Bright is given great credit, followed by Mahomed, Allbutt, Riva-Rocci, Bergman and Janeway, but it was not until Volhard, Fahr and Allen that some semblance of order emerged. They were followed by a younger, much more vigorous group of investigators who in fact initiated modern research in hypertension. Two more generations have fol lowed. In the course of some fifty years, we have seen emerge a magnificent body of evidence that has prescribed good treatment and contributed a considerable understanding of the many complex mechanisms involved in the hypertensions. Treatment is now actively pro moted by public health agencies, including the World Health Organization. This is an other case of treatment preceding full understanding of the nature of the disease.

Book Ross   Wilson Anatomy and Physiology in Health and Illness E Book

Download or read book Ross Wilson Anatomy and Physiology in Health and Illness E Book written by Anne Waugh and published by Elsevier Health Sciences. This book was released on 2018-07-12 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of the hugely successful Ross and Wilson Anatomy & Physiology in Health and Illness continues to bring its readers the core essentials of human biology presented in a clear and straightforward manner. Fully updated throughout, the book now comes with enhanced learning features including helpful revision questions and an all new art programme to help make learning even easier. The 13th edition retains its popular website, which contains a wide range of ‘critical thinking’ exercises as well as new animations, an audio-glossary, the unique Body Spectrum© online colouring and self-test program, and helpful weblinks. Ross and Wilson Anatomy & Physiology in Health and Illness will be of particular help to readers new to the subject area, those returning to study after a period of absence, and for anyone whose first language isn’t English. Latest edition of the world’s most popular textbook on basic human anatomy and physiology with over 1.5 million copies sold worldwide Clear, no nonsense writing style helps make learning easy Accompanying website contains animations, audio-glossary, case studies and other self-assessment material, the unique Body Spectrum© online colouring and self-test software, and helpful weblinks Includes basic pathology and pathophysiology of important diseases and disorders Contains helpful learning features such as Learning Outcomes boxes, colour coding and design icons together with a stunning illustration and photography collection Contains clear explanations of common prefixes, suffixes and roots, with helpful examples from the text, plus a glossary and an appendix of normal biological values. Particularly valuable for students who are completely new to the subject, or returning to study after a period of absence, and for anyone whose first language is not English All new illustration programme brings the book right up-to-date for today’s student Helpful ‘Spot Check’ questions at the end of each topic to monitor progress Fully updated throughout with the latest information on common and/or life threatening diseases and disorders Review and Revise end-of-chapter exercises assist with reader understanding and recall Over 150 animations – many of them newly created – help clarify underlying scientific and physiological principles and make learning fun

Book Comprehensive Hypertension E Book

Download or read book Comprehensive Hypertension E Book written by Gregory Y. H. Lip and published by Elsevier Health Sciences. This book was released on 2007-06-28 with total page 1247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is today's most in-depth reference for any cardiologist, internist, or nephrologist interested in hypertension. Drawing from international experience in cardiology, physiology, and nephrology, Drs. Lip and Hall have assembled a group of section editors and contributors second to none. You'll find the long-term effects of primary and secondary hypertension and a lengthy section on hypertensions for special populations featured prominently. Prevention and treatment of hypertension are covered in detail, from lifestyle and diet issues to drug choice and delivery, and the section on comparison of guidelines is unique to this book. Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume. See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations. Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis. Get specific insight into prevention and treatment of hypertension in special populations. Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.

Book Nutrigenetics

Download or read book Nutrigenetics written by Martin Kohlmeier and published by Academic Press. This book was released on 2012-12-31 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrigenetics: Applying the Science of Personal Nutrition provides a fully referenced, readable guide to understanding the rationale and importance of nutrigenetic applications and explains why single nutrition recommendations will not fit everybody or even a majority of modern humans. This books explains how genetic variation shapes individual nutrition requirements and sensitivities, presents questions to ask about reported gene-nutrient interactions, and what needs to be done before putting nutrigenetic tests to practical use. This book blends key concepts from the fields of genetics, biochemistry, epidemiology, public health, and clinical medicine to give a rich perspective on the genetically diverse nutritional needs and sensitivities of individuals in health and disease. A steadily increasing number of people order genetic tests to find out what they should eat for better health, well being and performance, and an even greater number asks their healthcare providers about such tests. Most of the currently offered tests are not grounded in current knowledge, often absurdly so, but few professionals can explain why they are misguided. On the other hand, there are more evidence-supported genetic variants that can guide nutrition decisions, but again most healthcare providers know little about them, much less use them in their daily practice. There is a great need for a solidly evidence-based yet accessible book that explains the science of nutrigenetics and provides the tools to evaluate new nutrigenetic tests. Comprehensive coverage of the emerging science of nutritional genetics and its promise for individually tailored nutrition guidance Presents practical examples to enhance comprehension and spur additional research Offers a logical progression from what nutrigenetics is, to its possibilities in enhancing health

Book Disorders of Blood Pressure Regulation

Download or read book Disorders of Blood Pressure Regulation written by Adel E. Berbari and published by Springer. This book was released on 2018-01-25 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascular hypertension, endocrine hypertension, pediatric hypertension, and gestational hypertension. Other hypertension phenotypes, however, are not widely recognized, being reported only in special reviews; examples include hypertension associated with renal calculus disease and other rarer causes such as Turner syndrome, herbal and medicinal compounds, and pharmacologic agents. A detailed account of the various causes of monogenic hypertension is also included. Finally, a section is devoted to general aspects of hypertension, including the significance of blood pressure indices, the natural course of untreated and treated hypertension, hypertension mechanisms, genetics, and guidelines for blood pressure control.

Book Transcranial Doppler Sonography

Download or read book Transcranial Doppler Sonography written by Rune Aaslid and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every few years a dissertation comes to the area of clinical application of medical technology which carries us forward as on a magic carpet into new regions of understanding and patient care. This book is such a magic carpet. It brings together, in a clear and incisive fashion, important hemodynamic principles with a simple noninvasive method of application to a part of the cerebral vasculature which has been relatively inaccessible. To the lucky and perceptive person who reads this book, a feeling of excitement and hope for progress is engendered. The diligent application of the potentials of transcranial Doppler ultrasound brings new power to our efforts in understanding the cerebral circulation and the causes, treatment and prevention of cerebrovascular disorders. Merrill P. Spencer, M. D. Director Institute of Applied Physiology and Medicine Seattle, Wash. , July 1986 Acknowledgements I am greatly indebted to Prof. He1ge Nornes, Oslo, who introduced me to the fascinating study of cerebral hemodynamics in the early 1970's and since then continually encouraged my interest in this field. It was through his pioneering work on the cerebral circulation-using peroperative electromagnetic flowmetry and Doppler techniques-that the basis was laid for the noninvasive trans cranial approach to the circle of Willis described in this book. I also gratefully acknowledge the stimulating case discussions with Prof. Peter Huber, Berne, at the very early introduction of trans cranial Doppler, the inspiring exchange of ideas with Dr. Merrill P.

Book Skeletal Muscle Circulation

    Book Details:
  • Author : Ronald J. Korthuis
  • Publisher : Morgan & Claypool Publishers
  • Release : 2011
  • ISBN : 1615041834
  • Pages : 147 pages

Download or read book Skeletal Muscle Circulation written by Ronald J. Korthuis and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References

Book Fluid Resuscitation

    Book Details:
  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release : 1999-11-05
  • ISBN : 0309064813
  • Pages : 208 pages

Download or read book Fluid Resuscitation written by Institute of Medicine and published by National Academies Press. This book was released on 1999-11-05 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically, 20% of all injured combatants die on the battlefield before they can be evacuated to a field hospital. Blood lossâ€"hemorrhageâ€"is the single major cause of death among those killed in action whose lives might otherwise be saved. Fluid resuscitation and the treatment of hypovolemia (the abnormally decreased volume of circulating fluid in the body) offer the greatest opportunity for reducing mortality and morbidity associated with battlefield casualties. In Fluid Resuscitation, a committee of experts assess current resuscitation fluids and protocols for the treatment of combat casualties and make recommendations for future research. Chapters focus on the pathophysiology of acute hemorrhagic shock, experience with and complications of fluid resuscitation, novel approaches to the treatment of shock, protocols of care at the site of injury, and future directions for research. The committee explicitly describes the similarities and differences between acute medical care during combat and civilian emergency trauma care. Fluid Resuscitation should help energize and focus research in both civilian and military emergency care and help save the lives of citizens and soldiers alike.

Book The Adrenal Cortex

    Book Details:
  • Author : Geoffrey H. Bourne
  • Publisher :
  • Release : 2013-05
  • ISBN : 9781258726973
  • Pages : 328 pages

Download or read book The Adrenal Cortex written by Geoffrey H. Bourne and published by . This book was released on 2013-05 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Additional Contributors Include Roy O. Greep, Sarah A. Luse, Vincent Di Raimondo And Others.