Download or read book Homology written by Brian K. Hall and published by Elsevier. This book was released on 2013-10-22 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of homology varies depending on the data being examined. This volume represents a state-of-the-art treatment of the different applications of this unifying concept. Chapters deal with homology on all levels, from molecules to behavior, and are authored by leading contributors to systematics, natural history, and evolutionary, developmental, and comparative biology. This paperback reprint of the original hardbound edition continues to commemorate the 150th anniversary of Sir Richard Owen's seminal paper distinguishing homology from analogy. Commemoration of the 150th anniversary of Sir Richard Owen's seminal paper distinguishing homology from analogy Contributors who are renowned leaders in comparative biology Coverage that is both comprehensive and interdisciplinary

Download or read book Homology Genes and Evolutionary Innovation written by Günter P. Wagner and published by Princeton University Press. This book was released on 2018-07-10 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major synthesis of homology, written by a top researcher in the field Homology—a similar trait shared by different species and derived from common ancestry, such as a seal's fin and a bird’s wing—is one of the most fundamental yet challenging concepts in evolutionary biology. This groundbreaking book provides the first mechanistically based theory of what homology is and how it arises in evolution. Günter Wagner, one of the preeminent researchers in the field, argues that homology, or character identity, can be explained through the historical continuity of character identity networks—that is, the gene regulatory networks that enable differential gene expression. He shows how character identity is independent of the form and function of the character itself because the same network can activate different effector genes and thus control the development of different shapes, sizes, and qualities of the character. Demonstrating how this theoretical model can provide a foundation for understanding the evolutionary origin of novel characters, Wagner applies it to the origin and evolution of specific systems, such as cell types; skin, hair, and feathers; limbs and digits; and flowers. The first major synthesis of homology to be published in decades, Homology, Genes, and Evolutionary Innovation reveals how a mechanistically based theory can serve as a unifying concept for any branch of science concerned with the structure and development of organisms, and how it can help explain major transitions in evolution and broad patterns of biological diversity.

Download or read book Homology written by Novartis Foundation and published by Wiley. This book was released on 2008-04-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Homology' as a concept became increasingly elusive during the course of the 20th century. The central debates and controversies concern both fundamental definitions and the nature of the criteria by which homology is judged. Attempts to move away from comparative morphology to ideas based on developmental pathways have tended to founder on the fact that developmental pathways evolve and that similar cells or tissues or structures in animals will often have different developmental origins. The use of information about conserved molecules in seemingly conserved developmental processes has also proven controversial. In molecular biology, the use of the term 'homology' has given rise to more debate, although here the issue seems to involve primarily the criteria for assessing whether parts of genes are the same because of shared descent or for other reasons. The contributions to the book explore these topics systematically. There are chapters on the historical development of the concept of homology and its use in population studies. Other chapters deal with issues of homology in morphological and developmental studies, in behavioural studies, and especially in studies at the level of molecular genetics.

Download or read book Deep Homology written by Lewis I. Held, Jr and published by Cambridge University Press. This book was released on 2017-02-16 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comparison of the genetic circuits of Homo sapiens and Drosophila reveals the evidence for deep homology.

Download or read book Homology Modeling written by Andrew J. W. Orry and published by Humana Press. This book was released on 2012-02-10 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge about protein tertiary structure can guide experiments, assist in the understanding of structure-function relationships, and aid the design of new therapeutics for disease. Homology modeling is an in silico method that predicts the tertiary structure of an amino acid sequence based on a homologous experimentally determined structure. In, Homology Modelling: Methods and Protocols experts in the field describe each homology modeling step from first principles, provide case studies for challenging modeling targets and describe methods for the prediction of how other molecules such as drugs can interact with the protein. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Homology Modelling: Methods and Protocols guides scientists in the available homology modeling methods.

Download or read book Homoplasy written by Michael J. Sanderson and published by Elsevier. This book was released on 1996-10-21 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do unrelated organisms sometimes appear almost identical in details of the anatomy, behavior, physiology, and ecology? Homoplasy assembles leaders in evolutionary biology to explore issues of parallelism, convergence, and reversals. This innovative book is certain to provoke discussion of homoplasy compelling evidence for particular theories of evolutionary change The first book on this increasingly interesting subject Includes authoritative treatments from leading experts expressing a variety of viewpoints

Download or read book Homology Effects written by and published by Elsevier. This book was released on 2002-04-02 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homology Effects offers contributions from an international panel of researchers whose aim has been both to introduce newcomers to the field of homology effects, and to bring colleagues up to date. Topic coverage includes dosage compensation, X-inactivation, imprinting, paramutation, homology-dependent gene silencing, transvection, pairing-sensitive silencing, nuclear organization of chromosomes, DNA repair, quelling, RIP, RNAi and antisense biology, homology effects in ciliates, prion biology, and a discourse on the evolution of gene duplications. Advances in Genetics presents an eclectic mix of articles of use to all human and molecular geneticists. They are written and edited by recognized leaders in the field and make this an essential series of books for anyone in the genetics field. Homology, the examination of similarity due to shared common ancestry, encompasses a fascinating class of phenomena in mammals, plants, insects, ciliates, nematodes, fungi, and bacteria. Homology effects concern processes that recognize homology at the level of DNA and/or RNA, as well as at the level of protein. Their collective history begins at the turn of the century and includes some of the most puzzling and extraordinary observations in biology. The volume covers phenomena that have often been considered unusual, exceptional to the rule, and "out of the ordinary" and, therefore, not for general study. However, it is now becoming clear that taken together, these phenomena represent a class of regulatory mechanisms that are widespread, as well as exceptionally powerful.

Download or read book Homology of Cell Complexes written by George E. Cooke and published by Princeton University Press. This book was released on 2015-12-08 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in volume 4 of the Princeton University Press Mathematical Notes series. Based on lecture notes by Norman E. Steenrod. Originally published in 1967. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Download or read book Computational Protein Design written by Ilan Samish and published by Humana. This book was released on 2016-12-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim this volume is to present the methods, challenges, software, and applications of this widespread and yet still evolving and maturing field. Computational Protein Design, the first book with this title, guides readers through computational protein design approaches, software and tailored solutions to specific case-study targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Protein Design aims to ensure successful results in the further study of this vital field.

Download or read book Homology an Unsolved Problem written by Sir Gavin De Beer and published by . This book was released on 1971 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Sequence Evolution Function written by Eugene V. Koonin and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

Download or read book Homology Theory written by James W. Vick and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This introduction to some basic ideas in algebraic topology is devoted to the foundations and applications of homology theory. After the essentials of singular homology and some important applications are given, successive topics covered include attaching spaces, finite CW complexes, cohomology products, manifolds, Poincare duality, and fixed point theory. This second edition includes a chapter on covering spaces and many new exercises.

Download or read book Deep Homology written by Lewis I. Held, Jr and published by Cambridge University Press. This book was released on 2017-01-28 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans and flies look nothing alike, yet their genetic circuits are remarkably similar. Here, Lewis I. Held, Jr compares the genetics and development of the two to review the evidence for deep homology, the biggest discovery from the emerging field of evolutionary developmental biology. Remnants of the operating system of our hypothetical common ancestor 600 million years ago are compared in chapters arranged by region of the body, from the nervous system, limbs and heart, to vision, hearing and smell. Concept maps provide a clear understanding of the complex subjects addressed, while encyclopaedic tables offer comprehensive inventories of genetic information. Written in an engaging style with a reference section listing thousands of relevant publications, this is a vital resource for scientific researchers, and graduate and undergraduate students.

Download or read book Handbook of Paleoanthropology written by Winfried Henke and published by Springer Science & Business Media. This book was released on 2007-05-10 with total page 2057 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 3-volume handbook brings together contributions by the world ́s leading specialists that reflect the broad spectrum of modern palaeoanthropology, thus presenting an indispensable resource for professionals and students alike. Vol. 1 reviews principles, methods, and approaches, recounting recent advances and state-of-the-art knowledge in phylogenetic analysis, palaeoecology and evolutionary theory and philosophy. Vol. 2 examines primate origins, evolution, behaviour, and adaptive variety, emphasizing integration of fossil data with contemporary knowledge of the behaviour and ecology of living primates in natural environments. Vol. 3 deals with fossil and molecular evidence for the evolution of Homo sapiens and its fossil relatives.

Download or read book Homology written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Homology' as a concept became increasingly elusive during the course of the 20th century. The central debates and controversies concern both fundamental definitions and the nature of the criteria by which homology is judged. Attempts to move away from comparative morphology to ideas based on developmental pathways have tended to founder on the fact that developmental pathways evolve and that similar cells or tissues or structures in animals will often have different developmental origins. The use of information about conserved molecules in seemingly conserved developmental processes has also proven controversial. In molecular biology, the use of the term 'homology' has given rise to more debate, although here the issue seems to involve primarily the criteria for assessing whether parts of genes are the same because of shared descent or for other reasons. The contributions to the book explore these topics systematically. There are chapters on the historical development of the concept of homology and its use in population studies. Other chapters deal with issues of homology in morphological and developmental studies, in behavioural studies, and especially in studies at the level of molecular genetics.

Download or read book Oxford Biology Readers De Beer G Homology an unsolved problem written by John Juan Head and published by . This book was released on 1974 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Homology written by Saunders MacLane and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: In presenting this treatment of homological algebra, it is a pleasure to acknowledge the help and encouragement which I have had from all sides. Homological algebra arose from many sources in algebra and topology. Decisive examples came from the study of group extensions and their factor sets, a subject I learned in joint work with OTTO SCHIL LING. A further development of homological ideas, with a view to their topological applications, came in my long collaboration with SAMUEL ElLENBERG; to both collaborators, especial thanks. For many years the Air Force Office of Scientific Research supported my research projects on various subjects now summarized here; it is a pleasure to acknowledge their lively understanding of basic science. Both REINHOLD BAER and JOSEF SCHMID read and commented on my entire manuscript; their advice has led to many improvements. ANDERS KOCK and JACQUES RIGUET have read the entire galley proof and caught many slips and obscurities. Among the others whose sug gestions have served me well, I note FRANK ADAMS, LOUIS AUSLANDER, WILFRED COCKCROFT, ALBRECHT DOLD, GEOFFREY HORROCKS, FRIED RICH KASCH, JOHANN LEICHT, ARUNAS LIULEVICIUS, JOHN MOORE, DIE TER PUPPE, JOSEPH YAO, and a number of my current students at the University of Chicago - not to m~ntion the auditors of my lectures at Chicago, Heidelberg, Bonn, Frankfurt, and Aarhus. My wife, DOROTHY, has cheerfully typed more versions of more chapters than she would like to count. Messrs.