Download or read book Regulators and Effectors of Small GTPases Ras Family written by and published by Elsevier. This book was released on 2006-06-07 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase activating proteins or GAPs). In their active state, they interact with a continually increasing, functionally complex array of downstream effectors. Since the last Methods in Enzymology volume on this topic in 2000, the study of Ras Family GTPases has witnessed a plethora of new directions and trends. With regards to the founding member of the Ras superfamily, the study of Ras in oncogenesis has seen the development and application of more advanced model cell culture and animal systems. The discovery of mutationally activated B-Raf in human cancers has injected renewed interest in this classical effector pathway of Ras. - Includes a database for Ras family proteins and their effectors and regulators - Complimentary to volume 406 coverage of the Rho family - Over 150 international contributors

Download or read book Information Circular written by and published by . This book was released on 1999 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Carlson V Brandt written by and published by . This book was released on 2000 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biofouling of Spiral Wound Membrane Systems written by Johannes Simon Vrouwenvelder and published by IWA Publishing. This book was released on 2011-03-15 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of membrane biofouling has increased strongly in the past four years, compared to the previous twenty two years, indicated by the more than doubling of the number of scientific papers. However, no single source gives an updated overview of biofouling. Biofouling of Spiral Wound Membrane Systems gives a complete and comprehensive overview of all aspects of biofouling, bridging the gap between microbiology, hydraulics and membrane technology. High quality drinking water can be produced with membrane filtration processes like reverse osmosis (RO) and nanofiltration (NF). As the global demand for fresh clean water is increasing, these membrane technologies are increasingly important. One of the most serious problems in RO/NF applications is biofouling – excessive growth of biomass – affecting the performance of the RO/NF systems. This can be due to the increase in pressure drop across membrane elements (feed-concentrate channel), the decrease in membrane permeability or the increase in salt passage. These phenomena result in the need to increase the feed pressure to maintain constant production and to clean the membrane elements chemically. Biofouling of Spiral Wound Membrane Systems relates biomass accumulation in spiral wound RO and NF membrane elements with membrane performance and hydrodynamics and determines parameters influencing biofouling. It focuses on the development of biomass in the feed-concentrate (feed-spacer) channel and its effect on pressure drop and flow distribution. It can be used to develop an integral strategy to control biofouling in spiral wound membrane systems. Most past and present methods to control biofouling have not been very successful. An overview of several potential complementary approaches to solve biofouling is given and an integrated approach for biofouling control is proposed.

Download or read book Organizations and Strategies in Astronomy written by Andre Heck and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seated in a sun-lit corner of his 17th century Dutch house, his hand touching a celestial globe, Johannes Vermeer's "Astronomer" seems to pon der about the mysteries of the universe. We might make the trip to Paris and ask him, in the Louvre, what precisely is on his mind. Unfortunately, there will be no answer. But we do know what his mind was not on. It was not on the approaching deadlines for the proposals he would have to write for getting funds and telescope-time, not on the meeting of the observing programs committee, not on his refereeing duty for the journal Astronomy & Astrophysics, nor on his university's tightening budget for science. In the Kapteyn Institute at Groningen I stand face to face with the im pressive portrait of J.C. Kapteyn, painted in the year 1918. Seated at his desk he is doing his calculations with pen, pencil and tables, perhaps check ing the work of his skilled staff of human computers. Early in his career he had completed his magnum opus, the Cape Photographic Durchmusterung in collaboration with his close friend David Gill at Capetown, South Africa.

Download or read book Developing Basic Space Science World Wide written by Willem Wamsteker and published by Springer Science & Business Media. This book was released on 2004-03-31 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together the historical activities, the plans which have been developed over the past decade in the different nations, and the results which have materialized during this time in different developing nations. It aims to achieve for development agencies to be assisted in ways to find more effective tools for the application of development aid. The last section of the book contains a guide for teachers to introduce astrophysics into university physics courses. This will be of use to teachers in many nations.

Download or read book Standard Poor s Stock Reports written by and published by . This book was released on 2002 with total page 1434 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book School Social Work Worldwide written by Marion Huxtable and published by N A S W Press. This book was released on 2002 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book opens the boundaries of international school social work as never before. Sequentially arranged chapters allow practitioners, educators, and students to follow the expansion of school social work practice around the world. Leaders in the field from 12 countries provide eye-opening perspectives and interventions that are impressive in their range and application. Further, the book looks ahead to policy and practice issues for the future direction of the profession. The book makes a compelling statement about contemporary school social work -- the critical need for the international professional community to learn from one another so that all of our children can reach their full potential through education. It exemplifies the value of collaboration in developing the literature of the profession and raises issues for social work educators about including international themes in social work education.

Download or read book SEC Docket written by United States. Securities and Exchange Commission and published by . This book was released on 1992 with total page 946 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Archaea written by Roger A. Garrett and published by John Wiley & Sons. This book was released on 2008-05-12 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduced by Crafoord Prize winner Carl Woese, this volumecombines reviews of the major developments in archaeal researchover the past 10–15 years with more specialized articlesdealing with important recent breakthroughs. Drawing on majorthemes presented at the June 2005 meeting held in Munich to honorthe archaea pioneers Wolfram Zillig and Karl O. Stetter, the bookprovides a thorough survey of the field from its controversialbeginnings to its ongoing expansion to include aspects ofeukaryotic biology. The editors have assembled articles from the premier researchersin this rapidly burgeoning field, including an account by CarlWoese of his original discovery of the Archaea (until 1990 termedarchaebacteria) and the initially mixed reactions of the scientificcommunity. The review chapters and specialized articles address theemerging significance of the Archaea within a broader scientificand technological context, and include accounts of cutting-edgeresearch developments. The book spans archaeal evolution,physiology, and molecular and cellular biology and will be anessential reference for both graduate students and researchers.

Download or read book Journal of Cell Science written by and published by . This book was released on 2002 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Standard and Poor s SmallCap 600 Guide written by Standard & Poor's and published by McGraw-Hill Companies. This book was released on 2000-12 with total page 1238 pages. Available in PDF, EPUB and Kindle. Book excerpt: What do individual investors, money managers, analysts, brokers, and financial writers and editors have in common? All turn to Standard & Poor's, a division of the McGraw-Hill Companies, for securities information that is second to none. S&P's Guides, totally updated for 2002, deliver the same data and analyses used by today's top investment professionals. Each book puts these unique features at the reader's fingertips: -- Vital data on earnings, dividends, and share prices -- Key income and balance sheet statistics -- Exclusive S&P buy, sell, or hold recommendations for each stock -- Exclusive S&P outlook for every stock's price -- Computer-generated screens showing superior stock picks in different categories -- Company addresses, and numbers, and names of top officers The latest data for tracking America's fastest-rising companies.

Download or read book Medicinal Chemistry and Drug Discovery Chemotherapeutic agents written by Alfred Burger and published by . This book was released on 2003 with total page 1164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Hoover s Masterlist of Major U S Companies 1998 1999 written by Hoover's, Incorporated and published by Hoover's. This book was released on 1998 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide provides vital information on more than 5100 of the largest US public and private companies and other enterprises (government owned, foundations, schools, partnerships, subsidiaries, joint ventures, co-operatives and not-for-profits) with sales of more than $125 million, plus public companies with a market capitalization of more than $500 million.

Download or read book Montana Code Annotated written by Montana and published by . This book was released on 2016 with total page 1572 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Humanities Index written by and published by . This book was released on 2000 with total page 1608 pages. Available in PDF, EPUB and Kindle. Book excerpt: